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Most recent ORAL MUCOSITIS deal:
Agree Mack. It has been an amazing 5 years as I've watched this company go from nothing to now having an unbelievable arsenal of first in class drugs that will ALL become blockbusters. IMO.
Today is November 1st. We should have 3 sets of data for phase 2's on 3 separate possible blockbuster drugs within the next 3 months
JUST AROUND THE CORNER = phase 2 OM data in November/December.
K phase 2 Ovarian update in November/December
Prurisol phase 2b completion in December and data shortly after!
To me in bio world. That is a blink.
Looks like it budged to me!!! Where are those .60's?????? Bahahaaa
IPIX - Look at the board toady folks. See what is going on.
Once the first partnership is announced, the fact the company is showing they are adding so many more indications with HUGE potential will pay off. Currently the negative bandwagon is preying off the fact we are funding ourselves and therefore downplaying these new indications.
So this is what WILL happen IMO: After one of the PHASE 2's that are about to release data, the company will partner. From discussions with people invested here and some others, the vetting process for a partner is actually on IPIX's shoulders and which direction they want to go. The MGMT will not tell us until the deal is done. Obviously.
I am hoping they find the "RIGHT" partner to take us through many of the indications and trials who will be that "PARTNER" for life. Adding unlimited funds and resources including staff to move Brilacidin through the dozens of possible indications as it is a low hanging fruit and can make Billions upon Billions in the indications that they are currently testing. I am also hoping they find the "RIGHT" partner for life and the deal will be heavily loaded with MILESTONES. I am not so concerned with UPFRONTS as long as our PARTNER pays and supplies staff to assist with all the trials and formulations. I believe that Dr. M and B know we have a unique and safe arsenal and they should roll the dice by requesting huge milestone payments for each indication and phase and formulation advancement.
If they go the milestone heavy partnership route, we as IPIX shareholders could have years upon years of news and catalysts taking this to a ceiling that does not exist.
Just take a minute to think of all the possible indications that IPIX has hinted at, and if we had unlimited resources and help we can have a dozen or so trials going at once and each having significant milestone payments as we pass the test. Every month we can have PR's stating another milestone for IPIX and Pfizer pays 100 million and another 100 million and another 100 million etc...
I believe the right PARTNER who fits us well is already on board and the deal is being inked based on these phase 2's and we should see who that is shortly.
Leo knows we need help and is looking for the right fit. IMO
All of this is my opinion and not fact. Good to hear more about HS and Acne today.
News!!! Prurisol on SCHEDULE to end in December!!!!
If there was something WRONG the trial would have stopped. He does not have data. Period. There is nothing wrong. 100%. Nothing
Yeah, I mean what would you like to hear? I don't get what all the negative Prurisol are about? How the hell is P looking scary? The company cannot promote or pump results because they don't have them. It's a POWERED phase 2b. Double blind
IPIX would get in trouble to say anything because they don't know.
They could mention the facts again where the phase 2a actually compared nicely and actually out performed Otezla at the same juncture in phase 2a data with the 200 mg arm
But again. This board is full of you know what.
Great to hear P is on schedule to conclude in December.
I'm not seeing that? Looks like you are lying once again. Please stay on topic and stop lying about IPIX.
So we bought the B franchise. Hired a top tier President and SUCCESSFULLY completed 5 trials and have data pending for 3 trials this quarter! All while extending the OS to 137 million. Same share price folks!!!!!! You think we are undervalued here.....?????? I'd SAY SO!$$$$$$$
Greatest Post of the Year right here!!!
All new comers...read this! In 2012 the company had less than 100,000 in cash. Zero financing agreements. The first HUMAN CLINICAL trial commenced in their history. About 90+ million shares OS. Only Prurisol and Kevetrin. Share price was around .70.
