Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
PRTG owns approximately 10%. Intensity Therapeutics is involved in two studies now. Phase 2 with Merck and Bristol Meyers. Phase 2 in Canada at the Ottawa Hospital. Here is the clinical study page for Intensity.
https://intensitytherapeutics.com/clinical-research/
I've been in this for quite awhile. Looks exciting over the next 30-90 days. Portage Biotech has a tremendous pipeline of drugs and the CEO and Management Team are mostly all ex-big pharma specialists. Ian Walters, the CEO is particularly worth doing some DD on.
It appears that Ian has purchased in excess of a million+ shares in a private transaction.
https://www.portagebiotech.com/ Lots to read here.
PTGEF has a new website up. I would suggest going onto twitter and follow Intensity an Sentien both owned by PTGEF. Intensity has been tweeting up a storm. They are also presenting at various conferences now. The price drop was most likely a signal that an uplist will come shortly. Remember a 120:1 reverse was approved. If that happens it should be in conjunction with an uplist. The latest PR last week hinted at leaving the OTC. I don't check this board often, so I won't be back for a few weeks. Here's to an excellent first Q2020.
One of the companies they have invested in is Intensity Therapeutics. The company presented data 14-15 in NYC. You can find more on Intensity's Twitter.
I agree with you. You can find an interview with the Intensity CEO by ForbesBooks, that highlights the company's progress. And that's just Intensity. SO I expect good things from this stock.
https://twitter.com/hashtag/BIOCEO19
I haven't had time to test this link yet. However it is a 25 minute interview with Lew Bender, the CEO of Intensity Therapeutics. It's worth giving it a listen. Just a small fraction of PTGEF's portfolio, and rather exciting waiting for continued clinical successes from this one.
If you can't link to it, you'll find it on Intensity's Twitter. Interview by Forbes_Books.
I did the same thing a couple weeks ago. Got filled when I raised my bid.
Same here.
This is a very good point. I'm in B*VN as a result of my investment in PTGEF. I had assumed the cost basis was the value of the stock dividend. I guess I DO need to speak to a tax expert. ROFL. I plan on holding both these companies for awhile. Nice to see people posting again.
The positive moves and news keep coming for this stock. News a couple days ago and the meeting in Jan. I really like PTGEF. And B*vn.
Well I am no tax expert, and I plan to hold as long as possible too. My thoughts on taxes are the same as yours...I expect the entire amount to be taxable.
Nice. B*vn announced Phase 3 news and it made a nice move this week. One target has it at $65. All to say I really like the management team behind PTGEF.
Yes confusing. Since we can't trade it, I believe they meant "trading will resume after the meeting concludes."
TORONTO, Nov. 21, 2018 /PRNewswire/ - (PBT.U: CSE, PTGEF: OTC Markets) - Further to its news releases of August 28 and October 9, 2018, Portage Biotech Inc. ("Portage" or the "Company") is pleased to announce that it has set a shareholder's meeting date to approve the Company's proposed acquisition of SalvaRx Limited from SalvaRx Group plc.
The meeting is scheduled for January 8th, 2019 for shareholders of record as of November 23, 2018. Meeting materials will be distributed shortly after the record date in accordance with the Notice-and-Access provisions of National Instrument 54-101 Communication with Beneficial Owners of Securities of a Reporting Issuer.
Trading in the shares of Portage is expected to resume on CSE shortly after the meeting materials have been posted.
Neither CSE nor its Market Regulator (as the term is defined in the policies of CSE) accepts responsibility for the adequacy or accuracy of this release.
This news release may contain forward looking statements concerning future operations of Portage Biotech Inc. (the "Company"). All forward looking statements concerning the Company's future plans and operations, including management's assessment of the Company's expectations or beliefs may be subject to certain assumptions, risks and uncertainties beyond the Company's control. Investors are cautioned that any such statements are not guarantees of future performance and that actual performance and financial results may differ materially from any estimates and projections.
Cision View original content:http://www.prnewswire.com/news-releases/portage-announces-setting-of-meeting-date-to-approve-salvarx-acquisition-300754058.html
SOURCE Portage Biotech Inc.
TORONTO, Nov. 27, 2018 /PRNewswire/ - (PBT.U: CSE, PTGEF: OTC Markets) – Further to its news release of November 21, 2018, Portage Biotech Inc. ("Portage" or the "Company") is very pleased to announce that it has published and posted its shareholder meeting materials which provide information regarding the rationale and key business terms for the proposed acquisition of SalvaRx Limited ("SalvaRx") from SalvaRx Group plc ("Group") (SALV.L) (see the Company's news release of August 14, 2018). The shareholder meeting is scheduled for January 8th, 2019 for shareholders of record as of November 23, 2018. Trading of the shares of Portage on CSE is expected to resume shortly.
