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Though you piled on, you were not the first one to question the credibility of the call. That honor falls on the same individual who has never once been right about anything to do with NWBO, and his misplaced skepticism of this call - which started an avalanche - is just another whiff to add to his incredibly long list of swings and misses.
Regarding DI, I'm sure that fewer press releases is just the antidote for an increasingly restless shareholder base. From the tone of this message board, I'm sensing that the dam is beginning to crack.
Yes, it's manipulation. You are being manipulated by the people who run this company. They have been lying to you for at least five years, and it's really remarkable that so many still refuse to see it.
You can pick pretty much any starting point in the last five years, and even skip over that whole confusing stretch in 2014-2015 when everything came to a head with two separate IAs and trial enrollment was halted and then . . . silence. No explanation from the company whatsoever about what had happened, what was going on then, and what the strategy would be moving forward.
Remember when they promised us an article in a top-tier journal that everyone thought would be TLD? Remember how that turned out?
How about when everyone thought we would get TLD at the annual meeting a few years ago, and instead all we got was a vote to expand the potential outstanding shares to 1.2 billion? Not surprisingly, the masochist shareholders voted overwhelmingly to approve that expansion, and now, just a couple of years later the company has blown right past 1.2 billion and is rapidly on its way to 2 billion shares with no additional shareholder approval.
Remember when everyone thought they would announce TLD at ASCO that same year? Yeah, all we got was a dog-and-pony show that concluded with the CEO making a pathetic grovel for money.
Remember when we were told they had submitted an application to NICE? We were told that careful DD had uncovered the actual documentation to prove it. Turned out to be a lie.
Remember in April when the CEO said we would have hard data lock by the end of May? And when that didn't happen, remember how they kept extending hard data lock week after week with at least four printed statements, all of which turned out to be lies?
Remember how everyone got so excited about the plenary session scheduled at SNO. "This is it!" we were told over and over again, and were regaled with exuberant explanations of just how important a plenary session really is. I told everyone at the time that it was just another lie and that they were not going to present at SNO. All you had to do was read the description of the presentation which never even mentioned NWBO or DCVax-L. For providing everyone with that useful analysis, I was thanked with a heaping portion of scorn, ridicule and four-letter words.
Remember when everyone said Linda Liau was our savior? That it didn't matter how awful NWBO was, there would always be credibility as long as someone with the impeccable credentials of LL was involved and out front touting the goodness of DCVax-L? Remember when I told everyone about a year ago that LL had a falling out with the people running NWBO? Yeah, you probably don't remember that because no one wants to pay attention to or remember the things I tell you, but I most certainly did tell you this fact and now you are seeing it play out right in front of you. She has disassociated herself from NWBO completely. Wherever she goes, wherever she speaks, she does not mention NWBO or DCVax-L because she has washed her hands of this epic and disastrous failure of a trial. She has her own vaccine now and is running her own trial at UCLA. She doesn't need NWBO, the company that botched the evaluation of her very promising vaccine, and she doesn't want anything to do with the lying lawyers running the company.
Remember how the CEO, who was a former Enron executive, cut an incredibly shady insider deal to sell Cognate, her own company, to herself? Remember how she "loaned" the company $4.5 million and paid herself back the same year with 18 percent interest? Remember how the wife of one the NWBO executives is being paid $150,000 per year for running the company's laughable compassionate care program? Remember how they continue to pay themselves half a million dollar salaries and reward themselves with bonuses every year for meeting fictional performance targets? Remember how in just the past year they pulled off two or three pump and dump schemes where they raised money by handing out cheap warrants, and then made false pronouncements (like hard data lock by the end of May) to temporarily jack the share price so their buddies could cash out and make a quick buck? Remember how none of the executives of NWBO, save one board member, have ever bought any shares on the open market? Remember how they lost their OTC status and got dumped to the Pink sheets because somebody got the flu and forgot to mail in the registration? Remember how they hired an "executive" from Merck that everyone thought was part of some elaborate buyout scheme, but instead after seven months he took a look around and said, "Yikes, I'm outta here." Remember how they hired a CFO to appease the regulators, and then the new CFO refused to sign off on the long-delayed 10Q so they demoted her? Remember how the Securities and Exchange Commission has been tailing this company for years because they know something's not right?
