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Appeal for reversal of denial ...successful.... somethings happening things are getting easier doors are opening - my gestalt says we are moving forward ...
Interesting - the INsurnace that has been giving the most resistance now poses question about presence of CAD - they are clueless to DM2 + two risk factors as an indication but at least they understand one indication now other than trigs >500 -
when you think about this you realize how insane our health care system is - so for over a year now, a humble rural family physician has been attempting to educate the largest insurer in one of the largest states as to medication indications - they have refused to give numerous patients the medication yet have no liability for their lack of knowledge and refusal to provide care .... Doctor you take all responsibility but we will make all the decisions ....
In Japan, the age adjusted prostate cancer mortality rate is significantly lower (2 per 100,000) than in the U.S. (14 per 100,000). However, the incidence of occult or latent prostatic cancer is similar in both countries
If EPA prevent prostate cancer the incidence of occult or latent prostate cancer should be lower in Japan
Like I said - Joe is going to pump so this time we all should dump ...
So you take it tid instead of bid - bit of a hassle but insurance companies dont mind hassling anyone if they can make more money - so my take is they will say - yea that could be so just take it tid ... problem solved ...
JOes giving a final pump - so we can dump .....
HK ..playing devils advocate - so just take a higher dose to achieve the necessary plasma level -
Pharmaceutical Manufacturer Rebates ---- if a physician received this the STARK amendment would call it a a "kick back" - yet its totally legal for insurers ....unbelievable
If you do it we can split the royalties !!
dukesking ...I agree - trying to remove myself from the echo chamber and remain objective - but I do sense a ground swell of interest in Omega 3's Its almost impossible for an unbiased person to ignore the data - that is in spite of NIssen etc - BP is picking up on it - still think someone will make combo soon ....and I have the name ..... VASTOR !!! ..... AMRN would pay a firm 500 k for that lol ....
Ten levels of organizations ...all getting paid ...with the goal to reduce pharmaceutical costs .... hilarious yet sad and true
NIce work HK - now we will see if its science or politics that runs the journal ...
Someone needs to do this study - could be huge - OK vascepa reduces inflammation - inflammation plays a role in numerous disease and aging - Problem for vascepa is how do you niche the med ? Very very difficult - so you simply do a study on mice one control group with vascepa the other without do you increase longevity ? IF you do boom .... sales soar ...
HA ha ... too many candidates .... Stock price is initially about human emotion which is then replaced eventually by logic .... the longer you have been on the board the more emotion I suspect you have and the higher your emotion pushes your hope for stock price .... the shorter you have been on board the less involved you are emotionally the lower is your projection ... of course with outliers in both camps - eventually as the dust settles and a companies ability to generate revenues becomes clear then logic takes over and a real value for the stock will appear ... BUffet operates on the latter - find a company that is making money and buy it
I would like to see a graph of length of time on this board compared to price projection
question in one of my CME quizzes !!
Management of Hypertriglyceridemia: Common Questions and Answers
Which one of the following has been shown to reduce the composite endpoint of cardiovascular death, myocardial infarction, and nonfatal stroke in patients with established cardiovascular disease and fasting triglyceride levels between 150 and 499 mg per dL? (check one)
A. Fibrates.
B. Niacin.
C. Icosapent (Vascepa).
D. Dietary omega-3 fatty acids.
EPS tells the whole story why stock price is in stagnation went fron estimate of 0.34 3 mos ago to 0.01
https://www.marketwatch.com/investing/stock/amrn/analystestimates
hmmm seem to remember someone mentioning this ....
...https://seekingalpha.com/article/4397669-matinas-learning-from-amarins-mistakes
Tell him to measure CRP not trigs
$9.75
When I saw their note that it was for 'cardiac health' I questioned whether there were any large studies of DPA for prevention of CAD - have not had time to research it - but that note tells me they are aiming for REDUCE IT indications and starting with trigs >500 - yes its a long time out - but if they went head to head with Vascepa and proved better reduction of CAD events - then AMRN would be destroyed - my concern is that the compound is DPA / EPA and it is possible that this combination is better at reducing CAD - we simply dont know nor do they even have a trial started.
However, - if it take 2-3 years for all the legal / infringement etc fallout to settle on AMRN then another 2 to get docs on board with EPA we could be five more years into this (just like statins) before the market builds - and just then a better product enters - all of AMRNS hard work and our money is lost
Its a new play - you take DPA and do a study - there is a chance it might work like EPA - if so you patent it you dont have a judge du and you take over the market - would be interested in pharmacy dudes take on DPA and its role in inflammation that will tell us probability of it working for reduction of cad - right now they are just looking at trig numbers but read what their website says
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As elevated triglycerides, especially very high levels, can lead to deadly cardiac events like heart attacks and strokes, LYPDISO is positioned to become a foundational tool for improving heart health.
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so its for high trigs ....but its also for heart health - they cant say that !!! THey need an outcomes study just like vascepa was required
I am not up to speed on this - it appears they say DPA / EPA - note that it is DPA not DHA will it receive patent protection - if so and if successful would destroy AMRN
https://www.biospace.com/article/releases/matinas-biopharma-announces-fda-conditional-acceptance-of-lypdiso-as-the-brand-name-for-mat9001/
Amarin call volume above normal and directionally bullish Bullish option flow detected in Amarin with 10,587 calls trading, 1.0x expected, and implied vol increasing almost 3 points to 82.41%. 1/8 weekly 5 calls and 1/8 weekly 6 calls are the most active options, with total volume in those strikes near 4,200 contracts. The Put/Call Ratio is 0.18. Earnings are expected on February 25th.
