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On this we can agree. I didn't like it 2 years ago and said so then. I don't like it now. Usually a VERY BIG red flag. Having said that, I have no choice (in my mind) but to hold and hope.
I am in way too deep to sell at a large loss. Would rather stick it out and lose it all.
Thank You, I guess any press is good press? ... BUT we went through this kind of thing a couple of years ago with ex-CEO PH and MRKR ... it does not look good to have to PAY money to a "Hype the Company" outfit. I think last time it was Redchip or somelike like that, this time it's Proactive.
If you Got the Goods or if your press info was relevant enough, it would be disseminated by "normal" news outlets, you would NOT have to PAY for your information to be published.
In general, companies that Pay for Hype are garbage companies and they know it.
Honestly, your asinine replies are getting tiresome. You make a statement like "They should've forgone the rs and brought in a partner with cash." without the slightest level of deeper thinking.
Examine your statement, "They should've forgone the rs". Anybody with a functioning brain realizes that IF they "forgone the rs" they would have been delisted by Nasdaq.
WOULD THAT HAVE BEEN BETTER FOR THE COMPANY AND SHAREHOLDERS?
Yes or No.
"and brought in a partner with cash." Us adults that live in the real world understand that in real life (not the fairytale make believe world you seem to live in) you don't get to just snap your fingers and make a cash partner just appear. If there was none to be had, then there was none to be had, PERIOD.
Before you go on your next ludicrous rant, WHATEVER reasons there was none to be had, those reasons are IRRELEVANT.
They could find no "cash partner", they did not want to be delisted (DUH) so they HAD NO CHOICE but to do a R/S.
After I click "Submit" I will return you to the IGNORE status so I don't have to waste my time reading childish gibberish.
"What Marker needs to do is show that it works." 100% True.
"The restructuring gave them as good of a shot as any to figure this situation out. It was a very good move." Also 100% True.
Now, we wait and see.
Thanks.
ONCE AGAIN, THANK YOU. "It's obviously a long shot but given how cheap Marker's therapy is to produce, the low bar for approval (IMO), and the CR we saw in the PI I think it at least warrants further exploration. The more shots on goal the better."
After reading that, I think I would agree.
You know, speaking of MRKR and MRKR stock, I am reminded of an old saying.
I like old sayings because if they were not true, they would not stick around and be retold for many many generations.
"It is better to keep your mouth shut and be thought a fool, than to open it and remove all doubt."
GO MARKER
If it is not an AI Chatbot programed intentionally to be argumentative and obnoxious, then we should give it an award because it does one heck of a job at it.
Whether "there's likely subtleties" or not is 100% IRRELEVANT because ...........
AGAIN, for the SECOND TIME ........ and perhaps it will read and comprehend this:
"EVERY SINGLE large firm that currently holds MRKR HAS been HOLDING MRKR for many quarters ALREADY when MRKR was WELL BELOW $5 ALREADY. MRKR was and had been BELOW $5 for a long time before the reverse split, Sooooo Mr. can't figure out the obvious for yourself, IF IF IF those institutions you imply won't be allowed to hold MRKR because it is below $5, then it is OBVIOUS that they would NOT have been allowed to hold MRKR in the past, WHICH THEY DID. DUH!."
SO, EVEN IF there ARE "subtitles", they would NOT have been allowed to hold MRKR in the past ......... and THEY DID.
Howdy Phantom, Please don't spend time doing research on this question, I'm not looking for an exact answer, just looking for your general opinion which I know from reading your posts for years you already have this info pretty close in your head.
In the past, when I questioned why a psoriasis company was worth so much more than a AML cancer company in roughly the same stage of development ... your lesson was ... SIZE OF THE MARKET .... which of course makes sense.
So, my question (or actually two part questions) is/are this:
IF AML market size is a 1 and psoriasis market size is a 10, can you give a rough estimate of what number the lymphoma market size would be?
Also, same question for pancreatic market?
