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Typ,
Looking back, they were trying to make as much money as possible for their cronies because they knew they it would take years to reach phase II and III. Eric was apparently involved in the PIPES. We checked his other company that was involved with PPHM. So they were trying to make as much money as possible upfront for themselves and have not been not interested in licensing anything until now and now you would think that they can make a lot more money by getting a deal done.
That's the hope. They own/run the company, we are just retail tools to them. We could have invested the money elsewhere or kept it in the bank.
I don't see how this proposal could help in any way. Nothing else in the past did anything other than the time when they options got voted down.
Chinese scientists develop live H5N1 vaccine for human
I will be waiting for the unleaded american vaccine, hopefully with the help of PPHM.
Did the chinese use their own technology or was it pirated like they do with software, music CDs. DVDs, designer clothes, handbags, watches, medicines and a lot more.
HARBIN, May 1 (Xinhua) -- Chinese scientists have developed a live human bird flu vaccine after more than three years of research on animals, a chief researcher said here Friday.
Tests of the cold-adapted, live attenuated H5N1 vaccine in mice and nonhuman primates showed that the vaccine provided complete protection in the animals against homologous and heterologous H5N1virus challenge, said Chen Hualan, director of China's National Avian Influenza Reference Laboratory, who is in charge of the research.
"Our study represents a major advance in vaccine development for H5N1 pandemic influenza and we are very confident about its prospect," Chen told Xinhua in an exclusive interview.
Chen said the new type of vaccine "has many revolutionary improvements" in terms of its protective efficacy, production technique, and usage.
Vaccinated rhesus macaques remained healthy after they were injected with H5N1 virus as the vaccine stops the replication of the virus. But those infected animals without vaccination showed symptoms of fever, pneumonia and inappetence, similar to human infections.
Chen's team started the research and experiments in 2005, after a domestic epidemic that caused huge losses for poultry breeders.
The research results of the new vaccine was published on Friday's edition of the PLoS Pathogens, an international journal published by the Public Library of Science (PLoS).
H5N1 influenza viruses have infected 421 people, including 257 killed, in 15 countries with a high fatality of 61 percent.
Therefore, the development of effective vaccines is a priority for H5N1 pandemic preparedness, according to the article.
Human vaccines had been generated in some regions in the world. China's food and drug regulators authorized a Beijing-based pharmaceutical firm to begin commercial production of a human bird flu vaccine in April last year.
A high dosage of adjuvants improve the immunogenicity of H5N1 inactivated vaccines, but limited production capacity for conventional inactivated influenza virus vaccines could severely hinder the ability to control the spread of H5N1 influenza through vaccination, Friday's article pointed out.
The vaccine becomes effective by just spraying it into people's noses.
Production of the live vaccines requires much less chicken embryos than the traditional inactivated vaccines, which allows large-scale production and massive storage, Chen said.
He said China's National Avian Influenza Reference Laboratory is soliciting support from relative authorities and is looking forward to production after clinical appraisal.
Japanese influenza expert Yoshihiro Kawaoka and immunology expert Xiaoning Xu have contributed to the research during the final stage.
http://news.xinhuanet.com/english/2009-05/02/content_11296882.htm
Close that deal!
Enough waiting already.
Today is was a great start
We closed at the high of the day. This is only the beginning. NO telling how high this will go. It started today.
Forget the Russell
The last time PPHM was added to the Russell, it hurt the stock price. You have all these funds or big investors that don't want to pay top dollar. If PPHM is added to the Russell it would have to be after the stock price triples. Who wants to buy a stock that has gone up in price so much. Hence, they will try to get the price knocked down before they buy it. Getting over a dollar with the R/S will get you screwed another way.
And then you have those who will try to buy the stock lower and sell it to the funds at a higher price. The bottom line, the professional stock market investors, aka shady characters, will get to manipulate the stock at the expense of guess who, us.
We have been here for years, believing in the product and so far being validated and all we can do watch as the Wall Street big players play with these stock at will.
The SEC is a joke. The stock market is rigged. Like you said, you have to know how the stock market operates and if you are savvy and disciplined enough, you can make money provided that you don't step on a mine put there to take you out by some crooked trader who is better armed than you.
Give my your opinion of this: the buy volume is disclosed real time while the short volume which almost always comes from the big players like hedge funds, PIPE dealers, and other similar shady entities, is disclosed every month or quarter. Then you have retail investors like jazzbeerman who update the short interest. By that time, it's useless. So, the shorters are allowed to short at will without alerting the retail investors that they are doing so. They can see your cards and you can't see theirs. This is the way the SEC was told to do it and they are obliging. How do you know you are not buying when some crooked or shady players is shorting with the added advantage of knowing things that you don't know?