The list above is just a few of the fond memories we've all come to treasure over the years, but there are so many more. The people who post here day after day will tell you these appearances are all superficial and mean nothing. Those of us who live in the real world will tell you that companies with successful products do not behave in this manner. So, yes, you are being manipulated alright. What is sad and embarrassing is that you allow it to happen considering the overwhelming preponderance of evidence, but there you go.
Yeah, you keep going with that top-tier journal theory. That's a great one. Ranks up there with flipper44's ESMO theory. We'll see how that works out for you.
Everything I have been telling you for the past two and a half years is turning out to be true, and the thing is, you know it. Everything this company does is a disappointment, and there's a reason. The reason is that they have nothing. Only a company that has dragged out a trial 13 years and still has nothing would behave the way this company does. A company that had successful trial results would not behave this way, and you know it. Everyone knows it, despite their allegiance to the narrative. All this company knows how to do is play games, and they do it with impunity and with no regard for common shareholders because they know they have an army of sycophant apologists like yourself who make excuses for everything they do.
They know the results of this trial and they have known those results for five years. They've been lying to common shareholders ever since, while at the same time they have bee enriching themselves and privileged shareholders. You know this is true. Every action the company takes further confirms the charade. No scam can continue forever, and neither will this one. I still think they can squeeze another year out of this without releasing the data, but we'll see. They definitely have an escape plan by now. At least they think they do . . .
How'd you hit 'em today?
There won't be any data in the abstract. Nor will there be any clue about TLD.
Look, people on this message board have been telling us for weeks that TLD would be presented at SNO. How can people listen to those who have never once been right about anything to do with NWBO - not once - those who told us all about how the SNO presentation would go and the importance of the plenary position and blah, blah, blah, and are now telling us that the new target conference for TLD release is ESMO in December. It's beyond comical. The ESMO projection comes on top of the dozens and dozens of other projections that have been made in the past that never, ever turn out to be right - and yet, the projections just keep on coming (more than 22,000 posts in one case!). Some folks should have a better sense of self-awareness, in my opinion.
I told everyone that the SNO presentation would not happen, but no one wanted to listen. That's fine. I get it. People with dollar signs in their eyes don't want to hear things that don't fit their get-rich narrative. But I've been saying for two and half years that this company has known their trial is a bust since at least 2015, and no one wants to hear that either. For the last five years they have been living a lie, and the reason they are so reticent to communicate is that they know they are living a lie. Maybe they really believed they could change the trial endpoints after the fact and everything would just sail through like it was no big deal, I don't know. Maybe they really thought it would all work out, and they could get away with all this nonsense without sharing any of the strategy with shareholders.
Do shareholders even understand that the company has never once outlined it's strategy for the DCVax-L trial? They never once have told us that a) the IA in 2015 was bad news, and b) that the new strategy would be to wait five years and then change the trial endpoints. I mean, at some point it became obvious what they were doing and occasionally the CEO would mention home runs and such, but they've never once shared that information - the actual strategy - with the common shareholders, you know, the owners of the company.
It's a real shame that they botched this trial so badly, because DCVax-L was a really promising product. Here's another nugget for you that no one wants to believe: the creator of DCVax-L, Dr. LL, no longer wants to have any association with NWBO. It's pretty obvious. I was surprised to see her name on the SNO presentation, but not at all surprised to see the presentation subsequently canceled. If anyone has an opportunity to hear her speak today, pay attention to how often she mentions NWBO. She won't mention them at all. And now she's running her own trial for the vaccine with no mention of NWBO or even the name DXVax-L. She has become disillusioned with the people running this company because they are an embarrassment, and she regrets ever associating with them in the first place.
The way this whole trial has been run is an embarrassment, but it has become especially egregious in the last six months, starting with the promise at the ASM that data would be hard locked by the end of May. Since that statement, literally nothing they have told us has turned out to be true. Everything about these lying lawyers is a shameful embarrassment, and the thought that these people could ever get a product approved by the FDA is a ridiculous notion that flew out the window a long, long time ago.
