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understandable, there being none ...
Amarin to present at American Heart Association Conference
by cincyreds57 ymb
Dallas nov 2013
Session: APS.202.04-Biomarkers, Lipoprotein Metabolism and CVD
Presentation: 19343 - Pharmacokinetic and Triglyceride-Lowering Pharmacodynamic Effects of Icosapent Ethyl (Eicosapentaenoic Acid Ethyl Ester) Across Clinical Studies
Pres Time: Tuesday, Nov 19, 2013, 3:00 PM - 4:30 PM
Location: Hall F, Core 2, Poster Board: 2016
Pres. Time: Tuesday, Nov 19, 2013, 3:00 PM - 4:30 PM
Specialty: +202. Lipid and Lipoprotein Metabolism: Clinical
Keywords: Pharmacokinetics; Fish oils; Hyperlipidemia; Lipids
Authors: Rene Braeckman, Amarin Pharma Inc., Bedminster, NJ; Harold E. Harold, Louisville Metabolic and Athersclerosis Res Ctr, Louisville, KY; Christie M. Ballantyne, Baylor Coll of Med and the Methodist DeBakey Heart and Vascular Ctr, Houston, TX; William G. Stirtan, Paresh N. Soni, Amarin Pharma Inc., Groton, CT
I think its wonderful how you take an interest in AMRN side shows :)
Everyone should. The more you know, the more it feels like doing a good deed.
AND it is so easy to keep it real ! The truth is outrageous enough, so no make believe necessary. Check out the ticker on the ymb for more useful facts
rofl or pratfall on an oily floor.
just sold a bunch of 2.08-2.10 that hadn't even settled yet.
hope this falls like a stone again, these stones are diamonds
Don Imus. LOL. Dr Picaninny, right ? I make sure to get all my med advice from Don Imus. And my life consulting from Howard Stern.
PS "Is AMRN making cancer cure claims? Seems I read that here on this board!"
LOL2X. classic.
One need to compartmentalize things; there are minor differences between an AMRM message board, and Amarin, the actual company. Breathe.
Jenks,easily funniest scam-label I ever heard of;
that CAPS are pharma grade, the CONTENTS are not LOL.
Think of the poor dupes stuck hard selling those pills and the rubes quaffing them. Thanks . Good eye.
bill , would you agree
there IS. Mine are used
LOL. soeww Nature has never been mined for substances, when isolated ( and ideally patented :) are far more efficacious than the folke remedy that proceeded or heralded them. In fact I still have on yon mantle top, a quaint willow wood mug, welle knowne to prefent and soothe thee heade achie and ill humour.
Head & Shoulders? What a load of dandruff. I sorta wanta see it; and I'm tellin ya all we need is now is a head, and another shoulder, and a consequent break either up or down, and it doesn't matter what planet yur from, we can sit back and ruminate how it was presaged. Unless of course this is the famed Quasimodo / Richtoffen pattern ... or unless we go waaaaaay back to a 4 month chart where wee see this is clearly a reversal H&S. or
same article, Eicosapentaenoic Acid (EPA) Reduces Cardiovascular Events: Relationship with the EPA/Arachidonic Acid Ratio.
Abstract showing up in Pub Med, US National Library of Medicine National Institutes of Health,
verifying in prepublication now, slated to come in
J Atheroscler Thromb. 2013 Sep 18. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/24047614
better than watermark on a pdf , I'd say
Conclusion
Dyerberg and colleagues examined the relationship between EPA and CVD, and the JELIS study recently demonstrated that EPA administration reduces the risk of CVD. An important difference between EPA and DHA is the metabolism of EPA to bioactive PGI3. It is assumed that, similar to PGI2, PGI3 inhibits platelet aggregation, vascular contraction, myocardial ischemic injury and arteriosclerosis and induces neoangiogenesis.
Therefore, it is speculated that the CVD risk reduction induced by EPA is also associated with the effects of PGI3 in addition to the numerous effects of EPA itself (such as TG reduction, inflammation inhibition and improvements in plasma membrane fluidity).
This hypothesis is confirmed by the following findings: an increased CVD risk was found to be associated with a reduction in the EPA/AA ratio, and the EPA/AA ratio was found to be positively correlated with the (PGI2+PGI3)/TXA2 ratio.
Block Trades Bought/Sold Ratio Net Cash Flow
23 ...............1.29...................... $307.50K
http://finance.avafin.com/stock/amrn?trades#.UL-d0uJodN0.twitter
A single block trade is calculated as a trade that is greater than or equal to 10,000 shares. The block trades screener gauges institutional sentiment for stocks. The net cash flow is calculated as the composite dollar value of buy side block trades minus the dollar value of sell side block trades. The bought/sold ratio reflects the volume of block shares that were traded on the buy side relative to the volume of block shares that were traded on the sell side. Figures are updated every 5 minutes between 9:30AM and 4:00PM EST.
