did the career thing long enough.
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Thank you, Couch..
most long-timers here have been aware that major manipulative games have likely been played around PPHM for years, as with many (most?) small-cap Bios. do you have access to enough numbers to see that going on here, now?
if so, does this tend to be just trading strategy, or is it an accumulation thing on the heels of the kind of PR we had yesterday relative to this stock/industry?
CP
i appreciate your numerous, lengthy, and educational posts, which truly oveflow at times, with important points most here generally aren't equipped to handle at the levels you refer to.
it would be sweet if the scenarios you suggest prove to explain the road PPHM will be eventually able to survive in time.
it's time for you to throw your legions a few tidbits about your background. if your response is as shrouded as your handle, you should be able to do that without blowing your cover or agenda.
Krak...
i've been around here a long time... a lot longer than my 'born' date.
i'm one of around 25 long-timers who i would bet have a love/hate relationship with pphm like mine, but my investing world doesn't only revolve around it. that's why i pay some attention to those who live and breathe this stuff 24/7 like those whose names can't be spoken...i've found they know what they're talking about more than so-called 'analysts' who pay more attention to EPS vs. S&P than science/potential.
PPHM is my largest single holding outside of ETFs, funds, etc. and has been for 13 years now (with the exception of about a week in September 2012!)
my 'flip flop' s are not about my style of investing...they're only reactions about impatience when i see so many other outfits in our segment and stage having share price success we don't have.
most of those have significant institutional ownership, and the market experts here will mostly say that's a requirement before you can go to the moon, since there's something big in it for those institutions when they make the price run. that's why it's no surprise that we can't sustain upward spikes!!!!!!!
will this management team make it without wall street support? we shall see.
was 1.54 close enough???!!!
i am long, with a substantial position. doesn't mean i'm not aware of what pphm is up against, whether it's from bashers or it's own issues/obstacles.
we all want it to be successful, both for scientific as well as financial reasons.
it just makes me crazy when people here are stunned when it can't hold gains.. the reasons are apparent and everywhere as of today.
that could change forever with one sweet PR.
and DD and AF were wrong about the value of fast track? only PC has said he hopes pphm fails...DD and AF have not.
i don't know why so many folks here discount the points they make. if you listen, you could learn something.
pphm's finances are still not squared away long term (they're correct), the science still has not been monetized(they're correct) , gains in share price are always short-lived (they're correct)... traders are still the only ones who make money while the wait continues for the science to prove out (they're correct)...if it ever does (hopefully, they're incorrect about that)
messengers are constantly shot here..
now THIS is the PPHM i remember! down 18% in 24 hours!
the shout-out in Daily Finance might be helping. it noted the original p2 results and downplayed the trouble...
eyebuy said "Unless we get another PR on financing, that gap is going to fill"
absolutely, completely agree. PPHM needs another PR (a meaningful one) for follow-through or it bleeds back to same old-same old, and soon.
the skeptics are largely right when they say fast track doesn't mean much, although it's certainly different for each company and candidate.
in PPHM's case, it's about somebody other than Tustin and their paid supporters in the medical world giving bavi some indication of efficacy.
PPHM has been trying to gain credibility back for a decade. this is just a step along the way...possibly a big one, and maybe it will help draw institutional support. almost no biotechs spike without that.
it could mean the FDA sees signs of efficacy, could it not?
sure wish we could drop 1 more PR bomb before we bleed back to $1.50...
understood...
thanks, grad...
pphm's trial wasn't preclinical... screwed up, yes...but preclinical, no
anybody ever tell you you're a bit stubborn?
whether fast track is worth anything or not, has the fda ever granted it to a drug which they don't believe has shown efficacy in earlier trials?
can anyone answer that question rather than one i didn't ask?
i said i realize that fast track does not mean it will be successful. my question is whether the or not fda has given fast track to drugs that only indicated safety rather than evidence of efficacy.
if PPHM's data was so questionable, why would they be given fast track?
could it be that the fda was shown convincing evidence that the p2 was intentionally tampered with in order to attempt to invalidate it?
for those who have repeatedly said that showing good safety data is enough to have the fda allow p3 to go ahead....are there any cases where 'safety-only' drugs have been granted fast track?
i'm not suggesting that fast track means bavituximab will ever make it, but this designation seems to say that the fda doesn't view the drug the way many here do.
best news of the day is that AF published a Street article with a trashing of pphm just as the PR came out.