The schadenfreude is pretty heavy right now as I watch this disaster begin to unfold. No one wanted to listen. I just get a kick out of the extraordinary lengths some go to to defend and make excuses for the incompetent people in charge of this company. Now there is an actual excuse being floated that because the company signed up for a conference, which is a pledge and commitment to present at that conference on the date scheduled, that when the company did not honor that pledge and never told anyone or gave anyone a reason why, it is actually the conference's fault that the conference still shows them as scheduled to present. OMG, some people are so detached from reality, the reality that is actually happening around them while they just choose to ignore it. Some of them even strive to ban the thoughts of those with whom they disagree, as I have found out. It's kind of scary because everything I've told these people has turned out to be true, and everything they have told us has turned out to be a lie. Imagine that.
I will tell all of you one more thing - be careful today and keep your eyes open after market close. I'm not a sage, but I am pretty sure that whenever we do eventually get news about DCVax-L, it's going to be delivered on a Friday afternoon.
Wow, I wrote the post below without even realizing they had bailed out on SNO. OMG! One of these days you people are going to wake up and start listening to me. This whole trial is an epic disaster and the people in charge do not know what they are doing. They are not going to present TLD at the pretty poster contest, either. What a joke! Everything I have been telling you people for the last three years is true. They have been sitting on a failed trial for more than five years and they don't know what to do. Wake up!
Yes, it's really amazing, isn't it? You would think they would learn, but instead they just keep doing this over and over and over again, year after year. You would think the one who created that list several years ago, the one who has never once been right about anything to do with NWBO (literally not even once), would be a less-than-ideal model to emulate. But no, they're going to keep throwing out these upcoming events with breathless expectation, and then, when these events turn out to be epic disappointments like they always do, they'll just move on to the next supremely important future event.
I have a hard time understanding the mindset. I guess it's a combination of them thinking they will be heroes combined with the fact that there are no consequences here for wrongheaded analysis. Their unbroken streak of wrongness certainly doesn't seem to have hurt their credibility. When the SNO conference comes and goes with no TLD, they'll just move on to the next date on the calendar - probably the yet-to-be-scheduled ASM. Their analysis is based on what they want to happen, but fails to consider the single best indicator of future behavior, and that is past behavior. To know what is going to happen at a future NWBO event, all you have to do is look at what has happened at every single NWBO up to now. That's really all you have to do.
Of course it was warrants. What else could it be? Amazing that some people would go to extreme lengths to deny that, but why? Because it makes company management look bad? Oh, boy, well their denials are going to sound especially meek on Monday, which is going to be a bloodbath as 150 million shares flood the market. People are also saying that these warrant holders would never sell - they are too principled and too patient to be so impulsive. LMFAO! Good luck with that theory! Those folks are going to be in for quite a surprise when they discover the true nature of humans.
And lastly, there are several on here - and one in particular who has never once been right about anything to do with NWBO - saying with absolute certainty that TLD will be shared and discussed at the SNO meeting in late November. There is no reason to think that will be the case. None. The description of the event doesn't say one word about TLD, DCVax-L, or NWBO. The company has said nothing about when TLD will be released. And there's another little secret that no one on this board wants to discuss, and that is that Linda Liau is not on friendly terms with the people running NWBO. She does not like them, not one bit, and who can blame her after the disastrous way they have managed this trial to test her vaccine? She's running her own trial now and isn't associating it with NWBO in any way - even to the extent that the vaccine she is testing, interestingly, is not called DCVax-L even though it is effectively the exact same thing.
