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This is a blatantly false statement...
I get your point, but where did they establish that a mean score comparison is how they make their determination of meeting endpoints?
It's all part of the collusive game... spin all positive news into a negative narrative to provide cover for the collusively orchestrated price manipulation.
Interesting comparison. Hadn't looked at it that way.
It certainly indicates a bottoming, compared with the XBI, and at the 200MA (support?).
George, the trial numbers say 20% down titrated; not 40%.
George is wrong... it's not even close to 40% down titrated; it's 20% at most for each treated arm.
* 287 (86%) were titrated up to their targets... 30mg & 50mg
* 263 (79%) were not down titrated.
So, only 21 % were down titrated.
...where most (but not all) of the 21% were likely down titrated from 50mg to 30mg.
If any were down titrated from 30mg to lower, were likely offset by those down titrated from 50mg to 30mg. Therefore, it's reasonable to believe that the 30mg arm had the target number or more.
That would be approx. 30% of the total treated WT genetic patients (50mg + 30mg)
In your own mind...
It'll be interesting to see just how many patients fall into group 1 (Super Responders) in the P2b/3 AD trial. It could very well be 20-40% of the WT genetic patients at 50mg and even some at 30mg.
These are the patients who functionally IMPROVED during the trial... making blarcamesine truly disease-modifying!
That's an amazing bird... impressive imitations of other types of birds... even a chainsaw. LOL
I think you're right, there is a blarcamesine analog in there... i.e. a single drug providing therapy for a host of CNS disorders, even hypertension and insomnia.
Blackbird (blarcamesine) sing...
I do...
The FUDsters are all in collaboration and likely work for one of several collusive HFs which utilize illicit trading tactics to manipulate stock prices (spoofing and naked shorting w/FTDs). It's why 7 HFs are being sued for such criminal activity.
You've confirmed yourself to be a simple-minded MB blowhard who "denies" the existence of manipulation. Are you that clueless... or just someone who denies the facts because of his alliance?
Jesse has spent 6+ years digging into the science, more than most anyone on this board... and magnitudes more than you. And definitely smarter than a certain poli-sci major, who claims to be a biotech analyst/journalist... who you seem to look up to and support. Hmmm.
I've known Jesse for several years and trust his work. As an investor, he is doing serious DD to validate his investment, as well as try to find anything of concern... and after all these years, it seems he hasn't found any.
But, here you are knocking his work. Why? Is it because it supports a positive narrative that goes against the FUD narrative? I think maybe so.
You've repeatedly stated that you're "invested" in AVXL only because of the science. Yet, here you are bashing someone who has done extensive research in validating the science.
Something smells very fishy here.
LOL. Can you tell all your FUD coworkers to put me on ignore, too?
That's just silly. 10 years is the average time for a biotech drug to make it through trials and to approval and commercialization. Seems blarcamesine is right on target... next year.
We getcha... pay no attention to anyone who has anything positive to say about Anavex.
And when the company does release positive news, spin it into a negative narrative.
That's been your FUD MO from day one. You're an easy read.
Is this your first biotech rodeo?
You reveal your ignorance with each and every post.
Yep, and yet there are some here who continue to deny it. Deny, deny, deny... any association to it.
These FUDsters all work together...
XBI slowly inching upward, but AVXL is being held to the declining 200MA (5min).
No, there's no manipulation...
The Biogen purchase news jumped its declining price a whole dollar! (< 1/2%)
If not being held up by a journal's data embargo...
Agree... their focus is on Rett and AD filings.
However, it's reasonable to believe Missling has had business inquiries along the way... likely pending results.
Likely in discussions/negotiations, but might not see it announced for some time... closer to approval, perhaps.
The meaningful partnerships are likely in preliminary discussions... and won't be finalized until closer to approval, when the SP is significantly higher.
A very nice recap and reminder, sokol. Thanks!
That one I have on ignore. He's pathetic.
If he's back, then something is afoot with more organized scare tactics.
Anavex is not for sale...
You haven't been around long enough to see the workings of organized stock manipulation. It's much more than you realize... and pervasive in the market.
LOL. Your FUD is showing again...
Highly doubtful...
Yes, they have until drug approval to keep attacking, if that's their plan.
However, any BP partnership news would certainly mess up their plans.
If the Rett Excellence results are as positive as expected, then there'll be competition for shares.
They have 16 million to go...
Hitting the bottle early today, Leo? Your inner obnoxious bully is showing... which is most of the time.
If the cabal have it in their plans to take it that low before Rett TLR, I'll be ready to buy as much as I can.
They most certainly will need millions of shares when they accelerate their collusive short covering...