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And its only Monday !
And if Darren Daulton was in our trial was he on vaccine A or Vaccine B?
Four Years ago? We may never know !
We are melting away again. What else is new ?
Time to go into the Cave and wait it out Again .
Wow this day has turned around, Nice Blocks now coming in on the Ask.
Blocks compared to really nothing earlier.
Like everyone here hasn't noticed it!
Just makes me feel good writing about it !
Not just blocks but a small price movement also , doesn't take much to get me excited!
Lets see where this goes !
There are a number of events that can happen to move this stock up to 2,4 and even 6 dollars without FDA approval for DCVAX l.
Just the fact that they have DCVAX L Data and working the application to be submitted for one.
Sarcoma trial
Anything to do with DCVAX D
We are already getting additional press. We are appearing in articles now. Here is one from Chris's site, I think its been posted already
https://www.statnews.com/2017/07/21/mccain-glioblastoma-treatments/
Working relationship with big Pharama.
All this is possible and more.
All depends on the Data !!!!!!!!!!!!!!!!!!!!
A panel review takes usually 3 months after announced !! If we go that direction......
At 5 dollars I'm looking at 7 figures , If the data is good I expect to be there before any approval. Will I sell? hahahahha
Maybe a little to pay all the bills and keep the Wife happy !
Happy Wife yes Happy Life
You put it better than me.
I read almost everything, watch everything, buy all I can.
When we get approval for our sub type, I will have a life time of earnings in my account.
I still think that I have more orders executed than anyone here. amazing how it all adds up.
Keeping an eye on that long term tax date ! Every week we move I have more long time profits vs short term.
How Awesome it will be to finally get some data out from the company. So this board can get back to discussing the Business and also the next product!
Just a thought ! Have a Great Evening !
Thanks again to everyone here!
I know that I said this before but I can't believe how many shares I have and would have a half of the amount if not for this message board.
I think you press the buy button on the wrong stock within your portfolio.
This is NWBO - just a reminder LOL
Well this has been a quick month. July always is .......
Another month ready to bite the dust ,, Let's see where we go from here..
Can't believe I picked up a few more yesterday,,,,,,,
The few thousand shares is less than 1%, I won't feel any difference if this company moves up big, I just can't stop taking the opportunity.
When this stock goes over .50 it going to feel expensive LOL
FDA Commissioner on CNBC this morning!
Coming up on Squawk Box
Lets clear something up, The senator does not need some trial or special circumstance to occur in order to get a treatment. What the Senator would like to treat his tumor he will get.
So that our trial is complete is not an issue.
Or another trial to be fair
biobrooklyn
Thanks for passing that on to the board!
Hopefully DCVAX can help Sen McCain !
If they didn't store his tumor correctly maybe he would be a candidate for DCVAD-D. If necessary !
Contacts? Everyone! Chris work your twitter magic
A while back Linda mentioned that they were working with the best company to develop a completely sealed (Out of the lab) environment for developing the Vaccine.
My guess is that this was over two years ago. It was in one of her presentations. She also mentioned how this will bring down the cost of manufacturing. Maybe this was for DCVAX -D.
Main point the cost of producing the Vaccine is going to drop somewhere down the line.
I also remember how she talked about the time period for getting FDA clearance. Once working the process needs a year for FDA approval, they need to create a couple of batches and prove the shelf life with the drug.
Hang On - 1.92 mil shares in a hour.
She is getting ready to run !
Waited a few years for this moment/next few months.
Still can't believe how many shares I accumulated.
To back those dam cook county property taxes are coming due.
Big Blocks are still at Lunch but that's ok Lets move forward !
Wonder how much shares are out there for trading, not the float but the actual shares.
Take my shares out of that number
Finally - but not much here
News coverage about Northwest Biotherapeutics (NASDAQ:NWBO) has trended positive recently, Accern reports. The research firm identifies negative and positive press coverage by analyzing more than twenty million blog and news sources. Accern ranks coverage of public companies on a scale of negative one to positive one, with scores closest to one being the most favorable. Northwest Biotherapeutics earned a coverage optimism score of 0.43 on Accern’s scale. Accern also gave press coverage about the biotechnology company an impact score of 75 out of 100, meaning that recent press coverage is likely to have an impact on the stock’s share price in the next few days.
