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Maybe it’s ‘AI’ is an acronym for Alcohol Induced?
TY Abeta!! Not they are not already doing this but would be nice for CM to see! Happy New Year & thanks for this analysis, wow!
TY Rocky, great points! HNY!!
And in those few days how much $ are MMs making? Because they are accounted for “only a few days” the ‘buys’ are not displayed which make the margin for shorting greater, right? That’s rhetorical
Grann, I’m sure we all appreciate your effort, I do. Sadly this entity is bought and paid for with zero ability to respond to your inquiries with unbiased, educated and sincere responses.
Why, after all this time of getting paid to create Fear, Uncertainty & Doubt do you “have to laugh” at facts, science, data or truth???? You’re making money to be a lying contrarian, but some things make you laugh… now that’s funny!
fait accompli!!! I see what you did there;)
Funny, but you don’t include denied MTD & Discovery in your SP analysis?
EX, thanks for finally admitting that DCVax-L or ATL-DC are one in the same! TY!
Does the group believe that Nature & NWBO are working together in regard to holding off publishing until an MAA was submitted? I feel if this IS the case it will add so much more impact to the article. Just a thought
RE: MM you state “They are doing their job.”
You need to continue your thought and state “the job they are doing is illegal” right? Why is there a MTD in the courts, filed by MM if they were JUST DOING THEIR JOBS???
Chiugray, thanks for the 60,000 foot view, it’s beautiful!! Also, me thinks yesterday was the day the giant bamboo broke through the soil; and once the sun hits (approval) we go!
You lose!
It’s NOT A DREAM!
Love it!! TY Chiugray
T-cells can’t translocate into a cold tumor… but they can when the tumor is hot! And guess what turns those tumors on/hot? You know LC, say it out loud!!!!
You are a clown and should be banned from this board! Do you have any idea how chemo & radiation POISONS the body? FO
Yes, horrible! You can’t even provide the link to the JAMA article, the “moderators” won’t allow it.
WOW, ic, making up fictitious quotes coming from a nonexistent CRO!!
A truly great example of alternate reality!
With the improved outcomes and little increase in AEs do we honestly believe the FDA will WAIT to approve this combo? If project MOONSHOT is legit they should take one look at the data and say continue trials but available NOW. We need to start helping patients NOW! P2 won’t complete until 2029??? How many melanoma patients will die BEFORE P3 even begins?
From Nature article 12/23: “WE WILL WITNESS THE SUCCESSFUL EMERGENCE OF NUMEROUS THERAPEUTIC CANCER VACCINES”
“Establishing a tumor-specific cytotoxic T cell response remains a pivotal challenge in cancer immunotherapy. The overarching objective of these multifaceted strategies involves selecting a treatment regimen that stimulates effective, durable, and tumor-specific immunity in patients with cancer and prolongs their survival through cancer vaccines. The convergence of innovative approaches, strategic candidate selection, and refined administration protocols hold the potential to revolutionize cancer treatment, paving the way for a new era of therapeutic cancer vaccines. We will witness the successful emergence of numerous therapeutic cancer vaccines with ongoing advancements.”
Sound familiar: “Factors such as TLR agonists, cytokines, or immune stimulatory molecules, can promote DC maturation and activation to further promote DC lymphoid homing.146,147 Immunogenic cell death induces human neutrophil elastase and the TLR3 agonist hiltonol plus breast cancer exosomes to form a DC vaccine that adequately exposed tumor antigens following cDC1 activation in situ and tumor-reactive CD8+ T cell cross-priming.148 Delivering DC vaccines through specific routes that facilitate their migration to lymphoid tissues, such as intradermal or subcutaneous injections, can enhance their lymphoid homing ability compared to intravenous administration.149 DC vaccines can augment the immune response and improve tumor control with the help of ICI or adoptive T cells.150,151”
Sorry… not THE article but a positive section from Nature, published Dec 13, 2023
“The first individual DC cancer vaccine was administrated in 6 patients diagnosed with melanoma. By immunized with a personalized neoantigen pulsed autologous DC vaccine in patients with metastatic lung cancer, peripheral blood mononuclear cells (PBMC) responded strongly to predicted neoantigens, thus expanding the diversity of alternative therapies for lung cancer.136 In a recent phase 3 clinical trial, an autologous tumor lysate-loaded DC vaccine (DCVax-L) was incorporated into the standard treatment regimen for both newly diagnosed glioblastoma (nGBM) and recurrent glioblastoma (rGBM). The results revealed that patients with nGBM who received DCVax-L had a median OS of 19.3 months, significantly longer than the 16.5 months observed in control groups (HR?=?0.80; 98% CI, 0.00–0.94; p?=?0.002), demonstrating the substantial extension in long-term survival of patients with nGBM due to DCVax-L. The study also showed that the median OS for 64 patients with rGBM who received DCVax-L was 13.2 months, compared to 7.8 months for those without DCVax-L treatment. These results from the phase 3 clinical trial offer a newfound sense of hope for the treatment of patients with glioblastoma.”
Let me guess, another conspiracy Vex?
You contradict yourself rather well! In one breath you say the Direct trial was empowered for safety, which it was, but then you say “It (Direct) didn’t do anything.” So I guess those patient survival numbers made up?
Another reminder of WHY we’re here, DCVax-L helping another patient.
“…it is widely known & encouraged by many Canadian investigators & medical team members working with dad…they firmly believe this is the only treatment that could help him…we know of a gentleman, first hand, in Edmonton that is alive 8 years later as a result of DCVax.” $nwbo pic.twitter.com/IWJtvja5K4
— Ida Bogac (@albtur_mnymkrs) December 10, 2023
“Soldiers” fight for a cause, in this case the future of helping cancer patients.
Mercenaries, like yourself, fight for $.
You’ve been gone for some time Grip, and all you got on your return is Enron Linda? Tooooo funny
Buh bye… where’s the link to your “study”?
Yes GC, there were 127 vax trials initiated… of the 127, 27 were successfully able to advance from Phase 1 to regulatory submission and ALL 27 were approved;)
TY Doc! Learning daily from this group, much gratitude!
Incredibly stated… but I don’t think he’ll understand (on purpose)!
Thx for great summary!
True… IC, EX, LC and a few others; skip and save heartbeats
And yet here you are spewing lies! Doesn’t make much sense does it
Dr maybe were being too hard on LC;) I mean he’s only posted more than 12,000 times (as LC that is!1) since signing on in 2012…
TY pgsd! OS was not even mentioned except for # in the graph… cheap
That was awesome Bio!