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About piglet OTCX according to OTC pig mom: [piglets octx and jane have spearheaded the current round of price manipulation for a while]
"The OTC Link ECN expands the depth of liquidity in OTC Securities by combining the Broker Dealer Network model with Anonymous, Auto-Execution functionality.
Access Greater Liquidity: Over 80% of non-internalized volume in OTC Securities occurs between OTC Link ATS subscribers
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OTC Link ECN's aggregated top of book will be integrated with OTC Link ATS
Electronic order book functionality is provided by a low latency matching engine
Limit order book will include support for reserve orders
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Maker-Taker Pricing Model
Anti-internalization capabilities
https://www.otcmarkets.com/otc-link/otc-link-ecn
Piglets otcx and jane are on it again manipulating absence of news on the backdrop of cvm failure
They have been on it for quite some time, which stimulates me adding more shares.
Dave Innes efforts to persuade funds (particularly family funds)to be onboard have mostly failed so far, but things could change in a lightening speed for these funds which are currently on the sideline waiting for "de-risking" despite that kind of de-risking has been existing ever since 2018 publication and knowledge of how GBM has been treated and the decades-stagnation of treatment outcomes.
I can smell the taste of those piglets being roasted!
NWBio's P3 trial of DCVax-L for GBM has met its primary and secondary endpoints. The company has consulted with FDA and is seeking FDA's approval of DCVax-L for both nGBM and rGBM -- it will come, and may come any day!
I like roasted piglets
Not really. Short-term (a few days) impact of the failure of cvm on nwbo price - everybody has seen it now
med-term (within week) impact -- favorable for nwbo price appreciation
Long-term impact - none
only explain the first one - sympathy price drop understandable as most investors particularly non-investors who are considering and about to take a position are ignorant and have not done their DD yet. after some digging and digesting, actually those undecided or those who may be panic and sold some shares will finally realize
1) Multikine and DCVax-L are actually two different beasts
2) NWBio will be most likely meeting its primary and key secondary endpoints
3) the worst scenario for nwbo price drop if ever it would fail in its trial not meeting its primary endpoint like CVM is in the worst case 40%, not really that much expected by most investors
As a matter of fact, NWBio will probably meet its primary and key secondary endpoints
[conclusion:} new blood will flow into nwbo within days]
There is a huge and fundamental difference between cvm and nwbo in terms of MOA of cvm's failed Multikine and nwbo's dcvax-L.
Multikine is an immune booster designed to boost a patient's immune system before SOC treatment aimed to improve OS, quality of life, etc. just like grandma's chicken soup, while DCVax-L is not only an immune booster but more importantly "a cancer killing machine/system" loaded with patients' specific antigens, designed to seek, find and kill cancer cells.
CVM: CEO has constantly pumped the stock via social media and shareholder letters; the slim advantages (10% better than SOC) designed being very consistent to repeated failed previous trials for other indications (so aimed and fine-tuned to achieve "a lucky" success); one week before TLD a huge financing.
NWBO, CEO has behaved completely differently.
You buy nwbo -- a winning strategy
Don't touch cvm yet -- a winning strategy
[and Linda is dare enough to have dcvax trial results reviewed and analyzed by a panel of independent GBM experts!!!!]
[so the otcx pig is still on this one as of 9:38am 29 June]
agree, agree and agree
last post for me today, going to buy more if continual drifting low; already bought a lot at 1.50-1.52 range
GLA! we are close, very close
I can guarantee you the headline of nwbo's tld is nwbo's dcvax-L trial has met its primary endpoint
versus cvm's which avoided saying it has failed its primary endpoint, instead, cherry pick a subset.
logout and focus on buying more shares
CVM's failure is expected by many. The agent they tried Multikine has failed many times before for other cancer indication.
Despite its general failure for head and neck cancer, I do believe after all have settled down, they should get Multikine approved for those patients who receive Multikine followed by the part of SOC (surgery and radiotherapy only without chemo) because of reasonable improvement of OS plus quality of life for patients.