Group is concurrently publishing their meeting materials for a shareholder meeting (also to be held on January 8th, 2019) to approve the sale of SalvaRx to Portage. These materials may be found on their website (https://www.salvarx.io/investors/regulatory-news.html).
Since the initial announcement of the proposed purchase of SalvaRx on August 14, 2018, Intensity Therapeutics Inc. ("Intensity"), one of SalvaRx's portfolio assets, has announced that results from its Phase I clinical trial IT-01 were selected for presentation at two international meetings: the European Society of Medical Oncology (ESMO) 2018 Congress in Munich, Germany on October 23rd and the Society of Immunotherapy Conference (SITC) in Washington DC on November 8th. The preliminary data from their Phase 1/2 clinical study demonstrated that INT230-6, Intensity's novel lead product candidate designed for direct intratumoral injection, was well tolerated in patients with advanced solid tumors. In addition, preliminary efficacy data revealed that even at low doses, some anti-tumor effects were noted in injected tumors, as well as some evidence of immune activation as evidenced by biomarker changes in the blood and anti-tumor effects in distal, untreated tumors. These findings confirm the exciting data demonstrated in animal models.
Intensity also announced that its Series B financing covering the further buildout of its clinical program was completed at a 250% premium to SalvaRx's investment in Series A. Further details can be found at: https://intensitytherapeutics.com/media/#media-group-press-releases.
Intensity's product is the most advanced in the SalvaRx portfolio.
Should shareholders of Portage approve the acquisition of SalvaRx, the combined Portage/SalvaRx oncology portfolio will include 11 drugs in discovery and development.
SalvaRx's early phase products have been making progress towards clinical trials. This oncology franchise represents a key strategic decision to focus on an experienced team with deep domain expertise activating the immune system to fight cancer. In line with their experience in cancer immunotherapy and in anti-inflammatory therapeutics, Portage management are evaluating technologies an adjacent area on how the immune system can be regulated by the microbiome in the gut.
Diverse Oncology Pipeline (CNW Group/Portage Biotech Inc.)
Diverse Oncology Pipeline (CNW Group/Portage Biotech Inc.)
Portage, its management team, and its board of directors are confident that the acquisition of SalvaRx will solidify its strategic path forward. Like the success seen with Biohaven under Dr. Coric's leadership, Portage believes it has found an excellent team with the commercial and development expertise required to advance these novel technologies towards clinical proof of concept and to unlock the value behind these products.
Portage invests in Stimunity S.A, a Paris-based cancer immunotherapy companyPR Newswire
PR Newswire•February 28, 2018
TORONTO, Feb. 28, 2018 /PRNewswire/ - Portage Biotech Inc. ("Portage" or "the Company") (Canadian Securities Exchange: PBT.U, OTC Markets : PTGEF), is pleased to announce that it has made an investment in Stimunity, SAS ("Stimunity"), a Paris-based immuno-oncology company. Portage's will invest up to €2,000,000 subject to the successful completion of milestones. Stimunity will use the proceeds of this seed round to fund the preclinical development of its lead product, a potent biologic enhancer of the STING pathway that activates the immune system against tumor cells.
"The discovery of cancer checkpoint immunotherapy has made huge improvements in the treatment of multiple cancer types, particularly in highly inflamed tumors. However, typically 50% or more of patients won't respond and require better treatment options," said Dr. Ian B. Walters, a board member of Portage. "Scientists are searching for safe and effective agents to augment checkpoint activity, and drive long term responses in resistant tumors."
Stimunity's lead candidate is a Virus-Like Particle ("VLP") encapsulating the natural agonist of STING; these VLPs will fuse with immune cells and induce a potent T-cell response against tumor cells that are poorly immunogenic. The lead program is now at the early phase of preclinical validation. Nicolas Manel PhD, Stimunity's co-founder and the co-inventor of its technology is very confident, saying, "Early in vivo data shows that our approach synergizes with immune checkpoint therapies and leads to a potent therapeutic effect on distant tumors which is what most of patients need."
