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Well said. Thoughtful and thought provoking.
A Big Time outfit shorting their web hosting........hope the refuting of their allegations becomes a document of record.
Also think it wise to test CI combo outside the cranial cavity first as it should aid in dialing in the dosing to avoid or minimize the possibility of AE. An AE event in this trial would be less threatening than in a GBM trial.
doingmybest, I was commenting on financing not trial results. For reasons stated additionally comments from Adam (Nasdaq) and ic (lower burn rate-to put a nice spin on it) don't think we see PR today. Sorry for the confusion.
I'm not expecting a PR today. With the election making it a "big news" day it would provide some cover for a bad news PR. Conversely not a good day for a positive PR.
It's possible it is completed. I would assume if anything is PR'd today it would not be positive. I'm not looking for a PR today, but anything is possible.....
Congratulations. They're celebrating like it's 1908 in Chicago.
Sometimes good things take time........
Assumed the appropriate CI for the targeted protein expression. Several CI approved with more on the horizon.
Hypothetical: Since CI's are relatively off the shelf (easier and less risky to produce) therefore likely to be administered first could FDA be attempting to get the lay of biologic landscape for follow-on combination of autologous origin (Cart-T or Dendritic)?
Not that this would be acknowledged.
Interesting. Plausible for the halt IMO.
NW had his own investigator(s) looking into NWBO allegations. Perhaps he's not less interested just more comfortable with the stewardship. And yes their are two sides to this and every argument......perhaps three or four during this political season.
doingmybest, Agree and glad you've been able to share you personal experience with the board as I've been too busy of late to post much of value. Your posts have been spot on, albeit lost on some readers. Hopefully we will have some clarity soon on NWBO's trials. For a while several of us have had keen interest in what has/is transpired in Germany. I have another slightly different automation senerio somewhere in-between yours and Doc Logic's. But I'll not add it to the mix as it appears we will get some resolution soon.
(Still have a hypothetical I hope to share with you and others at an appropriate time and/or venue. More than most you and Longfellow95 will touch on aspects of it from time to time)
Trick or treat? Seems apropos.
There has been a lot of Cognate housekeeping of late. Latest financing could be to square things with Cognate investors, for their part in MFN termination, before moving forward with NWBO centric plans.
See post 36755 for perspective on BP level of investment to establish manufacturing on two continents.
I think we get affirmation today.
(However, in reference to your post from yesterday I'd rather see if CT can hit curveball........and my wife thinks my verbal communication skills are cryptic.)
Posted a week ago Monday see post 78635
Yes. But also another opportunity to point out to others the process may "optimize" the science. Big hint from from Fraunhofer here. Thanks
In general are the Germans adept in process automation?
Wasn't November Diver's and/or Doc logic's call? Must have slipped Les' mind on phone???
Germans buying via BoNY?
Document properties for the .pdf show 9/28/16. And changed on 10/10/16.
Excuse the typos. It was late and I was on a plane enjoying all the accouterments (pay per use wifi) of domestic coach travel.
CI's are the smart play for BP as they likely get in as collaborative therapy at minimum and possibly a primary therapy for some indications. Protein based CI are also somewhat easier to manufacture virtually any contract manufacturer can produce. The autologous aspect of dendritic and Cart-T makes manufacting more customized/specialized to get the things right is a area of expertise not found within most contract manufacturers.
Nice thought too and plausible with the shelf.
I'd be down (in favor of) with some head fake action......
True. The burden of innuendo has a low bar.
And Cenkos as we know is under investigation........you can't make this and lot of other stuff up with the wildest of imaginations......P5 was creative though.
Enron epitomized the "boys club". LP no matter the magnitude of spin not in the club......and as I recall the Enron boys club was brought down by those with the XX chromosome set.
I think most would agree. Albeit there are likely a few notable exceptions....
Deutschland. Sehr gut.
And we have affirmation.
Wait for it.....
Might be a little of what Captain is thinking baked in to make things right for certain investors in lieu if MFN. Per doingmybest's post earlier today we might just have a seat at table for some high stakes poker.
If this comes to fruition it will most likely be separate PR's as the vetting process gets exponentially more burdensome with partners involved. And said partners may be dictating when a PR is released especially if $'s are involved. And as noted by ic NWBO's cash position is a little light.
The cash position being the salient point.
Doc, Been there for while. Used Coca-Cola example in old post as trade secrets can be more valuable than patents and Coke formula is a trade secret.
Correct