As for NWBO's DCVax-L, it's the first time DCVax-L is used in p3 clinical trial built up from positive p1/2 trial;
Most importantly, we know what the results would be look like from interim blinded, blended data published in 2018 on the backdrop of no improvement of SOC for GMB for decades and improvement data uptrend observed from the followed up data presentation after the publication.
Unless the final data readout is significantly worse than the data published in 2018 and/or placebo patients (or patients who received vaccine later after progression) outlive patients of treatment arm (or patients who received vaccine earlier before progression), it's no way DCVax-L will not show significant efficacy over SOC.
As I am typing, my first buy order is shown filled at 1.52. Intended to buy more as the price is artificially pulled down for obvious reason today: psychological impact for those ignorant due to CVM's failure, despite there is nothing comparable.
Besides, cvm ceo has spared no opportunities in pumping cvm stock while our dear ceo Linda has spared no opportunities keeping quiet.
[got a tiny order filled again at 1.51 as of 10:48am]
[Plus, cvm's large financing just last week or so was very suspicious]
[got this batch of order filled at 1.50]
[more to come]
Agreed, thank you and good luck to you too.
Not really. First, I for one believe there have been a naked short wolfpack who is one permanent force against this company and our collective interests;
Second, periodically, there are forces (not the same at one time) who want cheap shares and they will resort to bashing, FUD, etc.; and
Third, Market makers make money by making the market. Often than not, they would bring the price down, and accumulate which is the nature of market makers. So when a company openly say it is in a quiet period, it's a signal to market makers to bring down price.
At least, Linda has not committed a specific timeline which is desperately wanted by manipulators more than long-term investors.
At some time, these forces above act either coincidentally or not, results in depressed share price.
If you would ask me, when is the best time to buy or add more, I would say its when people are desperate and see no light ahead (in the near future) just like know.
years old. clue "in over 80% of the patients who have received DCVax in clinical trials to date"
Before data lock, around 90% of the patients had received DCVax in the clinical trials
There are always buyers who scooped up any shares sold. I am a buyer at $1.6s, $1.5s, and now you bet.
Initially want to sell some [other] stocks so that I can buy more here but the last minute I decided to take some money off my personal line of credit (byw at rates of around 2% -- kind of free money).
Here you go I am a buyer!
i will venture to say the company will release TLD as soon as it is ready, meaning the company may not time the release intentionally (as we believed in the past) to be close to publication/conference presentation and/or manufacturing certification.
the reason is that if the company has really been going through the process outlined in 5 October news release, which seems to be the case by now since the company has stressed it in the news release later and in accordance with what Linda has said at annual shareholder meeting.
In this sense, it seems the company will actually follow the conventional route of releasing TLD, followed by conference and publication.
Those six steps of process outlined in 5 October release, if followed through, will definitely guarantee high quality analyses of data and results, which will be proof against the usual nonsense, naysayers and innuendos.
So the time of TLD could really be any day from now, probably in July, followed by presentation of detailed results in ESMO in September.
Oh Danish Dude not that one. It looks innocent.
Pig OTCX along with other piglets like Jane have successfully brought the share price down a penny or two for many days now.
And I have also successfully tagged the pigs and added shares which will be shares taken out from market so that pigs have to pay higher when they have to buy.
Pigs understand DCVax-L will be approved and made commercially available and TLD may be just around corner, despite a big than usual corner.
Yes, pigs are pigs. Have you ever seen a pig smile?
Take the advantage of pigs fatal defect, and buy as many shares as you can afford at this range!
you bet Doc
Based on what you have said and believe as a long-term investor, I would suggest you to close your position.
My understanding of the trial taking this long and yet to be announced with TLD is simply this trial has lasted almost 12 years. It's wise to get as detail as possible of each participated patent data so that a whole and representative picture of the trial will be represented by the data that has nothing to be doubtful and missing.