In April the NWBO CEO told us data would be hard locked by the end of May. Shockingly, it wasn't. She just flat-out lied to shareholders again. Then they lied over and over again as they extended the hard lock week after week all the way until October! What a joke. To assume that TLD will be discussed at SNO is preposterous. It won't be, except for the usual "Stay tuned." Anyone who thinks that just doesn't understand how this company works and hasn't been paying attention. After 13 years, do people really think these lying lawyers are finally going to release the data from this failed trial? The same trial that they are now changing the endpoints on in a desperate attempt to make the data look good? Sorry, but you can't just change the endpoints on a trial after the fact despite some of the misinformation you see on here. It doesn't work that way. It just doesn't, and some people need to stop kidding themselves. I don't think NWBO is going to release anything. I think the whole thing is a scam, and the past couple of weeks have been a huge pump and dump that is making the lying lawyers rich. Next week they will flood the market with 150 million shares, the sale of which will make them even richer, and us a lot poorer unless you were smart enough to sell at $2.48. That's all they care about right now - how rich they can make themselves before the scam implodes. That's why they froze the warrants until the pump and dump was well under way. They don't care about you, the common shareholder. I can promise you that.
I'm not sure that all of those here offering you advice fully understand your situation. I believe that you have stated more than once that your entire retirement nest egg is invested in NWBO. Is that not correct?
If that's accurate, you make out-of-control Vegas gambling addicts look mild. If you do, in fact, have everything tied up in NWBO, someone gave you some very bad investment advice to begin with. And for you to now even consider not taking some profit is beyond foolish. If you think the risk of this stock is behind you, you are kidding yourself (and misleading your wife). I know I'm one of only a few doubters here, but I can pretty much assure you this is far from settled. The odds of the RAs accepting an SAP that was crafted to match the data after the fact are not with NWBO; they are against NWBO. That's a fact.
You certainly don't have to take my advice. Consult a professional - like, tomorrow. They will tell you what you are doing is way beyond any definition of sanity. But if you are willing to risk your entire future, and, perhaps, your marriage, too, on a binary event that requires you to trust established liars and incompetents, then you've got balls, I'll say that. At this time it might do you well to re-watch one of those Big Biz episodes and ask yourself if you are really willing to trust your entire future to that.
I don't think $1.00 is much of a floor or a ceiling. It hit $1.16 and was rising fast before they announced they sold warrants at $.81. Frankly, after that deal I'm surprised it's still hanging on over the $1.00 mark. I expect it will rise a good bit as speculation about TLD gets more intense. That's when I plan to sell off the majority of my modest holdings. I'll hang on to some just in case it turns out I've been wrong all this time, but don't think I will be.
Why? The binary announcement is whether any regulatory agency is going to allow them to change the endpoint after the fact. It's either a yes or a no, and precedent says the answer will almost certainly be no.
A lot of folks here are getting awfully giddy about a situation that hasn't changed fundamentally in the least. What is happening right now is exactly what I have anticipated would happen, and exactly what I have told everyone here would happen over and over again. I have told everyone here numerous times that they would try to change the endpoints of the trial. If you recall, the overwhelming consensus was that I was nuts. "Change the endpoints? Are you crazy? They would never do that, and they don't need to do that because PFS is stat sig, blah, blah, blah . . ."
Well, now that it's clear they are trying to change the endpoints everyone here is acting like that's a good thing. The mentality here is just amazing. Let me be as clear as I possibly can be: CHANGING THE ENDPOINTS OF A 13-YEAR-OLD TRIAL AFTER THE FACT IS NOT A GOOD THING.
In fact, it's a total concession that the 13-year-old trial is a failure, which is why they didn't PR it. They just raised another $12 million to plan their island getaway. Everything is proceeding exactly as I have told you it would. Nothing has changed. It's the next part that no one is going to like very much. But, don't say you weren't warned.
F----d around and got a triple double.
The failure of the trial's primary endpoint is now good news?
Because PFS is, or was, the primary indicator on this trial. What you are reporting from the EU is that PFS failed, which is exactly what I've been telling everyone on this board for two and a half years. The primary endpoint failed and they've known it for five years. Now it looks like they are trying to change the primary endpoint after the fact, which it appears they've done on the EU site.
Great, bully for them, but I don't think this means what everyone here seems to think it means. You people see so narrowly - straight ahead through your rose-colored glasses - that you don't see the freight train coming from the side that is about run you over and destroy you. That train has been coming at you for a long time, and it's a great metaphor because it's almost here now and that freight train has been blowing its horn like crazy trying to warn you, but you just can't seem to hear it.
