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Let's go Northwest time to make a move before someone passes you up!
Especially with the new Rights program from FDA!!!
https://www.yahoo.com/lifestyle/m/637e2902-8cfa-3547-94c9-06896a9edd25/ss_new-cancer-drug-93-percent.html
March 30 (UPI) -- A new cancer drug called larotrectinib was effective in 93 percent of pediatric patients tested in a Phase 1 clincial trial, researchers announced.
Researchers at University of Texas' Southwestern's Simmons Cancer Center in Dallas tested larotrectinib, which targets a fused gene called TRK found in many types of cancer in a clinical trial. The findings were published Thursday in The Lancet.
Larotrectinib is the first cancer drug to receive Food and Drug Administration breakthrough therapy designation for patients with a specific fusion of two genes in the cancer cell regardless of the type of cancer.
"In some cancers, a part of the TRK gene has become attached to another gene, which is called a fusion," Dr. Ted Laetsch, an assistant Professor of Pediatrics at UT Southwestern and lead author of the study, said in a press release. "When this occurs, it leads to the TRK gene being turned on when it's not supposed to be and that causes the cells to grow uncontrollably. What's unique about the drug is it is very selective; it only blocks TRK receptors."
These TRK fusions occur in a few common adult cancers, but they appear frequently in rare pediatric cancers, including infantile fibrosarcoma, cellular congenital mesoblastic nephroma and papillary thyroid cancer.
Larotrectinib, being developed by Loxo Oncology Inc., is part of class of molecules known as kinase inhibitors, which cut back on the enzymatic activity of a key cellular reaction.
The Phase 1/2 trials began in December 2015 and are scheduled to be complete in December 2019 with 92 participants.
"Every patient with a TRK fusion-positive solid tumor treated on this study had their tumor shrink," Laetsch said. "The nearly universal response rate seen with larotrectinib is unprecedented."
The study was conducted at eight sites in the United States between Dec. 21, 2015, and April 13, 2017, among 24 participants ranging in age from 1 month to 21 years old. Seventeen had the TRK fusions and seven did not.
All but one of the patients with TRK achieved an "objective response," according to the researchers. The one exception had tumor regression that did not meet the criteria for objective response.
Flipper - How excited should we get when assuming we are at a 20 -25 percent effective rate with DCVAX-L??
Don't know if you would like to answer that but I thought what the heck I'll throw it out there anyways.
Stock Price? I really don't care it will be higher than where we are now!
More importantly, we will get some press and start moving to the big stage.
Go Ramblers !
Lots of baloney going on today.
It seems the bid and ask are adjusting to almost every trade.
They are bouncing the bid and ask.....
anders - I don't care if they put out another 100 million shares. If this product works I could buy a garage full of cars.
What ever they have to do Im all right with, but its time to bring it on!
Everyone to the West Wall, they are attacking!
Place all those new cars against the gate for additional support.
Don't worry will be able to replace them later.
The gate is coming down, .2999 We need more cars
Tilt - You have any extras?
Chris how about you any extra cars?
zillions ! LOL --
Short Week this week !
fyi - Next Week is a short Week !
So my guess is another week of nothing.
Hope I'm wrong, If not we are moving into April my Friends.
I think that I'm making the wait harder on myself because I'm watching almost every trade. Take Lunch off LOL
I'm done averaging down, actually sitting green but I'm not here for a little green. I setup my alarm clock on, if we approach June 1 with no news I will sell my first 100k shares during the days leading up to ASCO.
And if no news by then I will feel good about that sell......
Come on Linda --- Give us some breadcrumbs via news release.
I agree - its called being prepared !
BO - 20 to 35
Follow the DCVAX!!!
You might be reading a little to quick
This is what I posted as fact !!!!
I really like the breadcrumbs that Senti posted: No opinion – just the facts !
UCLA is moving its 18th Annual Brain Tumor Conference from March of this year (when it normally presents) to May 18th (8:00 a.m.) and 19th.
(Note: The ASCO embargo for regular abstracts is lifted on May 16, 2018 @ 5:00 p.m. PST)My optimistic interpretation. UCLA might have more to share with patients regarding DCVax-L 39 hours after the embargo lifts. Should know if this guess is hot air by April 25, 2018 when regular abstract titles are released.)
First of all let’s bring up the fact that Chris has signed a non-disclosure Agreement during the last sale of shares to the retail investors. He might be in a better place with management because of this agreement, no matter what he is told he cannot reveal.
So, Yes I believe that Chris and everyone that participated in the last offering that signed this agreement may know more than us on this message board. Just guessing, but this is my thoughts …
In addition I don’t think Scott Gottleib manages his tweeter account, he most likely has someone who handles all of social media for his department. Some tweets may be brought to his attention but overall he is too busy with his day.
And finally, if anyone was trying to dump a few shares by posting or tweeting, first of all its a waste of time because this is bigger than any tweets or message board. We also would be able to recognize the change in stock movement with the way the volume has been running lately.
I really like the breadcrumbs that Senti posted: No opinion – just the facts !
UCLA is moving its 18th Annual Brain Tumor Conference from March of this year (when it normally presents) to May 18th (8:00 a.m.) and 19th.
