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This isn’t your parents FDA. We are transitioning to a vaccine oriented medical system, IMO. It has only been a few short years that medicine ads now include potential side effects. Many of them seem horrendous, including death. What is that about? For me, after listening to side effects of some advertised drugs causes me to think, I wouldn’t take that. Maybe that’s the response that we are being conditioned to, so a vaccine would seem more preferable. Haven’t heard any vax side effects during ads. During Covid, you couldn’t board an airline if you were unvaxed. Canada gave a glimpse of other consequences. I am not anti-vax for those that want it. I prefer a pill. Will FDA approve 2-73 near-term? Hope so.
If “Cancer Drug” Keytruda can be approved by the FDA for numerous types of cancer, not withstanding a plethora of side effects, when will they approve a “CNS Drug” that succeeded in every Clinical Trial with minimal side effects. Presenting our case for 2-73, to the FDA might be a good start. At this stage of our development, I can’t see us seeking approval for Rett, then for Parkinson’s, then for Alzheimer’s Disease, then for Autism, then for MS, then for….ad infinitum. Come on Dr Missling, millions of your fellow men, women and children are waiting for you to step up. The FDA might even be anxiously waiting at this point. You have done an outstanding job. Believe it!
https://www.keytrudahcp.com/efficacy/?utm_source=bing&utm_medium=cpc&utm_campaign=Keytruda%20HCP_Pan-Tumor_Brand_Exact&utm_term=keytruda%20trials&utm_content=Clinical%20Data_Exact&&msclkid=3e7a1ca569031de0b82d7f426e8ba1b4&gclid=3e7a1ca569031de0b82d7f426e8ba1b4&gclsrc=3p.ds
Check out the approved cancer indications for Ketruda. Why can't we get the same for neurological indications for our Blacamesine?
https://www.keytruda.com/how-d/
Scroll down to FDA-Approved Indications.
Time for us to step up and get approval.
Last month, Anavex Life Sciences reported positive topline data from a phase IIb/III study on its lead pipeline candidate ANAVEX 2-73 (blarcamesine) in AD indication. The ANAVEX 2-73-AD-004 study achieved its primary and key secondary endpoints. Data from the study showed that study participants who received ANAVEX 2-73 were 84% more likely to have improved cognition than those who were administered a placebo. Patients treated with ANAVEX 2-73 were 167% more likely to improve function than those receiving a placebo. The treatment also showed a statistically significant reduction in cognitive decline at the end of treatment by 45% compared with the placebo.
https://finance.yahoo.com/news/fda-rejects-accelerated-nod-lillys-175205484.html
The only discerning signal that consistently cuts through the noise, for me, is WGT. Just waiting for the rest of the world to find out about it.
Best Wishes to all for a healthy, happy and prosperous New Year!
Did you mean to say other “than”? Dumber “than”? Just asking. That’s ok though. It’s still clear where you are coming from. I have had dumber professors in my life. Maybe proper wording is above your pay grade.
God Bless you for posting that video. Thank you!
No thank you! Natural Immunity works fine for me. And as an added bonus, my NI will keep you safe as well.
Biogen seems more involved with population control than health care with all of the brain-swelling, brain-bleeeding drugs the fda allows them to usher to market. Any discussion of a partnership with biogen goes beyond insanity. They would sit on our disease- modifying medicine. We are no doubt witnessing a systemic breakdown of all systems within the U.S. Just look around.
Elon Musk’s attack on big tech/gov collusion is admirable. Maybe he can do the same with the big pharma/gov apparent conflict of interest situation.
I sold my Roth shares Friday at 12. Just bought back at 8.50. Nice to accumulate more shares during this shtshow. WGT
Dr Missling did say he will be meeting with the FDA and will be aggressively seeking accelerated approval. I don’t remember if he said those words in the same sentence though. But he does need to become substantially more aggressive, IMO.
Cramer was one of AF’s mentors so I guess that goes for him to. Unfortunately, the shorts play by different rules. They operate in a different universe. Hopefully the wheel of life rule will kick in; Whatever you put on the wheel, be it good or be it bad, will come back to you. That’s the rule. The time for shorts to pay the price seems long overdue.
He may be on InvestorVillage:
https://www.investorvillage.com/smbd.asp?mb=9414&pt=m&category=A&Top=1
It might be too late in the game for partnerships. Why enter a partnership when they could own the whole ball of wax for a few dollars more? A 100% premium at this share price would only be just north of 2 billion dollars. We are severely, dangerously underpriced. Dr Missling needs to start talking this company up in a big way before outstanding results are announced, IMO.
Biogen has a shady history with partnerships. Look at Elan with Tecfidera and Idec with Rituxan. Both Elan and Idec got kicked to the curb as soon as the ink was dried on the partnership agreement. Be careful what you ask for.