Northwest Biotherapeutics (NWBO) opened at 0.255 on Friday. The company has a 50-day moving average of $0.17 and a 200 day moving average of $0.30. The stock’s market capitalization is $48.91 million. Northwest Biotherapeutics has a 12 month low of $0.14 and a 12 month high of $0.98.
I have news on my google alerts but can't open it
It came across 30 mins ago
Google
DCVAX
Daily update · July 14, 2017
NEWS
Northwest Biotherapeutics (NWBO) Receives News Impact Rating of 0.43
The Momentous News
One of the product lines (DCVax-L) is designed to cover all solid tumor cancers in which the tumors can be surgically removed. Another product line ..
Wow look at the string of trades starting with the 250k at .27
Another 185k and many smaller these just came out at 10:18
22k 33k and smaller all within 2 minutes
And still we have .27 at ASK
Pattern is about the same as yesterday, maybe we get a small bump for the weekend today
Phase IV clinical trials: What else do we need to know?
Drugs approved by the FDA are often watched over a long period of time in phase IV studies. Even after testing a new medicine on thousands of people, the full effects of the treatment may not be known. Some questions may still need to be answered. For example, a drug may get FDA approval because it was shown to reduce the risk of cancer coming back after treatment. But does this mean that those who get it are more likely to live longer? Are there rare side effects that haven’t been seen yet, or side effects that only show up after a person has taken the drug for a long time? These types of questions may take many more years to answer, and are often addressed in phase IV clinical trials.
Key points of phase IV clinical trials:
Phase IV studies look at drugs that have already been approved by the FDA. The drugs are available for doctors to prescribe for patients, but phase IV studies might still be needed to answer important questions.
These studies may involve thousands of people.
This is typically the safest type of clinical trial because the treatment has already been studied a lot and might have already been used in many people. Phase IV studies look at safety over time.
These studies may also look at other aspects of the treatment, such as quality of life or cost effectiveness.
You can get the drugs used in a phase IV trial without enrolling in a study. And the care you would get in a phase IV study is very much like the care you could expect if you were to get the treatment outside of a clinical trial. But in phase IV studies you’re helping researchers learn more about the treatment and doing a service to future patients.
All the shares sitting on the Bid right now are mine.
Partially filled. .194
Maybe I can get them during lunch, they always drop during lunch LOL
And if not let'er go!
I just picked up a few more
Filled - Who needs lunch
Can't remember if Newirth received DCVAX? Anyone?
I know its from earlier this year ......
Can't find it within the article.
A Maui lawyer with brain cancer was given 17 months to live. That was 5 years ago
Wednesday, May 31st 2017, 11:37 pm CDT
Thursday, June 1st 2017, 3:03 am CDT
By Chelsea Davis, ReporterCONNECT
http://www.hawaiinewsnow.com/story/35562012/a-maui-lawyer-with-brain-cancer-was-given-17-months-to-live-that-was-5-years-ago
Lets get a percentage on the move.
So we know who wins that baloney Sandwich
Sucked Out? -- Heck payday is this weekend I hope they keep on sucking
This is borderline oh well
NO on the 600k trade
Looks like the largest trade was around 280k if you put all the multiple trades together for one order.
Around 6 50k trades today so far and it looks like 2 over 100k
Just multiple trades early on
857k buys to 128k sells
Does the board think that this will definitely go to a panel review?
Hope not, it will take 3 months for the panel review to take place(once announced) and another 3 months for their decision!
I've been on the wrong side of the panel decision in the past !
Not this time !
flip - This is what I was alluding to when I mentioned multiple vaccines a little while back.
Survival for 3-5 years - Take another sample create another vaccine and hopefully another 3-5 years.
All with DCVAX - L ---- how many vaccines would you call a cure or the next best thing. 65 year old person just started SS develops a tumor,
With 2,3 or 4 vaccines now that person is maybe 80 years old.
Enjoying family, grand-kids, holidays !
With no side effects traveling !
Not the best example but the message is there!
