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Not sure why you're posting info that's 2-yrs old?
Interesting article... thanks!
Agreed. With good/great news, this time will be different. The retrace from any breakout peak will be short lived, as there will be too much demand.
Dr. M was waiting for you to return. Now, should be anytime!
Not true... he said the results would be provided IF available by Q1. It has obviously taken longer than expected...and I wouldn't be surprised if they are having the data reviewed by more than one party, including the FDA.
Oh dear! The leak is getting bigger!
Well stated... I'm with you on this one!
Way to step up, FooBar! You'da Man!
...and a very small leak at that. :)
Josh, we're up 2.5% today on NO NEWS. Does this concern you?
I thought, and others have said, it was in September.
Data and Partnership...
Though it's rather easy for a company to keep a lid on data, until which time it decides to announce the findings, it's much more difficult to contain news about a partnership...too many people involved. Therefore, at some point, leaks will start to infiltrate the market, which will begin to affect the PPS.
It's just a matter of time.
Thanks... I just realized I was on the AAIC site. No mention of Anavex there yet.
Reviewing the Bio 2016 site, I could not find where Anavex is presenting or exhibiting. They are not listed on either list.
Does anyone have different or additional information about their participation?
Any chemists here who has access to a lab?
You can make your own 2-73... C19H23NO.HCl
If you have not done your DD, to answer the question for yourself, then I recommend that YOU not invest in this company.
I could be wrong, but believe the 14 mg minimum dosage came from calculations and computer modeling, not actual dosing.
Correct. Dr. M stated during the shareholders mtg that Sigma-1 acts as a cell chaperone throughout the body. They have seen laboratory results that indicate heart health may be improved.
If it walks like a duck and acts like a duck...
Time will tell... hope you're holding shares.
It amazes me how the world's next miracle drug still remains the best kept secrete!
No matter how much it's beaten the horse won't get any deader!
Here's a thought...
If the data is available, but is not anymore significant than the recent ODD PRs, wouldn't you think that it would have been released by now? The fact that it's taking this long tells me that the data is very significant, is being shared and that likely a bigger announcement is in the works.
Breakthrough Drug (or Designation)
I thought it a bit peculiar that P3 was not being scheduled earlier than first of next year. It would seem that Anavex, as well as the FDA, would want to move more rapidly if it's deemed P3 is necessary.
Perhaps it's because Anavex needs time to arrange the needed partnership for funding...or it is purposely delayed to allow the FDA time to analyze and determine if BTD is warranted, not having to spend any money in the preparation of P3? Certainly more questions than answers.
Soon, grasshopper, soon...
Have a great trip! AVXL might be $15 when you return. :)
Yes, and in that .1% are the nefarious cabal that's keeping a lid on the PPS. Once 10% or more of the investing public are made aware then the top blows off of this pressure cooker.
I find it absolutely amazing that we, on this board, share this knowledge of an impending breakthrough "curative" treatment that 99.9% of the world has no clue is coming.
The MF article (bull vs. bear) seems to be a CYA "bridge" piece that starts to move them from a totally (fabricated) bearish position to finally suggesting there could be value with AVXL. This way, when the great news comes out, they can fully move to a bullish position, without looking completely foolish.
dmb, you do realize that AF, JF, MD and the like are all part of and hired by the nefarious cabal that manipulate microcap stock prices? I'm sure they don't even believe what they write; they're just paid to write it so that the MMs and hedgies can point to something to "justify" their actions.
Unfortunately, it's necessary to take the time to call them out on their negative and slanderous posts, in order to make naïve investors aware of the game. Thank you for taking the time to do so and to report them to authorities.
For those who cannot understand why the PK/PD results are taking so long, here's a primer on the subject; it's quite extensive...
Introduction to Pharmacokinetics
and Pharmacodynamics
http://www.ashp.org/doclibrary/bookstore/p2418-chapter1.aspx
By the time there is significant off-label usage, we'll likely be 6 months into P3, which is when I believe the FDA will grant approval anyway.
Generally speaking, that's correct. But once the partnership is announced (provide a recognizable one) and with good 12-wk PK/PD data, news will begin spreading within the industry and on Wall Street. That should sufficiently get the news flowing quickly.
Many believe that manipulation is one sided (down), but the truth is it's both. The positive reactions to small PRs, such as today's, and the AU media spots are primarily the MMs and hedgies exaggerating the direction of the movement. Then when the upward move fades, they begin to bring it right back down. They thrive on volatility.
This stock will not see sustained lift until there is a partnership and widespread national news, which should happen in the coming months. For this company and its positive developments, patience is a virtue.
Their sole purpose is to disparage the company.
Seems to me they could present the MMSE, cognitive and daily-living results without the PK/PD, if that's all that's holding it up. PK/PD don't necessarily apply to efficacy.
ip_man, I'm totally in sync with your line of thinking.
Nice analogy... and often times the price of admission is less when you buy early. :)
Does the below not apply? Isn't it broad enough to encompass AD?
2-73: U.S. Pat. No. 9,180,106 granted on 10/21/2015
SIGMA RECEPTORS LIGANDS WITH ANTI-APOPTOTIC AND/OR PRO-APOPTOTIC PROPERTIES, OVER CELLULAR MECHANISMS, EXHIBITING PROTOTYPICAL CYTOPROTECTIVE AND ALSO ANTI-CANCER ACTIVITY.