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having been fortunate to fly once in a private jet and too many times commercial.
flying private is just so much better.
walk into the hangar, pilot or copilot takes your bag.
no checking luggage or strip searches lol.
breakfast drinks lunch etc. bathroom was quite nice..
land in subzero weather, emerge from jet into heated vehicle
drive 15 minutes to the rink..
having a friend with a netjets account .. 2 thumbs up
Not true at all
Scotty knows exactly how to get this accomplished
He is a message board expert on all things NWBO
We have all read SOS in the past , most of his stuff with a grain of salt attached.
Look past the messenger
Read is for what it is
It’s a thought out passageway to the finish line
Whether one chooses to believe it with ROSE COLORED GLASSES, BLUBLOCKERS, RAYBANS, or those hideous glasses , name escapes me marketed to the elderly that fit over regular glasses
I would just say NWBO is working in conjunction with 4 SAPS/ regulatory agencies and has been these past few months interacting on a daily weekly basis FINALIZING THE SAPS
let’s see what soon materializes
SOS opinion is just as valid as yours , probably more valid because he is actually linking coherent thought processes together.
Just because he may have been wrong once before does not invalidate every future post one makes. Otherwise we would not have a board
I have been wrong on this board before , well just once, but many have been wrong . Incoherent , thoughtless Nd are permitted to post nonsense like it’s a FACT.
Everyone is free to believe whatever they wish to believe - fact fiction or somewhere in between
I have a healthy amount of skepticism for management
Who really knows what to believe
What I do believe is the science to be sound - after all this time
I think we are close / how close / subject to debate as nauseum on this board
At the end of the day, I think the drug GETS APPROVAL, by EOY 2020
Between now and then everyone is right and wrong and let free speech reign
What is the best way for LP to navigate the labyrinth of misfortune dealt to her over the years - I am just hopeful she makes it to the finish line for the sake of the GBM patients , all future cancer patients and those like myself o have invested hard earned money into this concept
Everything done on this MB is conjecture
U can choose to believe it or not!!!
Free speech and free country
I draw my own conclusions based on my own research and knowledge extended by truthful meme era of this board
Not the wordsmiths who want to parse words with intentional falsehoods
Flipper
I get what your saying
Why believe him now when he was wrong before ??
What are u so hung up on
We are knocking on the door - I expect real news PR from NWBO in 30-60 days
Why are you so upset
No we conjectured that the endpoints have changed
Subtle difference
It’s not a FACT but it makes the most sense because median PFS and mOS were the benchmarks then
FDA hates subgroups, now they love subgroups data because it’s highly specific to a patient group and gives said patient best chance at survival and not wasting cost of therapy on job responders
Larry asked the question of DI SUCH THAT he could surmise that m PFS & mOS are not the priority now
They will be reported but they don’t jive with the 15-40% ORR in the LONG TAIL
TAKE OFF THE BLINDERS and listen or see what info is being given
They didn’t give SOS anything that hasn’t been conjectured here a million times
He just asked the same questions I did
He got virtually the same answers I did
SOS asked questions IF THIS THEN THAT HAPPENS
ASK enough of those questions in and out of sequence to connect all your dots
You are insinuating DI is doing something illegal
He is not
But u keep repeating it -THATS NOT TRUE
Also need to remember we have a few subgroups of patients -
methylated and unmethylated, in SOC and TX GROUP
And in the crossovers — progressors cs pseudo progressors
Does any one subgroup methyl or unmethylated show more likely in progressor or pseudo etc
Many questions to answer
Or just take the raw data throw it in the air and say hey we got 20-25% of all patients LONG TAIL
DO A MIC DROP and let the data stand on its own
Larry connected the dots expertly just like we do here-
except he took everything as a positive and not a negative
Which is why the trial has taken so long - I look at this as a unique opportunity to get in ahead of the herd and own before anyone else knows about this
Many people here own 10-50-100k shares more than enough to make large sums of cash upon unblinding and , partnership or buyout .
This stock truly has the ability to make life changing wealth for those on this board
What is the true value of this technology across any and all solid tumors if it eventually proves to work
This company could become the AAPL GOOG AMZN of the biotech industry in 3-5 years
Yes it could go from 100m to a 1 Trillion dollar company or if it fails be worth nothing
Druggie
Yes 99% on Larry Smith article has been hashed out in parts over many years
It’s fairly obvious this info can directly from NWBO and was compiled recently
It confirms many of the topics I addressed with DI in calls the past few weeks
Does it break any new ground
Yes - removes the facts that the initial trial endpoints will be changed based on new knowledge
Median survival and PFS are muted now because median is the halfway point and we are realistically dealing with 15-40% which is still a vast improvement over SOC DATA which LARRY lays out
Does this give me more basis to own NWBO - YES
DID I ALREADY KNOW MUCH OF THIS - yes
I know all this because of the chatter on this board from great contributors
Doc logic, doc Bala , iwasadiver, mi Dendream, senti, flipper, maverick, marzan , et al who all share knowledge and conjecture in a way beneficial to all
The article basically answered most every question
Except the reason for the hold even though it laid out the reasons for continuing the trial -LONG TAIL
WHAT EXACTLY DO U WANT THEM TO SAY
They can’t give a time frame for the reaction time of the SAP by four diff countries
Just that obviously they are doing everything in their power to expedite
SOC crossovers should not be the issue except they didn’t get to count them as deceased at X time from progression
That is a mistake in classification likely with the original SAP
It’s safe to say I have less invested here than many
My average cost is 0.27
So if when good news occurs
I will do just fine
I did accumulate
3X my original position
So even a low ball offer will make me quite comfortable
An offer said to be enough to get Linda to sell would allow my children a very comfortable life
IBIO
NOT familiar with this message board
Then that would be fraudulent / maybe someone misunderstood him
He is a PHARM D
Which is a DOCTOR OF PHARMACY
MAYBE someone misinterpreted ???