We are not even talking about improvements with the Vaccine down the road.
It was nice to see someone else post something similar.
This message board is the best !
After success here I would like to travel to next message board with the experts here! I read over 150 posts before I invested a dime on NWBO.
A few years ago ! I would enjoy doing the same with another company.
Please Don't leave me behind ! LOL
gus
Does anyone know why trades are showing up under the ? on the ADVFN website?
I just purchased some shares and Mine came up under that column.
Thanks
By the way the buys are overwhelming the sells today
821k vs 63k
When was the last time we voted for board members? Wasn't over a year ago
Maybe they can request a list who knows all I know is they have access to the list of shareholders
This is what I was told by a PR person, I assuming it was correct
From other stocks that I owned, The company gets a list of stock holders and their voting shares for company votes at shareholders meetings.
From the PR person !
Cherry
I could of written you last post here. Same situation just change the type of relatives and its spot on!
I know in past posts I stated that I was through buying, not true anymore.
Well into 6 figs
I'm so wrapped up here I sometimes thing that I lost my marbles.
Surely the Bottom for Northwest Biotherapeutics, Inc (OTCMKTS:NWBO)?
By Gene Daniel - June 12, 2017
http://oracledispatch.com/2017/06/12/surely-bottom-northwest-biotherapeutics-inc-otcmktsnwbo/
Seems an article just to get some subscribers
SHARE Facebook Twitter
Down, down and down some more has been the story for Northwest Biotherapeutics, Inc (OTCMKTS:NWBO) since the end of July 2015 where it reached $12.55, today you can pick up their stock for a measly $0.16 cents. But, are we now near a bottom?
This year started off fairly steady as NWBO was in rally mode until mid January, then pulled back before another brief uptick at the start of February. The price began a steady decline before gapping down on March 17th (due to an announcement that the Company will sell approximately 28.8 million shares of common stock at a purchase price of $0.26 per share, or pre-funded warrants in lieu of shares). Ouch.
From there on it has been nothing but South for the biotechnology company, dumping heavily at the end of April and reaching a low of 14 cents on April 25th. This was followed by a brief surge the following day, but this turned out to be fleeting as the market cap continued to get whittled away with another descent for most of May before finally making one last ascent, closing above the 50 day moving average on the 30 May but failing the backtest the following day and dashing the hopes of investors.
Here it sits at $0.16 cents and the question remains is the only way left up for NWBO?
Northwest Biotherapeutics, Inc (OTCMKTS:NWBO) is a biotechnology company focused on developing personalized immunotherapy products designed to treat cancers more effectively than current treatments and without the side effects of chemotherapy drugs in both the United States and Europe.The proprietary manufacturing technology they use enables them to produce its personalized vaccine in an efficient, cost-effective manner. The Company has a broad platform technology for DCVax dendritic cell-based vaccines.
Find out when $NWBO stock reaches critical levels. Subscribe to OracleDispatch.com Right Now by entering your Email in the box below.
The Company’s lead program is a 331-patient Phase III trial in newly diagnosed Glioblastoma multiforme (GBM). GBM is the most aggressive and lethal form of brain cancer, and is an “orphan disease.” The trial is underway at over 60 locations in the United States, Germany and the UK. The Company is also pursuing a Phase I/II trial with DCVax-L for late stage ovarian cancer together with the University of Pennsylvania. On February 6 a long awaited bit of good news was received as the partial clinical hold on the Trial was lifted by the FDA. They announced that the Trial has accumulated a sufficient number of events toward the progression-free survival (“PFS”) endpoint but not yet for the overall survival (“OS”) endpoint. Another product they offer is DCVAX-Direct which is currently in a 60-patient Phase I/II trial for direct injection into all types of inoperable solid tumor cancers. Trials are currently being conducted at both MD Anderson Cancer Center in Texas, as well as Orlando Health in Florida.