Nobody ever says that not disclosing the short interest real time is major cheating. Every body accepts it as being part of investing in the stock market.
At least, our little company is being smarter than Martha Stewart when they can allow others to trade on insiders information without anybody ending up in jail, if that is what's going on here.
"In return of course, they have insight into news that will more or less guarantee a return."
That's called trading on insider's information with the complicity of our little company. Maybe, the retail guys, us, will ride their coattails. That's always the best we can hope.
MustBeFree,
So somebody is loading the truck under the radar. If I am right, you and others have been saying that this time it's different because somebody is painting the tape at the close and they are trying to keep this stock from falling back. Well, if somebody was loading the truck, wouldn't they want the stock to fall back so that they can buy shares at a cheaper price? Wouldn't keeping the price higher force them to pay a higher price? If they know about the blockbuster news, will it be such a bad thing when that news comes out and the price is 25 cents instead of 45 cents or higher? Actually, it would be better for them if the price is 25 cents when the big news hits.
I think it may nothing but just normal trading. We will probably never know.
I hope it works this time.
Like I said, they are big players that can do whatever they want with this stock. They can let it run for a while, make some money on the upside and then short it to make money on the downside. It has been clear for the last two or more years.
If it was all about the charts, then all I would have to do subscribe to http://stockcharts.com/def/servlet/SC.scan and retire.
The question is, what do you do now? You take a profit if you bought it at 29 cents and then watch it go over a dollar or hold and maybe it will go down again. Maybe you read MustBeFree when he said that he went heavily on margin and took a bath in some of his accounts. And he knows all about the charts and everything else.
Anyway, I need to have this thing to 1.30 to break even. It's very doable with everything going for this company but I cannot underestimate that some big player bastard can tank this stock at will.
Kgoodrich, I don't understand how all this chart analysis can mean anything when this stock is manipulated left and right. Whoever is controlling this stock can let the chart patterns develop and they they can slam it, shred it, uproot it, squash it, or do whatever they want with it. Has your chart analysis ever led the board readers to make a profit? Not if they were buying.
Goldfinger, you raised some very good questions.And I think you are right that this stock has and is being manipulated big time. We now know that the stock market is rigged and the retail investors which is us, are the ones who is being taken to the cleaners by the big players. And that's whether you invest in mutual funds or on your own. The big players do make big money and how can they make such big money if not by taking from the retail investors who are always kept in the dark? Whether it's Rodman & Renshaw, Melton, and the other PIPE dealer whose name I forget, UU I believe, they all came, made or are still making their money after seeing all the cards and we keep losing. I stopped investing in the stock market when I got fed up about two years ago. I still hope I can make my money back here or even make a profit. I think we retail investors are naive. Think about this: all buy volume is disclosed in real time. Short volume, which is done by the big players, whether they be the PIPE dealers or professional shorters is not disclosed in real time but only every so often, I believer monthly or quarterly. Why? So that the big players can short at will without alerting the retail investors that any minor or major shorting is underway. Think it about it. If the short volume was disclosed real time, we would have known every time Melton or Double U were shorting ahead of the PIPES. Instead, we were kept in the dark and they then they took the shares they shorted and they covered them with the lower priced shares they got when the PIPEs were consummated. And the fact that there was never any news to trip them up was no accident either. A guaranteed profit every time. And then, you had jazzbeerman updating the OUTDATED short volume. By the time we got the short volume updates, they could have shorted and covered several times and we would have never known. And we wasted out times readings all his scientific posts and short volume updates thinking that we were getting some valuable knowledge or advantage. But if you look at the shares price, we got the shaft every time. And this is just one way the big players take the naive retail investor to the cleaners. Wall Street is a place where all the rotten apples rise to the top. And then they hold all the cards and profit big time by victimizing the investing public.
They don't want the shareholders to be able to say anything because they don't care about them at all. I should have sold when I find out that they had to be forced to have CCs. At least I stopped buying about one year ago and have been saving my money in the bank. They have no regard at all for the retail shareholders and we are nothing but fodder to them. At this point, all I hope for is to make my money back. The BOD is using this excuse of a public company to enrich themselves and their cronies at our expense. What they have in mind we can only guess but it's definetely not our best interests. Maybe they want it all for themselves. That's my best guess. The stock market has become a place where thieves can come in and come up with all kinds of schemes to make money at the expense of the investing public. And the worst part, it's almost all legal. Invest at your own risk.
I guess lafont likes the punishment.