"The collaboration between Stimunity and Portage opens another chapter for Portage, providing the company with a program advancing into human testing. Stimunity's technology has the potential to stimulate the tumor microenvironment and promote an immune response in a safer and more potent fashion than other STING agonists. We believe these properties will enable Stimunity's STING agonists to become an important adjuvant to checkpoint inhibitors in non-immunogenic tumor types," said Greg Bailey, Chairman of Portage.
Stimunity's seed round will help the company complete its preclinical package and advance the manufacturing process used to create its virus-like particles to pharmaceutical grade. Dr. Ian B. Walters will chair Stimunity's Board of Directors. "We are very excited by our collaboration with Portage; it not only brings significant investment to the table, but also provides strong expertise in immuno-oncology and clinical development. We are happy to welcome Ian onto our board." said Sylvain Carlioz, co-founder and CEO of Stimunity.
About Stimunity
Stimunity is an early-stage research and development company focused on the development of STING agonists in cancer. The technology, licensed from Institut Curie, Inserm, and the University of Oxford, is based on a unique biologic approach which encapsulates endogenous STING-activating molecules in a Virus-Like Particle (VLP). Stimunity's drug has the potential to be best-in-class, activating the innate immune system and enhancing T-cell response against tumor cells with low immunogenicity.
More information at:
http://stimunity.com
contact@stimunity.com
About Portage
Portage is engaged in supporting the discovery and development of pharmaceutical and biotech products through clinical "proof of concept" with a focus on areas of unmet clinical need. Following proof of concept, Portage will seek to sell or license these products to large pharmaceutical or biotechnology companies for further development and commercialization. Portage has an interest in novel targeted therapies, stem cell therapies, and new indications for older marketed products that have been found to have novel patentable characteristics that bring new value to patients.
Forward-Looking Statements
This news release includes forward-looking statements within the meaning of the U.S. federal and Canadian securities laws. These forward-looking statements involve substantial risks and uncertainties, including statements that are based on the current expectations and assumptions of the Company's management. All statements, other than statements of historical facts, included in this press release, are forward-looking statements. The use of certain words, including the "believe", "could", "expect" and "will" and similar expressions are intended to identify forward-looking statements. The Company may not actually achieve the plans and objectives disclosed in the forward-looking statements and you should not place undue reliance on the Company's forward-looking statements. Various important factors could cause actual results or events to differ materially from those that may be expressed or implied by our forward-looking statements, including uncertainties relating to the future clinical success. Additional important factors to be considered in connection with forward-looking statements are described in the "Risk Factors" section of the Company's quarterly financials and Management Discussion and Analysis and annual Report in Form 20-F filed on SEDAR and EDGAR. The forward-looking statements are made as of this date and the Company does not undertake any obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.
Portage 's PPL forms a joint venture with University of Glasgow to develop new peptide therapeutics
PR Newswire PR Newswire•February 2, 2018
TORONTO, Feb. 2, 2018 /PRNewswire/ - Portage Biotech Inc. ("Portage") (OTCQB: PTGEF, Canadian Stock Exchange: PBT.U) is pleased to announce that its wholly owned subsidiary, Portage Pharmaceuticals Ltd. ("PPL'), has formed a new joint venture company, Portage Glasgow Limited ("PGL"), incorporated in Scotland, to develop more effectively-targeted drugs to treat chronic conditions including cancer.
PPL will hold controlling interest in PGL.
Portage Pharmaceuticals is providing an undisclosed funding to the new business along with a limited license to its CellPorter™ peptide delivery technology.
The University of Glasgow is providing therapeutic peptides developed through the research of Prof. George Baillie and access to a therapeutic peptide discovery platform.
PGL will focus on the commercialisation of new therapies aimed at disrupting protein-protein interactions (PPI) in disease pathways which give therapeutic benefit. Candidate peptides and PPI targets have already been identified from existing research at the University.
Dr Frank W. Marcoux is a founding Director and the CEO of PGL. He currently serves as the Chief Executive Officer and Chief Scientific Officer of Portage Pharmaceuticals Ltd. and has over 25 years of drug development experience in a variety of senior management roles at Pfizer and Parke-Davis, culminating with an eight year tenure as Vice President, Pfizer Global Research and Development.
Professor George Baillie is the academic founding director of the company. He is the Professor of Molecular Pharmacology at the University of Glasgow's Institute of Cardiovascular and Medical Sciences and worked for 15 years on publically and privately-funded research in phosphodiesterase enzymes and protein-protein interactions.
