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Today IMO is the shorts last gasp attempt to spin a PR, namely the S-3 shelf filing, as sounding negative when it is quite positive. They must be sweating bullets and they already see that they are going to be stuck with a navy (much more than a boatload) of sold shares to buy back which will be near impossible to acquire except at a very steep price..
Future PRs should all be quite positive with little wiggle room to spin IMO.
Very happy with the news of Fri and today. Expect to see share price recover quickly and I hope more and more shares are being taken from the traders and into the hands of investors.
The world needs Brilacidin, if it doesn't work I think we are in a very large quandary with little way out.
Not a great start to the week, but the race is not won in the first couple of strides out of the gate. We have the horse, the pedigree, and now the financing to see this race thru to the end.
Good times ahead!!
Your statement that you are here to save us from ourselves was the clincher. Adios, multi-ID.
List the companies you follow and I will check up on their PRs to see how they are identifying the labs and hospitals doing their testing and trials.
I can't name any that have not named their sources as I don't delve into others that deeply. Most BPs use their own labs, I guess that is why we are seeing so many failures from their efforts, and small bios are in the same status as us so they are the ones I am interested in.
Name one company to date that listed such information for their trials.
No need for such data to be given and I seriously doubt it will be.
Investors realize it is best for impartiality and undue influence from possible ne'er do wells that such data be kept secret.
Clinical trials are not like self-serving politicians that cater to any cockamamie requests from those not needing such information.
Hard for me to believe a supposed investor needs such constant proof from the company that they aren't just throwing BS to the public. If one is so scared of a scam, this is not the place to be.
What scenario can you even conceive of where the data to date on Brilacidin trials in ALL TRIALS is not true?
IPIX doesn't make up the data, it is reported to them by the hospitals running the trials and the governmental labs running the tests.
Edit: Just read your msg saying K would be introduced at the right time to your daughter.
Great about your daughter and B, but being an oncologist has she had any introduction to Kevetrin yet? Is she aware it activated the p53 gene? This should be way more interesting to her than even B and CV19.
Have no clue as to what goes into finalizing the tox tests for the Kevetrin pill, but as soon as that gets done Kevetrin should be in quite a number of trials as a complementary adjuvant to current cancer treatments.
Maybe her medical center would want an early advantage in trying to be the lead center for advancing Kevetrin in trials .
I agree with those that are of the opinion that naming the investigating site would do no good and, in fact, could cause problems with investors/lobbyists/others bothering these people and cause them to delay their work.
As long as we keep getting good news as to testing, I have no need to know who is doing the testing.
Didn't IPIX submit grant request to BARDA in Feb?
How many PAN-CORONA grants are they seeing, especially submitted jointly with an RBL?
IMO, for all the back slapping BARDA seems to get, IMO they have been sitting on their ass regarding being on the cutting edge of new treatments.
Not really sure I can enumerate who they have given funds to so far, but my general feeling it is to useless BP repurposing drugs only.
Bottom line: Not impressed AT ALL with BARDA to date. Bureaucratic log in the road IMO.
What basket is that?
They are moving forward on CV and UC, who knows w/ OM or even finishing up K (oral)?
Many irons in the fire, all hot IMO.
I believe there is a beehive of activity around Leo every day, at least in regards to entities getting to know IPIX/Leo better and positioning themselves for soon to be activity.
Just for the record, I can't recall Leo ever mentioning a quiet period or NDA since CV19 started in Feb. Many of us have assumed this is a CDA situation concerning investigations, but Leo has never mentioned it or used it to escape any kind of transparency.
From the way CV investigative information has been given, that being it usually takes us all by surprise (except for the known testing of human lung tissue ahead of time), it does appear that Leo isn't chomping at the bit to put out PRs until there is something worthwhile to say and which seems in line with what the RBL/govt is fine in him revealing. IMO.
My rant for this evening:
RBL and IPIX waiting for grant to proceed on a PAN-CORONA virus investigation. So what is the RBL doing while waiting for such grant? I thought very few drugs showed promise of killing CV19 so I find it hard to believe they have a large backlog of drugs to check out. They have a mass of info now showing which classes of drugs cannot be "remanaged or repurposed" to work against CV19 so they can probably tell which have no chance before they even start. So what are they doing?
You would think they are going hellbent-for-leather into further research of Brilacidin and whether it does indeed have a full spectrum of coronavirus benefits.