I am quite confident DCVax-L will be approved for the whole nGMB population. The delay besides for the reason of getting every possible data piece of every patient in the unprecedented Covid-19 pandemic situation may be also due to the serious discussion for the approval for rGBM.
I have stated repeatedly I am a big believer and I have continued to add to my already, unprecedented large position (I have never concentrated so large a position in my decades of investment in stock market).
For that, I pray to God, please help me for my selfish large investment and please give future patients a safe and efficacious treatment!
Obviously this round of price raid has been spearheaded by market maker OCTX (OTC Link ECN)which must have been contracted to do what it has been doing for a while.
I am watching its action closely so that I can decide how much money I should put into work this time, although I suspect it's highly likely the action is in preparation for a substantial share purchases, either short covering or share accumulation.
As a result of this partly, I have increased my net almost daily.
Nothing of these micro-analysis or tea leave matters much actually as I believe the vaccine will be approved and commercially available and the price will be much higher of from multiple fold to ten fold shortly after TLD.
Pity it's not in the interest of the company at this time to correct the share price by paying attention to the market, which is understandably as they have worked hard to bring TLD/publication into fruition at an appropriate time.
yes and I am also interested in other kind of manipulators who would short sell first via platform such as OTC Link ECN anonymously, followed by sneaky accumulation of shares.
IN this time of quietness and closeness to TLD, those who want shares are more likely behind the current manipulation, in cahoots with wolfpack naked short.
Both of these groups are pigs because they ignore fundamentals and long-term health of this investment for own greedy selfish needs.
There are always people who are fine to enjoy looted and stolen money, despite their relative large charity existence.
They are pigs in nature.
You can always find something you want from the chart. At least it can kill some time and feel good if guess/charting/TA is right.
Those pigs who manipulating the price are not following the chart. They follow pig heads' instruction at a time of quietness.
Like a few un-invested in this board need just to fud with no intelligence at all. There is always money to make to get by.
They are sneaky and patient and opportunistic in doing their jobs.
Fortunately we are better at this game to play long, 'cause the results are on our side!
marzan, according to https://www.otcmarkets.com/otc-link/otc-link-ecn
It does seem the structure of oct link ecn makes it a perfect hiding place for manipulators at OTC market.
But for what we have known about the trial and I think these manipulators as well, the action they have taken today to suppress share price is meant to have a covering price low and/or accumulation at low price.
They may have some fun for a while, but I hope when TLD is announced we can all make a pledge not to sell a share for at least a number of days.
Then, that would be a very beautiful revenge and a wonderful rewarding process seeing the share price go to the moon!
this is my last post for today. GL my friend.
You are right why we have only had "legacy" funds which have participated in financing over the years. Those funds are called vulture funds.
Nonetheless the same reason why Linda was willing to see the share price dive into teens as today when a self-imposed quiet period is in effect seeing share price hovering in a suppressed range such as around $1.5.
In the past when share price was in teens, she and her associates had been able to reward themselves with warrants and options at outrageously low price;
Today she and her gangs will still be able to do the same when NWBio hits milestone such as TLD when they will be rewarded with options at unfairly suppressed share price as well.
Hence, taking the advantage is the only way to balance her acts and market manipulation, which is buy shares at proportionally suppressed price.
Note, the above practice is nothing illegal. I am no complainer simply I have been a buyer at cost of manipulators, for the day is getting closer when I can count my chickens or laugh all the way to banks.
As usual pigs are working on share price in protect of Linda's endless quiet period. LOL.
A big enough sized fund has not yet been onboard, despite DI has been in his position for a long time.
All other funds like the island boy clubs, or bigger C and the like are just an opportunistic bunch, simply lack of resources and conviction,
which means share price has been depressed multiple fold more than a similar company which is subjected to manipulation and naked short attacks.
That's why I am a buyer in this range of share price, for ultimately this one will change the world of cancer treatment around the world.
