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Fantomphan, this week, it seems the traders have not been running for the exits during the last hour of trading, and the short interest daily volume has also been a bit lighter than usual. It is also starting to sink in that the situation with Covid-19 my not be such a flash in the pan, that it may continue to stick around and flare up here and there as time goes on. We offer one of the few legitimate life saving treatments to fight this virus in critically ill patients and it seems we will have to make an investment in the companies infrastructure in order to keep ahead of the demand. That and news regarding several trials and other opportunities seems near at hand.The pps seems to be responding to the near term positive outlook. Next couple of weeks looks positive... could give us the opportunity to stretch our legs a bit... U all have a good weekend...
Mike, Your theme song can't be from "Rocky"... Maybe "Short People" by Randy Newman?
Are replays going to be available for us to pick through? If I heard right, Germany is trying a smaller device that is still clearing the drug up to 95-99% removal after 4 hours? I need to listen to this again. Very exciting stuff. If the filter is much smaller, I'm also thinking infants and toddlers. Wow! I am very pleased with where this seems to be heading!
B52, Hemo, I have felt the same way, becoming frustrated with the pace of a product that has such potential. Lately, I've also been thinking that we could be held back because of supply limitations. If we are currently manufacturing the filters at close to maximum capacity, how are we supposed to be able to supply expanding markets and additional therapies? We are kind of between a rock and a hard place, needing more capacity, but also needing the market to justify the expense. A good problem to have, but we must meet the demand when called upon. Our patients can not wait because the filter is on back order. I would like to have Dr. Chan address this problem. What is the value of Cytosorbents now at or near maximum capacity?
I don't think Cytosorbents will PR something that is not of their ownership or control. They will PR results of their own trials or material events but not so much if it belongs to someone else. That would be like I walked over, picked up your trumpet and started playing it without asking your permission. You just don't do that... I'm open for correction on this.
Stingman, Apparently "Marty" mixed two separate points together, the 1000 person study is not the same as the 100% survival study.
https://instantscientist.com/cleaning-the-blood-of-1000-icu-patients-in-the-largest-covid-19-trial/
TwoNE1, This might help...
https://pubmed.ncbi.nlm.nih.gov/32252114/
"Combined Use of CytoSorb and ECMO in Patients with Severe Pneumogenic Sepsis"
Fantomphan, I prefer your style of communication, more expressive, colorful, great for emphasis. I also respect the perspective and intelligent thoughts by Hemo. I take a little from each of you and wish to see some serious revenue from Covid applied toward the most promising solutions, to slingshot us toward the success of this wonderful product.
Pete, I hear you, and yes, nobody wishes misfortune on anyone, especially with permanent consequences. I prefer to view this as most here do, that Covid is another application that happens to be here and now, one that is quite treatable as far as our filter filling a gap of a very serious stage of the illness. I'm thankful for that. I also believe we should take an aggressive stance when promoting the benefits we offer to this pandemic. There are several ways we can fill the short fall of filters. We need to build a rotating inventory, if that is in fact possible at this point in time while expanding our manufacturing capacity. Look to J&J or others to help fill an immediate need for filters? I don't see Covid going away anytime soon. I believe it will continue to march through the worlds population, flaring up with opportunity, and more concerning to me, this virus mutating over time so that the vaccinations we do come up with lose their ability to target Covid. This is not going away soon and we fill an important step for 10-20% of those contracting this disease.
We need a capacity at least 5x our current capacity to stand up and be counted as a serious player in all that our filter offers.
Mike, I empathize with you, I've been here 12 years or so, would like to sell out, buy my last home I intend to live the rest of my days in. Now, not sure if I will live long enough to see that plan become reality. We all have choices though. I agree Dr. Chan is a scientist and therefore programed to give the facts, just the facts. He is not a salesman who has the ability to sell anything, without "stepping over the line" as far as ethics goes. Two different styles. I promise you, Dr. Chan does care. He has brought this company a long way without diluting us nearly as much as he could have. That's one of the differences between a shiester and a real CEO. I'm staying too, but I have also watched other stocks multiply before my eyes that I had considered. EXAS for one, 5 to 120 in two years. So, lets hang in there, we know this will do well. Perhaps Dr. Chan will give our new CMO an opportunity to speak for the company publicly as time goes on. Best to you and all the rest of the committed longs here. Come on Bertha, throw us a meatball!