Investing in the biotechnology industry can be very challenging at times as it isn’t clear whether the drugs being offered will be successful in trials and also pass FDA regulations. Last year was a very bumpy ride for investors in this sector and they could be forgiven looking elsewhere but the outlook is promising for this year, especially for the immuno-oncology sub sector. Jeff Margolis, VP of RespireRx (OTCQB:RSPI) told Life Science Investing News. “I think investors should be looking at the immuno-oncology area, this is a sub-sector of the healthcare space that is coming into its own now and progress should be rapid “
The bottom line is, when a drug is seen as a failure by the market we see company valuations approach zero, and with the recent news that Northwest Biotherapeutics’ (OTCMKTS: NWBO) DCVax-L FDA hold being lifted there is reason to believe this drug could be highly effective. If this is indeed the case then the current valuation of 16 cents is heavily underpriced and offers a risk reward profile that most definitely favors the upside and very limited downside. For continuing coverage on shares of Northwest Biotherapeutics stock, as well as our other breakout stock picks, sign up for our free newsletter today and get our next hot stock pick!
Found this article with today's date on CAR-T cells.
I went looking at the many IHUB posts that I bookmarked over time.
Over-time? I could of said years, wow time goes by pretty fast.
And to see so many articles like the one below without any mention of DCVAX is a bit of a downer. Enough said, we wait!
http://www.sfgate.com/news/science/article/New-frontier-in-cancer-care-Turning-blood-into-11212500.php?hl=1&noRedirect=1
Pardres
Yes > 3 years but I would go through another process of DCVAX L after the 3+ years if the tumor came back.
If the tumor comes back take another sample and create another batch of DCVAX. Does that give me another 3+ years? Total of 6+ years
Interesting!
At what point do we call it a cure.
Repeat this process until DCVAX D is perfected and passed the FDA.
By that time another company may own the process.
You can substitute any number of years in my description.
So a 65-70 year old patient goes through 2 to 3 DCVAX procedures and that gives him/her another 6-9 years maybe more to enjoy their grandchildren / retirement.
Side NOte: DCVAX can bankrupt Social Security ! LOL
This can go on and on and on
Mav
If true that would be a terrific move, not only for our stock but for all stocks that are being shorted heavily. A few times and the hedge funds would slow down the shorting process.
But is it True? I will be listening in,
DAN - You should add Mav's post within your email to the company!
I have a silly question:
For the sake of argument lets say that DCVAX extends life to 4 years
when the tumor would come back and be detected by another scan.
Can the patient then under go another tumor resection and receive a new Vaccine of DCVAX? Given that the tumor had a new signature this would be picked up by the process where the new DCVAX vaccine would be adjusted and have a very good chance of attacking the new tumor? (For another 4 years)
I realize that this would never be attempted in a trial because the trail needs events. Which is a lousy way of stating the obvious.
Things have slowed down so I thought that I would throw this out..
And why are we Down ?
As of 12:06 est
2,899,541 buys
916,182 Sells
170,421 ?????
Go figure !
After careful review, I have flipped my thoughts on yesterdays presentation. If the shorts win a short term battle here. I'll win !
wink wink
With the paper coming out in the near future I believe the Dr. needed to hold back his presentation and just throw out a few hints as others have noted. He would not upstage the working document!
Also I'm going with the idea that I plan is in place. Long and Short for financing.
I don't post much but have been here for about a hand full of years.
I'm just anxious !
Thanks again for all the great information placed on this message board!
Iwasadiver - Makes sense, I was just looking for to much today.
One step at a time !
I feel good about the shares that I have right now, after buying more today I don't think that I will in the market for more NWBO. 6 figures is enough.
Would be nice if we could just move up and then sit and wait for awhile.
Let's say somewhere between 1 and 3.00
On No news
Summer will go by quickly!
Question for the board:
Do you think that DCVAX will have to go through a Panel review?
If so we are looking at a 6 month process. minimum.
Also, just didn't like some of the language used today.
ex: IF ONLY MICE HAD MONEY (something like that)
I felt like the Dr. was enjoying testing then testing then testing because its what butters his bread. I know a few people will not like that statement. I'm going to listen again and take better notes of the words used.
For my situation I'm very long and not selling, just disappointed...
This was the big show and nothing really happen. One extra slide added to the past presentatons. We all knew that everyone is living longer.
Because of the money situation, something new needs to come out soon!