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If we get...
1) PK/PD (and hopefully 2a update)
2) RTT trial start
3) PD trial start
4) AD 2/3 trial start
All between 11/1 and 12/31.... they'll have to start calling Missling RocketMan.
No. He said first the PK/PD will be released. Then the RTT trial will start. Then the PD trial will start. Finally the AD trial will start.
Missling said it... not me.
I truly believe the purchases had to be done as an intentional signal to stay long and not lose hope right at the big moment.
I doubt that there is any "numerology" at play in them though. I think the number is just arbitrary and has no other specific meaning in and of itself.
Nothing will happen till CTAD. That will be the big PK/PD reveal. That will be followed by RTT trial starting, followed by PD trial start, followed by AD trial start.
It has been stated by Missling himself. It has also been reiterated in print several times including in the slides yesterday (#3 & #22) that the first thing that will happen is PK/PD release. We now know that this is going to happen around 11/1/17. Only after that will RTT trial start... followed by PD.... followed finally by AD.
The time from 11/1/17 to EOY is going to be jam-packed with heavy duty catalysts! Maybe a buildup in the second half of October in anticipation??
Yahoo!!!
Slide 12 shows the trial protocols for RTT. Looks ready to go to me.
Slide 12 is nice to see. They already have the details of the RTT trial all set. ~90 patients.
Is it possible that we might even be moving forward as we speak with the surveys and 4-week observation period?
It says that "ANAVEXâ„¢ 2-73 is an orally available drug candidate that restores cellular homeostasis"
This is not ambiguous in any way. It definitely states that this drug candidate restores cellular homeostasis. I'm not changing the wording at all. It can't be misconstrued to mean anything else without swapping around the wording.
Dr M filed a form 4 just MINUTES before the presentation began. Hmm.
Everyone can believe what they would like to. But the quotes say what they say. It's not really debatable.
I disagree. They are not saying it is "a candidate to restore homeostasis" as if the restoring of homeostasis was in question.
What they are actually saying is that it is a "drug candidate that restores homeostasis". This statement is saying it does in fact restore homeostasis, but because it is not approved for use yet, we are calling it a drug candidate.
Here are the actual quotes from some PR's:
From the PR announcing the presentation today at the Ladenburg Thalmann 2017 Healthcare Conference:
"ANAVEXâ„¢ 2-73 is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors."
From the patent PR:
"ANAVEXâ„¢ 2-73 is an orally available, small-molecule activator of the sigma-1 receptor which, data suggest, is pivotal to restoring neural cell homeostasis and promoting neuroplasticity."
From the PR announcing Dr. Cole coming aboard:
"ANAVEX 2-73 is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors."
Anavex continues to assert that 2-73 "restores homeostasis". It has been stated more than once. I would say that they aren't withholding bad news. They are openly stating good news. They aren't giving any further details, but the statements they are making are undeniably positive.
Argue all you want about the reason for the lack of detail, but let's not try to say something good is bad.
AXON did show statistically significant results... and they were bad.
They said there was no "significant improvement", not that the results were not statistically significant.
You had to see this coming. They're pumping a dry well.
I wonder how many people have submitted applications for the aren't trial so far...
I think the purchases were leading up to the PR today. He bought Monday and Wednesday this week and then PR on Thursday.
That tells me that the conference is the "big one". Especially since the PR today was so generic and didn't really say anything new. I think we will get a big surprise Tuesday morning.
One huge detail about the PR... it still says "restores homeostasis". If they were in possession of negative news they could not legally or ethically use that kind of terminology. Just another breadcrumb.
Grab a front row seat for Tuesday!
Correct. Big week ahead!!
Thanks! Need all we can get!
I suspect PK/PD, 18-month update, and announcement of Rett by Tuesday morning at a minimum.
Somebody mortgaged their house...
Much easier to sell a bunch of $5 calls and then manipulate below $5 before expiration. Always easier to move it down than up.
Here's a wild idea I had... could it be plausible:
Perhaps the new regs would pertain to newly-released data only. If data is released before new regs they could not be considered in light of the new regs.
So maybe data today does not qualify for special consideration or treatment by FDA. But if they release the data after the new regs, maybe there would be a smoother road to approval.
I stand corrected. Lol!
The Short's fantasy world will come crashing down soon enough. Heading into good times for Longs in next few weeks.
Not the question. Try to follow the bouncing ball.
What else explains it? If you have another plausible idea, by all means share.
That doesn't mean it's not true. It simply means they are strongly cautioning you to not make investments based on a rumor which may or may not be true. Safest thing to do is assume it's not true.
Ihub does same sort of thing in their disclaimer:
"All messages, including iBox content, are the opinion of the posters, are no substitute for your own research, and should not be relied upon for stock trading or any other purpose.
Also, keep in mind that moderators may or may not have a position in said stock. Being a moderator isn’t a sign of endorsement."
Options expire tomorrow.
Nothing new has been posted on that site... wallstreetwhispers.
There is no logical reason for it except to send a message of confidence to investors.
Agreed... Until we get a definitive move in SOME direction it's way too open for wild speculation.
That being said, I am of the belief that it will turn out good in the end.
That "whisperer" sure did clam up all of a sudden...
Isn't there another conference/presentation coming up soon?
Like I said, I'm looking for his estimate of three trials starting before EOY 2017. That's the timeframe to watch.
No you don't. And I'll do my own thinking.
Again... thinking it will be 12 months till substantial news is ludicrous. You might as well suspect that the sky is going to fall.
It's absurd to even think it could be 12 months before substantial news. What a non-starter!!
If the meeting is confirmed as true, where does the pps go at that point? I mean if only the meeting is confirmed. No info about what was discussed.