Dr. Declan Doogan, CEO of Portage commented, "'This is a great example of a collaboration between commercial drug developers and academic researchers who have the potential to deliver truly cutting edge much needed treatments to patients world wide. I am excited to be associated with this Glasgow based enterprise. "
Dr. Gregory Bailey, Chairman of Portage commented. "Our joint venture with Glasgow is not only part of the evolution of PPL, but also the beginning of the next chapter for Portage Biotech. We are looking for compelling products or companies that our team can add value to. Portage Biotech will be pathology agnostic and will evaluate new companies opportunistically".
Please also refer to the News Release dated January 31, 2018 by the University of Glasgow which can be found at www.glasgow.ac.uk.
About Portage
Portage is engaged in the discovery and development of pharmaceutical and biotech products through clinical "proof of concept" with a focus on areas of unmet clinical need. Following proof of concept, Portage will seek to sell or license these products to large pharmaceutical or biotechnology companies for further development and commercialization. Portage has an interest in novel targeted therapies, stem cell therapies, and new indications for older marketed products that have been found to have novel patentable characteristics that bring new value to patients.
Forward-Looking Statements
This news release includes forward-looking statements within the meaning of the U.S. federal and Canadian securities laws. These forward-looking statements involve substantial risks and uncertainties, including statements that are based on the current expectations and assumptions of the Company's management. All statements, other than statements of historical facts, included in this press release, are forward-looking statements. The use of certain words, including the "believe", "could", "expect" and "will" and similar expressions are intended to identify forward-looking statements. The Company may not actually achieve the plans and objectives disclosed in the forward-looking statements and you should not place undue reliance on the Company's forward-looking statements. Various important factors could cause actual results or events to differ materially from those that may be expressed or implied by our forward-looking statements, including uncertainties relating to the future clinical success. Additional important factors to be considered in connection with forward-looking statements are described in the "Risk Factors" section of the Company's quarterly financials and Management Discussion and Analysis and annual Report in Form 20-F filed on SEDAR and EDGAR. The forward-looking statements are made as of this date and the Company does not undertake any obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.
I can't seem to find BlocPal International. Any else see it online?
There is nothing fishy going on. Read the News about PTGEF and BHVN and it will explain everything.
Waiting.
TORONTO, Dec. 4, 2017 /PRNewswire/ - Portage Biotech Inc. ("Portage") (OTCQB: PTGEF, Canadian Stock Exchange: PBT.U) announces that the Board of Directors of Portage has approved the previously announced distribution of Biohaven Pharmaceutical Holding Company Ltd. ("Biohaven") shares (NYSE:BHVN) held by Portage to its shareholders by way of a stock dividend and has fixed the record date for the distribution as January 5, 2018 (the "Record Date") with the distribution to be effected on January 15, 2018. The Board has approved the stock distribution in order for Portage to avoid being characterized as an "investment company" under the U.S. Investment Company Act of 1940 (the "ICA"). This characterization would require Portage to comply with the rules and regulations under the ICA, which are not consistent with Portage's business purposes.
Three of Portage's directors, Dr. Gregory Bailey, Dr. Declan Doogan and Mr. James Mellon, who collectively own approximately 53% of Portage's outstanding shares and will, therefore, receive approximately 53% of the Biohaven shares to be distributed, have agreed to sign a voluntary standstill arrangement not to sell 90% of the Biohaven shares they will receive pursuant to the dividend until after Biohaven announces topline results of its first two ongoing phase 3 clinical trials of rimegepant. Portage has reserved a total of approximately 6 million Biohaven shares for the distribution. For every 46 Portage shares held on the Record Date, one share of Biohaven will be distributed on January 15, 2018.
Dr. Doogan said "in the best interests of Portage, we are disposing of its interest in Biohaven so as to avoid being designated as an investment company under the ICA. However, in response to wishes expressed by many of our shareholders that we not sell Biohaven shares in advance of Biohaven's rimegepant phase 3 trial readout[s], we are distributing the Biohaven shares. In this way, Portage shareholders will receive shares of Biohaven and will be able to decide for themselves whether to wait for the announcement of Biohaven's Phase 3 clinical trial results, which is currently expected in the first quarter of 2018."
Summary of Distribution:
Ratio of distribution:
One Biohaven share will be distributed for every 46 Portage shares held on the Record Date.
Fractional shares:
No fractional shares, or cash in lieu of fractional shares, will be distributed. Rather, the number of Portage shares held by a Portage shareholder as of the Record Date will be rounded to the nearest 46 share increment to determine the number of whole Biohaven shares such shareholder will receive in the distribution. As a result, one Biohaven share will be distributed in respect of 23 to 45 incremental Portage shares held as of the Record Date and no consideration will be distributed in respect of fewer than 23 incremental Portage shares held as of the Record Date.