So funny. You guys can rip on where this guy Tweets from and that he's a kitchen installer, but you have nothing to say about the actual arguments he makes. You're going to be quite shocked to find out almost everything he's written is true.
As I've been telling you for a long time, this is a failed trial, and thanks to the unreported IA they did in 2015 the company has known that the primary indicator failed for at least five years yet neglected to share that information with common stockholders and neglected to mention anything about the primary indicator in their supposedly world-changing interim data report that they paid to have published in a third-rate medical journal.
Now, they remain blinded but have been playing games with the OS data trying to get a positive result and are not having any success. We all know they locked this data a long time ago. That's why she told us end of May, and that's how they got on the SNO agenda. They haven't seen the data but they've told the analysts to keep manipulating and parsing the data to compensate for that little crossover problem until they get a positive result. So far the analysts have not given them a thumbs up, which is why they didn't announce the data lock in May, or June, or July, or August, or September. Hmm, looks like that data's turning out to be quite a problem, just as I have told everyone here for years now. It's a mess. That's why we've had all the delays and missed timelines, which I know you don't care about but in the actual business world where people do actual business and are knowledgeable about business and how business is done, delays and missed deadlines are a very very big deal. But we understand why you wouldn't think so.
So, I see we are already putting together the list of Really Tough Questions for the next ASM. This board is like Groundhog Day, an inescapable never-ending cycle of insanity.
At the last ASM, the CEO said we would have hard data lock by the end of May. Then they revised that timeline three different times, even after telling us in writing that they had all the data in hand. That's what they said - they had all the data and weren't waiting on anything else. And yet they still never locked the data, even after the ASM statement and three additional statements in writing.
Then they said that something would happen by the end of September. There's some dispute over what exactly that would be - data lock or TLD - but the one thing we all agreed on was that something was going to happen by the end of September. But nothing did, and the company has chosen to not explain what is going on.
Now we have insufferable speculation about buyouts, partnerships and waiting for the government, whatever that means. It's all a waste of time, people. That's because it's all a lie. If you don't want to believe me, that's your prerogative, but you simply can't go on pretending that there's not something seriously, seriously wrong.
Your response to this Twitter thread is typical, full of ad hominem emotion and no facts. This Twitter thread summarizes, more clearly and more specifically than I have been able, what I have been telling everyone for two and half years, but no one wants to listen because these obvious facts run counter to their emotional investment. It can all be boiled down to one simple point: No one has an answer why, if the data from this P3 trial had been successful, we didn't hear about it a long time ago. But we didn't. The company has known for five years that this is a failed trial. Five years! The settled lawsuit has nothing to do with the IA that was conducted in 2015, and the ones who keep harping on that lawsuit as if it resolved the issue know they are being disingenuous. This company has been playing games for five years, enriching themselves and treating common shareholders with absolute disdain through their inadequate, infrequent, insufficient and misleading communication, and pumping the share price with false PRs so that their buddies could cash out. Those of you who sold at $.90 were smart.
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1/) $NWBO Spoiler alert: it seems many (all?) longs don’t realize that the PFS primary endpoint already failed years ago, and in fact (and like with $CVM) the DMC noted an excess of recurrent disease events. Let’s talk about what happened already and what will happen soon.
2/) In 2015, the CRO conducting the DCVax-L phase 3 trial ran the second of two planned efficacy analyses, and noted an excess of PFS events in the treatment arm; i.e., there was no way the study would succeed in meeting its primary endpoint. This info was relayed to the DMC.
3/) The DMC advised the sponsor $NWBO) to halt enrollment in the trial because there was no longer any possibility of success. It’s likely that they also noted futility in OS as well.
NWBO refused the advice, and continued enrolling ndGBM patients.
(4/) This created an ethical (equipoise) issue as all subjects underwent a highly invasive leukapheresis procedure. The FDA stepped in and placed a clinical hold on the trial with ~331/348 enrolled. They refused to lift the hold until NWBO closed the trial to enrollment for good.
5/) This should all sound too familiar to $CVM bulls, as the same happened to the IT-MATTERS trial, only in that case the FDA almost certainly saw exacerbation of PD/death in MK arm, as IL-8/IL-6, which is what over 80% of MK is, is essentially MiracleGro for tumors.
