Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
I do NOT see the need to partner for Covid. But under the scenario you propose, one of my questions would be, “Who makes the decision as to how to allocate revenue for a combo therapy?” I could see a situation where Gilead would try to give Remdesivir the lion’s share of the revenue since they would then not have to give as large of a revenue split to IPIX. If we were going to partner, I think I would prefer we do it with someone who does not have a “competing” product.
Attila said, [
It’s amazing. We are so close to a game changing announcement on Brilacidin. But then, Wow! Just look at the number of fear mongering posts that are basically a dressed up version of “The sky is falling! The sky is falling!” LOL! It’s obvious that “Chicken Little” is alive and well on this iHub board. Bless their little hearts...
I can’t wait to see the 10K next week!
There was something awhile back about Leo’s plan to maximize shareholder value, but there was nothing said about selling the company. A specific company that has been successful at developing and licensing drugs was mentioned as an example. I don’t recall the name of that company.
Gohel said,
LOL!
Petemantx said,
I think you may have missed some of my posts because I have certainly addressed this point.
Petemantx said,
$4? LOL! No way. I might take my cost basis off the table at $5 but that’s less than 10% of my holdings. It may take a couple of years more, but I plan to stick around to participate as the company further monetizes our assets.
Lemoncat said,
Actually, as I recall, Polymedix was also investing heavily in another molecule that failed. If I’m remembering correctly, that other molecule and borrowed money were the primary causes of the Polymedix bankruptcy.
Petemantx said,
YES! LOL! Lock em up!
Lemoncat said,
It would have been nice if this had been PR’d this morning.
Dr. Bones said,
Could one of you longs who has the ability to search IPIX posts, please reply to one of BioHedge’s old posts or PM me the number for one of his old posts? I can use that to find the rest of his posts. Thanks.
This not a workable licensing arrangement. Why would a BP agree to it when IPIX can then license Brilacidin via IV to a competitor to cover the flu or ABSSSI or Ebola? Then doctors can prescribe the competitors version off label to treat Covid as well.
After the Covid crisis has passed, I could see Leo signing with a BP to develop Brilacidin for innumerable diseases (bacterial, virus, parasitic, IBD, and perhaps even fungal or other conditions). But hopefully Leo is smart enough to negotiate a sliding scale of royalties that gets us to 50% after the gross reaches a billion or two.
136 said,
20%? Absolutely not! If Brilacidin works against Covid, the governments of the world are going to write very large checks THIS YEAR. A big upfront payment is not worth much when the gross is going to dwarf the upfront payment in the short term. And giving 80% of the revenue to a “partner” who did NOTHING to get us to this point is an insult. Again, if Brilacidin works, we do NOT need a BP “partner”. We already contract the production and the finished product can be direct shipped to the appropriate address. All that remains is to deposit the checks (or just confirm that the proper funding was wired into our account).
HereToday said,
Banks do lend money to companies based on the company having a lucrative government contract. Another factor to consider is that companies often require a substantial upfront deposit when an order is placed. Since Brilacidin is purported to be inexpensive to manufacture, I would expect that such an upfront deposit would more than cover the cost of production.
Petemantx said,
It’s just newby’s foolishly setting stop losses on an OTC stock. The Market Makers are just enriching themselves by havesting some newby shares. The price will likely recover this afternoon.
If you set a stop loss order on this stock, expect the Market Makers to drop the price low enough to take you out. That’s just the way it is...
Thanks JFM...
Wrong? I don’t think so. Timing stocks is notoriously difficult. My perspective... If you get a chance at a “once in a lifetime game changer” the timing is not as important as the decision to invest and the commitment to stick with it. That was the case with Microsoft and I think that will be the case with IPIX.
Tyrus603 said,
I agree. I think that Brilacidin has the potential to pretty much halt viral replication and therefore stop the virus in its tracks. However, I also believe how much damage has already been done when they get Brilacidin will determine how long it takes for them to recover. Once the virus does it’s damage, the body will have to repair that damage. I expect that Brilacidin’s immunomodulatory properties will help with that but it could take some time for those repairs.
In other words the earlier you get the Brilacidin the better. This would be good for us because it means there will be more people being treated.
CallMeCrazy said,
Try this one. It’s my favorite.
It sounds like someone made a deliberate effort to sabotage a potential source of significant support by distributing spurious and fallacious but purportedly positive information on Brilacidin.
DrBones said,
So yet again, “The sky is falling! The sky is falling!”
Chicken Little said,
I like what you did there. I would add that from the heights that IPIX is about to obtain, the SUN will be easy to SPOT.
