Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
Perspective as we go unrecognized by the "wall"
I'd also like to add that the author is using old FDA trial design. The FDA will introduce the new procedures soon enough and should benefit baby bio nicely.
With that reasoning, why keep Fragile X, Infantile Spasms, Angelmans up there too?
Fun times ahead, plus the possibility of BIIB taking a-273 over for MS. How interesting does my post about "angel numbers" sound NOW. hahaha
post 120131
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=134604196
Would they reveal the pk/pd data the same time that a presentation titled:
"Clinical Pharmacokinetics and Pharmacodynamics Characterization of ANAVEX™2-73 for Designing a Phase 2/3 Study in Mild-to-Moderate Alzheimer’s Disease" will be given?
Missling did say that when its available, it'll be released. Does/Doesn't mean it has to be at a conference.
http://www.ctad-alzheimer.com/files/files/Late%20breaking%20posters%20theme%202_0.pdf
I just so happened to sell some other stocks at a loss to get more Avxl when it was 3.95 this morning.
Turning out to be a good idea
Who is this Meg woman that you speak of? She obviously don't read the board, for if she did, she would have gotten a link with many a trials that are trying to crack Alz. Just shows how much Axon was being pumped by everyone including the news.
Don't for get to mention what the bottom of slide 27 says too.
"The following data represents all evaluable patients"
No cherry picking in that graph.
This is why a few on the board think we are on hold until the 21 CCA master protocol is put in place. New rules, New ways of thinking.
Trials get ran quicker and if they are safe and effective, off to market and continued data collection continues.
Speaking of continued data collection.
Anyone notice the announcement today?
FDA selects participants for new digital health software precertification pilot program
https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm577480.htm
That's 2 totally different companies. EVERYONE here knew Axon had little chance.
Now on to the next plaque trial and readout.
Not a secret hidden meaning, but a close before the ball starts to roll. Like was the wed start and end day it? or end with a 750 purchase?
Missling ended his pre-purchase plan right before news last time. So maybe it's what bas is thinking this go round too.
Purchase of 375 continues, no news yet.
Real question. If Axon Alz trial doesn't impress, what does that mean for a-273. Not pps wise but how it's looked upon.
Can't forget a good CEO. One that would test their lead candidate for failure sooner rather then later is a great step. *check*
How many ceos would take that challenge? Or is that twisting the truth a little, and he misled us again?
Anyone happen to know a reliable site that if I bought a couple shares, they would send the actual shares to me?
I'm more of a put it in a frame and show it off type of guy.
Like that first $1 a restaurant made.
Too funny, that's not correct either. More like 32 patients took the drug, one lucky golfer, pianist, grandparent......
HUGE difference between generalizing "hundreds" and the exact number that YOU even know.
Not at all. It's only down the drain if I sell. I don't plan to sell, so nothing to worry about.
If data released is bad, then and only then will I re-access the investment. Until then, sit back and watch the story unfold.
$4 and I'm dumping other investments to make room for a "shift in priorities".
That's true for a day trader. For a long though, it's the drug and could care less about the daily pps.
Tell em about how Anavex was a print shop before too. Oh.... and how the company many years ago bought ads to pump the stock, BEFORE Missling was even there.
All old news that got disputed on the board if one were to take the time and did some DD.
Inovio, you know how it was back when you were the positive outlook investor and hated when naysayers would post all disgruntled? Let's not be that naysayer, although this co. Truly deserves it.
On the other hand, if it wasn't for the failure of the CEO, I would have never found AVXL. It surely is one of the best risk/reward ratios in a very long long time.
Check them out as they seem to be brewing something and could pop at any moment. Look at their instys slowly increasing each quarter.
The possibility of helping Alz, Rett, MS, Epilepsy, Parkinson's sufferers.
Hopefully its the type of company you wanted when you invested in RXII.
Do some DD and hope to see you over on the other board.
Much much more?
The bar is low already for Alz. No other pharma could even help them longer than the SOC, which is about 2 months.
If the 25 patients decline has slowed, they are already on the "radar"
Whip gets it
I can see high 3's. I'm thinking one more attack before the news starts flowing.
Its why I have a small slush fund if it dips below $4. If not, I have enough to be happy.
Come on brich, I clearly put a heading of don't take it seriously. Have fun during these slow days.
Eventually we will pick up and start rolling up hill.
Try this idea as an out there one. Its all just for play so please don’t take it seriously
Most copied from here: https://www.sunsigns.org
First Purchase this go round was 750:
Spontaneity is the pioneer meaning of number 750. This is the openness to evolution. It is the ability to be radical. You are a very rigid person. Everything you do is calculated. It is difficult for you to make decisions quickly. You put a lot of thought to your answers. You have met this new person in a business trip. They are inviting you back to their country for a function. All this can be a metaphor and you may be going through a similar situation.
Olga says that Angel Number 750 is associated with the letters M, N, B, S, H, J, and E. Olga suggests that to find out what the Angel Number 750 is about, try to make words of those letters.