Uptick/Downtick Trade Ratio ..1.11
Net Money Flow ..................+$308,322
http://quotes.wsj.com/amrn
Eicosapentaenoic Acid (EPA) Reduces Cardiovascular Events: Relationship with the EPA/Arachidonic Acid Ratio
J Atheroscler Thromb, 2013; 20:000-000.
https://www.jstage.jst.go.jp/article/jat/advpub/0/advpub_18002/_pdf
The clinical efficacy of fish oil and high-purity eicosapentaenoic acid ethyl ester (hp-EPA-E) for treat- ing cardiovascular disease (CVD) has been reported. Fish oil contains saturated and monounsatu- rated fatty acids that have pharmacological effects opposite to those of ?3 fatty acids (?3). Moreover, ?3, such as EPA and docosahexaenoic acid (DHA), do not necessarily have the same metabolic and biological actions. This has obscured the clinical efficacy of ?3. Recently, the Japan EPA Lipid Inter- vention Study (JELIS) of hp-EPA-E established the clinical efficacy of EPA for CVD, and higher lev- els of blood EPA, not DHA, were found to be associated with a lower incidence of major coronary events. A significant reduction in the risk of coronary events was observed when the ratio of EPA to arachidonic acid (AA) (EPA/AA) was >0.75. Furthermore, the ratio of prostaglandin (PG) I3 and PGI2 to thromboxane A2 (TXA2) ([PGI2+PGI3]/TXA2) was determined to have a linear relationship with the EPA/AA ratio as follows: (PGI2+PGI3)/TXA2 =?+p* (EPA/AA). Like PGI2, PGI3 not only inhib- its platelet aggregation and vasoconstriction, but also is assumed to reduce cardiac ischemic injury and arteriosclerosis and promote angiogenesis. Thus, the effects of EPA in reducing the risk of CVD could be mediated by biological action of PGI3 in addition to hypotriglyceridemic action of EPA. Compared with DHA, EPA administration increases the EPA/AA ratio and the (PGI2+PGI3)/TXA2 balance to a state that inhibits the onset and/or progression of CVD.
SolBarer buys addn'l 20Kshares 1day aft.prev.buy.
Sep 20 12:43pm
MDGN Medgenics, Inc. Barer Sol J Director 20,000 Purchase at $6.50 $129,996
Sep 19 03:22
MDGN Medgenics, Inc. Barer Sol J Director 20,000 Purchase at $5.57 $111,478
without a signed court order, I'm afraid they are gonna have to wait out side.
That should sound half familiar.
profound analysis, thanks
thanks. looks fascinating. will monitor
5800 ! Think of the lives saved.
is that 1vote for a dime,a $1ah,or damoon?
Not"against"it at~all...Problem; it's an unprofitable PR stunt,
and bamboozled shareholders are footing the bill, conned by the 'green' label.
We cant waste money on non solutions to serious issues designed not to fill needs but to fill private pockets. Old game, new players.
Wasting retail's limited capitol is perhaps worst than throwing another marker away. Business is not a charity.
Holy Hell Fire! Whats with all these RedVolume spikes today on L2?
Seems like nobody here to watch the shop anymore !
JBI getting ravaged.
Heddle already cashing out?
0.34. DOWN 7%. Ho Hum. Looks like JBI is expending minimal energy on its long suffering shareholders. Run! Its 'The Chart' !
I promised the wife I wont get pregnant
Mean ol FDA ...
oral gavage doses of 0.3, 1 and 2 g/kg/day ( ARE huge multiples of the recommended daily dose) Hundreds of times the daily dose is unwise. And pretty darn hard to swallow, like that warning.
Pregnancy Category C: There are no adequate and well-controlled studies in pregnant women. It is unknown whether VASCEPA can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. VASCEPA should be used during pregnancy only if the potential benefit to the patient justifies the potential risk to the fetus.
ker-SPLAT
good grieve, petcoke is like carbon (only dirtier).
Name: Carbon
Symbol: C
Melting Point: 3500.0 °C (3773.15 K, 6332.0 °F)
Boiling Point: 4827.0 °C (5100.15 K, 8720.6 °F)
Context: Those are really big numbers. temperature wise.
Comparison: Sun's Surface Temperature: 5,778 K
Melting point "plain carbon steel": ~1,130 °C
Schoolchildren shilled to promote sales of failing equity!
Don't educate them to critically evaluate and thoughtfully create,
rather indoctrinate them to servile widgits!
Crayola today PRed and promptly forgot its cynical “COLORCYCLE” marker program, which transports small boxes of used markers cross country to convert into net-loss energy & emissions. The program is the latest obfuscation in a continuing sham to advance stock sales. The “COLORCYCLE” marker program will allow students to meekly and obediently dispose of any type of used marker through an in-school collection process under the guise of keeping inconsequential amounts of plastic out of landfills. Once the used markers are collected, great expense and effort will be expended to transport and convert the markers into usable fuel at a loss.
whatwhatwhat ? we made liquid-phase carbon now? Thats SOME catalyst!
