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very good point
NEXT 2 WEEKS CATALYSTS :
1. End point changes on US Gov website BIG
2. NWBO PR end points changed and accepted by FDA HUGE
3. END POINTS MET PR
4. Journal publication including new information HUGE
5. ASCO presentation
6. ASCO New information
7. MHRA. application to be made ( or already made )
8. BLA to be made ( or already made )
9. Statement on buy out interest received ( as requested by Rago on Twitter )
Thanks ! and sorry I completely missed this
VuBru - thanks for confirming this so why do you think we have not changed the endpoints now there`s been a soft release of data and a PR confirming endpoint charge would rewrite this weeks sorry script ?
OK thanks kind of what I thought, so I believe 100% if North West change the endpoints and PR that , following this weeks data however shoddy the soft relase was , we would trade $5 immediately
Many thanks
A question of huge importance :
Clinical Trial Websites .
EU UK , regulators manage their sites and upon acceptance of our revised SAP updated the new accepted end points accordingly
US FDA , apparently the sponsor is responsible for updating the website however the FDA do not give an official response to end point change submissions , however we seem to collectively accept that if the did not accept the changes they notify the company within 90 days .
We know this did not happen because the company would be 100% bound to PR this negative response to the application to change end points as it was the company that put the application into the public domain .
SO... when does tacit acceptance by the FDA become overt acceptance.?
Right now as we speak anyone cross referencing the slides with the FDA site will see at best confusion and at worst a failed primary end point trial outcome thus negating almost any chance of them buying in .
Does anyone please know the answer ??
Thanks in advance
AE , sure I certainly accept that but that wasnt my question ... when does tacet acceptance become overt , when do they say yes we accepted it ?
A question of huge importance :
Clinical Trial Websites .
EU UK , regulators manage their sites and upon acceptance of our revised SAP updated the new accepted end points accordingly
US FDA , apparently the sponsor is responsible for updating the website however the FDA do not give an official response to end point change submissions , however we seem to collectively accept that if the did not accept the changes they notify the company within 90 days .
We know this did not happen because the company would be 100% bound to PR this negative response to the application to change end points as it was the company that put the application into the public domain .
SO... when does tacit acceptance by the FDA become overt acceptance.?
Right now as we speak anyone cross referencing the slides with the FDA site will see at best confusion and at worst a failed primary end point trial outcome thus negating almost any chance of them buying in .
Does anyone please know the answer ??
Thanks in advance
Many thanks RHR
MI Dendream - Ive called Elsvier ( Annals owners ) and got nowhere .
Can anyone please confirm :
1.the next publication date &
2.if the AoO publish ad hoc , as and when as well as their periodicals
....Please
NIce gap to $1.82 ...
Very good indeed -Thank you
The rules are simple. You have to be making an official material PR to news services that you show to the exchange first in order for them to halt trading.
We wouldn’t/ couldn’t PR they wouldn’t halt trading.
The fact ‘ Dave ‘ didn’t know that is worrying.
MHRA guarantee a decision within 150 calendar days .
If we PR the application has gone in we will be back closing green everyday again ...
Excellent post Merv , I agree with literally every line you have written.
Thanks Flipper TO GET BACK ON TRACK LINDA P MUST :
1.Change the endpoints on the US clinicaltrial.gov site immediately
2.Get the journal out this weekend
3.Announce MHRA application has been made
She accepted the embargo and yet went ahead with the NYAS , but I assume she saw it as a way of lighting the blue touch paper , however hind site is an exact science and it was seriously misjudged.
100% WE WILL BE BOUGHT OUT
INCREDIBLE nGBM. STAGGERINGLY GOOD rGBM
BRILLIANT RESULTS.
Thank you.... and is it the Data release or not ???
where does it say that ?? im on the site now. ..
PR at 8.15am New York Time I reckon ...
Correct... all equities indexes will be green today so no head wind for our pps
10q OUT
...such a shame she can’t present her life’s work ..... she’ll just have
to make do with a Nobel Prize..
Linda L has Covid … confirmed
100% normal for Biotec / small cap to finish red night before data. Seen it more often than not …
All we need tomorrow is one institutional buyer , just one and should data be positive and the narrative up beat then there’s no reason we don’t have multiple tutes buying ….which will assure us of a huge spike tomorrow
Its all about the narrative tomorrow .... the bare bones PR will be a short order price range as per my chart below ... but positive talk about rGBM etc, current ongoing trials , JV's etc will all add to the short order price, and of course ....will we find out tomorrow what the home run was...
After all this time they must have a surprise up their sleeve`s ..
Yes , I reckon Merck will have agreed some form of ` first look / first refusal ` situation
Yes just depends which broker dealer your broker uses.
GermanCol - very good work indeed
Thanks you
old list vs new list , look again ... anyway who cares
Its both
Available to borrow ....
200 shares ..
Recent Data
Fee Available Updated
14.5 % 200 2022-05-04 15:45:03
14.5 % 200 2022-05-04 15:30:03
14.5 % 200 2022-05-04 15:15:04
11.9 % 200 2022-05-04 15:00:04
11.9 % 200 2022-05-04 14:45:03
11.9 % 200 2022-05-04 14:30:03
11.9 % 300 2022-05-04 14:15:04
8.0 % 300 2022-05-04 14:00:03
8.0 % 200 2022-05-04 13:45:03
8.0 % 200 2022-05-04 13:30:03
8.0 % 200 2022-05-04 13:15:04
8.0 % 600 2022-05-04 13:00:03
8.0 % 600 2022-05-04 12:45:03
8.0 % 600 2022-05-04 12:30:03
8.0 % 600 2022-05-04 12:15:03
8.0 % 4,000 2022-05-04 12:00:03
6.4 % 35,000 2022-05-03 16:45:03
6.4 % 35,000 2022-05-03 16:30:05
6.4 % 35,000 2022-05-03 16:15:03
4.8 % 100,000 2022-05-02 12:30:03
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4.9 % 100,000 2022-05-02 12:00:03
4.9 % 100,000 2022-05-02 11:45:03
6.1 % 200,000 2022-04-29 16:45:05
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6.1 % 200,000 2022-04-29 15:45:03
6.1 % 200,000 2022-04-29 15:30:03
6.1 % 200,000 2022-04-29 15:15:03
6.1 % 200,000 2022-04-29 15:00:03
6.1 % 200,000 2022-04-29 14:45:04
6.1 % 200,000 2022-04-29 14:30:03
6.1 % 200,000 2022-04-29 14:15:03
6.1 % 200,000 2022-04-29 14:00:03
6.1 % 200,000 2022-04-29 13:45:03
6.1 % 200,000 2022-04-29 13:30:03