OOPSY!!!!!
i believe it was dr brekken who referred to improving response rate by 2-300%, or something to that effect...
love AH
you said "I wonder what kind of investor sees themselves in an adversarial relationship with the management of a company they bought into. If you don't trust them, surely you shouldn't hold their stock. Even more so for a struggling micro like Peregrine. "
i can be a long-term shareholder and still ask whether Board members are taking advantage of their positions to the detriment of stockholders like us.
it's very fair to ask if execs got bonuses for announcing 2 centers recruiting out of 100 planned on essentially the last day of the year in order to qualify them for the milestone payments....
Thanks, Dew... I hope others will post some favorites as well...
Are the heart pump stocks like HTWR, THOR, and SSH out of bounds on this board? Interesting stuff going on there these days...
Dew... sorry..i worded my post poorly...what follows may not be much better!
what i'm wondering is..what stocks intrigue the sharp people on this board to the extent that they feel some significant upward moves could be right around the corner as they become better known for their progress, whether real or imagined? i'm not specifically looking for price targets...I'm looking for Biotech "Values".
what are current opinions of PPS upside on Dew's 'survey' winners over the next several months, with or without being acquired?
it's one thing to be widely acknowledged as a target, having moved up already, but it's more fun to become identified as a target before everybody gets on the train.
who might be on that list, other than PPHM? (relax...that was a joke)
that was a personal attack.
how about skipping the riddles and make your point clearly.
numerous cumulative trials show bavi to have stunningly few AEs. that is well known... i wouldn't read too much in to the few bleeding events in the P2 in attributing them to pphm's drug.
frankly, i'm thrilled and amazed that it's hanging at this level after another potential $100 million dilution in the absence of a healthy infusion from a partner...
yet people here assume the know the FDA was critical...
this stock has been a trader's dream for over 10 years. it's dangerous now.
for cryin' out loud, DD...
if you were a patient, would you take crutcher's advice or your doctor's? there are long-term survivors who have taken pphm's stuff, just like there are for other drugs which haven't made it through the process yet. what do you say to them?
you know, the trial centers aren't walmarts...at least, not all of them :)
i know you side with pc cuz he shares your deep doubts about pphm, but that's a hell of a leap.
jeez
from the october archives.... why is yesterday a surprise?
honestabe13 Friday, 10/25/13 09:56:55 AM
Re: None
Post # of 153417
don't now why this action is surprising anybody. there hasn't been a reason for this stock to go anywhere but down for the last 6 months. frankly, i'm amazed that it's hung around the 1.30s this long; lack of partnering news could easily have this under 1.10 at any time over anticipated dilution.
here we are, about to enter phase I trials, while 15-20 years of research has generated no deals worth mentioning.
how about a positive surprise, Tustin?
great news on the shorts!
forgot Thurly..
england
one of the things i enjoy most about the regulars here is that you folks are from all over the place... keeps things in perspective sometimes...
hope you all have a great holiday...
please feel free to add to the list below...and don't be shy about throwing in more specific geographic stuff than states or countries...
maine
massachusetts
connecticut
new york
california
illinois
kentucky (DUH)
canada
belgium
austria
puerto rico
new jersey
florida
rhode island
Merry Christmas, carboat!
has to be a big move, and be sustained, before there will be much chatter.
triple witching is every 3rd friday in march, june, september, and december...
"Investopedia explains 'Triple Witching'
The final trading hour for that Friday is the hour known as triple witching. The markets are quite volatile in this final hour, as traders quickly offset their option/futures orders before the closing bell. If you are a long-term investor, triple witching will have a minimal impact on you."
triple witching. many, many stocks had crazy volume at the close.
market loves the article, eh?
why is pphm so invisible?
if the science behind the article is so striking, why isn't it in a U.S.-based high-profile journal?
it's because it "could result in robust and long-lasting anti-tumor immunity that significantly improves clinical outcomes.", not because "it does result in..."
still pre-clinical. need loan/partnership to move pps.