6/) In $CVM ‘s case the DMC even remarked they were “deeply concerned about patient safety” should Cel-Sci go through with its plan to upsize the trial from 880 to over 1,270, and total deaths to end the trial from 298 to 394. FDA justly stepped in and put a stop to it all.
7/) $CVM was forced to close accrual forever at the point of the clinical hold, just as happened with $NWBO.
Why would FDA not allow CVM or NWBO to enroll any further subjects? Because the treatments are absolutely ineffective and/or even deleterious to patients.
(8/) In $NWBO ‘s case there was the added issue of leukapheresis. FDA cannot know that a treatment is ineffective and allow subjects to be enrolled in a trial where they must undergo a life threatening procedure to get it.
9/) So what did $NWBO do? The only thing they (and incidentally $CVM) could do to avoid having their trial forcefully terminated by the FDA—close it forever to further accrual, removing at once any legal basis for termination or even a clinical hold.
(10/) NWBO in effect maintained the blind, as they did not receive the data from the CRO (and it was a soft lock, or “snapshot” analysis anyway, being interim only) and of course the OS endpoint was still immature. So they did what Vical $VICL now $BBI) did—buried the primary,
11/) and refocused all attention to the secondary OS endpoint. In Vical’s case, they too became aware that the primary ORR endpoint in their Allovectin-7 trial was a bust, but that there was still hope the secondary OS ep would succeed.
(12/) This created the ultimate carrot-dangling scenario as they had recruited exceptional prognosis patients into their study. Years went by and no conclusion. They pumped this as “well, everyone is living longer so it must mean AL-7 is working!”
13/) And it is true that the blended survival was extreme compared with historical samples. Control group assumptions were ~7-9 months mOS. Call it 12-14 in an absolute top scenario. However, the blended survival for the trial was over *20 months*. It must be working, right?!
(14/) Wrong. When data were finally unblinded, everyone was stunned to learn that the control group had performed an astounding 24.1 months (below). Not only this, but AL-7 group performed significantly worse at 18.6 months:
15/) This is simply a tried and true stock pump methodology. And as long as investors continue to allow this terrible theology to promulgate (“but the blended survival is so high! It must be working!”), it will continue to destroy wealth.
So what will become of $NWBO?
16/) Here is what has and will happen:
(1) PFS failed years ago. They will blame it on pseudoprogression. This is a farce as nearly all subjects had 100% resection (and the main reason why blended survival is crazy high);
(2) OS will report as a failure, but...
17/) ...they will explain this away as due to crossover, whereby 90% of all subjects received DCVax, either initially or post resection. They will pin the lack of separation between groups as due to placebo group being allowed to receive DCVax after PD, making them live longer.
(18/) They might even compare it with Avastin in this regard, where it was hypothesized that crossover caused the AVAGlio studies to fail.
(3) Some subgroup will probably show an efficacy signal for DCVax-L group. But it’s unlikely to be statistically significant.
(19/) And being post-hoc, won’t mean anything to regulators. But they will pump this as a promising group to explore the efficacy of DCVax in future studies, and may even state they will seek the advice of FDA as to whether or not they can get approval for this subgroup now.
20/) The SNO late breaker had to be submitted by Sept 1. Key insiders absolutely knew of PFS/OS by that time, and that it failed both endpoints (otherwise they would have unblinded other insiders to the success, and we would have been treated to a press release stating as much).
(21/) Since then the sundry subgroups are being dredged for any positive signal. We should get a press release soon citing the fail in PFS/OS but some positive signal or other, and the stock will fall < $0.10.
The only other path is they go dark until SNO in Nov.
22/) But if they do that everyone will know it failed and the stock will bleed back down before ultimately going < $0.10 anyway. This would certainly be more $NWBO ‘s style, who has been incredibly cruel to shareholders over the years. $CVM has at least been much more open.
23/) Let’s sum it up:
-PFS already failed years ago; given this is the primary endpoint, the study itself failed years ago
-OS will be shown to have failed also; NWBO will make up the excuse that crossover is the cause, but a fail is still a fail
24/)
-Some subgroup will be highlighted showing “efficacy,” but probably won’t be statistically significant.