Several years ago, when AVXL was trading around 20 or 30 cents per share, my son told a higher up in the company he worked for about AVXL. The guy loaded up and ended up paying for his three kids college education. Let’s hope something like that happens again.
I am fully confident that Dr Missling is engaged in providing Evidence-Based-Medicine. Unlike other companies, perhaps:
https://insulinresistance.org/index.php/jir/article/view/71
https://insulinresistance.org/index.php/jir/article/view/72
No time like the present!
RAM refers to Ram Selvaraju HC Wainwright, not your acronym version.
Yet a matter of time…
https://vetsolutions.org/
Uncontextualization doesn’t seem to be our problem. Dr Missling does an outstanding job identifying the actions of Anavex 2-73 and relating the effects of those actions on those suffering from a number of cns diseases. We have discovered enough positive results with minimal side effects to shift focus from R&D to commercialization, IMO. Greed is not in the cards for Dr Missling. No doubt, that is a good thing. It is time to begin to revolutionize medicine. Anavex 2-73 could be the beginning. It seems a no brainer, at this point, that we need a big pharma partner to get this to market, IMO.
Maybe this has been posted already. Maybe this will help the amyloid folks change their focus.
https://www.health.harvard.edu/mens-health/erectile-dysfunction-drug-may-lower-alzheimers-risk
The Reddit Wallstreetbets community has us in focus for August. Hedge funds are building interest. If this does drop below $3 (not likely, IMO) it will be a gift and an opportunity for believers to double down on their “investment” here.
https://finance.yahoo.com/news/amtd-digital-9-other-stocks-131528581.html
Seems like J&J has been reading our mail. They seem to be following in our footsteps. Hopefully this will incentivize Dr Missling to set this rocket in motion. We may have this but it seems J&J is in hot pursuit.
George’s link
https://www.fiercebiotech.com/biotech/hitting-rd-sweet-spot-how-jjs-janssen-approaching-race-next-alzheimers-therapy
Here is a link to the guy he interviewed, Chris Bedford, The Federalist:
https://thefederalist.com/2022/07/28/inside-the-corrupt-world-of-alzheimers-science-and-what-its-failure-means-for-all-settled-science/
Several years ago, the concept of Precision Medicine came on the scene. It seemed a sure way to introduce another concept especially to the pharmaceutical industry, ethics. Our CEO is still onboard with that and may one day receive a well deserved noble prize while many of his peers are currently filling their pockets with blood money from the crap science they are profiting from. Missling once said he believed it was unethical to prescribe medicines that precision medicine shows won’t benefit certain people. We seem to be the only company blazing this trail. There’s enough evidence out there to show that many companies have have zero interest in Precision Medicine. Our day will come.
And the beat goes on…
FDA agrees to review ALS treatment from Biogen $BIIB, despite inconclusive clinical trial results https://t.co/nFT1RTxcwo Another ALS plot twist $AMLX
— Adam Feuerstein ✡️ (@adamfeuerstein) July 26, 2022
Something will surely be tried, made up, etc to salvage their work.
I wonder what Biogen’s story will be.
Couldbebetter,
Maybe this can be a starting point:
https://www.fda.gov/about-fda/center-drug-evaluation-and-research-cder/physician-request-single-patient-ind-compassionate-or-emergency-use
Upon laboratory confirmation of the modeling studies, Anavex2-73 could change the way we treat or see Alzheimer’s disease. It could restore memory function and completely change the trajectory of disease progression. As a matter of fact, it should work on other diseases as well such as Parkinson’s, ALS, Fragile X syndrome, Rett, and possibly others. As for the ongoing trials, the results could be so spectacular that we would have never expected!)
https://www.biotechtoinvest.com/research/2022/5/15/the-answer-was-here-all-the-time-why-anavex2-73-can-stop-alzheimers-disease
Maybe not so crazy.
I owned stock in a company that was trading at $35. When it got FDA approval, it went to $200 in short order. Soon it did a 3:1 forward stock split. It continued to increase in sp to the $200 area. Soon, it forward split again. This time 2:1. So the $1200 sp isn’t that crazy, IMO.
Do the math if someone owns 1000 shares of AVXL
Years later I sold for $470
Best of luck to you!
That goes away. My wife used to do the same thing. Not anymore. I think she believes WGT. Best of luck!
Just found this in my inbox mail. Not sure if anyone else has posted about AF’s new gig. It requires a subscription that I don’t have.
https://www.statnews.com/2022/07/01/not-so-happy-midyear-biotech-ceos-best-and-worst-and-a-hopeful-sign-of-a-turnaround/
CEO of Teale drones coming up on Fox Business Now!
Waiting for AD day. PD day would be nice but I think Rett Syndrome will get us to market first.