Distribution date:
January 15, 2018
SHAREHOLDERS ARE ADVISED TO CONSULT THEIR OWN TAX ADVISORS REGARDING THE CONSEQUENCE OF THE PROPOSED DISTRIBUTION.
About Portage
Portage is engaged in the discovery and development of pharmaceutical and biotech products through clinical "proof of concept" with a focus on areas of unmet clinical need. Following proof of concept, Portage will seek to sell or license these products to large pharmaceutical or biotechnology companies for further development and commercialization. Portage has an interest in novel targeted therapies, stem cell therapies, and new indications for older marketed products that have been found to have novel patentable characteristics that bring new value to patients.
Forward-Looking Statements
This news release includes forward-looking statements within the meaning of the U.S. federal and Canadian securities laws. These forward-looking statements involve substantial risks and uncertainties, including statements that are based on the current expectations and assumptions of the Company's management. All statements, other than statements of historical facts, included in this press release, including Biohaven's timing of the expected data readouts from the Company's registrational trials of rimegepant, are forward-looking statements. The use of certain words, including the "believe", "could", "expect" and "will" and similar expressions are intended to identify forward-looking statements. The Company may not actually achieve the plans and objectives disclosed in the forward-looking statements and you should not place undue reliance on the Company's forward-looking statements. Various important factors could cause actual results or events to differ materially from those that may be expressed or implied by our forward-looking statements, including uncertainties relating to the future clinical success of rimegepant, and whether the results observed in the Phase 2b clinical trial will be observed in the Phase 3 pivotal trials. Additional important factors to be considered in connection with forward-looking statements are described in the "Risk Factors" section of the Company's quarterly financials and Management Discussion and Analysis and annual Report in Form 20-F filed on SEDAR and EDGAR. The forward-looking statements are made as of this date and the Company does not undertake any obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.
SOURCE Portage Biotech Inc.
Copyright (C) 2017 PR Newswire. All rights reserved
I'm out of this one for now. If they release a solid update with numbers, will look at entering.
BHVN is an investor in Kleo. And PTGEF owns slightly less than a third of BHVN...read on.
July 18, 2017
PeptiDream and Kleo Pharmaceuticals Announce Collaboration Agreement to Develop Novel Immunotherapies for Oncology
New Haven, CT – July 18, 2017
PeptiDream Inc., a public Tokyo-based biopharmaceutical company (“PeptiDream”)(TOKYO:4587) and Kleo Pharmaceuticals Inc., a New Haven-based company using its proprietary Antibody Recruiting Molecule (“ARM”) and Synthetic Antibody Mimic (“SyAM”) platform technologies to develop small molecule immunotherapies (“Kleo”), announced today a collaboration agreement to co-develop proprietary immune-oncology products in multiple indications.
Under the terms of the agreement, PeptiDream will use its proprietary Peptide Discovery Platform System (“PDPS”) technology to identify macrocyclic/constrained peptides against multiple oncology targets of interest selected by Kleo, and to optimize hit peptides into optimized binders that will be engineered by Kleo into novel ARM and SyAM products. Kleo will receive an upfront payment and will have the right to develop and commercialize all compounds resulting from the collaboration. PeptiDream is eligible to receive a tiered share of proceeds from any products that arise from the collaboration based on degree to which PeptiDream funds development of the product. Specific financial terms were not disclosed.
“We are very excited to enter into this collaboration agreement with PeptiDream ,” said Douglas Manion, MD, CEO of Kleo. “We think combining PeptiDream’s PDPS technology with Kleo’s ARM and SyAM platform represents a truly potent partnership that will generate many more effective targeted treatments for patients. We are looking forward to advancing this new paradigm of small molecule immunotherapies into the clinic.”
“PeptiDream has long been on the forefront of transforming PDPS-identified peptides into peptide therapeutics, small molecule drugs, and peptide drug conjugates (PDCs),” said Keiichi Kubota, CEO of PeptiDream. “We greatly look forward to working with innovative leaders like Kleo to leverage our capabilities to develop the next generation of first-in-class and best-in-class immunotherapies.”
About Kleo Pharmaceuticals Inc.