Or maybe is not invested in this at all and works for the other side. You have to remember that the BOD reneged on his promise to never have another PIPE and they have stated that the pps was going to take care of itself. Those are two recent promises that they reneged on. Add to that all the talk of being in talks that had to raise our expectations that there was going to be a real licensing deal and istead we got another PIPE. Or PL stating that AVID was going to raise all the cash needed something like two years ago? And how could they not know that this would keep people to stay with the company when they may had left then? When they made those promises and they never materialized you cannot sit there now and not hold them to what they said and promised. Or else, what's the point of saying anything at all?
Jazzman, help me understand...
We are supposed to get excited because the short shares are down again. They have been down for how many months now and it hasn't helped the pps a bit. The short shares report is proof, among other things that I can discuss if you so desire, that the stock market is stacked against the little sucker investor like us. I don't know if you fall in the same category as me or us. If they make the short shares public only once a month, then all the short players have to do is short the shares and cover before the next report and we wouldn't know how much shares had been shorted. If the benevolent and all good SEC and any other financial market regulatory agency, commission or what have you that is supposed to make the stock market so fair REALLY wanted to make the market fair, all they would have to do is make the short share public the minute they are shorted just like they do with the long shares. What would be wrong with that? Nothing, except that it wouldn't give the professional, big fish shorty such a huge advantage against the little investor so that they can make it easier for them to take the retail investor money. This is nothing more than one-way transparency which gives the big shorty player the big adavantage over the retail investor. It is just as fair as a one-way mirror which allows one party to hide and see everything without the party they are going against even knowing.
I will vote my 37,000 share against the reverse split. No to #3 and #4. This BOD cannot be trusted anymore. If all they want is the reverse split then the should reduce the authorized shares accordingly. If theyget the reverse split and keep all those authorized shares, then you know what they have in mind. Drive the pps down again and your shares aren't going to be worth anything when they do all those PIPES again. Anybody who says that the PPS will shoot up again based on news is a fool. That's what they said before. Whovever is controlling and shorting this stock must be in the know and close to the BOD. They must be working together.
Why all this rush to get an AIDS vaccine?
If you find a cure and give to those who have the HIV virus or AIDS, what's wrong with that? Are they working just on a vaccine or a cure?
Anybody saw this?
Something that gets a lot more publicity than the Bavi HIV/Hep human trial even before it starts its own human trials. Didn't Gendel say that the reason there is no news in the main stream media is because... I forget the lame excuse they gave. How come somebody who built a device to kill cancer gets to appear on 60 minutes even before they have human trials and Bavi/Cotara withe their incredible human trial results is always buried six feet under as far as the media is concerned?
http://www.fox11az.com/news/topstories/stories/NWkmsb20080730_hiv_breakt-hrough.1971ecbd.html
Doctors may have found a way to destroy HIV
10:16 AM MST on Wednesday, July 30, 2008
By Lee McGuire / KHOU-TV News
Video: Houston doctors may have found a way to destroy HIV
Larger screen E-mail this clip
[an error occurred while processing this directive]
HOUSTON -- There is real hope that what’s happening in a Houston lab might lead to a cure for HIV.
“We have found an innovative way to kill the virus by finding this small region of HIV that is unchangeable,” Dr. Sudhir Paul of the University of Texas Medical School at Houston said.
Dr. Paul and Dr. Miguel Escobar aren’t talking about just suppressing HIV – they’re talking about destroying it permanently by arming the immune system with a new weapon lab tests have shown to be effective.
Ford Stuart has been HIV positive for 15 years. He’s on a powerful drug cocktail that keeps the disease in check.
“I’m on four different medications. Three of them are brand new, and it’s the first time that I’ve ever been non-detectible,” Stuart said. “I’m down to about – just for the HIV – about nine pills per day, five in the morning and four at night.”
But Stuart knows HIV mutates, and eventually it will learn how to outsmart his medications.
“The virus is truly complex and has many tricks up its sleeve,” Paul said.
But Dr. Paul thinks he’s cracked a code.
“We’ve discovered the weak spot of HIV,” he said.
Paul and his team have zeroed in on a section of a key protein in HIV’s structure that does not mutate.
“The virus needs at least one constant region, and that is the essence of calling it the Achilles heel,” Paul said.
That Achilles heel is the doctors’ way in. They take advantage of it with something called an abzyme.
It’s naturally produced by people, like lupus patients. When they applied that abzyme to the HIV virus, it permanently disarmed it.
“What we already have in our hand are the abzymes that we could be infusing into the human subjects with HIV infection, essentially to move the virus,” Paul said.
Basically, their idea could be used to control the disease for people who already have it and prevent infection for those at risk.
The theory has held up in lab and animal testing. The next step is human trials.
Meanwhile, every day in Houston, three people are diagnosed with HIV.