PJ007 said,
Do NOT use trailing stops for OTC stocks. The Market Makers can see your trailing stop (as well as any others) and will manipulate the price down (using those trailing stops to help drive the price down) to pick up your shares at a discount. Unfortunately for you the stock will quickly recover and you will be stuck buying back in at a higher price than your original trailing stop. We have seen it happen time and time again with IPIX.
Marking said,
Also, if we get the EUA for the IV treatment of Covid, I could see where when someone had surgery, the SOC would include hanging a bag of Brilacidin to protect the patient against Covid and whatever...
Farrell90 said,
Actually, I would think that if this Covid 19 trial is successful, then an Emergency Use Authorization (EUA) might be appropriate for our Oral Mucocitis application. Covid is a threat to anyone with a compromised immune system and cancer patients on chemo and/or radiation treatments certainly fit that bill. People are dying due to delayed cancer treatments due to Covid. After we get an EUA for OM, then it would be a very short stretch to an EUA for the dentistry application.
Man this thing could really blow up quick...
Farell90 said,
Or, we can all run around the barnyard screaming... “The sky is falling! The sky is falling!” But I guess that would be a “scream along” as opposed to a “sing along”. LOL!
ToInfinityAndBeyond said,
Exactly!
FatAlbert said,
Lava Soap, for when you have that hard to clean nastiness on the outside. And Brilacidin, for when you have that hard to cure nastiness on the inside.
When you absolutely, positively, and desperately need relief; try Brilacidin, the Swiss Army Knife of Drugs...
I was thinking the same thing but I would add... [
Correction:
At this point, I don’t want a partner until after the governments of the world are thru stocking up on Brilacidin. Why share the gravy? Oh, and by the way, that “buyout” is not going to happen without Leo’s consent. And he’s not going to give it unless the price is right.
Rdunnit said,
I disagree. The BP contact mentioned by Panoz1 was correct when he said that BP does not like buying one indication. They’d rather have the whole drug. That’s why Leo took the AlfaSigma deal at such a low price. He wanted to put a win on the board that didn’t compromise Brilacidin’s overall value.
Treatment via enema can used for a very limited number of indications and is easily separable from IV or oral administration. It is also the most risky deal (and therefore worth less) for a BP to make because it is possible that enema administration can be replaced at some point by a time released oral version. It was therefore the proper choice for a deal. It put IPIX in line for some revenue in the short to mid-term timeframes and left the high-dollar indications to mature. So yes, I think Leo has turned his nose up at more than one BP who wanted to get Brilacidin on the cheap.
Grumpy said,
Exactly!
Panoz1 said,
Well done!
My first purchase was in either 2011 or 2012. I have never sold a share.
I consider myself a “real” long and I have NEVER sold even one share of IPIX. And I don’t plan to sell any until after we uplist to NASDAQ. In fact, I bought more last week and if the price backs down again, I’ll buy even more.
I am very optimistic about this Covid trial and therefore believe that IPIX may well save the world! And I want to be known as one of the determined investors who saved this company by sticking with it for years in the face of blatant criminal manipulation. Assuming the Covid trial is successful, what should the penalty be for those whose manipulations stopped the Phase 3 for ABSSSI? Because if Brilacidin were already on the market, it would have been prescribed off-label early on in this pandemic and potentially MILLIONS of lives could have been saved. So what should be the penalty for actions that result in the negligent homicide of MILLIONS of people?
You are correct about the Brilacidin for the current trial. But perhaps Leo has special knowledge and therefore reason to anticipate the urgent need for an additional LARGE amount of Brilacidin...
Old grumpy said,
Better wording perhaps? “Tell that to that GME shareholders who know that at least 140% of the outstanding shares were shorted and that doesn’t count the untold number of naked shorts...”
TradingPro said,
This should read; “and naked short selling by any person or entity should: 1) Be punished by ALL involved having to regurgitate ALL gains from the trading of that stock and , 2) Fines should be imposed equaling at least the amount of those gains and, 3) All involved, including those who knew or should have known, are permanently banned from having ANY job or position with any company that trades securities, and 4) Those involved should receive significant prison sentences.”
Farrell said,
Well said... I would make the following change. “Phase 2 of a multi-national trial starts next week and all laboratory tests AND MULTIPLE PREVIOUS PHASE 2 HUMAN TRIALS FOR OTHER INDICATIONS show that it is HIGHLY LIKELY Brilacidin will show great efficacy in human patients.”
Newby’s might also want to know Brilacidin’s MOA. The Brilacidin particles basically stab the virus to death. This is the same way it defeated the bacteria which causes ABSSSI (Acute Bacterial Skin and Skin Structure Infections) in two separate Phase 2 human trials.
FatAlbert said,
That’s too close. I’m not sure that juice is worth the squeeze. Be careful...
Dr.Paddleboarder said,