Kleo Pharmaceuticals Inc. is a biotechnology company initially formed on the basis of intellectual property from the Spiegel Lab at Yale University and funded by a series A round led by Biohaven Pharmaceuticals Holding Ltd (NYSE: BHVN) . The company was founded by Dr. David Spiegel and Roy Prieb and is focused on developing a new class of targeted immunotherapies. The company is based in New Haven, CT. Further information regarding Kleo can be found at: http://kleopharmaceuticals.com.
About PeptiDream
PeptiDream Inc. is a public (Tokyo Stock Exchange 1st Section 4587) biopharmaceutical company founded in 2006 employing our proprietary Peptide Discovery Platform System(PDPS), a state-of-the-art highly versatile discovery platform which enables the production of highly diverse (trillions) non-standard peptide libraries with high efficiency, for the identification of highly potent and selective hit candidates, which then can be developed into peptide-based, small molecule-based, or peptide-drug-conjugate-based therapeutics. PeptiDream aspires to be a world leader in drug discovery and development to address unmet medical needs and improve the quality of life of patients worldwide. Further information regarding PeptiDream can be found at: http://peptidream.com
Forward-Looking Statements
This news release includes forward-looking statements within the meaning of the U.S. federal and Canadian securities laws. These forward-looking statements involve substantial risks and uncertainties, including statements that are based on the current expectations and assumptions of the Company's management. All statements, other than statements of historical facts, included in this press release regarding the Company's plans and objectives, expectations and assumptions of management are forward-looking statements. The use of certain words, including the words "estimate," "project," "intend," "expect," "believe," "anticipate," "will,” "plan," "could," "may" and similar expressions are intended to identify forward-looking statements. The Company may not actually achieve the plans, intentions or expectations disclosed in the forward-looking statements and you should not place undue reliance on the Company's forward-looking statements. Various important factors could cause actual results or events to differ materially from those that may be expressed or implied by our forward-looking statements including receipt of regulatory approvals and market conditions. The forward-looking statements are made as of this date and the Company does not undertake any obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise.
TORONTO, July 12, 2017 /PRNewswire/ - Portage Biotech Inc. ("Portage" or "the Company") (OTC: PTGEF, Canadian Securities Exchange: PBT.U), provides below a summary of voting results of the Annual and Special meeting ("ASM") of its shareholders held on July 6, 2017:
According to the transfer agent's reports, being present in person or by proxy, were the holders of 188,839,277 common shares, or 72.44% of the issued and outstanding common shares on May 18, 2017, the record date for the ASM. The following matters put to vote were approved:
1.
Appointment of six nominated directors for the ensuing year, namely Dr. Declan Doogan, Dr. Gregory Bailey, Mr. James Mellon, Mr. Kam Shah, Mr. Steven Mintz and Dr. Ian Walters.
In favor: 99.87%, Against: Nil, Abstained: 0.13%
2.
Reappointment of Schwartz Levisky Feldman LLP as auditors for the ensuing year and to authorize the directors of the Company to fix their remuneration.
In favor: 99.85%, Against: Nil, Abstained: 0.15%
3.
Authorization to the directors of the Company to initiate, at their discretion, a consolidation of Portage's common shares such that one new share to be issued in exchange for up to eighty existing common shares. Directors have also been authorized to decide if and when to affect such consolidation.
In favor: 99.66%, Against: 0.34%, Abstained: nil
4.
Adoption of the amended Memorandum and Articles of Association of the Company
In favor: 99.82%, Against: 0.18%, Abstained: nil
Portage is pleased to provide the following update on its portfolio companies:
Biohaven Pharmaceutical Holding Company Ltd ("Biohaven")
Portage holds 6,341,500 common shares in Biohaven which trades on New York Stock Exchange under a trading symbol "BHNV"
Biohaven's goal is to become a leader in the development of innovative therapies for neurological diseases that have the potential to change current treatment paradigms.
The key elements of the strategy are
Rapidly advance and commercialize their portfolio of migraine product candidates. In the second half of 2017, they expect to initiate two Phase 3 clinical trials with rimegepant for the acute treatment of migraine, with topline results expected in the first quarter of 2018.
They are also planning a 12-month, long-term safety study of rimegepant to meet FDA requirements for approval. They are designing their Phase 3 development program to support regulatory approval in the United States, as well as to support regulatory filings in Europe and Japan.
Complete the development and commercialization of their novel glutamate modulator trigriluzole as potentially the first FDA-approved drug treatment for patients suffering from ataxias. They anticipate receiving topline results of our Phase 2/3 clinical trial of trigriluzole in SCA in the first quarter of 2018 and, if positive, submitting an NDA in 2018. They designed their Phase 2/3 clinical trial to support regulatory approval in the United States as well as to support regulatory filings in Europe and Japan.