The doctors still need funding to launch human trials. In the world of HIV research, that’s often where things fall apart.
“Clinical trials are very expensive,” Paul said.
“That is the worry of the researcher. This is what nightmares are made of – that after 30 years of work, you find it doesn’t work,” Paul said.
But so far, it is working.
“This is the holy grail of HIV research, to develop a preventative vaccine,” Paul said.
“If we can get the viral loads down to a manageable level, that will preclude the need for these conventional drugs,” Escobar said.
Still, even if everything goes well, it’s at least five years before the research could help people with HIV.
The doctors know people like Ford Stuart are waiting.
“There are so many people struggling with the disease because it affects not only your body, but also your psyche, how you perceive yourself,” he said.
If nothing else, the research is promising for the tens of millions waiting for a cure.
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"The logical conclusion is that we retail investors should hang on to our shares and make the same profit that otherwise would be made by "mgmt's new friends" (whoever they are)"
You're forgetting that many retail investors paid more than a dollar and the new managements friends would be paying a fraction of that. How would they make the same profit then? If you paid 30 cents you would be making 400 percent at 1.20. If you paid 1.20 ( which I did), you make nothing. At 3.60 you make 200 percent and the new management friends make 1200 percent. Who do you work for? Hopefully you don't have to do math. Maybe you work for management's friends. And you never heard of CINN either? They have only been mentioned 1000 times on this board when they were controlling the trading.
The shorts don't have to spread false rumors to sink this stock. CINN has been doing it at will without any false rumors. They can kill a rally and drive the pps lower whenever they want by controlling the trading and the SEC obviously doesn't care and lets them do as they please. The SEC has allowed the stock market to become a playground for the big players to suck the small investors in and take them to the cleaners. They may let you have your small gains but how much do you think the big players make at the expense of the small investors? So all the sudden the SEC has awaken when the Wall Street firms are being taken advantage of? Sounds funny, they only care when one of them is being taken advantage of. What about all those recommendations after the Wall Street firms and their clients have taken a position? Isn't that what a lot of people have said R&R will do when 'their time' is right? Aren't the Wall Street firms and the SEC, NASDAQ one and the same? Have we all the sudden become stupid or were we always that way?
Is the SEC A Joke and why isn't anybody suing?
According to the SEC,
"Manipulation is intentional conduct designed to deceive investors by controlling or artificially affecting the market for a security. Manipulation can involve a number of techniques to affect the supply of, or demand for, a stock. They include: spreading false or misleading information about a company; improperly limiting the number of publicly-available shares; or rigging quotes, prices or trades to create a false or deceptive picture of the demand for a security. Those who engage in manipulation are subject to various civil and criminal sanctions.
http://www.sec.gov/answers/tmanipul.htm
If the CINN and whoever is behind it has not controlled of affected the market for PPHM then no stock can ever be manipulated. Are the ones behind CINN subject to civil and criminal sanctions? Sounds like it. Every time there was good news, the stock would move up and the CINN would clamp down on any upward movement with their old, dirty tricks. They would sit on the bid and ask, move the stock with a few shares trade, have those ridiculous fractional bids. Not to be forgotten the 300 sh trade at the last second after the much bigger previous trades that got us kicked out the Russel and started the biggest slide. Any trader would just walk away knowing that he could not make any money trading PPHM. How about a good old fashioned lawsuit with the law on our side and obvious damages inflicted on the stockholders and the company with a stock price that has been driven to the ground even with really good news?
And for good measure, the NASDAQ can be sued too for allowing all this illegal trading. Does anybody think that NASDAQ advertises that this kind of blatant and criminal manipulation would be allowed on your stock when you are deciding whether to trade on the NASDAQ?
And if the SEC does not enforce its own rules when it has been alerted, shouldn't they be sued too? Don't people sue and win for much less and don't we have proof of manipulation and damages to show for?
http://sec.gov/answers/tmanipul.htm
Was the PR on Saturday rather than Friday a good move?
Probably. When PPHM was included in the Russell two years ago, we got no pps appreciation at all. Maybe a loss. You saw some thirty million shares change hands in a few minutes if I remember correctly and no boost.
Read this:
"The managers of all those funds will have to adjust their holdings to follow the new lineup in the indexes. But before that happens, hedge funds and others will try to take advantage of the changes.
"Hedge funds are going to try to game this," Calvasina said. "To a certain extent it's already been happening."
The last thing you need is the hedge funds playing with this stock while you are trying to get it over one dollar. No thanks. Been there. Done that.
http://biz.yahoo.com/ap/080531/wall_main.html
It is kind of naive
to think that all you have to do is look at the science and everything will work out in the end. That may be true in a world where there is no greed, deceit and getting ahead at the expense of others (the retail investors being the others here).