This is the part two part: You have said many times in the past that AML Active was difficult indication to go after ... and you have said that pancreatic was also a difficult indication to go after, so, based on your number for the pancreatic market from the above question, and based on the Difficulty of pancreatic, do you think (even if they somehow are successful) that it is worth spending more money on pancreatic when AML Adjuvant and Lymphoma are futher along and may be a better market size?
I guess I can sum it up by asking, is MRKR trying to make money (profits) or are they trying to be altruistic even if the market size (and potential profits) are small?
Thank You
Concerning this being allowed to buy below a $5 price.
Yes, some institutions and mutual funds have their own rules in their prospectus about buying limitations.
Some stay away from low dollar prices to avoid being too close to the threshold for being delisted (just to give themselves more comfortable breathing room).
Some stay away because they want a Much Larger potential bandwagon of buyers buying right along with them in order to keep the share price high and going up, and THEY KNOW that MOST of the investment community money GOES TO above $5 stocks, and therefore there will be MUCH LESS potential for investment community money to go into the cheaper stock to drive the price up.
MOST stay away from penny stocks or anything near that. That's nothing new.
BUT, this statement of: "The firms holding Marker have rules so we'll see the next quarter or two if they have the $5 rule." , is absolutely ludicrous (no surprise) because all you have to do is THINK.
EVERY SINGLE large firm that currently holds MRKR HAS been HOLDING MRKR for many quarters ALREADY when MRKR was WELL BELOW $5 ALREADY. MRKR was and had been BELOW $5 for a long time before the reverse split, Sooooo Mr. can't figure out the obvious for yourself, IF IF IF those institutions you imply won't be allowed to hold MRKR because it is below $5, then it is OBVIOUS that they would NOT have been allowed to hold MRKR in the past, WHICH THEY DID. DUH!.
OH MY GOD - How MANY times must we (me - you - others) answer the SAME DAMN QUESTION?
Question: So why the reverse split then?
Answered MANY times: To avoid delisting from the Nasdaq (it's F...ing OBVIOUS).
Hello GMA13, After you go to the website you gave me, after you scroll down, find #1 NEA, go to the right side and click on "History".
You will see they held those same shares for a long time.
They went from holding 10,714,285 shares going back to 2021Q1 to holding 1,071,428 after the reverse split.
It is the same for all of them. I think they are just calling them "new" holders because they are holders after the "new" share structure post split.
Nea and Aisling and others have been with us for a long time now.
according to nasdaq.com, https://www.nasdaq.com/market-activity/stocks/mrkr/institutional-holdings , there are only 2 "new" positions, all the other have held those same amount of shares for many months.
New and Sold Out Positions (at last reporting 3/31/23)
ACTIVE POSITIONS HOLDERS SHARES
New Positions - 2 holders - 58,306 shares
Sold Out Positions - 18 holders - 43,161 shares
58,306 New Total Shares Held
AR ASSET MANAGEMENT INC 03/31/2023 40,700
SUSQUEHANNA INTERNATIONAL GROUP, LLP 03/31/2023 17,606
There were 43,161 shares sold by 18 holders and 58,306 bought by new holders.
I am beginning to think it is an AI Chatbot programed intentionally to be argumentative and obnoxious.
Short shares up from 9,000 before CEO news to now at 218,000. Buy on the rumor, SELL on the news. The slow trickle down continues in the absence of positive trial data. The news void ahead may well trickle us down below $1 again. Then what? Maybe I'll add below 75 cents if we see it.
Thank You for all the info.
If RNAI + MRNA + CRISPR + CAR-T are the news kids on the block and they start having more and more success, then Markers Multi-TAA must rely on the advantages that it has. #1, much quicker to produce. #2, much cheaper to produce. #3 no cytokine release syndrome (so far).
I think even with those advantages, when the doctor and patient are discussing potential treatment plans, unless Marker can show a success rate at least somewhat comparable to the new kids, not so sure many will choose quicker and cheaper when it's their life on the line.