(Note: The ASCO embargo for regular abstracts is lifted on May 16, 2018 @ 5:00 p.m. PST)My optimistic interpretation. UCLA might have more to share with patients regarding DCVax-L 39 hours after the embargo lifts. Should know if this guess is hot air by April 25, 2018 when regular abstract titles are released.)
Follow the DCVAX - One more item - Be Prepared, Have a Plan, Most will sell to early! Its the retail curse
Ace - I don't have answers to your questions but all I know is that I would not what to be the Big Pharma that lost DCVAX to my competition.
I might end up dominating the solid cancer tumor industry with DCVAX.
OK - A little hype can't hurt anyone. We all have our solid positions by now.
I'm following the DCVAX to Big Pharma -- if we get a few shares along with a much higher price GREAT.
All depending on results of course.
Can't help myself -- If I'm the CEO/Board deciding to make an offer, I would like to make the first offer and close the deal before my competition gets their act together.
Price ??
Lets have a great week everyone. MACD LOOKS GREAT
Anyone see the cover story on This Sundays - Sunday Morning CBS ?
Les and Linda - If you read this blog take some time and watch this video, People need DCVAX Like this mother with two children....
End the Wait !
Every time I see stories like this I think of DCVAX. Even tho its not brain cancer I think DCVAX would be able to help her also.
Stage 4 Colon Cancer:
I cry during movies - Golden Pond - Private Ryan at the end at the Cemetery and watching this story. Borrowed Time
Borrowed time: Reflecting on a life with cancer
Its an amazing story
People need DCVAX now ---- -
https://www.cbsnews.com/news/borrowed-time-julie-yip-williams-reflecting-on-a-life-with-cancer/
Singer Lorna Luft, the daughter of Judy Garland and half-sister of Liza Minnelli (above right), has been diagnosed with brain cancer after she collapsed backstage at a concert in London, Associated Press reported.
The singer’s representative, Victoria Varela, told TheWrap’s via email that Luft, 65, collapsed backstage Friday night following the second of her four sold out shows at London’s iconic Pizza Express Jazz Club.
Luft’s husband, Colin Freeman, had been concerned that she was forgetting lyrics and a monologue during her performance. She was rushed to London’s Chelsea and Westminster Hospital, where she was given an initial diagnosis of a brain tumor and is undergoing additional tests, Varela said.
Price moved up and down but basically stayed in the same place last week.
BUT take a look at the MACD - I like to keep an eye out on the MACD.
It move to a barely positive position. NEXT WEEK Maybe, looks good for the price. I'm not saying news
The cool think about looking at chart indicators is that its easy to look back at history and see how the price moved the last time your indicator was in the same position.
Hey - I bought a few more last week even thought I stated that I was finished.(because of the MACD) I'm finished again !!!
Can't thank this message board enough for all the info during the last I think 4 years ) Time fly's
Everyone should think about following the DCVAX! If Big Pharma comes on board or any other way. Those with enough shares will not need another HOME RUN all you have to do is follow the DCVAX!
5.00 I'm set for life - Do I sell everything at 5.00 Heck NO!
Maybe even 4.00 Averaged down over the years - As I said in the past, I believe that I have more purchasing transactions then anyone here. I wish it was shares LOL
Lets finish this week and then rock !
flipper - That's a great post
As an Old Alter Boy I'm going have to read that post a couple of times!
And copy it just in case it goes away
Have a Great Pulaski Day Everyone !
Just picked up a few more -- against what I have been saying
I really like the way the MACD looks for the last 3-4 days
Compare it to the Dec 19th area on the chart - it was recovering back then also and then took off - and I'm talking price with the Took Off words
Happy Pulaski Day !
Hank
Its legal for any one in Congress !
Happy Pulaski Day !
Jim Kelly announces his oral cancer has returned!!
Could DCVAX be a possible treatment for this type of cancer?
Just Wondering about the possibilities
I notice any cancer story I come aware of, even in a store or at work if someone is talking about a situation with cancer.
I would like to say you need to be aware of DCVAX for a treatment but we are not there yet. Maybe soon -
Its a downer that I cannot introduce people to the treatment.
There was a time many many moons ago when the company released news out to the shareholders --- If my mind is still working correctly I remember that I noticed their favorite day to release news was on a Thursday.
March 1st might be one of those Thursday's ---
But I'm one of the pack that believe we will see a nice price rise before news, always seems to happen no matter which stock I point to.
So what the heck -- lets get that upward price movement today !
Still Positive !
June 1, 2018 ?
Beginning of ASCO 2018 ----- Just Wondering
jdheart - relax -- give it 30 minutes and you will be posting that you are in love with Linda !
Guaranteed!
Interesting trade just went by at .323295
Another trade at the same price LOL
come on really ?
Every time they fail our market Cap should go up!
Linda knows this ! Sly Fox that she is !
We just need you know what!
Apparently eTrade is still having problems with their phone app.
OK - My bid and ask from etrade is going to 0 and 0
I reset and it happen three times.
Anyone else ?
Its Alive !