So, it has been the typical market reaction to good news, this time the annual report, and then for a few days the stock gets hammered. Three times I've ridden this roller-coaster. Started buying in my 58th year, I'm now approaching 71. I'll stick around a little longer, but I have to admit, I am getting a little long in the tooth! Speaking of sticking around... We could use some good news generated by a well known celebrity being snatched from deaths door. Lets shine a light on what we can do! I'm thinking, Nick Cordero, the Broadway actor/dancer who has been on social media, going 51 days now in the hospital fighting for his life, with covid-19. I have tried to contact the writers of a couple stories that has come out about his fight, and his wifes' website, to give them a heads up about Cytosorbents filter. If anyone else has any ideas as to how to get his Docs to look at our filter, this could get some serious good news publicity going our way, if he's not already too far gone. Best of luck to this couple... On another note, I do not understand how a company that has so much going for it has 20 to 25% of its volume shorted, day after day. If someone has a reasonable explanation for this, I'd love to hear it. In the mean time, I'm sticking around, there's a serious bump around here somewhere! GL longs...
B52T38, It was mentioned in the 10Q that we have a back order of 2500-3000 units. That says there are no filters on the shelves waiting to be shipped, and they're making them just as fast as they can to keep up with the growing demand, not only from Covid-19 which was a classic Black Swan Event, which we just happened to be perfectly aligned with but with all the rest of the reasons to treat seriously elevated cytokines. I will expect to hear news, probably on the next conference call, that breaking ground on a new manufacturing plant that will be capable of supplying our needs well into the future is in the works. My thoughts regarding capacity? This facility should be capable of manufacturing all the different designs we need and deliver a minimum of 1 million units per month of our primary filter. That sounds like a lot, but not in 5 years. With this Covid-19 we almost got caught unable to deliver the goods and we still aren't out of those woods yet.
Hey Big Guy... I remember you too.. I think you used to get into it with Kissmyask... or was it "bitemyask"... Welcome back... You're style will help pick up the slack that losing Bertha caused... I also wonder what became of Ping... was always on point... Interesting times ahead, I haven't sold one share in ten years, big weakness, I know... I really believe we can hit the ball out of the park in selected areas here. Looking forward to our future.
Yes, Just like the CE approval says, approved for elevated cytokines.
Mikesmith... Overlay CTSO onto Nasdaq chart or the DOW for that matter and that will help explain the movement today... if the Nasdaq had a strong day today we could have closed above 11. Patience, this stock is golden, it's a new solution to an old problem and it's taking a long time to sway the opinion of the "Experts" because it's not an injection or a pill, but they can't deny our filter is working when all else fails, and that is beginning to catch their attention. We are manufacturing filters 24/7. There is a reason for that. We will need more capacity fairly soon to keep up with the demand.
Actually, if my memory serves me correct, we started out charging $500 per filter. It wasn't too long before we went to a boat unit. ($1000. Average cost to do anything on a boat).
Burnttoast and Biomed... Both of you have pointed out that both the distributor and the hospital also need to make a profit... So the figures that Dr. Apostolescu may have been quoting could have been the cost to the end user?! The Patient? Okay, the cost for the filter, at least as it pertains to us, would be our price to the distributor or direct sale to hospital, $1000 each. That's not what the end user or the insurance company will ultimately see. My bad... I may have been overly concerned without thinking this through...