A vaccine for pancreatic cancer. 50% success rate. BioNTech using MRNA.
https://www.msn.com/en-us/news/other/finally-a-vaccine-for-one-of-the-deadliest-forms-of-cancer/ar-AA1b1vc2?ocid=msedgdhp&pc=U531&cvid=8ebce6c5041042c198180ae3b71cf483&ei=43
Thank you for using facts and logic and reason in your post.
If only the poster you responded to would at least TRY to do the same.
The problem is most conspiracy theories are devoid of any of those.
Maybe Marker should of went in to plant medicine. Even less sexy than veterinarian care.
P.S. I hope you got that post # 33503 was a sarcastic spoof ... but I'm not sure if anyone made the styrofoam cup connection with Dart.
He is like a young child who learned to play with simple square blocks. The problem is, he has not advanced and progressed from there. He can STILL only function playing with simple square blocks. Blocks that have logic and reason and understanding are completely meaningless if they can not be processed.
If a tree falls in the forest - and there IS someone in the forest - but that someone is TOO DENSE to hear it - does the tree make a sound?
I bought prior to the deal at $1.11, have not any bought since. Will buy more when it goes below $1.11 again (which it may over time with the long wait on news and no data coming soon).
You are just talking to the wind that can't hear. What did Shakespeare say in Macbeth ...
LC constant yapping is like "It is a tale, told by an idiot, full of sound and fury. Signifying nothing."
At this point, anything that works is fine by me. I know Wilson and Vera know a lot more than me. All I can do is look over their shoulder and second guess with the benefit of hindsight.
As of 11:20 we're up 13 cents (we got a new CMO). That's nice but meaningless. Less than 40,000 share volume is about $60,000 dollars buying shares, next to nothing. Need to go up on much larger volume, day after day after day. I kind of doubt it. Would love to see it, but I don't know.
Well, we will wait and see how Monic Stuart works out as the new CMO. Been reading up on her.
On one hand, previous to Marker she was at Geron who after 33 years MAY POSSIBLY get their first drug approved in 2024 (myelodysplastic syndrome MDS). Previous to that she was at Genentech and let's be honest, anything done with Genetech back then was caveman technology compared to current tech (RNAI, MRNA, CRISPR, CAR-T). I think Marker may want her more for FDA regulatory huddles and trials advancement than having her figuring out which new antigens to add to what compound mix.
On the other hand, as per Juan Vera: "Given Marker’s prioritization of the clinical program in acute myeloid leukemia (AML) and lymphoma, bringing on a CMO who is a transplant physician and has extensive experience in treating AML and lymphoma patients is a tremendous advantage in establishing our clinical strategy. Dr. Stuart’s impressive career both in industry and in the clinic as a treating physician will be key to enabling Marker to identify the optimal paths for advancing our programs targeting hematologic and solid tumors."
Let's hope he right.
Phantom has also said the pancreatic cancer is another tough nut to crack. MRKR seems to want to go after the hard cases to help or cure. If the early adjuvant AML data gets just a bit better with time, we may be sitting good for future returns, which will almost be as good as helping the patients.
Marker Therapeutics Appoints Monic Stuart, M.D., as Chief Medical Officer
Trends tend to turn out to be FACTS a lot of the time. The old saying, "the trend is your friend". When you observe and learn from history, you will not make the same mistakes.
What has happend with MRKR for the last year is no suprise at all. If fact, what has played out has been posted on this board, in advance, many times (Phantom said many times that Active AML was a tough nut to crack and he was concerned with financing/cash burn rate/trial delays etc).
Advise given on this board on 12-29-22 when share price was 24 cents (equivalent to $2.40 post RS) was "a reverse split is happening very soon and after the RS that new share price with Drop Down Further, so you might be better off waiting until after the RS to get a better price on a per share basis."
Posted on 2-11-23 to a question of "when to buy", answer was "After a 60+% pull back from the RS. Below $1.50, That's what I'm waiting for. Without great news which is not coming anytime soon, it will be a slow trickle down in price."
Well, after the RS, we went down to 1/3 of that $2.40 and are now at about 1/2 of that $2.40.
