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Chris,
Is that not for new indication?
He thinks the design of Jelis is not that appropriate
as they used only a low dose of statin.
Thanks for responding and have a great week end. I am leaning
Towards casing out at acquisition as the difference in profits may
be significant.
As always all the best.. and be safe.
http://circoutcomes.ahajournals.org/content/circcvoq/9/2/100.full.pdf
Ok I got your point but I am not convinced. Attached proves that
all cause fatality exist even with triglyceride between 100 to 150 mg/dL
Compared to less than 100 mg/dL. Your thinking is too rigid. Biological systems overlap as
It is not a straight line. As Gabor pointed out to you Marin wanted to capture the entire
Segment from 150 to 499.
Thanks for not quoting verbatim as I requested from you
Earlier.
Last point Jelis proved that pure EPA has pletrotopic effects. It is not only about
Reducing triglyceride level.
All the best
Kiwi:
Would you mind quoting when Dr Budoff
Stated that verbatim?
Thank you
https://www.sciencedirect.com/science/article/pii/S0002914916304842
This is Dr. Budoff’s paper on triglyceride as being in
the causal pathway of disease by integrating epidemiological
Studies and genetic studies.
Does he believe in AA/ EPA approach?
He believes more in remnant cholesterols etc
Enjoy your week end and this should reinforce
Your convictions that ReduceIT will indeed be successful.
Bring the pps at $ 2.50 and I will invest more.
Yes Kiwi go ahead and answer. Please
be honest and do not contradict
all of your previous statements..
All the best
Not a nuclear bomb but rather
A gold mine...
To Gabor:
Will you cash in some upon topline
results and some after buyout
or all at buyout, which may
go well into second quarter
of 2019?
Thanking you in advance,
All the best as always and be safe.
Just because she is a strong believer she has
no credibility. Only topline results from Reduce—IT
can make an objective assessment...Be patient please
.Thank you and all the best.
We are taking about Dr Budoff and you
are no Dr Budoff...
Hi North:
If your baby aspirin dose is 80 mg, would you please
Consult with your attending physician whether
You should continue with it while taking 4000 mg of Vascepa daily?
All the best
No you are not correct. Investors know the history
Of Amarin with FDA. Only the topline results
Of ReduceIT matters. Can you wait for a few weeks?
What is that restlessness all about?...
If your credentials match that of Dr Budoff’ experience
I would have believed you. Until then get loss...
But not clinically significant. Nothing to worry about.
Get ready for paradigm shift...
To Sam81:
Thank you Sir. This fellow was so clear
in his thoughts. Just a few weeks more of waiting
... Have a blessed day for sharing this with us. All
The best
This is what make the Amarin Management great...
Investors, not traders will wait until topline
Results of Reduce-IT clinical trial.
Thanks for trying. All the best
To Anyone:
Would you please a transcript of Dr Budoff’s interview?
Thanking you in advance
Ziploc:
Another reason is to see who benefited when Fda
Messed up Anchor: generic company making Lovaza. They
Wrote the playbook and handed it to fda for execution. What was
Weird it was based on pseudo science....Go ahead and read and you will
be shocked...
So he raised your analysis to 25 % without even
Listening to what he actually stated!!!
AF is always on the winning side... As JL alluded to this
May bode very well for the longs.,.
https://www.ncbi.nlm.nih.gov/m/pubmed/24934470/?i=5&from=/24977981/related
To Akanz:
Conceptually you are missing an important point:
1. Both elevated ldl and remnant cholesterol ( derived from triglyceride lipoproteins)
Cause ischemia but ONLY remnant cholesterol cause inflammation.
2. That is why 4 gram dosage is so effective as it will reduce the inflammation
caused by the remnant cholesterol.
3. That is why after ldl is lowered below 100, there is still residual
Risks of ischemia.
4. The main mode of action of statins is not through reduction of inflammation.
So Kiwi, you are hung up on something that is not correct.
Thank you Tasty for responding.
But did he say 85 percent success to reach rrr between 10 to 15 percent?
The prescribing doctor usually takes care of that if the
patient has an issue with the size of the tablet.
Why would such an md with such an accomplished credential put
his name on the line by guessing about an 85 percent
of success? He must truly believe in the science and
is very confident about himself...
If AF goes low and his fellows bring down the pps further
down hopefully below $2.50! It will be time to load more...
Also Kiwi, alias Akanz:
You do not seem to understand that even when you
Use 80 mg of statins there is still at 65 percent residual
Risks when triglyceride is high ( 150 and above) but not extremely high. When the triglyceride
Is extremely high the risk is only about pancreatitis.
If you read the Anchor trial results it states the higher
The statin dose the more pronounced the Vascepa effects
At 4 grams.
Kiwi. Alias Akanz:
If the separation of events would be an issue based on
Projections and past clinical outcome data, Amarin would
Prolonged study by adding more subjects. Recall that the second
Interim decision was to continue as planned without ANY modification...
For the last time I am telling you this , all from memory:
1. Both ldl and remnant cholesterol cause ischemia but only remnant cholesterol cause low
Grade inflammation. Guess what 4 grams of Vascepa would do with low grade inflammation after
6 years and 6/7 months? You will know very soon..,
Again all the best...
Also Kiwi, alias Akanz:
The pleitropic effects of Vascepa at 4 grams is independent
of ldl level.
Hi Kiwi, alias Akanz:
You do not seem to understand that the pleitropic effects
Of Vascepa at 4 grams is greater with stronger
dose of statins. That is why they went with ldl
Less than 100.
I feel so sorry for you. You are devoid of critical thinking.
Best of luck. All the best as always.
It would be great if your are right.
Yes Jason, way to go...
I am so happy no one wants to spend a second on
you. Calories in and calories out...Right?
Thanks Ziplock and have a wonderful weekend. Are topline results out next week?
Thanks again...
Hello Kiwi, alias Akanz:
You know Amarin completed two phase three
trials. Did you see evidence that it increases
stroke?
Where are all those lies coming from?