Techxen, I scrolled through the information offered in the link and although I saw the line regarding the filter, I could not find the number of filters ordered nor the cost associated with them. Reason I bring this up is the article that Yielddude posted, towards the bottom included the following:
"CytoSorb has been used in a few cases, under 10. There were no funding problems, but patients must have an indication of that. Only so many had," Catalin Apostolescu, spokesman for "Bals", told Freedom. We've been using this procedure for a long time, long before COVID-19 comes along, it's not a new thing. It's really very expensive. A filter can cost between 2,000 and 4,000 euros and, depending on the patient's condition, you may need two to five filters. Costs dry you out, but to save a man's life, it's worth it. Dr. Catalin Apostolescu: Freedom asked Catalin Apostolescu and if he could confirm that P.S.P. Pimen was treated with CytoSorb: "No comment. Details of the treatment of a bye are confidential
Read the full story: EXCLUSIVE. Along with 20 other Romanian patients in critical condition, P.E.P. Pimen received a revolutionary treatment for COVID-19: blood filtration against cytokine storm".
This concerns me in that if the cost quoted here is true, then once the filter is sold to a distributor, we lose the control of what will ultimately be charged for the filter. There is something seriously wrong here, in that Dr. Catalin Apostolescu lends legitimacy to the quote of 2-4k Euros per filter which he justified with the quote "Costs dry you out, but to save a man's life, it's worth it." The last thing we need at this early juncture of our company is a scandal regarding people ripping off others in dire need of our product by charging 2-4 times the going rate! There may be a bad apple in our distributors list that Dr. Chan may want to look into.
CC; Dr. Philip Chan
Lakersrback... Two points... How does it happen that your post #22637 makes reference to my post 22638? Did you edit your post after I had responded to your question within the 15 minute window? My response to your request for information, "anyone remember what took the stock to over $15 a few short years ago?", I gave you my honest opinion on why the two spikes you were asking about were typical Pumps and Dumps. There were no 10-Q's or 8-K's during that time frame. There was a fairly rapid rise in pps, then it fell off a cliff. Twice, losing better than 40% of it's value on opening from the previous close. All on no news. Classic P&D. What would you call that? Further, your comment, "Why is Toronto Raptor Rob calling CTSO a P & D? He should listen to the transcript!" Well, you got that wrong also, I'm sorry I responded to you, however one positive note did come out of this exchange, you exposed yourself as someone who does not quite rise to the qualities we would hope to see in a just and fair moderator. This whole exercise was kind of slimy, really. My apologies to the lluminatenorden.
Pump and Dump
Canes... That is a substantial percentage of ATM sales. Do you think that has been part of the reason we have felt the pps has been struggling not withstanding all the positive news?
Techxen! First of all, a wonderful quarter for us. This and Q-2 may be looked back on as the springboard quarters. Putting many of the trials and research on hold in order to cope with and focus on the greater need is a good thing. On top of this, we have signed a player to our team who's intellect is obvious in the ease and clarity of his communicating technically what we are about, to the average "Joe". I suspect we will be hearing much more from Dr. Makis Deliargyris as time goes on. Dr. Chan, you have picked a winner here. Congratulations on your great quarter and your selection of Dr. Deliargyris as our new Chief Medical Officer!
Sweet! Up 75%+ across the board. Very, very nice!
Techxen! You gave me a laugh with your peeing in the pool comment... I never did because I was told a purple cloud would form around me and everyone would know what I was doing! Thanks for the laugh!
Be nice SABAI... I tend to agree with the choir here, it would be a dereliction of duty for Dr. Chan to stop orchastrating Cytosorbents, Inc. with all he has on his plate, in order to fill in all the minuscule details when with a little dd you could inform the rest of us of your findings, which, by the way is the primary reason for this board to exist, no? Cytosorbents is really starting to unfold to the world, and there is a lot more to come. Sit back and enjoy the fact that you have a ticket to ride here...
Murph, If you click on the description line of each picture there is further dialog explaining the source of the photo and what application is being treated...
Couple reasons to accept stock options and stock as part of terms of employment. One, it keeps the cash flow lower as far as retaining qualified personnel. Two, the key players in a business have some "skin in the game", and in the case of a young, growing corporation, the returns are potentially much greater than if your compensation was cash only. So, Vincent is in his 60's? Maybe he wanted to out-gas on a fishing boat or whatever... Some times stock is sold in order to cover the taxes due on the issuance of stock as compensation... In our case, its payment for services rendered.