Maybe just Maybe volume will reach 1 million today -- Looks good right now
I didn't check but if we hold and inch up a bit more the MACD will look like its turning.....
And all this during the lunch hour which is the second amateur hour of the day in my book
3 hours from now who knows but that's the way it looks now
Will there be a bidding war? YES
If we achieve the results that we all expect and we know a few people that were able to receive terrific results ---
How can a company not place a bid in for DCVAX?
Tell their board of directors and share holders that they were not interested with treating all operable tumors and all solid tumors down the road.
Have their drugs/treatments become obsolete. It can happen !
World Wide !
We are waiting for the article to come out? Wait and see how fast additional articles hit the internet - again if we receive results
This company is a disrupt-or --
I only believe what I write because of Alan Butler --- Kate -----
and a few others .....
Have a great day ---- Still the waiting is driving me nuts LOLOLOL
Flip - I have no idea, I just watched in on the news today.
Thats all I know, I was eating lunch at home because of all the snow in Chicago and ran for my control to DVR the segment .
Boy its snowing here like crazy , non stop
Fox 32 News at Noon --
Reported by Natalie Bomke (fox) - story on her facebook - viewed 50 million times
Kara Turner-Huber – trial patient – Stage 3 melanoma ,2 months to live in 2006 - still alive
Janet Hurt (facebook) – 30 tumors in lungs – 3 months to live --17 years later still here \
Dr Timothy Kercell (sp) - Describing news on report
Standford Univ - Injected two immune stimulating agents in mice – wiped out the cancer
Current underway at Rush and many cities
Are we losing time?
I don't know, I have been excited here as much as anyone.
I'm losing that excitement
Just a minute ago fox News just played a very good segment on that trial
with cancer the vaccine and the mice. I took it for granted that it was the one that has been in the news lately.
I quickly DVR'ed the segment. It even had the facebook of one of the people taking the treatment. It also mentioned the doctor's name and that it was taken place at Rush in Chicago.
I could replay if and get some additional info if anyone is interested.
Vaccine we have, its the Time that I'm worried about.
One patient had 30 tumors and now zero . I thought they were just working with Mice?
Your Thoughts
How long is the list waiting for DCVAX if he must go to the bottom of the list and that indicates sometime in August?
I might of missed something I just skimmed over the explanation while I'm watching CNBC talk about the drop today.
The first time I disagree with you Flip .
If Senator McCain requested DCVAX believe me he would be able to get all the vaccine that they could produce for him.
Trial or no Trial
Which poster here would like to face the Senator and tell him that he cannot have the treatment because the trial has stopped.
I'm not saying he did or didn't receive DCVAX just saying he received it if requested.
If he did receive DCVAX and results were good you can forget about any prediction about market caps. If disclosed the market emotions would run wild. We might not even trade for half of the day.
Its a long shot but even that 100 to 1 horse comes in once in a while.
With our luck the article should of came out today with the Dow Down 600
LOL -- Just saying and I'm a happy camper if we hit 3 to 4 dollars
I could retire happily
Dow - 1.2 billion to sell going into the close from Art K
I love with the toliet flushes -- Kevin O'Leary
Interesting twitter comment from AVA - Thanks Chris
I’ve contacted $NWBO since last April. At first I was told I may get #dcvax in UK. I’m willing to travel and pay all expense upfront if I can get the vaccine. I contacted $NWBO last week and they just ask me to wait till no certain date. #gbm patients don’t have much time to wait
My heart goes out to AVA, seems like she is at least 12 months into her battle with GBM. I hope things move in the correct direction for her SOON.
President Trump speaking now - Mentioned Right to Try again !
In addition - Lets all take a deep breath ---
yes manufacturing is important, Lets just get there
It would take at least a year for a new production line to get the OK from FDA. So I think they would utilize current production and expand their own production as they increase the possible cancer types for treatment.
Just my Opinion ---
I remember Linda stating it takes at least a year to get the OK from FDA for a new production Line.
And was proud that they were on their way.
Also something about waiting for months of shelve time to show that the vaccine is still able to preform its task .
I like that --- Its Task LOL
have a great day - Yea - I did something that I said I would not do anymore, purchased a few shares with my bread crumbs today -
For the sake of conversation the ask was .335, I placed my order there but they gave me .3325 and we moved up to .34 after that, now were down a bit.
Still think we end positive for the day
We'll see
Keep an eye on the MACD on this website.
Looks like we are turning the corner.... Moving toward positive Now
Same is true when moving down - then sell if you are a trader
(I'm Not, its just fun to watch)
Lets see if it continues today or falls back ...
You can almost predict price movement with the MACD.
All you have to do is view the history of any stock. ....
Not much left for anyone to say about company or DCVAX.
Just to wait for the fireworks !
I hope we don't have to wait for July 4th ......
Yes This happen to me also when I called them up and told them to cancel my margin acct. The next time I purchased shares it created an additional entry in my acct for my NWBO shares.
I was going to call them on this but haven't yet.
I also wonder how many shares I voted for last week. Did it include both entries? I didn't take the time to look it up !
I'm wondering if they moved my initial shares into a cash acct and the other shares in a margin acct.
Thank you so much for placing this link on the message board !
I needed this today !