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Get the Rett results out and file the dang NDA already.
I think $200-$250 per share by sometime in 2025 would happen if AD indication approved
Yes, but until an NDA is filed, the market doesn't believe this. An NDA would make the market have to consider the possibility.
did you see Jesse Brodkin ask the first question at the Dec presentation? He is a short tool.
What I dont get is what is to be gained at this point from being short. Geez they have squeezed all the juice from this orange. From mid $20s to $7. Why dont they go find another biotech to destroy?
At this point, if an NDA were filed, the stock could double overnight. Or if a big partnership was announced. So why stay short and give iti all back like us foolish longs did? for what, another dollar maybe? I dont get it.
How long do you think it takes to write an NDA for a drug with a new MOA?
The quick answer is less than the years that much of this data has been in AVXL's hands.
My impression is that these things take 3-6 months of intensive effort from scratch, but we aren't starting from scratch, are we?
Preservation of brain volume in alz patients is BIG.
As long as the brain is preserved, neuroplasticity can rewire the house and keep the lights on in all the rooms.
And it is physical and measurable.
Plus the brain bleed mabs dont work in this area, do the opposite.
I'd take either partner ($1 billion cash plus percentage) or NDA. Missling has always said approval ("NDA") before partner, so what you are suggesting goes against Missling canon. Just get something done already.
How about actually submitting the NDAs?
A Rett NDA or Alz NDA is what is needed to turn this around.
Some big shareholder has decided that WDGT and is getting out. Over 1 million shares sold as losses are cut.
Makes sense if WDGT. And the seller definitely feels WDGT.
I did get clarity on the ADL - significant end point and why it wasn't provided -
OK, why wasn't it provided?
A $5 billion offer would take this company out.
It could happen if Rett results are clear and unambiguously good.
Market attributes little value to alz ans sees it as 4-5 years away. Lack of movement on yesterdays news makes this clear.
I'm talking about upcoming Rett results and what is needed to move this stock out of the gutter. Clear unvarnished Rett efficacy and NDA is needed.
Dead money until an NDA is filed.
Pretty clear now that Rett results need to be heroic and followed up with an immediate NDA.
Alz approval will only be made on a repositioning of the drug after Rett approval.
Years to go unless Rett results are astounding.
Agree, where's the beef?
Don worry, they will hit all the milestones (Rett Data, full alz data, PD trial start)
just like they did in 2022.
LOL. A very fast model T, if it is a model V
less than 3 months from now. Remember FULL DATA SET for both Rett and AD - right ?
AD data should have been ready months ago.
Prefer to see a Rett NDA this fall above all else
Like watching glaciers melt
Godot, is that you?
It's showtime!
What makes the day after Labor Day a great day to present the Rett TLD?
People are back from summer vacations and starting new work for the fall.
FWIW - Rett Syndrome Awareness Month is recognized globally in October.
So what? why give the short another month to melt the stock price. Besides that would be predictable, and Missling doesnt want to be predictable. And this would give the Rett people "somethng to talk about" right up to and through OCtober.
Next Tuesday would be a great day to present Rett TLD
What do you think that means?
Beat down as no news gives short a free hand on Thursday and Friday. Cmon Dr. M, surprise them with a Thursday announcement.
Seems we go up the first half of the week, down the back half
The Last Remake of Beau Geste
jest in time for the weekend, a movie classic with marty feldman
T
Nice find: straight from the mouth of the FDA
Wow, negative reunion today.
All the old names back to try to talk down AVXL.
All we need is the Grim Reaper guy to complete the ensemble.
I guess someone has a big short position to cover and is frustrated that the stock price remains on the road to recovery.
must be scary to be short and knowing that top line Rett data or more alz data could appear at any time, and Dr. M has assured us there will be NO warning when he drops the bomb on the shorts.
All the advanced degree holders on Wall Street don't understand AVXL at all. So much for degrees.
My take on 1 and 3 year chart is that
if we can close up this week, we could be at $12-13 in a blink.
Seems like the pressure is building.
Well, maybe one ignore would enhance it. 😆
A bomb with shorty's name on it is ticking.
When will it go off? No one knows.
Better cover now while you can
would be great to see some news of substance, such as Rett TLD, on Monday or Tuesday.
Would cement the upward momentum.