Ah! I was wondering where you got the hair! It's been a very good run from the third week in March, just letting off some steam, then we'll put the clamps on the shorts for another couple weeks. This has a ways to go to get to where it should be...
I too was very pleased to see the accomplishments our new Chief Medical Officer has to his name. Not only that but I'm sure Dr. Deliargyris is well respected over at FDA and that certainly doesn't hurt either!
Stingman... If I were you, I wouldn't chance it. The 3 1/2 minutes you would have to take your eye off the computer screen... That could be a very expensive happy life moment, AND, she could accuse you of lying!
It was a long wait, Sabai... Now what we need is a series of excellent responses from some very sick patients. Let the word spread!
Hey, Shorty... I didn't read that, I read the manufacturing facility was operating 24-7 trying to keep up with demand. What may come out of this is a BARDA financing in order to expand our manufacturing capacity by a multiple of 5, which we will need to do anyway for the future demand of our product.
Hello Robroaster, that is a noble target, 1-2 B. Works out to 30 to 60 dollars a share. I'm curious, how do you see Cytosorbents reaching that goal and what is your time line? I think your lower estimates are within reach, I don't know if I will live long enough to see the 50-60 pps. I long ago worked out a critical path for Cytosorbents, and have since looked at many opportunities come and go with time. I have stuck with CTSO, however I am way behind my original estimates as to where this stock would be around this time. I thought we could hit 20, so my original sell point for 25% of my holdings was set at 18.60's. Valuing Cytosorbents using price to sales ratio puts us at 10.50 or so and I believe a double from there, (near triple from current pps)is reasonable within two years or sooner, IF we gain acceptance with the proper medical professionals.
Murph, the more we mull over different uses for our filter, the brighter our future appears... "Died from 'Complications' of the flu". How many deaths due to flu in this country alone? Really?
Murph, about a week ago I happen to mention that dialysis centers could be a source for spare blood pumps.(post# 21071). I did not intend to suggest using these centers to treat seriously ill covid-9 patients. That would probably wipe out 75% of the dialysis patients. The machines could be collected, checked out and sent to a facility, safely set back from adjacent populated areas, with negative air pressure filtered and UV treated to outside.
At the beginning of the presentation Dr. Kellum mentioned there were more than 1600 people who had tuned in.
Jacquescode... During the Cowen interview last week, Dr. Chan in response to a question regarding capacity, started to answer "80 to 100 million d". He caught himself, and changed his answer to reflect 80,000 filters annually, but he also said they were not producing at 100% capacity. It is speculation on my part, but, if he did start to say 80 to 100 million dollars annually, that would work out to max capacity build out of 280 units in a 24 hour shift. It is good to hear that there is room to expand if need be, and I think that is why Dr. Chan mentioned ongoing talks with I believe it was BARDA.
Careful Mr. Canes... Mr. Lamersback might accuse you of bullying... The recent decision in Italy, to add Cytosorbents filter to their Standards of Care for the treatment of Covid-19, as it relates to AKI, can be found at https://www.era-edta.org/en/wp-content/uploads/2020/03/COVID_guidelines_finale_eng-GB.pdf. Go to Section 6, pages 11, and Appendix 7, pages 12 and 13. That could be an effective inclusion in heads up e-mail to organizations and people on the front lines.
Green, I scanned the information and I don't believe we are in the guidelines. I keep thinking that although we are trying to "help out" Cytosorbents by bringing our filter to the attention of professionals on the front lines, I would refrain from getting too technical. Perhaps an e-mail, a heads-up that we are here, with pertinent contact information for Cytosorbents, including current trial results to the proper people responsible for these organizations. To send a complete sales pitch would be inappropriate for share holders to do. I would think Dr. Chan would like approval from FDA before expecting inclusion for USA in their guidelines. I would hope our sales people have been in communication with the operators of ECMO units where currently approved.
Probably not a whole lot... Who would be the targeted audience? Certainly not those in need at the time of airing... So, potential investors? Could get some free exposure by calling in to the Mad money since the FDA EUA.