Maybe look at it this way...Lincoln is comfortable betting 50M that avxl's pps will go up and in the bleakest of forecast...in the short term.

The better question is: how were they convinced of this?

Uplist. 50M. News on the 7th. Only points to one thing for me: phase 3 trials. and yes you are right, Lincoln won't be around for that.

Uplist will occur on Friday the 23rd. Imo

Either is stock manipulation.

Shorts, this battered wife is packing her bags and moving in with NAS. You will soon wake up-all alone- in your trailer wondering what happened.

If you want my attention, short a couple hundred thousand shares. Otherwise, it's all game, no skin.

i wont pretend to understand this. what i am assuming is that enzymes in a un-healthy brain MAY not be up for the task.

Chatted with a physician on this. Her question was "after the plaque is broken-up (assuming it is not on a molecular level like it formed), by what mechanism would it be excreted?" i.e. you're asking a un-healthy brain to assume the role of a healthy brain. In any case, having "debris" floating in the brain has the potential to turn a non-acute disease (AD) treatment into and acute situation...and good luck with the FDA on that.

My read: jittery traders giving up shares to private accounts of institutional managers. This will be a trend through November.

My advice: Zoom out. Look at a basic 6 months chart. Higher highs and higher lows...that's all that matters.

its back up. eom

AVXLD just became "invalid symbol" on TDA...interesting.

Some peace of mind:

Remember the the IP for this drug was purchased from Dr. Vamvakides. Later he would "challenge" the sale/ownership issue. This initially made some of us unsettled but after the dust settled...it occurred to me that there is only one legit reason why Vamvakides would do this...REGRET.

Shorts, please take a lesson from this man.

It's a German translation.

We may have a unicorn locked up in our barn.

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures: http://www.alzres.com/content/6/4/37

"During the 2002 to 2012 observation period, 413 AD trials were performed: 124 Phase 1 trials, 206 Phase 2 trials, and 83 Phase 3 trials. Seventy-eight percent were sponsored by pharmaceutical companies. The United States of America (U.S.) remains the single world region with the greatest number of trials; cumulatively, more non-U.S. than U.S. trials are performed. The largest number of registered trials addressed symptomatic agents aimed at improving cognition (36.6%), followed by trials of disease-modifying small molecules (35.1%) and trials of disease-modifying immunotherapies (18%)."

A great read.

Failure Upon Failure For Alzheimer's Drugs:
https://www.insidescience.org/content/failure-upon-failure-alzheimers-drugs/2731

Another Bullish write-up by the same author.

"This is a disease that is the 6th leading cause of death in the United States. Over 5 million cases have been reported. It is believed that as many as 13.5 million people in the U.S. could have it by 2050. All the major Pharmaceutical Companies have tried to develop a cure. Here is a horrific statistic about them; 99% of clinical trials regarding Alzheimer’s drugs have failed. That’s a gigantic number. It is hard to be optimistic but it only takes one time to hit the jackpot."

http://www.insiderfinancial.com/anavex-life-sciences-otcqx-avxl-pops-on-impressive-phase-ii-news/113965/

Personally, I think the deal has already been made. It is informal and not on paper. Misslings has chronies that are watching his progress. I suspect Nov. 7th has a formality aspect...with a partnership following shortly thereafter.

Why wait? Because Anavex is still an unknown to shareholders. The potential (publicly held) partner needs P2B data & NAS listing before investing.

The post Nov. 7th PPS (i.e. 12-18$) will give Missling plenty of options on how this deal is to be structured.

As I have said before, this is not an erectile dysfunction drug...this in not just AD...this is CNS.

IF 2-73 does what that preliminary data suggests...the Pharm that owns this IP will dominate the market until the sunset of the baby boomers and IP. There are Billions of reason to snatch this up sooner rather than later.

Exciting times! GLTA

This is an expected & reasonable pps uptrend.

At first look, Anavex is the shining star of today's investment conference. EOM

I also think folks did their DD over the weekend. It think this will be a common trend as we move forward. As you look at comparable companies (e.g. AX*N) you realize that George's $16 prediction is conservative.

I'm confident we will be in the low 20s post Nov 7th.

higher highs. Higher lows. EOM

Buckle Up.

Which in turn will be used to fund 3-71.

Wrong. You will understand when Pfizer hands Missling a check for 2-73.

I am now totally fascinated with this dude.

Thanks for the correction.

Nope. That should be a smooth transition

NYC,

I've got some issues with your post. Foremost, of course this is a gamble. There is no denying that and it goes without say.

As a statistician and as an "inside guy" in Biopharm, you should know that a greater N in AD is not likely to show you a significant "variation of age groups." (Early-onset is <5%)

Also please remember 2-73 has shown in a small data set to shatter the current standard of care by 400% (i.e. not 15%).

PDT another excellent point and one that I had not considered.

I agree, 100%.

I picked up a few thousand shares on TDAmeritrade today. It has been off and on today.

I feel strongly that the news was leaked. As still an unknown to most investors, it manifested into hack job article to designed to get web traffic to their site.

Things are about to pick up here. Expecting $8.12-8.18 close.

FYI:
After a patent application is allowed, it is sent to the Office of Patent Publication Allowed Files Area. From there it is forwarded to the Initial Data Capture, where the patent file is electronically captured. The patent file then reaches the File Maintenance Facility (FMF), and after all requirements have been met for issuance as a patent, the patent application is forwarded to the FDC stage. The FDC makes necessary updates to the e-file and puts the allowed patent application in an issue. On an average, an allowed application remains in the FDC process for five weeks.

In addition, the biggest evidence that we are golden is the uplist itself.

Missling has been great at putting the writing on the wall. The all-in bus has arrived.

Congrats. Sincerely. May I ask what your total net % increase was?

PDT I'm sorry that you are stuck in wicked web...more weaving is not the answer.

Sell fast. Lick your wounds.

Truly wish you and others would take 15minutes to see how exceptional this company is.

Yez

Great post. R/Ss have earned a bad name in OTCs. This is the kind you want to see! Look at a simple six month chart it is a logical and welcomed next step up for the trajectory of our pps.