Lincoln Park Capital Fund's past performance in the majority of companies that use this vulture fund show a sp decline of 38%. There are two ways to view this, though, as good or bad. Personally, I see this as an upcoming buying opportunity. Our ceo, Drysdale, seems a cut above the rest, IMO.

All of that sounds great. Still have my fingers and toes crossed. Is there a doctor in the house?

Maybe you are right. But I have been here 8 years so patience is not the issue. Could be, as you say, it takes a long time. Or it could be you getting caught up in the insanity yourself. Happy investing. Or maybe happy, happy investing is more appropriate. There is a place for happy, happy people. Maybe this is it,

Insane? The definition of the insanity of continuing with my investment here is me believing we are about to take off when each of our trials produce great results and nothing happens. Then believing Missling wants to get things just right. Thinking this time after time and expecting a different result sounds like insanity to me. I am at some stage of becoming a non-believer. WTF

What is beyond weird is biogen's past halting of aducanomab's (sp?) trial, then changing endpoints to reducing amyloid plaque and the FDA approval being based on that alone without consideration of the drug's efficacy.

Is this all a numbers game, calculating how much it costs the govt per year per persons over age 65 to survive vs allowing folks with AD to die by approving drugs that either don’t work or hasten death. I’m pretty sure AD will be on the list for euthanasia when that comes fully online. Add to that, the number of CNS diseases with no real cures on the market. What is the math that says a treatment that works to prolong the lives of populations no longer able to contribute financially to society is more cost effective than allowing people to die. Just trying to figure out why 1 + 1 doesn’t seem to equal 2 here. Why are biogen’s drugs being approved in lock step fashion. Maybe I think too much.

We can change the delivery method and receive a new patent.

Will this give our share price a boost?

https://finance.yahoo.com/news/virginia-community-health-centers-aetna-140000796.html

Cipcipcipcipcip

Which way are we going?

Don’t Think. You most certainly are setting yourself up for disappointment, in my opinion.

We have a very impressive CEO:

https://milkeninstitute.org/events/a0c1u00000cf19buar/speakers/doug-drysdale

Yesterday’s Panel discussion at Milken showed how far ahead we are in the quest to revolutionize the mental health care system.

Or if there were a drug that restored homeostasis....oh....I think we were told that our drug does that. Hate to say it but it’s begining to seem Missling is indeed selling snake oil to us investors. Sorry.

Too bad we couldn’t help this guy with Parkinson’s Disease or the folks with Alzheimer’s Disease or the girls with Rett Syndrome or the kids with Autism Spectrum Disorder. We don’t have time for that stuff...too busy doing never-ending clinical trials with no results:

https://www.msn.com/en-us/entertainment/news/michael-j-fox-reveals-heartbreaking-end-of-life/ar-AA1aExCe?li=BBnbfcL

It's called setting up for a takeover IMO.

Sad. Thank you for posting. Let's hope we can help settle the score for the kids and their families suffering from this horrible disease.

Patience is a Virtue, a very rewarding virtue for CYBN Longs, IMO.

Looks like a Hail Mary Pass to me.

Seems to me, A2-73 is being used as a substrate to identify the percent of binding to sigma 1 receptors or to quantify sigma 1 receptors.

Maybe he is getting tired of all of the smoke and mirrors too; new former FDA hires, new patents, data coming, etc. Anything shy of data is just that, smoke and mirrors, IMO.

It seems to me Dr Missling is lining all his trial data ducks up for a takeover. That’s what small bios do. Anyone looking for an accelerated approval for any of our indications will continue to be sadly disappointed, IMO. Sitting on the edge of my seat expecting takeoff, defies logic for me now. Missling doesn’t act like someone gearing up for commercialization. He will do very well with a takeover. I hope shareholders do as well.

How do we get approval if we don't bring our results to the FDA? We are not a one trick pony company. All of our trials had positive results. Why don't we make our case before the FDA for anything? That would open up the off label market. Something aien't right here.

Dr Missling did tell us many years ago that patients may need to be taking A2-73 for an extended period of time to receive maximum benefit, so this result may be proving him right. I wouldn’t want to be in a Fox hole with DM though, my weapon works, very efficacious, saves a lot of lives. Arrrhhh, how Do you pull the trigger?

As a shareholder, you have no right, absolutely no right, to any information on anything the company is doing or not doing. Dr Missling is the Leader. He is the ceo. Even if he is a fork up, he is still king of the mountain. I learned what my rights as a shareholder are, on this mb. Just thought I would share this wisdom.

I thought shareholders were part owners of the company. Why does begging for crumbs of information occupy so much space here? Missling seems to rule like a dictator. I’m usually not radical in my thinking but a shareholder uprising would suit me fine.

Great questions. I have been here from the beginning. Our lack of seeking approval for Alz, Rett, PD, Sleep…Something, is mind boggling on some days. Other days are more hopeful. With all of our successful trials, seeking approval for any neurological disease seems remotely possible. That’s when I’m believing Dr Missling knows what he is doing. Other days, forget about it.