We get MS
Then theres the 375:
The angel numbers would like to assure you that they will be by your side at all times. Angel number 375 is a sign for you to understand that the efforts you have been making in the recent times to build for yourself and family a great future will soon come to be successful. Hold on.
Olga says that Angel Number 375 is associated with the letters I, U, F, D, N, B, and L. Olga suggests that to find out what the Angel Number 375 is about, try to make words of those letters.
We Get BI (First 375) IB(Second 375)
Or we get fud then fud again. = )
5250 makes for a nice reading for that number if Missling happens to have purchased till the end of next week.
Anyway, I drank a little to much this evening.
Goodnight
Again, please don't take this seriously as Im just having it on record just in case something does come up of it.
Dr. Missling, our Angel communicating with numbers. = )
Quick facts I found when I found a link talking about BIIB Alz drug
By 2050, one new case of Alzheimer's is expected to develop every 33 seconds, according to the report.
Goldman projects that sales of Aducanumab could reach $12 billion
So, change a few words and we get the following:
Anavex lead drug for Alzheimers is projected to reach sales of at least $12 BILLION dollars
I think its about name recognition. Investors know the BP names and to have your small bio next to big names "looks" nice.
Anavex? not known so much....yet!!
He will never be one of them. For if he was, we would have been sold for pennies. That's guaranteed no matter what the naysayers say.
Buying out a pharma after a p1 for $3B was a easy enough example.
Right...... as an amateur CEO would have lost the company a while ago.
I'll wait till the end of the year, how's that timeframe? By then, I'm sure a trial or two would have started, which then starts the timer for data readout 3 months later for some indications.
I even speculate the reasons as to why only 750 then 375 shares are being purchased. That's another post though. ????
And a year or two ago, wasn't this the topic of discussions for a while. Why even have placebo when there was enough data to provide a historical placebo. It's cruel to give participants false hope.
Then the naysayers insisted that unless its blinded, it doesn't hold much weight.
Now look at 21cca and how they blew that theory out of the water.
Positive Data will move the company up or down, and until there is factual evidence that a-273 and the drugs beyond that is a failure, I'll continue to hold. All else, is just games the market play. Like that link to some "insider" source about a top secret meeting between Anavex and PFE.
I wouldn't say we all would rather have news, because I could care less WHEN he is ready to take the next step forward. Could be tomorrow, next week, or next month. Bottom line is when he feels like the company is ready for its next step forward, only then will he move forward.
You do understand that if a-273 even halts the decline, we are a threat to ALL BP, right?
You don't think they are waiting for the same data that we are?
Same hint that a-273 just might be the SOC?
Another week of Missling purchasing.
375 Shares
http://secfilings.nasdaq.com/filingFrameset.asp?FilingID=12276604&RcvdDate=9/11/2017&CoName=ANAVEX%20LIFE%20SCIENCES%20CORP.&FormType=4&View=html
Sorry if it was posted earlier
Firstly, thank you for bringing to our attention the link you provided. It's information about the co that the investor decides if it means anything or not. It's not anyone on the board that makes the final decision on what to do with said investment. Each takes what speculation is given and decides what to do with it. It's why I enjoy reading MOST posts on the board.
Then there's the 1's and 2's. ; )
Do they even count as a credible source?
I know I would count them as anything BUT credible.
Of course they are. Give one reason why they wouldn't be?
What other drug restores homeostasis?(According to whats been shared with us from PR and/or conferences)
Better yet, I'll just post a quick copy and paste on symptoms of MS and see in what areas a-273 could help according to what has been put out from the p2a/b clinical trial so far.
Pain areas: in the back or eyes
Pain circumstances: can occur in the back due to head nod or with eye movement
Whole body: fatigue, dizziness, heat intolerance, poor balance, vertigo, or weakness
Sensory: pins and needles, abnormality of taste, reduced sensation of touch, or uncomfortable tingling and burning
Urinary: excessive urination at night, leaking of urine, persistent urge to urinate, or urinary retention
Visual: blurred vision, double vision, or vision loss
Sexual: erectile dysfunction or sexual dysfunction
Mood: anxiety or mood swings
Speech: slurred speech or impaired voice
Also common: constipation, depression, difficulty swallowing, difficulty thinking and understanding, flare, headache, heavy legs, limping, numbness of face, rapid involuntary eye movement, sleep deprivation, tongue numbness, or difficulty raising the foot
Are we done with an "important" person leaving the co and needing a PR for it?
I'm expecting help in the form of 21cca.
With that, it's anyone's guess as to how government would or would not help a possible drug that has the potential to keep Medicare and Medicaid alive vs below water.
See my previous post explaining exactly this as to why I wouldn't take a buyout. Microsoft style is the way to the riches if this plays out the way MOST of us here are hoping.
None. Better to be surprised than setting yourself up for disappointment.
There wasn't one of him joining back in August of 2016, so why would there be one of him leaving? He worked there for 1 year 2 months, almost the same month BIIB started testing a-273, and we are making a big deal as if he was there from day 1 because.....?
He could have gotten a better compensation package for all we know.
It's about the drug anyway, no matter who comes and goes along the way.