Ummmmmm.....now look at this progress:
IPIX Clinical Trial Timelines
2012
1. Kevetrin (Phase 1)
2013
1. Kevetrin (Phase 1)
2014
1. Kevetrin (Phase 1)
2. Brilacidin-ABSSSI (Phase 2b)
3. Prurisol (Phase 1)
2015
1. Kevetrin (Phase 1)
2. Brilacidin-ABSSSI (Phase 2b, Successful)
3. Prurisol (Phase 1, Successful)
4. Brilacidin-OM (Phase 2)
5. Prurisol (Phase 2a)
2016
1. Kevetrin (Phase 1, Successful)
2. Brilacidin-ABSSSI (Phase 2b, Successful)
3. Prurisol (Phase 1, Successful)
4. Brilacidin-OM (Phase 2)
5. Prurisol (Phase 2a, Successful)
6. Brilacidin-UP (Phase 2 POC)
7. Prurisol (Phase 2b)
2017
1. Kevetrin (Phase 1, Successful)
2. Brilacidin-ABSSSI (Phase 2b, Successful)
3. Prurisol (Phase 1, Successful)
4. Brilacidin-OM (Phase 2)
5. Prurisol (Phase 2a, Successful)
6. Brilacidin-UP (Phase 2 POC, Successful)
7. Prurisol (Phase 2b)
8. Kevetrin-OC (Phase 2a)
https://clinicaltrials.gov/ct2/results?term=cellceutix&Search=Search
November to REMEMBER! Only 1 day away......IPIX will not be held down.
Great INFO!!! Thx
B-OM results will keep this train rolling. Any time now.
Just a reminder, there are no approved PREVENTATIVE drugs for OM. Go through the past trials for OM, it is all about lessening the duration. Big difference on our protocol and primary measure.
I'm expecting to see 80% prevention. That would make this drug for OM alone worth billions after a 5-10x valuation after first year on market.
Is that 400K volume?!? Booyaaa.
BOM. Interim. 2 of 9 patients developed SOM
7 of 10 developed SOM in the placebo arm.
That is a big difference. HUGE!
Good volume. Power hour approaching.
Agree. If you go through recent OM trials. All are pretty much for DURATION of SOM. We changed and our primary is prevention!!! If we stick a number of preventing OM around 80-88% of the time! It will be new standard of care with every head and neck cancer patient going thru chemo radiation treatment.
Breakthrough will be granted and who knows if the FDA will see all other B data and allow to market early. Great time to be here at IPIX.
BOOM!!!
Winding Tight!!!! 835 x 84. Boom time!!!
Each investor has their own agenda. You should definitely know that :)
This guy is retired. Has I think 3 houses, and is a Harvard grad. Maybe for him, he wants to see a "guarantee" before he jumps back in? Maybe a lot of intelligent and wealthy people are doing the same thing? Idk. I'm just expressing to my friends here that I know not just one but several big retail investors and all have plans on returning. This one that I recently spoke to, plans on for sure jumping in prior to P. Maybe psoriasis hits home with him? He's not my best friend, so I don't ask...I just screw with him saying I'll be more wealthy than him by the time P results come out. Lol. His loss .... not mine.
We need the right media outlets to take this there. I know several 100K previous investors that are out and will jump in when they see this starting to steam.
I spoke to one last week screwing with him and he said he may or may not enter prior to OM. He will 100% enter prior to Prurisol though. He believes that is the big one. Even if the stock is at 2.00 he will still put his 100K in because as we both agree this is pre REGN style. He thinks 10-20 billion market cap will come if everything continues on the path they are on.
Great! Welcome aboard! The price you just bought at was the price in 2012 when there was no financing - zero cash and zero human clinical trials. And no Brilacidin.
Today we have 8 human clinical trials.
1 sitting ready for phase 3
2 about to drop top line data for phase 2's which can move them to phase 3
All for different indications in HUGE MARKETS
I'd say - you just bought a golden ticket
Congrats.
Correct. Here is the drug info that actually took the company into bankruptcy.
http://www.medkoo.com/products/7870
We simply need to get the heck out of this rut! The anticipation of every move imo is not helping this company. I am not one to suggest manipulation or tricks from the company but I kind of am. For example: every PR is absorbed by the retail community due to how transparent IPIX is. I love how open and transparent they are. DI NOT GET ME WRONG....They tell us when some one was last dosed and when the final followup is and etc....
I say! Let's go a different route: i.e. Kevetrin.
Let's have the company not say a word! No mention in any PR since the start. No mention cohort one is done. No mention what the committee thought. No mention of moving to cohort 2. No mention of a clinical site closing because recruitment is complete.....etc.....
Hopefully they just drop a bomb one day including recist data that can make any bio jump $20 in a day because the tumor has completely shrunk. And all bio markers were observed as BP wanted to see....
Now. That is when this $hit will get crazy. We need a Kershaw type curveball. IMO.