Demonstrate bioequivalence and prepare for commercialization of their low-dose, oral disintegrating sublingual product candidate, BHV-0223, for ALS patients. They plan to launch a study to compare the bioequivalence of their sublingually absorbed ODT formulation of riluzole, BHV-0223, to orally delivered riluzole tablets and subsequently submit an NDA in 2018.
Advance BHV-5000 into clinical trials to assess its potential to be the first approved treatment for patients suffering from breathing irregularities associated with Rett syndrome. After a confirmatory Phase 1 clinical trial to bridge pharmacokinetics with the prior formulation, they plan to initiate a Phase 2/3 clinical trial in Rett syndrome in 2018.
Maximize the therapeutic and commercial potential of their existing product candidates by exploring their use for multiple indications. Based on the broad mechanistic potential of the glutamate modulation platform, they believe that their product candidates may have utility in a wide array of conditions. They plan to explore the use of their product candidates in additional therapeutic indications where glutamate plays a central role in the pathophysiology of disease, including anxiety and mood disorders.
Actively manage their product portfolio and opportunistically enter into strategic collaborations. They plan to retain their worldwide commercialization rights for some of their key product candidates while for other product candidates they will consider partnership opportunities to maximize returns. Leveraging their management team's deep large pharma relationships and experience will be a key component of this strategy.
Sentien Biotechnologies Inc. ("Sentien")
Portage invested $700,000 in August 2015 to acquire 210,210 series A preferred stock in Sentien, fully convertible into equal number of Sentien's common shares, representing currently approximately 6.3% of Sentien's equity.
Sentien Biotechnologies, Inc. is a privately-owned, clinical-stage company pioneering new approaches to cell therapy. Sentien's technology harnesses the power of cell therapy with innovative drug delivery systems to treat a wide range of systemic inflammatory diseases. Sentien's lead product, SBI-101, is designed to allow for controlled, sustained delivery of mesenchymal stromal cell (MSC) secreted factors. This approach immobilizes the MSCs in an extracorporeal device, allowing for doses of therapeutic factors that are unattainable by direct injection.
SBI-101 is the first product application of Sentien's platform blood-conditioning technology that has the potential to restore balance to the immune system after acute vital organ injury, such as acute kidney injury.
In April 2017, Sentien announced closure of a new $12 million financing by third party Biotech funds and also announced that its investigational new drug (IND) application for its lead product, SBI-101, received clearance from the U.S. Food and Drug Administration. On June 8, 2017, Sentien announced that it opened enrollment in its Phase ½ trial of SBI-101 for adult patients with acute kidney injury (AKI).
The multi-center trial is a randomized, controlled Phase 1/2 study in patients with AKI receiving CRRT. The primary objective of the trial is to evaluate the safety and tolerability of SBI-101 in patients with AKI. Endpoints for efficacy and pharmacodynamic responses to SBI-101 therapy will also be evaluated. Patient recruitment is expected to continue into 2018, with an estimated enrollment of 24 patients.
Portage Pharmaceuticals Ltd (PPL) and EyGen Limited (EyGen)
PPL and EyGen are fully owned subsidiaries of Portage.
PPL/EyGen completed work with BioConcept Laboratories on a drug product formulation for PPL-003 Ophthalmic solution that will be used for IND enabling non-clinical studies and phase I and phase IIA clinical studies. BioConcept Laboratories also completed short-term stability testing of PPL-003 ophthalmic solution. PPL decided that it would use chemical synthesis methods for drug substance going forward and discontinue production in recombinant E. coli. Also during June 2017, PPL/EyGen completed work on a pre-IND meeting briefing document and issued a letter to FDA requesting a pre-IND meeting. PPL also completed a research agreement with the University of Houston for evaluation of PPL-003's NFkB inhibitory mechanism in corneal epithelial cells.
In addition to advancing the PPL-003 ophthalmic solution project for dry eye disease and other inflammatory eye diseases, PPL has continued to work on other drug products that utilize its proprietary CellPorter® technology including two cancer candidates, PPL-008 and PPL-009. Lastly, PPL also continues work to support its patent applications and develop academic and industry collaborations.
About Portage:
Portage is engaged in the discovery and development of pharmaceutical and biotech products through clinical "proof of concept" with a focus on areas of unmet clinical need. Following proof of concept, Portage will seek to sell or license these products to large pharmaceutical or biotechnology companies for further development and commercialization. Portage has an interest in novel targeted therapies, stem cell therapies, and new indications for older marketed products that have been found to have novel patentable characteristics that bring new value to patients.