Thanks marzan always for your steadfast support and great insights. You are one of the reasons I am daring "recklessly" in buying lows.
Hope you minions still have dry powder to put some more nails into the manipulators, and let them feel more pains in the process of manipulation.
Good advise for trading with core share base intact. However, for most people it's actually a dangerous practice:
A pattern intentionally made by MMs/short seller/anyone who wants to manipulate for accumulation or all of the above, would form, usually with a few pennies of difference or profit margin for trader. when the pattern is noticed by most traders, with some already successfully traded with a few or a couple of pennies of profit and increasing become bellicose, the pattern would usually be broke.
Most time, without news the sp would suddenly drop below the band of the previous pattern, and trust me most people would be caught off guard.
So my usual approach is to accumulate in waves, if necessary I would resort to other means to get to the bottom price, such as liquidate a property and buy cheap shares (rarely happens that way).
This one will bring a huge reward to those who have been persistent and daring.
For changed regulatory dynamic, market euphoria, high odds of significance in both primary and secondary endpoints, highly unmet needs for new treatment, etc.
As I am writing this, I got a popup message telling me my order has been filled.
Great and thanks for MMs
You said, " I understand that there's always a risk associated with investing in pre-revenue biotechs and as such, we should all have de-risked our investment at this point by recovering some, if not all, of our initial investments in NWBO"
Not me at this price, instead I added and added and added at this price. I blame Linda to not release trial data yet for my crazy action of adding or I should say average up "endlessly" at low sp.
I will only become a reduced/de-risk net share count holder when the price is much higher.
I do think the sp should be at around $3 before TLD based on my DD on the high odds of success of the trial for at least nGBM if not also for rGBM; the sp should be around that area also because the current market which is flooded with liquidity, even teens or college kids having been investing who are mostly high risk takers.
Anytime the next wave of sp running up will be here, from lone significant buyer, or shorts who sense it's time to cover after they or MMs surpress sp for enough time, or any positive news (not necessarily TLD) from the company, or simply technically it's time to run it up from MMs.
I have focused my recent buys at this range for a while.
To put it in the relative perspective, nobody knows how it works NVCR persistently has a market cap of well over 20 billion, while GBM P3 failed, presently only three P1/1b trials ongoing CLDX has fetched a 1.2 billion market cap.
What we stands today? NWBio from what we have known today would soon confirm its P3 trial for GBM would be significant in both the primary and key secondary endpoints, and it has a significant patent portfolio in the protect of its DCVax platform which could deal with both all operable and inoperable cancers, plus some positive P1/1b data indicating great potentials of the platform for various inoperable solid cancers.
And we stand today at slightly over 1.3 billion.
In today's market where each and every assets are significantly inflated in a bubble about to burst situation, it would be very conservative NWBio should be rewarded with a market cap of at least 3 billion before the big revelation.
I did feel buying shares today at around $1.56 is like buying shares early last year at about $0.18.
Today's buying in the range around $1.54 - $1.57 feels like buying in the range of $0.15-$0.19 early last year.
The difference is we are more than one year further toward the revelation we all have anticipated.
Trying to release some more dry powder in case it further bottoms today.
So far so good making use of stupid manipulators. Now it's pure technical buying in the low.
To add to my laboring: who chose that panel of independent experts? If it is NWBio or its consultants, it shall not be called independent.
It must be a third party, and who would be the most qualified third party to define and choose "A PANEL OF INDEPENDENT EXPERTS" for the purpose of independently reviewing and analyzing DCVax_L P3 data for GBM?
I cannot come up with anyone except for a concerned RA such as FDA.
So when the next news comes, it may be TLD or actually an approval of sort.
Yes, to be approved, NWBio should first submit BLA, but how about an approval conditioned on formal BLA submission and review.
I know data is ready, manufacturing process is being certified. What else?
Not that high figures. Expect first RA approval very soon probably in UK.