As for costs, I would imagine the costs for the RBL are all basically fixed or sunk costs (lab employees, equipment, building, etc) and they are given the Brilacidin for free and most likely CV19 virus for free so their costs are nearly minimal to continue exploring Brilacidin deeper, such as working more on encephalitic inflammation, bowel problems caused by CV19, additional lung work, or even start looking at how it works against various Flu strains and possibly HIV.
So are we really waiting for money (since some say IPIX could only use this money for RBL investigations) or are we really waiting for higher ups to give RBL the authority to investigate Brilacidin in its entirety? If that is the case, then I hope to God that politics and "big money" payola doesn't land Brilacidin in the never-never land of purgatory never to be heard from again. I don't see how it could as IMO the RBL researchers would most likely become whistle blowers and many heads could roll if found they sacrificed many American lives and the economy for personal reasons.
No way I see the govt taking any break in investigating Brilacidin to the fullest if they are truly intent on ending the CV19 threat.
Expect news very soon. This crap about them needing another month or more doesn't fly with me either to providing grant money or keeping it under wraps and making it go thru dog-and-pony show trials that no other drug had to go thru that have been given hundreds of millions.
As for the BP antibiotic program, they already knew about B-ABSSSI and I don't think IPIX will see a penny from them. Pure false front being put up by BP and totally full of (not shinola).
Seems B has gotten little attention to date.
Makes one wonder just how many drugs have come down the line that killed 97% of lung tissue CV and 85% of kidney tissue CV, are extremely safe, and have been tested on hundreds of patients in actual trials for other indications to date?
Obviously for the USA and the WHO and medicine in general, they have no viable filter to put the really hot drugs onto a fast track. The system seems to be near useless from what I have seen as to progress to date. They can't even tell a pure sham play (as in Moderna) from a true new-science play (Brilacidin and defensin mimetics).
Example: This SI ratio we are waiting for - Why the hell is that important? Why is it holding things up?
Brilacidin has already shown it works in patients with no negative side effects. Pure bureaucratic BS IMO. Might be nice to know, but not to the extent of holding anything up.
Hard to tell what the number of new cases mean as the criteria for listing a patient as CV19 keeps changing so quickly.
All I really care about is death rate and if hospitals have enough room for critical patients and just what they are doing for those patients.
Total number of cases IMO borders on irrelevant as the vast majority are no more severe than a cold or the flu.
The Pebble Project in Alaska is likely to finally become the largest new mining site in the world with enough copper to provide the USA with a 30 yr supply, plus enormous reserves of gold, silver, and manganese.
They have been trying to get past OSHA for many, many years and once they get govt approval it will likely take 5-6 yrs to get operations started.
So would you say to walk away from such an important mineral stockpile because it is going to take 15-20 years to get going from the time of discovering the porphyry?
Why would anyone start a winery since they normally take quite a few years to get the grapes growing and in large enough volume to make a go of it?
Quit living in the past. Who gives a rats ass how long it took to get us to where we are today? Only thing that matters is how long will it take to get us FROM HERE to COMMERCIALITY and that appears to be on the very near horizon to maybe a year or two.
Your point reminds me of the following story:
Sure, there are Claiborne Farms and other such behemoth Stud Farms that turn out lots of great horses out of elite studs and mares,
while
Mrs. Penny had but a one horse stable.
BUT that horse was SECRETARIAT
Likewise, IPIX has but a 2 horse stable but those drugs include Brilacidin and Kevetrin
Why do they need a massive organization of paper pushers, why do they now need a large R&D dept, why now do they need lots of employees, or any of the other brick and mortar features of larger biotechs?
AS for a board of directors, I am loving that we do not have a bunch of high priced yokels and instead we have a CEO that has more skin in the game than any other stockholder so he is working for his fellow stockholders instead of the management team.
They can add temporary clerical workers, medical officers, etc as needed. Personally, I wouldn't trade our setup for any other as long as we have the 2 drugs that we currently own.
Am I correct then in thinking we have 3 MOAs to either kill or stop replication of the virus and an additional 2 MOAs to stop secondary results of the virus which has caused many other CV patients to die?
All in all, quite a show-stopper.
In your estimate do you think there is anything out there currently being investigated that even comes close to having the range of attributes that Brilacidin has in combating CV19 (or whatever mutational form it is now in) and all the secondary effects of it?