I'd rather have liquid carbon than a buckyball factory.
Its a crystallized particulate, becoming a suspension at best. Sublime all the volatiles, getter the impurities and collect low partial pressure components, and viola! particulate (very dirty, perhaps even a hazwaste) carbon remains.
I suppose if we could strike a plasma in the monster, carbon would go vapor phase too ... but I missed that 'feature' in the nawtec comix.
PS the liquid>solid / solid>liquid transition is reversible and thermodynamically neutral ( latent energy is recoverable) unless we just invented a "perpetual energy machine" in which case screw the oil, we solved the planet's problems.
I am left confused reading the lecture but I believe that actually refers to real-system heat losses, which added to the logistic costs of acquiring, transporting and processing feedstock basically dooms this venture to continual losses.
Now if we could sell a "perpetual loss machine" ... o wait a minute, JBI already locked that up approach. Without IP.
coming around to realize the 'catalyst" is a slurry added to mix, 30# or so per ton, halide getter. A lot of background info that says "old hat". It will collect in the petcoke and better be a useful alloying / refining agent or its not going in a furnace, instead of the ground. DDing this is getting boring 'cos the processor is so clunky and slow. nothing but a dangerously low volume swing down trader looking up for next brief moments
there's a brilliant analysis proving fuel consumed transporting markers was almost equal to fuel yield after pyro, then adding typical handling & overhead, the "recycle" was significant net loss. I'll look for it again, its been awhile.
But now that JBI is about selling processors, every elementary school could buy one and operate at-point-of-marker-dry-out. Think how much the small children will benefit from learning to shovel markers into a Monster , the school janitor could engineer, cafeteria ladies forklift ... I am ready to manage the operation myself
that explains $1million-in-stock booked @$9.997million asset, before being written off as worthless, unused. That stock swap is at least worth 320,000 at current levels. Wonder who holds it now?
Wasn't there some bad blood between the same parties on related transactions that lead to ANOTHER ongoing litigation? Updates ? Links?
Dir SOL BARER Buys 20,000 Of MEDGENICS INC at 5.57 on 9/19
http://www.sec.gov/Archives/edgar/data/1138776/000114420413051582/xslF345X03/v355477_4.xml
best boots/ground I've seen, hope this clarifies;
any SEC filings?
whatever happened to?
another 5500 lucky sellers hit the "UNCLE!!!" button.
Maybe they are just hoarding cash for the little bounces this one makes on the way down the stairs
Thank YOu ! I'm sure even in that crowd once they see facts we will have a certain number of intelligent new shareholders. Keep up the good work !
every successful company needs catalysts in addition to IP
yeah I am seeing 30+ lbs of catalyst per ton of feedstock. Any boots see bags of quick lime laying around ?
He sold a little over 66K. He possess over 382K after.
He cleared a buck.20/share or under $90K.
After taxes that should be a damn fine kitchen remodel and new econocar.
http://www.sec.gov/Archives/edgar/data/1392380/000118143113049783/xslF345X03/rrd390826.xml
whatevah happened to good'ol OxyVinyl ?
I thought that was a heaven made match up.
Then again, those days, JB was claiming to be >< this close to operating processors in two locations.
DD. Learn. Do.
heres a freebie starter kit
catalytic pyrolysis of plastic wastes
About 129,000 results (0.29 seconds)
Could actually be a zeolite, but I'm sure you already considered that., in which case I am sorry to bother you.
...A very good example is the zeolite ZSM-5. This zeolite, developed by Mobil Oil, is an aluminosilicate zeolite with a high silica and low alumininum content. Its structure is based on channels with insecting tunnels. The aluminium sites are very acidic. The substitution of Al3+ in place of the tetrahedral Si4+ silca requires the presence of an added postive charge. When this is H+, the acidity of the zeolite is very high. The reaction and catalysis chemistry of the ZSM-5 is due to this acidity.
...Catalytic pyrolysis/cracking—The feedstock is processed using a catalyst. The presence of a catalyst reduces the required reaction temperature and time (compared to thermal pyrolysis). The catalysts used in this process can include acidic materials (e.g., silica-alumina), zeolites (e.g., HY, HZSM-5, mordenite), or alkaline compounds (e.g., zinc oxide). Research has shown that this method can be used to process a variety of plastic feedstocks, including low-density polyethylene (LDPE), high-density polyethylene (HDPE), polypropylene (PP), and polystyrene (PS).
Get me 1 cm^3 and I will tell you alllllll about it ;)
Pyrolysis Works! Just not net economically
The process of pyrolysis creates residues including char, silica (sand), and other bottom ash. Some of these residues can be reused while others must be disposed of in a landfill. One major problem is the amount of residual waste produced that may call for landfill disposal is about 15- 20 percent of the overall feedstock used in the process.
The leachability characteristics of ash will need to be assessed, and specific linings will need to be used in the landfill that this waste is disposed in.