I have labored on the process of review and analysis by "a panel of independent experts"
If not for the approval purpose, what's the reason for engaging a panel of independent experts" for "preparation and publication of data," it just reminds me of ADCOM. Of course it's not ADCOM which will be publicly announced, but serves a similar purpose.
Or is it required by RAs or purely Linda's idea heeding the recommendation of steering committee or advisory board?
Or is just Linda's way of bulletproofing data announcement?
And they need significant operational funds, and they cannot raise funds via issuing any shares.
The quiet period shall be broke very soon!
Yes I sensed that, delayed with my finger hitting the buy button for a while, and finally could not resist and just bought 30K more shares.
Now well over seven figures of shares waiting for TLD!
I know both primary and key secondary endpoints are significant because standard of care has not been improved for decades and the data of blinded and blended is good enough to assure positive TLD reading.
That's enough for me!
Bought one more additional 9k at 1.56, posts done for today, but buying continues
Bought additional 21K around 1.55 today so far. MMs raised white flag and retreated, remembered in the past, MMs advanced up with no resisting a long the way.
In these artificially retreat and advancement without "any" resistance where have most traded shares go?
Not the vast majority of shares to to retail of course.
As I said I am buying!
Standard of Care has no changes for decades in terms of patient survival.
Primary endpoint and key secondary endpoints are significant
Approval of DCVax-L is not whether but when!
Survey: When do you buy a stock you have done your DD:
1) When everybody is talking about it ?
2) When nobody is talking about it?
3) When the momentum is subsided with boring social media discussion?
4) When the momentum is picking up with increasing social media discussion?
I bought yesterday, and may continue buying today.
When TLD is ready, we will see a crazy market.
On google page: [where the usual place reserved for Flipper's ihub profile is replaced by] "
People also ask
Is Nwbo a good stock to buy?
NWBO POWR Grades
Sentiment is the dimension where NWBO ranks best; there it ranks ahead of 54.28% of US stocks. The strongest trend for NWBO is in Stability, which has been heading up over the past 31 weeks. NWBO's current lowest rank is in the Momentum metric (where it is better than 9.33% of US stocks).
NWBO -- Is Its Stock Price A Worthy Investment? Learn More.
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VERY INTERESTING!
Bought a pity 32000 shares today adding to an already large pool of long holding shares
This Summer will be very exciting for nwbio as TLD when it's ready it will be released regardless of any seasons or raining or snowing or sand storm.
We only know 5 October last year is the day of data lock; NWBio has been in a quiet period ever since data was unblinded shortly after; Covid pandemic disrupts operation, hindering NWBio's gathering of some peripheral DCVax-L trial data, with core data fully unblinded and known; the market has been confident for months about the ultimate success via TLD release, followed by publication, etc.
The market by now should have fully understood the standard of care for GBM has not had any significant improvement for decades, the significantly improvwd blinded, blended data can only contribute to efficacy of DCVax-L. The market has spoke!
Vacation may be ahead. I have to be fully loaded up, mostly adding. At best, a few cents of price swing, or even a few dimes of swing is nothing worse than missing a few dollars of price gaping up.
When it's ready, it's the time!
Extended or not, insiders would not exercise any shares at this price range, unless nwbio is desperately needing operational money and other holders other than insiders also are reluctant to exercise so as to inject funds to the company.
Judged by what has been happening in recent months, the slow and steady warrant exercise should be enough for nwbio to operate as long as it takes to get TLD.
For me, it's not an issue
FORGIVE ME HAVING NOTHING NEW TO SAY SO AT LEAST I CAN WRITE IN CAPS AND BOLD:
ANYBODY IN THIS BOARD KNOWS MY POSITION AND THESIS SUPPORTED BY VARIOUS INFORMATION AND DATA, INCLUDING ADAPTED SAP, ENDPOINTS, BLINDED PUBLICATION AND FOLLOWED-UP UPDATE OF THE DATA, AND MOST IMPORTANTLY THE STAGNATION OF SOC OVER DECADES.