I've hit the whiskey early. My apologies.
What is good side of decent? In your opinion. Please
It is SCARY stuff. My HAY day was in the 80's and 90's and I don't mean to sound gross, but I never thought oral sex would lead to a death sentence later in my life. Some other articles I have read are saying it's like a 7 FOLD increase in head and neck cancer for men. By 2020 men with head and neck cancer will be at MUCH higher rates due to HPV than the cervical cancers for women.
So in regards to IPIX, this is a big deal if B-OM becomes the standard in prevention. We are looking at HUGE increase about to come and already started to show - hence all the coverage lately on this disease.
I wish everyone the best here - health wise. And longs financial wise.
Here is the video I found about the other cancer therapy that was on Nightly News last night:
https://www.yahoo.com/news/experimental-treatment-could-help-advanced-162700802.html
https://www.nbcnews.com/health/health-news/silent-epidemic-cancer-spreading-among-men-n811466
Crazy stuff. I also saw on Nightly News something about a new cancer therapy in trials that kills rare cancers that target a specific gene like 76% of the time. I'm trying to find the link.
lol. Same here
I understand Gov. but everything you say is not in Leo's control. No matter who owned B or K or P, the trials take time. Even if we had a partner, the data will come when it comes. They may have more influence with the FDA but it would be minimal imo to tie to market.
I understand your frustrations, but today's news was great. We OFFICIALLY have marked the date we are OFFICIALLY moving forward on plans to add Crohns and UC under the B umbrella. It's official. They have requested a meeting with the FDA. In bio that is something. Not just an empty PR. IMO.
If there is no partner by early next year I will be disappointed. I'm hoping by the time I return in late Feb there is some agreement in place. It all depends on the data readouts though. If P comes back at 55% PASI 75... ummmm I would imagine the bidding would be intense OVERNIGHT. If it's 25% PASI 75. We may need to wait.
Competition on bidding is what creates a fast moving deal process. If only one BP is involved a deal could take years. IMO.
IMO. And just my gut: IPIX is keeping this K trial under wraps so it will blindside a lot of people. I'm very excited to see this OC trials data. I am probably wrong about the blindside, but we will find out in the next 2 months.
Gov- bc if he took a deal now it could take away 10's of 100's of millions in upfronts. He has always said - after phase 2 is the time to sign on the dotted line. He has made it clear that 2017 is the time they are focused on partnerships. We brought on Dr B to assist with this for 2017.
If he inked a small deal. How many lawsuits would this company face.
3 phase 2 trials are set to release data in the next 3 months. One could be as soon as next week for all we know.
Hang in there. We are close than ever. IMO.
Awesome Cable!!! Thanks for sharing.
Epic Run!!! IMO. This crap share price in no way reflects the pipeline or the Mgmt. let's GO!!!!!
Great bold points. I did not read that.
It's good he sticks that in there. Subtle but good to hear. Great info today and good to hear they requested a meeting with the FDA.
Even better to go Oral for crohns and UC. The value there is unmatched.
I'm sure the optimized gel or foam is underway too for UP
Great news.
They are dosing 3xs a week now at 350mg/m2. Remember they started at 10mg/m2. Only once a week too. Went up to. 20. And then 30. Etc.....
We saw a tumor disappear.
Now we are dosing 250 and 350 ---3xs a week. I am not sure why people are not getting excited either. I'm jumping out my shin. It's like everyone on iHub forgot the name Kevetrin.
Soon it will return and we will rejoice.
A imo.
I agree. We just need one deal. It could be for 1 million upfront for all I care with good milestones. It would start the fire.
All we need is validation. But let's get real. If these trials produce what we have seen prior...the offer will be much HIGHER. Starting this week we start the data watch. It can be delivered at anytime
I don't think you understand "K"s MOA...or ATLEAST the moa that BP is hoping to see in this phase 2 trial. Oncology drugs are the big ticket drugs for BP. If K pans out in this trial I can easily see a collaboration because we need help exploring the MANY cancer types that K can have a positive effect on. No to mention exploring combo trials.
Repeat: BP has designed this phase 2 trial.
I have no clue what will happen or which drug may fall first into BPs hand. I am confident we partner soon
Does anyone know if IPIX gets data sets throughout the trial. Or does the CRO crunch the numbers and is all data released all at once or is much of the data already crunched? Any insight is much appreciated