-Nothing in the data will be useable for BLA filing purposes, but NWBO will try to keep the dream alive and make some remark that creates false hope it’s possible.
25/) A vaccine containing live cells that is supposed to migrate to lymphs to work but never migrates, *can’t work*. An identical vaccine injected right into the lymphs still failed (PFS and OS). This couldn’t be any more doomed if it tried.
[From a long twitter post by Medical Reaearch Collaborative]
This makes no sense. If they were getting bombarded with emails, removing the description would surely result in twice as many emails, as evidenced by your group's inquiry. There has to be another reason, and I can't think of a good one.
The can kick is coming. Better have your stops in place.
Here's what is coming:
Start with what we know:
- PFS failed (95 percent certainty. The company hid PFS from the 2018 interim data, and everybody knows if PFS had been successful they would have told us five years ago.)
- The trial is a mess. There are major validity issues with the data due to the way the trial was run.
- The survival effect of DCVax-L may not be provable.
I believe the company has known this reality for five years and has withheld this information from shareholders. I also believe they are now planning to present the data in the oversimplified form of, "While the data does not confirm efficacy, here is why DCVax-L should nevertheless be approved . . ."
I am eager to see what that argument will be. Perhaps it will even be persuasive and successful. That would be nice, but I'm not counting on it. I think most of us know this scenario is most likely. The stock is going to tank when they present this news. Better have your trigger fingers ready.
So you are expecting bad news? Because that's all you are going to get on a Friday.
Do you people know anything?
InsiderFinancial appears to be a simple pumper operation. Companies pay them to write articles like this one and disseminate them widely. There is a disclaimer at the bottom that states they do not own any position in the stocks they are paid to pump. Wouldn't surprise me if DI provided the content for the article, but I doubt very much that he actually is InsiderFinancial. The posting history shows they pump a wide range of companies, mostly biotech but not all.
In all my years of posting here, you are the first one who kinda sorta gets it.
The odds of data being positive are extremely slim. If the data were positive we would have heard about it a long, long time ago. There's no getting around that simple fact.
Why are they releasing the data now? Have any of you stopped counting your new yachts and beach houses long enough to ask yourselves that question? Because it's a really good question. After 13 years, why now? Is it that we are now five years past enrollment? Personally I don't think that has anything to do with it. Here's the real reason:
They are out of money.
They have no more shares to give away at $.14 without coming back to shareholders to ask them to approve more, and we all know that's not going to happen. They've played this out as long as they could, but now they are out of options for raising any significant new funds. They can't pay themselves anymore. So that is why they have finally thrown in the towel and decided to release the failed results. Think about it.
By saying, "we think this study is going to be a major contribution to the field in terms of data," the CEO wasn't exactly brimming with confidence about the product that data is attached to. Yes, she followed that with a tepid statement saying she "hopes" they get approval, but she's been saying that for 13 years. They know what's coming, and they've known it for the last five years.
On another note, has anyone here investigated whether there is any kind of personal relationship between anyone at NWBO and the two principals at Flaskworks? I'd be interested to know whether this was actually a research-based acquisition, or if it was just another in their long list of buddy-buddy shenanigans. We know how they love to make their buddies rich whenever possible. Wouldn't surprise me if there is more to the Flaskworks story than we know.
This quote doesn't give any indication of positive data. In fact, the words she used - which clearly were very specifically chosen - and her unenthusiastic tone of voice as she said them, suggest a lack of confidence in positive data. The fact that she chose to say "we think this study is going to be a major contribution to the field in terms of data," is her way of saying she knows this is a failed trial, and has known it for five years. It's her way of saying the trial may have failed, but it's still going to be helpful research that others will be able to use as an example of how not to conduct a trial. It's sad, and in many ways unconscionable, that they allowed this travesty to drag on for 13 years.