Read more at:
https://thefly.com/n.php?id=3220344
COuld it be that the brilliant minds that are thought leaders are finally understanding the difference between EPA and DHA ...tragically hilarious
Please have Dr. Bhatt present the science aspect !!!!
Amarin to Present at 39th Annual J.P. Morgan Healthcare Conference
January 4, 2021
DUBLIN, Ireland and BRIDGEWATER, N.J., Jan. 04, 2021 (GLOBE NEWSWIRE) -- Amarin Corporation plc (NASDAQ:AMRN) announced today that
John F. Thero, Amarin's president and chief executive officer, is scheduled to present at the 39th Annual J.P. Morgan Healthcare Conference on
Tuesday, January 12, 2021 from 2:00 - 2:40 p.m. Eastern Time.
There is an easy way to introduce Vascepa to docs
Heres my marketing for Vascepa ( needs work but I am seeing patients )
Vascepa ...its a statins best friend
Doc I am sure you are aware that statins have had a major influence on CAD and saved millions of lives. You might be interested to know that statins were discovered as a result of red yeast extract. WHen it was discovered that this natural substance lowered ldl researchers identified the substance responsible and that how statins evolved . Little else evolved for 20 years but now enter Vascepa - a natural substance, fish oil, was felt to have a benefit for CAD just like RED yeast extract. AMRN has identified and concentrated the moiety responsible for this remarkable effect just like statins were identified from red yeast extract .... and now you have the possibility of saving millions of more lives by using this amazing substance - if you have a patient on a statin - think vascepa to give them another 25 % protection from CAD. Think about it - you can prevent 1 out of 4 patients from having a life destroying coronary event by simply prescribing this pill; .... Vascepa ...its a statins best friend ....... then go on to explain EPA vs DHA
This approach removes the stigma of "fish oil" and help docs link the fact that statins which they use ever day were also identified from a natural substance - I cant emphasize enough there is no traction because docs think its "just fish oil" they all think it has to be complex to work - yet red yeast extract was not - make that link in their brains and BOOM the product sells
That idea would have cost amrn 200k from a marketing firm
Wow 7k for a new RX ..... AMRN owes me a fortune !!
FFS - I am so sorry to hear of your fathers passing on . Death leaves us in emptiness - my fathers passing took me two years to get over - cherish the people who remain and dont lose faith - there is indeed a reason and purpose and although we dotn see it we perceive it - May God's arms embrace you in this most difficult time
Pfizer (lipitor) did this to Allergan's crestor they beat it down with bad press - even thought crestor the better med they picked up on a miniscule d=side effect blew it all out of proportion in the press and it took years for the med to be seen for what it truly is
a few do ...most primary care and even cardiologists remain oblivious to the existence of the med
Yes now you are beginning to get the pic - this is why the 800 reps should be working on educating insurance companies as well as docs
RAf the best way for you to understand this is to complete all my prior auths for vascepa
... and therein lies the problem - they are not knowledgeable on omega 3 and they dont write the rx ...
If you want to understand docs and Vascepa look at it this way . As a family doc I am responsible for every product in a Walmart store . I know most of the products and what they are used for . I dont know any of the specifics - if you want to know the chemical composition of Dawn detergent and why that works on pen ink better that arm and hammer - sorry I dont know that information nor am I going to look it up - when you say thats your job to know that I laugh at you and say you have no idea --- you think that someone is going to memorize the intricate details of every product in the store - from grains of powder in ammo to bike metal mohs levels to the chemistry of various perfumes - I realize you have never lived in the real world and herein lies the purpose of marketing - you establish an easily understandable niche market for your product - when you go to the clerk and say hey where is that new detergent that actually strengthens fabric - and none of the others do that - they probably will know the product - they wont know why or how they wont know the chemistry - they wont understand the covalent bonds being broken up to realign the materials - and anyone expecting them to know that is in a worldly manner of speaking very isolated and sheltered
For trigs >5oo lovaza works better than Vascepa - if you are just measuring the trig number ( which is what most docs do )
FFS - I would be the first to admit that I dont understand bitcoin. It is hard for me to grasp the value of a random 64 digit hexadecimal number - discoverable by brute computing - I could perhaps understand an equation that has scientific value - but just a random number as having vale ? At least gold can be used in industry art etc - yet I guess it just all boils down to what someone "values" - if we can get everyone wanting something then the actual value does not matter - hence someone once sold pet rocks to prove that point
Third slide needs clarification they both show EPA and DHA being inserted at the sn2 position but yet they have different effects - clearly ITS NOT WHERE THEY are Being Inserted that cause the different results so why show the insertion ?
Send to Nissen so he can understand basic biochem ...
The best study that should be performed ...will EPA prolong life ....will take 2o years but hey that's a winner ....
They paid a 45% premium for Alexion - that would be about $7 per share for AMRN - I was in at $4.xx I will take it but I know others will be devastated with an offer like that