If there is any money to be made here, the retail investors will make the least or even lose after the insiders and heavy players with inside knowledge and ability to manipulate and control the trading and pps are done. You have to wonder how somebody who is so scientifically minded could be so totally oblivious to the business/investing side of this stock or any stock. Could there be even a slight chance that we are being taken for a ride?
Volgoat,
thanks for simplifying it for us. All you have to do is look at what happened at another biotech and we can deduct that the same thing will happen with pphm. If that was true, imagine how easy it would be to make money in stocks. Of course, Immunex did not have a BOD as unfriendly and incompetent as what we got stuck with or did they?
"Something is going on and the BOD don't want to talk about it yet."
It was going to be an interview. You don't have to talk about anything you don't want the public to know during an interview, like anything that has to do with an impending deal or trial results. But you can still talk about a lot of other things. The fact is, they turned down an opportunity to get the company some free publicity. You have to ask what company would do that? Maybe companies that don't have anything they can be proud of? Maybe they are still not done with getting all they can for themselves and their 'friendly' financiers.This might explain why we have never seen an article anywhere. Just look at the 60 minutes piece on a guy who build a radio waves device in his garage to kill cancer. Now ask yourself if Thorpe' story is not any better than that. Do you think PPHM could get this kind of publicity if they even asked for it? Didn't people who attended the shareholders meeting report that ES didn't look to o happy and rather sickly? There must be things going on that they don't want us to know. Maybe we can get Kevin Trudeau to write a book titled Cancer Cures PPHM Doesn't Want You To Know.
"And Peregrine Pharmaceuticals Inc. of Tustin is working on cancer development drugs. Peregrine officials declined an interview request."
It looks like the local business paper cares more about the PPHM story than the BOD/management team. Obviously, they have nothing to be proud of that they could talk about. Remember, they had to be forced to hold CCs. It looks like that whatever they are doing or not doing, they want to keep it a secret. I guess that says a lot about how much they care about the shareholders or maybe even bringing the drugs to market. Hopefully, we get to ride they tailcoats if things pan out. Don't know how much more patience it will take.
"They will try to get it over a dollar to avoid delisting"
Let's not forget that they tried to get us back into the Russell with the Dios PR. But then someone tried to prevent that and succeeded with a 300 share trade at the last possible second which nullified all those big trades during the last few minutes. The high fives among the retail investors didn't last too long. What else are those who have it in for this company in store to get the company delisted no matter what the BOD might do?
The last thing you would want is the Index Funds trying to get a low pps if pphm gets added to the Russell at the same time that pphm is trying to keep the pps above 1 for ten consecutive days. Maybe it might be in their best interest to see the delisting issue go away but you can be sure that they are going to do whatever is best for them. Like you said, we cannot forget the 300 share trade that got us of the Russell. You are dealing with some players who will do whatever it takes to make money even if it means destroying the company. Of course we are always in the dark. We don't know what role if any the BOD has played in all of this manipulation. One thing we can be sure of is that if we ever find out who or how this company was manipulated, it will be too late for the retail investor. Think about it. How do the hedge funds and other sharks make money? They do so by sucking in retail investors, taking them for a ride and then taking their money. They can drive any small, struggling company into the ground if that's what they have to do profit the most. Isn't that what Cramer has been saying lately? Retail investors are at the mercy of someone who is trying to make all the money they can and we are being outgunned and will not get any help from the SEC and Nasdaq when rules are blatantly being violated. Without being able to sue since there will be nothing left. That's the worst scenario. I hope it never happens. It always seems that the worst possible thing keeps happening for this company. The PIPE after the end of PIPES, the 40 mil govt grant that never was because of the cutback, the delay in the Dukes publication of Bavi' role in their research might mean we never get anything out of Duke. They sure know how to get all these fires going to keep you hoping and waiting but nothing ever happens. Let's not forget what happened to the Bavi Hep C trial. Going no where now.
Somebody still thinks that getting into the Russell
is going to help the pps? What happened the last time PPHM was added to the Russell? Didn't the pps tank? You really think that once pphm is added to the Russell there is going to be a stampede by the index funds to buy pphm? Or are they going to pay less than whatever the current pps will be at that time like what happened the last time pphm was added to the Russell thanks to their friends in high places? We're supposed to forget the games that were played the last time. I sure hope that all of the other events that you listed pan out a lot better than being added to the Russell because if not, we will be in even deeper trouble.
"And let's not forget that the Russell rebalancing cutoff is May 30.
Best wishes and IMO.
KT "