You are exactly right.
Baadshah Gaming and Mojo Games, a Division of Sterling Group Ventures, Announce Strategic Partnership to Provide the Back Office and Online Poker to Baadshah Gaming
Newsfile Corp.
Newsfile Corp
Vancouver, British Columbia--(Newsfile Corp. - May 16, 2017) - Mojo Games, a division of Sterling Group Ventures (OTCQB: SGGV) is pleased to announce a strategic partnership between its wholly owned subsidiary Mojo Interactive Services India Private Ltd. and Oceanking Software Solutions LLP, for its brand Baadshah Gaming, an Indian corporation who is the first of its kind to offer a multi-game online portal within India.
The partnership between Baadshah and Mojo has been formed as part of an online strategy to support Baadshah's efforts to become Indias first online portal to seamlessly provide Poker and Daily Fantasy. Baadshah aims at changing the perception of games of skill from being a leisure activity to a more professional carrier oriented one. Currently, Baadshah offers Poker and the Fantasy Cricket League and they will be enhancing their Fantasy League experience for online gaming enthusiasts.
Madhav Gupta, Co-Founder, Baadshah, said:
"We are very excited to be working with Mojo and chose to partner with them for their advanced iGaming platform and poker solutions. After considering several options, the Mojo solution was a clear winner as it gives us a lot of flexibility and allows for seamless integration of our proprietary products. We look forward to growing our online gaming network with Mojo Games."
Nick Mellios, CEO, Mojo, said:
"We are very pleased and fortunate to have such a strong partner like Baadshah Gaming in India. We truly believe that market opportunity and potential for growth in revenue in India is immense and is just beginning. The Mojo platform is very customizable and includes all the major Indian payment processing options. We are fully committed to investing in our partnership with Baadshah Gaming and are in the process of adding additional languages and enhanced features to our platform."
About Mojo Games, a division of Sterling Group Vent ures
Mojo Games provides a B2B multi-gaming platform with a full suite of social play money gaming products, including online poker. Mojo offers B2B partners both API integrated and turnkey white label licensing options with advanced and customizable iGaming back-office features, player rewards and marketing, affiliate, and ecommerce solutions.
About Baadsah Gaming
Baadshah Gaming is a first of its kind online portal in India that offers Poker and Fantasy League under one roof. It aims at changing the perception of game of skills from being only a leisure activity to a career avenue.
ON BEHALF of the BOARD
/s/ Nicolaos Mellios
______
Mr. Nicolaos Mellios
Chairman & CEO, Sterling Group Ventures
For further information, please contact:
Sterling Group Ventures
Chris MacPherson, CFO
Phone: (604) 564-0765
www.mojo.game
Baadshah Gaming
Madhav Gupta, Co-Founder
https://www.baadshahgaming.com
Any forward-looking statement in this press release is made pursuant to the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Investors are cautioned that actual results may differ substantially from such forward-looking statements. Forward-looking statements involve risks and uncertainties including, but not limited to, economic and political factors, product prices and changes in international and local markets, as well as the inherent risks of the mining related business. There can be no assurance that such statements will prove to be accurate as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on forward-looking statements. Cautionary Note to U. S. Investors Concerning Estimates of Measure d , Indicated, and Inferred Resources and Reserves. Statements regarding resources and reserves have been based on audits conducted under Chinese methods of calculation which the SEC guidelines strictly prohibit in its filings.
http://www.newsfilecorp.com/newsinfo.php?i=26831&f=96
Watching closely. Lots of good news coming I believe.
Apparently it was a software issue and a number of stocks were affected.
Not quite sure what is up. But I stated paying attention real fast.
Ask at .0899
So my Schwab is showing a bid at .95 also. Crazy times ahead?
http://www.esselgroup.com Scanning around, extensive website, not a lot of details.
News out. Interesting. The deal is for India, no news on Ihub. Released at 2 p.m pacific time.
Thanks for finding this. Updated with current info. Starting to get an idea what these guys do.
That sounds about right. And it has been great to see them hitting deadlines.
Just sent an email myself, so let's see if I get anything back. With the deadline coming up, no news, may be good news. Maybe.
Great. I hope they respond soon.
I spoke with Raul a couple years back, then Chris took over. Has anyone here had a chance to speak with him (Chris) in the last 6 months?