I agree - but I believe his creditability is already in question
He is just a pumper
BSB I don’t ever recall CHRIS saying he was an MD
His twitter profile in the past says he is a pharmacist
I can’t access twitter at work/ darn IT filters
chris is a pumper imo with no more or less creditability than anyone else on the board
Let’s get to the first mountain top before we rule the world
Right now we can’t even ski on a green slope and u want a double black diamond
Pharmacists rank annually 1-2 in most trusted professions so NO, being a pharmacist would not make him more prone to lying — if he was a stock analyst or a POLY PSY MAJOR- then he would be considered a lying liar
Not true at all- a company is only worth what someone else is willing to pay at the time u want to sell
My home is 400k- but we are a distressed seller in a bad luxury home market in the Midwest
So the best we can do is one offer at 330k
Can’t afford to wait for other bids
If LP takes 5-10B she is perfectly within here rights to bring that offer to shareholders or wait for further proof of concept to get a higher bid
The problem is when You pull out progressors and pseudos in those subgroups u might just reduce the stats probability in a negative way
Hence why they are rewriting the SAPS to attempt to account for ALL the irregularities and confoundment In he data
Wow, JR
u have repeated this same post for a week. I hope u are using cut n paste and not free hand typing this out
We expect the data to be positive & that assumes that what has been said about the top 100 PTS survival data.
We have real data not projections and extrapolations of KAPLAN MEYER
what we really need is an explanation of the halt of 2015 and why we needed to extend 4 more years ??
I should not complain as this setback gave me an opportunity to invest here again and I expect to do quite well very soon
I think once topline is announced —
it starts the cascade of news
Unblind -
Gather data breakout above 0.40
Release topline data to public $1-2
Partnership announced $5-8
Direct D trial announces start date $5-8
News Years Eve ??????????????????
New Years Day ????????????
Nice article
Bio I still can’t understand why people want to attack this company.
These posters who claim fraud, deceit, outright lying to shareholders is just plain wrong and disengenuous.
We stand on the precipice of something truly unique that can save lives.
I am all for point counterpoint and free exchange of ideas, but these coordinated attacks on the integrity of the officers of and the company as a whole is downright disgusting.
They will when they partner with NWBO
Big pharma could run concurrentl pivotal trials in different solid tumors and be done within 30 months
Let’s be realistic - they are waiting on FDA and Europe
IMO IF they have positive feedback on either one of these two, the meter starts on the other to be on board or at least not negative. Then unblind and data lock will occur
This is the final check before the ship sails. Anchors up and shove off mates!!!!
No he didn’t say under 30 days
When u talk to DI, u ask questions around a process
If this first , then X , how long is something like this , then how long is X
How long is Y ,
What has to be done in order unblind / DATA LOCK.
How long to calculate the data once u unblind
If Europe SAP says we GOOD
Would you wait on FDA, if so how long , depends on how the dialogue with FDA has progressed
If Canada says good and no one else ?? Probably wait
Many contingencies and WHAT IFS
He always just changes his addiction or focus
He will also become a new father soon
Let’s hope THAT becomes his new purpose and not a new drug
Yes whoever u speak with draws a picture of what can happen and a potential time frame
This differs from the past imo in that we now think we know the end is truly near
Well I think so. Having seen more than a few drugs reach the finish line
My only fear is making stat sig with such a limited number of patients even with the long tail
That’s where trust n faith come into play
BTW. I do understand what u say
Oh ok bc you don’t have a spare 20-30 minutes
I spend as much time as I can with my sons / daughters etc
U always have time it’s what u make of it
Just like u, I have evaluated my investment and it’s potential for success
The drug will succeed , for me it is WHEN
Everyone is allowed to interpret what they wish from 10q or a conversation with an officer of a company
What can’t be denied is the that patients who received DCVAX are living significantly longer than patients on the SOC for this trial and historical SOC in other trials
All the other stuff is a diversion from the goal
The company has to rewrite a SAP to attempt to explain what happened with crossover patients , and other subgroup PTS methylated , unmethylated , SOC , SOC crossover / methylated crossovers unmethylated crossovers
These subgroups on their own can’t yield a stat sig for anyone group
But the totality of the stats for OS is likely what the SAP will try to explain
Considering that they have struggled to raise money hopefully the unblind occurs soon so they don’t have to keep diluting 10-20m shares at a time
Marzan thoughts on $AMRN Maybe u can finance the next bandaid for Linda
ADAM n Matthew were wolves in sheep clothing yesterday saying all good on VASCEPA then today their true colors came out
They will be wrong on DCVAX also very soon
I don’t believe anything said in a phone call would rise to the level of a PR
WE ALL wish they pumped out weekly updates but that’s not prudent
Pretty much every small cap i own puts out PR AND closes down that day
I don’t require a lot of hand holding
I have a good idea what i own
Just have to hope that. NWBO has enough smart people in the room when it’s time
Mani —- I spoke with DI also this week
I concur with everything MHILL said in his post.
And other nuggets he told me
I didn’t post everything he said
But I posted enough
I believe we are very close to data lock and unblind
Under 90 days for sure and probably less than 30
JMHO
Druggie