Or, and this is the far, far, far more likely scenario based on past experience, they are not presenting TLD at SNO as everyone here seems to think. As is so typical with this message board, people read an announcement and immediately jump to the false conclusion that TLD is definitely on the agenda. Bullshit. The conference announcement says nothing about TLD. NWBO hasn't even locked the data, dude. Why do you people play this game every single time? Why do you continue to get played by these people every single time? Do you never learn?
Apparently not. We've done this same routine a hundred times in the past and it never, ever amounts to anything. You know that. So why are you once again hyping and pumping something that in all likelihood is not going to happen? Why? Do you savor disappointment that much? Are you a sadist? I mean, WTF? Give it a rest for god's sake. These lying lawyers have never produced anything, and the person you are responding to has predicted this, that, and everything in between dozens of times over and over again and has never once been right about anything to do with NWBO! Not once! Jeez, the only explanations are paid pumping or certified insanity.
I don't see any mention of the data analysis that you misleadingly put in caps as if that's the official stated purpose. Where does it say that?
They haven't locked the data yet. Why not?
I'm happy for everyone here, including myself, that we are seeing a little bump on the news of the Flaskworks purchase. I hope it continues and I hope it portends good news on the Phase 3 trial. You all know where I think this is headed, and I don't think a $4.33 million purchase necessarily changes anything (although I will admit it was an unexpectedly bullish move). I think we all know the hard part is yet to come and there's still no sign of it, but, for now, I think we all can enjoy a little run. Have fun, but be careful . . .
$4.3 million? Man, that must be some revolutionary technology.
A while ago I posited that eventually this message board would whittle down to just a few of the clinically insane, those left mentally warped and delirious by five, ten or 15 years of waiting for nothing to happen, repeatedly typing "Great post!" among themselves. Well, it sure looks like we are gradually, ever so gradually, getting to that point. There hasn't been anything of value posted on this site in quite a while as nothing, and more nothing, and then nothing, and once again nothing, continues to happen at an astonishing rate.
It's pretty clear this company is not going to tell you what you want to hear. When are you going to figure that out? You've been predicting data lock and TLD is coming any day literally for years now, and in the meantime you've been parsing this number and that number and trying to predict how many survivors there are when it's all just meaningless blather. The people in charge of this company are playing a game that has you all waiting like abandoned puppies left by the side of road. You all know that at this point the odds of success are next to zero. It's sad to watch, but still you persist. I feel for you, I really do, but I can't help but think you would be better served re-evaulating your view of what is actually happening here.
There's a simple answer - an obvious answer, but it's one so many of you refuse to see. What will it take before you finally get it? It's going to be fascinating to watch as the sudden realization of, "Oh, crap, JRIII was right about everything all along," creeps across what remains of your brain cells. I won't rub it in, I promise! Meanwhile, great posts everyone!
$1? Wow, you sure have tempered your expectations. Hell, even I would agree it'll hit $1 if TLD is positive. But we all know that's not going to happen because if TLD was positive we would have heard about it a long time ago, and they wouldn't be putzing around playing games and refusing to even lock the data like they are right now. We all know that, even you, although you are loathe to admit it. You know that what is happening (or, rather, not happening) isn't right. You know that something is very, very wrong with this trial and with this company. Despite the optimistic face you've been wearing for years, you can feel failure in your bones.
It should be great news, but it's not. People here ought to think a little more carefully about what they read. I work in the communications field and I know a distraction press release when I see one. That's all this press release is - a distraction. It doesn't really tell us anything. The only news it relates is "double shifts" which is something they just made up to make it sound newsworthy because it's impossible for any of us to verify.
This press release is intended to distract your attention away from the bullseye - the reality. The reality is that despite numerous promises they still haven't locked the data and they still are no closer to TLD because there are major problems with the data and with the trial overall. It's just another public statement that whether it's construction at Sawston, locking data, or releasing TLD, they still haven't actually completed anything.
They know that almost everyone on this message board will inhale these dog-treat PRs like good little lap dogs, even when the "news" doesn't actually advance the process one bit. Anyone who thinks this press release actually conveys anything of significance is a fool.
The second reason they put out these distraction press releases is to spur a quick bump in the share price so their buddies can cash out from the financing. They have done this more than once, so keep your eye on the trading action.
NWBO is nothing but a scam.