Here's a FACT, most times with a tiny company, when they do a RS, the short sellers smell blood and pile in. It is almost never fully "factored in to the PPS" before the RS, and most times after a RS it CONTINUES TO GO DOWN FURTHER.
Well, we got some good news with the Vera/Wilson deal and the share price went up a bit.
And a good chunk of it was day traders smelling quick in and out and in and out profits.
And over time they fade away and move on to the next target.
We now have financing through 2024 at least so for now, Financing no longer an issue, which was NOT the case at all in Dec. 2022.
But we also have a potential data/news desert for the rest of 2023 and most of 2024 until adjuvant AML news.
What will happen to share price till then? No day traders to prop it up. A few shorts might come back to try to earn their pennies.
Many traders go with another old saying "buy on the rumor, sell on the news".
As far as MRKR, I'm not a trader, just a holder, was never much for the strategy of "buy higher before the RS, sell lower after the price drops even further post RS as expected".
My last MRKR buy as posted was at $1.11 on 3-23-2023, post RS as the price tumbled down still futher as expected.
So where does the price go from here? In the absence of any good news, history would tell me downward trickle over time.
I hope we can hold above $1.
I would love to hear Vera give us a somewhat ACCURATE estimate on when will can MAYBE expect some adjuvant AML data/news.
I think that will hold more weight than any preliminary early lymphoma or pancreatic news.
We had the Kentucky Derby ran this past weekend. Now that PH is GONE as CEO, (THANK YOU), MRKR reminds me of another old saying about thoroughbred horses, "breed the best to the best and hope for the best".
GOOD LUCK TO ALL.
Very Well said, but it will go in one ear and out the other ............. UNLESSSSS ........ wait a second now .......... MAYBE now YOU are part of the conspiracy ......... yes that's it ...... it's Wilson and Dart and Vera and You and Phantom ...... you all are part of it ....... I see it now ....... and you all are getting kickbacks of free styrofoam cups ....... yes that must be it.
You see the beauty of it? If the exposed conspiracy is presented on purpose to be so utterly ridiculous that only a true dullard moron would believe it ....... then that's makes the perfect cover for it. WOW it's so clear now ..... the brilliance of a set up total scam hatched by a styrofoam cup and THANKFULLY exposed to all of us by the careful consideration and precise thoughtfulness equal to that of a styrofoam cup.
DAMN THOSE STYROFOAM CUPS.
I am glad that we FINALLY found out the REAL reason for the reverse split.
We have now been informed that the real reason was for OPTICS.
It was not to keep from being delisted on Nasdaq, OHHHHHH NOOOOOOOOOO, it was solely for OPTICS.
Very relieved now that that has been cleared up.
BTW, anybody want to buy some ocean view property in Iowa.
"Done with this nonsense…" --------- Yep, best way to deal with a couple of posters here.
"I hope he (John Wilson) knows what he's doing." MEEEE TOOOOO.
"So, totaling all of the numbers up they have spent ~$17.3M on the manufacturing facilities. I think it's fair to just call it a wash on Marker's end but Wilson definitely didn't come away with assets purchased below cost.' It's easy for people to argue when they don't use facts.
Once again, Thanks for the info and facts.
Mr. John Wilson stated: "The reality is that Marker has not yet met our investors’ expectations."
and he wins the understatement of the year award.
Ok, he gets one year salary (TOO MUCH but it is what it is) and COBRA insurance cost is not expensive at all. Turn the page and hope the next chapter is much better. Thanks
Let's hope he doesn't get a 10 million dollar buy out bonus as he heads out the door.
Thank You
"confidence, maybe overconfidence". Yep, just like the rest of us. Oh well, we're all in this boat together .... well, those who are left anyway.
and it appears like you were 100% correct. I had said here in the middle of 2022 and near the end of 2022 that if they did a RS, the share price would continue to do down quite a bit (as happens 98% of the time), but my personality is just too stubborn to sell at a loss.
That might explain why "others" bought in ... they were as stupid as the rest of us, but I wanted to know why "the company insiders like PH" bought in at $1.75. They didn't fool themselves with talk and presentations.