IN ADDITION, THE REASON THE COMPANY HAS KEPT QUIET IN A SELF-IMPOSED QUIET PERIOD IS SIMPLE:
THERE WILL BE NO CLASS ACTION LAWSUITS AS SHARE PRICE IS ARTIFICIALLY KEPT LOW BY KEEPING MOUNT SHUT; BECAUSE ANYONE WHO HAS BOUGHT SHARES EVER SINCE THE COMPANY WAS IN THE CONTACT OF UNBLINDED DATA WOULD BE A HAPPY AND HAPPIER JOE AFTER TLD ANNOUNCEMENT/PUBLICATION.
ON THE OTHER HAND, IF TRIAL HAS NOT HAVE ANY CHANCE OF GETTING APPROVED BY RAS AFTER REVIEWING THE UNBLINDED DATA, CLASS ACTION LAWSUITS ARE DESTINED ON COMPANY FAILING TO APPROPRIATELY AND TIMELY DISCLOSE, SINCE ANYONE WHO HAS BOUGHT SHARES AFTER WOULD BE SAD AND SADDER JOE, SEEING THEIR INVESTMENT THROWN IN THE TOWEL.
FOR THAT ALONE, ANYONE WHO HAS BOUGHT OR IS GOING TO BUY SHARES WILL BE A HAPPY AND HAPPIER JOE. GUARANTEED!
[NOW BEFORE TLD ANNOUNCEMENT IF THE COMPANY HAS BEEN PROMOTING ITSELF AND SEEN ITS SHARE PRICE SKY ROCKETED, THAT WOULD CREATE SOME UNPLEASANT SITUATION: FOR EXAMPLE, IF THE SHARE PRICE TODAY WERE $5, AFTER TLD ANNOUNCEMENT THERE WOULD BE A CHANCE THE SHARE PRICE WOULD NOT REACH MUCH HIGHER, OR EVEN SLIGHT LOWER THAN $5, THEN DEFINITELY THERE WOULD BE SOME UNHAPPY JOES, WHICH WOULD BE A SITUATION WHICH COULD BE EXPLOITED BY SHORTS]
SORRY FOR USING CAPS AND BOLD FONT.
I think it's probably a reason in addition to others [see my post reply to sukus]
GL, I will buy more today.
The issue of concern therewith is Linda cannot partially release information/data regarding DCVax-L 3 trial, particularly ever since the Summer 2015 when the trial was partially halted from screening new patients.
The event was negative despite a few longs suggest otherwise, with the reason probably related to "unexpected" significant pseudo-progression, which in nature was a positive thing to have indicating higher than expected immune-reaction to DCvax vaccine, but it also suggested the flaw of the initial design as Dr. Liau had explained fully shortly afterwards.
Long story short, now the issue of the initial flawed design has been corrected by extending the trial to unprecedented length enabling adapted SAP, endpoint reordering so that the trial outcomes can be appropriately measures.
So the time for a full release of information/data needs to wait until after the now-7-months locked data to be "carefully and thoroughly" analyzed by statisticians, PI, the company, Steering Committee, the Advisory Board, and and a panel of independent experts.
The good thing is for all what we have known, the trial outcomes will be significant, and the vaccine will be approved in all four countries, and beyond, which warrants an "all in" investment as of today.
For God sake, who do you think the relatively high volumes (much more than average) pf trading of the last few days come from?
Most would say, it definitely doesn't come from retails, but a fund or two.
Yes the price could be down some tomorrow, but who are going to sell tomorrow? Retail traders? or Naked short wolfpack? or MMs?
Or maybe not
Men, it's useless to guess these meaningless pitiful trends which seem to be understood by anybody? If so, it would not be called a trend!
The primary and first secondary endpoints will be significant, and nobody knows when TLD will be announced.
LL continually provides / suggests increasingly more detail analyses.
If DCVax-L is worthy of $30 a share, the patents of DCVax-D alone would be worthy at least one billion.