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Thank you iwasadiver,
The man is horrible.
GLTU
Thank you sentiment.
GLTU
Thank you for sharing muee88.
GLTU
Congratulations reg2015 !!
All the best to you.
Thank you Bright Boy.
Great post and so true.
GLTU
flipper,
I am only an amateur, but the moment I see thr word mesenchymal somewhere my attention is drawn.
This has become such an important word in this trial.
Thanks for all your lessons in this area flipper !
Best to you.
100% AGREED !
GLTU
Good post, thanks.
GLTU
driving a transition toward the mesenchymal subtype.
Do you have a link for me showing first and second endpoints mOS nGBM and mOS rGBM ? .
Thanks in advance.
Thanks flipper.
All very interesting and fully agreed.
For now the rGBM is a very important item.
GLTU
X Master,
It is OS NOT mOS in both cases !
BIG difference.
E.5.1 Primary end point(s)
The primary endpoint of this study is overall survival (OS) compared between patients randomized to DCVax-L and control patients from comparable, contemporaneous trials who received standard of care therapy only, in patients with newly diagnosed glioblastoma.
E.5.2 Secondary end point(s)
The first secondary endpoint is overall survival (OS) compared between patients randomized to placebo who received DCVax-L treatment following disease recurrence, and control patients from comparable, contemporaneous clinical trials, in patients with recurrent GBM.
GLTU
Thanks pgsd.
It's always good to read Bigger's opinion.
GLTU
Xmaster,
E.5.1 Primary end point(s)
The primary endpoint of this study is overall survival (OS) [color=red][/color]compared between patients randomized to DCVax-L and control patients from comparable, contemporaneous trials who received standard of care therapy only, in patients with newly diagnosed glioblastoma.
E.5.2 Secondary end point(s)
The first secondary endpoint is overall survival (OS)[color=red][/color] compared between patients randomized to placebo who received DCVax-L treatment following disease recurrence, and control patients from comparable, contemporaneous clinical trials, in patients with recurrent GBM.
GLTU
Thanks flipper.
In any case, it seems that the best thing to do
is cause a mutation to Mesenchymal.
This could be done with a short course of chemotherapy.
But hopefully a method will be found in a different way to do this.
Then the immune system also remains intact.
GLTU
Thanks pgsd :)
Great news hmuney.
Thanks for sharing.
GLTU
Flipper,
Without chemo would of course be fantastic.
Very interesting analyse and discussion.
But don't we need recurrence because of the (possible) transition to Mesenchymal?
Thanks in advance for an answer.
GLTU
Thank you meirluc.
Great research.
GLTU
Great post Roman516.
Thanks,
GLTU
Thank you StonkMaster for sharing.
GLTU
Thanks pgsd.
For all of them.
GLTU
As usual Lykiri, Thank you !
GLTU
Depends on the publication newman.
TLD (PR) should be almost the same time as publication.
And this must be before ASCO so that they can make all the details known and explain.
imo
GLTU
Thank you Viking, great post.
I think the cabal (F...Stein ao) have lost a lot of their gunpowder.
It is obvious what argument they have used (PFS) to convince the world of their "right". If this is their main weapon then the cake will run out quickly.
Soon this will of course be brushed aside after publication and ASCO.
Their eventual new arguments then only become weaker and nothing more than blowing in the wind. They have lost their spice and Cofer has become wiser again.
GLTAL
Thanks for sharing RRH.
Very interesting.
GLTU
hoffmann,
I have 100% confidence in LP
She once said in an ASM: "maybe they (the dark shorts) will fall into a trap".
And I believe that will happen.
We will see.
GLTU
No problem with a MC of $100 billion.
My guess : It's a trap !
LP is a cunning fox
GLTU
Thanks for your post pgsd.
Totally agree.
My preference is really a collaboration with fi a BP that takes a 20% interest for a large amount of dollars and will do a lot of work in exploiting our product (L and D) in the entire world .
This would guarantee us the future appreciation of the pps, looking at the potential of NWBO. I would sell a small amount of stock to make life a little more pleasant and let the rest 'run'.
My children and grandchildren will later on think back to this adventure and its result . Granddad who was 7 1/2 years telling the NWBO story when he was not on his computer (lol).
The world will look a lot better if these expectations come true.
L , Direct and then all solid tumors and maybe other diseases that will make a big improvement with our vaccine. A victory for humanity.
This is my convinced opinion.
Best to you.
Thanks for all the good things you do overhere pgsd.
GLTU
Great post Chiugray.
Thanks.
GLTU
Thanks flexroy, for sharing.
GLTU
Nice one CherryTree !
Thanks and GLTU.
Great post sentiment, thank you.
Strange that Ex hasn't responded yet.
To say perhaps : thank you sentiment for the information.
:):)
Best to you.
basparks,
We think the same.
Like you, i was also investing in anavex years ago and before that I also had to deal with him with my prior investments .
That guy is a horrible criminal and I also agree with you that he is a tool for competitors or indeed parties who want to bankrupt NWBO in order to steal the tech cheaply or to bury it.
Best to you.
Thank you ae kusterer.
Well done and keep up the good work you do.
Best.
Thanks flipper.
All interesting.
Still learning from your knowledge.
GLTU