If there is that great a push for an answer by medicine/govt for CV19 there has to be someone at a high enough level to have delved thoroughly into Brilacidin IMO to have the same understanding of its viability as the "go to" answer to CV as is known on this message board. Cannot give ANY reasonable excuse as to why they would not know about Brilacidin and be all over it to rush it thru trials.
Is the below excerpt from your post an error or did we acquire an additional 2 MOAs recently? I'm thinking it was just a really fat finger.
--------------------------------------------------
"Brilacidin is unique in terms of safety and 5 mechanisms of action"
So why weren't you upfront and disclaimed you are only here for CV and that is why you want the company sold quickly and for the amount you stated? I would have found that impressive and understandable.
But what you did is what I consider BS manipulation, making people think that price would be a good deal without also mentioning down the road the return could be monstrous, but you weren't hanging around worrying about that?
Guess we all have our own set of ethics.
All desks, chairs, walls, clothing, bandages, catheters, wipes, etc.
The possibilities are endless
I would venture greater than the medical possibilities.
But we will never know if we sell out as some keep advising.
Brilacidin for medical purposes inside the body is the small molecule form of the drug. In the polymer form (many small molecules linked together)it can be added to plastics, paints, textiles, etc. to form many industrial products. It has been posted recently that IPIX still has rights to the polymer related applications.
It could help revolutionize the world against many bad things, medically speaking.
Very commendable outside the box thinking!
For $1.6B, I can understand it taking 2-3 months for grant approval.
For $100MM to get Brilacidin started with further investigations / trials, a month should be enough time and they could continue considering the grant for LOTS MORE MONEY without holding Brilacidin up currently.
The longer Brilacidin is held up, the more people are dying and economies around the world are going down the tubes.
Brilacidin pill for general health not such a long shot as we already have shown we (with BDD technology) can make a pill that dissolves in the colon (large intestine) so all we would have to do is make another pill to dissolve in the small intestine as that is where most food absorption takes place in the body. Shouldn't be hard to do IMO.
The PR shows robust results also IN VERO (in animals) testing.
Another box checked. It works in a petri dish, it works in animals, it has shown excellent transfer of expected results to humans thru the ABSSSI trial, so the CV19 human trial should be a pretty good bet to turn out quite well.
Now have money in the bank, no further dilution expected to raise immediate funds, moving forward on all fronts, good news all around.
Nice PR. Better to come IMO
You seriously are worried about Brilacidin getting a grant?
Are we also to worry that the sun is going to rise tomorrow?
Even after the CV19 play, many longs feel that IPIX will STILL be the best chance (or at least one of the very few top chances) for further meteoric price increases. They may take off a portion of their total investment returns to date from CV19 so they can live the good life now, but why should they continue to chase the golden goose in other investments when IPIX will still continue to lay golden eggs? IPIX should always be a cash cow revenue generating Goliath!!
I believe ALL should have a definite core position that is never touched (until it reaches what the investor believes is the get-out point) but that a trading pot of funds should also be used to play spikes and valleys.
Remember, even after CV19 we could still see a MAJOR play for the FLU, HIV, other viruses/viral adjuvant uses, Ebola, encephalitis, COPD, Asthma, burns, kidneys, GI tract (need I go further?). Notice I didn't even mention Kevetrin.
Quite an investment, quite a ride, quite the benefits for the world.
IMO IPIX will become somewhat of a BP themselves just as did Regeneron.
IMO a once in a lifetime opportunity.
Sad that so many were intent on seeing it fail. But in the end, science and a world in need will see it thru to success.
What if the funding news says that we got a good amount of funds for a PAN-CORONA investigation?
That should set those with any idea about medicine on their ear.
Leo isn't the big shot calling when PRs will be allowed to be released or what news is authorized to be put out in public IMO.
If the govt says keep your mouth shut, Leo acts like a mute.
If govt ties funds to "tight lips", Leo acts the mute.
I am so happy for this week because no matter if Brilacidin is named as "The One" or not it will still have taken a major step forward simply by the BPs getting together for a Big push on antibiotics and the govt switching from all its efforts moving away from vaccines and more towards therapeutics.
At This stage, Brilacidin doesn't HAVE to be "The One".
But in time, it will become "The One". I certainly don't think any BP has been sitting on a drug with the potential of Brilacidin over the last couple of years. They would have had it going thru clinical trials with a jet pack strapped to its back. Thus, I can't really see any other drug out there currently that has ALL the advantages of B in terms of triple ANTI, triple MOA to kill viruses, safety profile, and has had results anywhere near what B had in both the kidney and lung tissue tests.