Curious to know what it will take for Missling to “Come out swinging.” Phase III trial for Adult Rett Syndrome met Primary and Secondary endpoints over a year ago. What will it take to get the adrenaline pumping in this guy?

https://www.anavex.com/post/anavex-2-73-blarcamesine-avatar-phase-3-trial-met-primary-and-secondary-efficacy-endpoints?fbclid=IwAR1dEv4FH5FRCcM-iaSwPYCiFi5T2vCd1VgOGNkJ674IEOh1RrUBOZz0aGg

It is my belief in the Science that keeps my shares under lock and key. The cabal may try to generate fear.

Warren Buffett once said that it is wise for investors to be “fearful when others are greedy, and greedy when others are fearful.”

If my expendable finances allow and the cabal continues to succeed in bringing our share price down, I will be reloading.

There is a difference, a big difference between a clinical trial and Right To Try.

https://www.fda.gov/patients/learn-about-expanded-access-and-other-treatment-options/right-try

Bruce Willis’ family reveals he has Frontal Temporal Lobe Demetia. Seems a good time for 2-73 ‘Right To Try’ as there is no available treatment.

This isn’t your parents FDA. We are transitioning to a vaccine oriented medical system, IMO. It has only been a few short years that medicine ads now include potential side effects. Many of them seem horrendous, including death. What is that about? For me, after listening to side effects of some advertised drugs causes me to think, I wouldn’t take that. Maybe that’s the response that we are being conditioned to, so a vaccine would seem more preferable. Haven’t heard any vax side effects during ads. During Covid, you couldn’t board an airline if you were unvaxed. Canada gave a glimpse of other consequences. I am not anti-vax for those that want it. I prefer a pill. Will FDA approve 2-73 near-term? Hope so.

If “Cancer Drug” Keytruda can be approved by the FDA for numerous types of cancer, not withstanding a plethora of side effects, when will they approve a “CNS Drug” that succeeded in every Clinical Trial with minimal side effects. Presenting our case for 2-73, to the FDA might be a good start. At this stage of our development, I can’t see us seeking approval for Rett, then for Parkinson’s, then for Alzheimer’s Disease, then for Autism, then for MS, then for….ad infinitum. Come on Dr Missling, millions of your fellow men, women and children are waiting for you to step up. The FDA might even be anxiously waiting at this point. You have done an outstanding job. Believe it!

https://www.keytrudahcp.com/efficacy/?utm_source=bing&utm_medium=cpc&utm_campaign=Keytruda%20HCP_Pan-Tumor_Brand_Exact&utm_term=keytruda%20trials&utm_content=Clinical%20Data_Exact&&msclkid=3e7a1ca569031de0b82d7f426e8ba1b4&gclid=3e7a1ca569031de0b82d7f426e8ba1b4&gclsrc=3p.ds

Short squeeze in the news:

https://www.fool.com/investing/2023/02/09/this-short-squeeze-candidate-could-actually-pan-ou/?source=eptyholnk0000202&utm_source=yahoo-host&utm_medium=feed&utm_campaign=article

Check out the approved cancer indications for Ketruda. Why can't we get the same for neurological indications for our Blacamesine?

https://www.keytruda.com/how-d/

Scroll down to FDA-Approved Indications.

ADAS-Cog Test?

https://www.verywellhealth.com/alzheimers-disease-assessment-scale-98625

Time for us to step up and get approval.

Last month, Anavex Life Sciences reported positive topline data from a phase IIb/III study on its lead pipeline candidate ANAVEX 2-73 (blarcamesine) in AD indication. The ANAVEX 2-73-AD-004 study achieved its primary and key secondary endpoints. Data from the study showed that study participants who received ANAVEX 2-73 were 84% more likely to have improved cognition than those who were administered a placebo. Patients treated with ANAVEX 2-73 were 167% more likely to improve function than those receiving a placebo. The treatment also showed a statistically significant reduction in cognitive decline at the end of treatment by 45% compared with the placebo.

https://finance.yahoo.com/news/fda-rejects-accelerated-nod-lillys-175205484.html

The only discerning signal that consistently cuts through the noise, for me, is WGT. Just waiting for the rest of the world to find out about it.

Best Wishes to all for a healthy, happy and prosperous New Year!

Did you mean to say other “than”? Dumber “than”? Just asking. That’s ok though. It’s still clear where you are coming from. I have had dumber professors in my life. Maybe proper wording is above your pay grade.

God Bless you for posting that video. Thank you!

No thank you! Natural Immunity works fine for me. And as an added bonus, my NI will keep you safe as well.

Biogen seems more involved with population control than health care with all of the brain-swelling, brain-bleeeding drugs the fda allows them to usher to market. Any discussion of a partnership with biogen goes beyond insanity. They would sit on our disease- modifying medicine. We are no doubt witnessing a systemic breakdown of all systems within the U.S. Just look around.