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BioHedge Why would you want to take Otezla with it's numerous side effects and is not as effective as Prurisol and it takes more time to work?
I personally think the Biologics are the ones in BIG trouble if Prurisol comes close to hitting the PASI 90 range...I mean BIG trouble...
agree and even more with a partnership.
It's all about potential!
That's what BID means...eom
George the P dosages are 150mg and 200mg BID.
Prurisol will take sales not only from Otezla put EVERY biologic out there!
Relentless4ever Somebody requested a 6 week data look see.
Early bird catches the worm:)
January/Feb. word will start to leak out that patients are seeing OUTSTANDING results and the stock price will reflect it. Placebo effect is very very low in the mod.sev category so we will know for sure it is Prurisol doing it's thing!
MEGA Blockbuster INDEED!!!!
Quicker trials.. Quicker Approval...More Revenue...BIGGER deal with BP.
Prurisol over B-ABSSSI is a NO brainer.
Can you image if these 2B results show clear or almost clear skin in 6-8 weeks?
OMG!!!!!!
From the P Phase2 trial.
"Some of these patients even experienced a 3-point reduction in their IGA score, going from “moderate” to “clear.” This suggests Prurisol may be more effective in treating moderate to severe psoriasis patients to a greater degree than those patients who exhibit less severe symptoms. In moderate to severe psoriasis studies, the placebo response also tends to be lower."
Clear(IGA 0) is a PASI90 score. A small % of Biologics achieve PASI90 with multiple and some life threatening side effects. Prurisol is achieving PASI90 with 200mg. The 300mg and 400mg dosage is gonna ROCK the Psoriasis market!
BP has to be going crazy when they see what Cellceutix has in their advanced pipeline!
MONSTER deal(s) are near...VERY near!
I've said it before and I'll say it again.
A BIDDING war will happen for Prurisol..
200mg dosage providing the same results as Otezla at the same point in a trial is EXTREMELY positive in my view. It will be EXTREMELY EXTREMELY EXTREMELY positive after the 2b trial or at the interim.
Otezla is toast and many of those NASTY NASTY Biologics.
A bidding war for Prurisol after the 6 week data is revealed.
pre market $1.42 x $1.50.....
come on baby come to momma.
$4 by end of 2017?
Do you have any idea what's going on with Cellceutix?
Let me clue you in.
OM p2 trial completed 2017
P p2b trial completed 2017
Up p2 trial completed 2017
k OC p2a trial completed 2017
Not to mention a GUARANTEED partnership on Prurisol.
You need to add a zero to the right.
$1.42 close SSSSWEEEET!
I believe 6-8 weeks was the biggest jump in efficacy in phase2 of Prurisol.
Can you image if P can hit " clear or Almost clear" in that 6-8 week timeframe with 300-400mg dosage?
NOTHING on the market comes close to that!
I can hear the commercial now.
"Prurisol given orally can clear you Psoriasis in as little as 8 weeks"
DERN!!!!!!
They make sure the Placebo group gets a dirty needle:)
uh No thank you..................
Guselkumab was generally well-tolerated by the trial participants, the study notes. Side effects occurred in 65 percent of patients taking guselkumab, as well as half of the patients in the placebo group. The most common side effect was infection. Other side effects included gastrointestinal or musculoskeletal disorders, poison, injury or procedural complications.
JnJ already has Stelara. Yup another injectable with a GAZILLION side effects. Prurisol the PILL is badly needed!
I read some where that Cohort B will start in December so an update on cohort A results within 44 days.
1.27 x 1.50 at the open....games people play
because based on the mouse studies they figured 200mg was enough.
Abacavir was safe at 600mg.
Thoughts on why only 27 patients in 400mg group for P trial?
lol..Now I get it..
P Patent good until 2032.
So approval in 2018ish....
What is 13-14 years of patent protection for a multi Billion $ drug worth to BP?
The various attributes of Prurisol are that it is a new chemical entity with strong intellectual property and patent protection via a composition of matter patent good through the early 2030s and a unique advantage of being able to use the reference drug abacavir or ZIAGEN is the trademark name for it, as a reference drug to accelerate our development program. This utilizes advantages of a 505(b)(2) type approach where the long-term safety of the drug can be referenced to abacavir because abacavir is a major metabolite of Prurisol.
Call this clean huh..?
BigKahuna Wednesday, 11/16/16 11:52:00 AM
Re: cabel post# 164031
Post #
164036
of 164042 Go
The company stated several times that side effects are minor other than allergic reactions for Prurisol but specifically we can only look to Ziagen which has some fairly common side effects:
Group 1 - fever;
Group 2 - rash;
Group 3 - nausea, vomiting, diarrhea, stomach pain;
Group 4 - general ill feeling, extreme tiredness, body aches
But, the above occur at significantly higher doses double to triple that of Prurisol. Then looking at Otezla:
Otezla side effects
Medical Editor: John P. Cunha, DO, FACOEP
Last reviewed on RxList 11/11/2016
Otezla (apremilast) is a phosphodiesterase 4 (PDE4) inhibitor used to treat adult patients with active psoriatic arthritis. Common side effects of Otezla include:
diarrhea,
headache,
nausea,
upper respiratory tract infection,
vomiting,
runny or stuffy nose,
abdominal pain,
fatigue,
indigestion,
decreased appetite,
insomnia,
back pain,
frequent bowel movements,
depression, (severe)
bronchitis,
tooth abscess, and
sinus headache.
WebMD: Rare side effects
Rare side effects of Otezla Starter:
Having Thoughts of Suicide (Severe)
hypersensitivity drug reaction (Severe)
Suicidal (Severe)
more like BioHazzards!
Leo holds the upper hand with P.
BP is dying to get their hands on Psoriasis drugs, especially a Pill.
It's WHEN not IF.
Everything will change WHEN a partnership is announced.
We anticipate starting the ovarian cancer Phase 2a trial which is going to be focused on establishing the mechanism of action of our drug Kevetrin later this quarter or at the latest probably early first quarter of 2017.
R
Wonder what our price will look like after a $750mm - $1B deal with royalties is signed for P?
I know 1 thing I can probably take the 25 posters I have on Ignore off cause they won't EVER be back!!!
2017 is gonna be UNREAL for Cellceutix and we shareholders....UNREAL!!!
Daubers you meant above $5 now...right?
it will be a bidding war!!!
GO PRURISGOLD!
Struggling?...Now that's funny...
So Cellceutix lied when they said Presenting...shame on them!
down 10%...Laughable
seriously?
rr50 this one has dupes. He wasn't lying.
http://finance.yahoo.com/news/cellceutix-provides-corporate-reports-q1-213000463.html
$1.40 close? WooHoo ain't seen that in a while...