I like our chances for success. It doesn't have to be this week, but it sure would make for a GREAT summer!!!
If you are adept at chart trading to any degree you must have made a killing in IPIX by now as it seems to be a very good stock for such purposes.
I am not a chartist, but why would charts even come into the picture if Brilacidin does indeed turn out to be the big announcement by the govt this week? Even the govt says it should be a "market mover" and how many times has that happened in our lifetime?
People have laughed at possible share price numbers put out by longs since 2011, but it seems that those numbers are now looking quite reasonable if indeed Brilacidin performs in so many areas of medicine that it currently appears possible to do.
If Brilacidin is not the big announcement, even a mention of it and the resulting grant(s) and the results to date should throw the chart reading out the window IMO.
I know many won't take the risk to ride the dragon and will happily sell out as soon as they make 30%+ on their investment in IPIX, but for those willing to believe what they have seen thru govt clinical investigations to date the rewards should be multi-levels higher.
What does Medscape have to say about Brilacidin, if anything?
Just wondering, did you go to the NitroPep+ board and put up the Brilacidin scientific workup from the IPIX website to show them what they were up against?
What were their results in the kidney and lung tissue tests?
The only reason I see Remesivir has been pushed so hard is that 11 of the council members in charge of CV19 have an investment interest in Gilead Pharma. Absolutely no other reason they thought it was a world beater when they started development and guess what, it is far from being even a satisfactory refuge until a real answer is found for CV19.
I heard today on some talk show that the government put in $85MM for its development and then Gilead turns around and charges an arm and a leg for doing next to nothing. Again, can only believe the price is what it is as those 11 council members want to make sure their investment shows quite a nice return in their pocketbook.
Do I sound jaded? Damn right I am, but that is how those in power seem to work nowadays, especially in government. Make me some money and screw those that I am supposed to be working for.
MY WAG
You sure you got the right indication mentioned?
I see your point now, as I did after I had already posted and my edit time was over and read your reply to others regarding your statements.
I do think, though, that Leo could assure govt that experts would be brought in for needed expertise for human trials, though these would most likely be done with top hospitals and with the input of govt medical experts (wouldn't we expect the govt already has a basic concept of the way a major human trial for CV would have to be set up as to end points, safety limits, etc so it wouldn't be left completely in the hands of non-govt persons), etc. as was stated by JFM in an earlier post.
My contention why we haven't seen a grant yet is COMPLETELY due to the size of the grant being considered. A small amount, no problem, but a grant to cover a PAN-CORONA that could also be encompassing the flu, HIV, Ebola, encephalitis, and all other types of viruses with the proper care taken to validate such a world-changing drug would require a definitely high amount of money, maybe in the hundreds of millions.
It's not as if every other drug is now knocking it out of the park. In fact, the shelves are looking pretty empty in the cupboard of possible CV19 treatments and vaccines. I think they now realize how encompassing a drug has to be to be able to be effective against CV19 and that Brilacidin may be the only option that covers all those requirements and they don't want to screw it up as to investigating it to the max. Hope I am right in this matter.
And did you MBA-mind fail to realize the CV investigations will be administered thru RBLs and run at the top hospitals? It is not like IPIX has never run a prior clinical trial.
And the way govt has thrown around money to worthless BP pipelines, it doesn't appear the waste of tens of millions of dollars would put them out much, either, should they fund B further investigations and they fail.
You did a job on Leo, now try and do a slam on Brilacidin.
Doubt you will get far before realizing it is the real deal.
But I think you already know that and that is why you slammed Leo.
Those who know what they are invested in do not worry about your slings and arrows, they are but paper shams.
I actually believe grant money comes in much quicker. My aug/sep date was for us to start a human trial and possibly have some positive signs from that trial by the end of sept.
I realize most here are now traders and a week seems like forever to them, but for investors 2-3 months to determine whether you are holding onto a wonder drug is certainly not too much to ask for in terms of holding onto your shares.
I have all the confidence in the world in B, but the timing is anyone's guess. I am assuming sooner than later as there is too much riding on B progressing, both in medical and political arenas, for govt to sit on it for any period of time. IMO
lack of money is/was the only reason we are where we are today and not bringing in big revenues already. that is about to change. time to forget about last year(s) and get onboard with what is happening today.
my recommendation to everybody would be to sit tight until at least aug/sept. expect major news prior to oct. in the cv realm. simply my WAG.