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These are all guesses and IMO…
So if 200 responders combined 40 high dose and 160 30 Mg average 3.6 point increase ( mental decline)..
Let’s say 80% responded..so 160 of 200
Scored the overall 2.25 average score increase..this means 40 dosed patients
Would have to increase by 10 points twice the placebo historical decline in ad..
So.. we did not see and 80% response rate in non high dosed nor in high dosed non responders..
Thinking with as much as TGD focused on high dosage equaling common denominator the 40 high dose did respond ..
And the 160 30 Mg patients saw some slowing of symptoms over and above placebo..
Guessing of the 200 dosed low responders
They still average better than placebo..but since placebo 4.5 drop.. guessing
the 120 high dosed super responders really lift up the numbers..
The OLE of PDD and AD should show the titration to higher dosage
the dosing at night and biological evidence of higher S1r expression over time will make over 80% of all participants super duper responders..
We will get a feel for these numbers from PDD OLE
80% of 160 is around
120 super responders who will be
At their baseline or improved..
Since the average of 320 dosed is a 2.25 increase..this means 200 (40 high dose and 160 30 Mg) averaged 3.6..
So the 30mg and non super high dose..
Still score better than placebo..by about 1 point after 48 weeks!
Awesome..
I keep in mind this is average.. so in the high dose non responder and 30 Mg you still have great responders but.. you also have some non responders dragging down the average.. the place where you aren’t going to see these number dragged down IMO is the High Dosage.. Super Super are going to be miraculous
I can only get summary
Theft by inflation..
Super responders from their original baseline will be over 80%..
Well over 100
The only reason people won’t take this drug is because they can’t afford it
From a capitalist point of view..
We could not ask for a greater population to effect..
Travel
Sports
Bucket lists!
Presents for grandchildren
Freeing up caregivers to produce and follow their dreams instead of grey hair sitting..
So many positives coming our way
10% of worldwide population will benefit from Blarcamesine!
10 billion
1 billion helped
Everyday…oops I mean every night!
You got the 10% right..
just the wrong population pool!
Anecdotal bennies..
Sleep
Conversation
Reading
Enjoying movies
Golf
Driving
Seeing better
More energy
The Friday before Christmas
Wonder if anyone recognizes these guys?
SECURITIES AND EXCHANGE COMMISSION,
Civil Action No. 22-CV-____ (___) v. JURY TRIAL DEMANDED
EDWARD CONSTANTIN, a/k/a “MrZackMorris,” a/k/a “Edward Constantinescu,”
PERRY MATLOCK, a/k/a “PJ Matlock,” THOMAS COOPERMAN, a/k/a “Tommy Coops,” GARY DEEL, a/k/a “Mystic Mac,”
MITCHELL HENNESSEY, a/k/a “Hugh Henne,” STEFAN HRVATIN, a/k/a “LadeBackk,” DANIEL KNIGHT, a/k/a “Deity of Dips,” and JOHN RYBARCYZK, a/k/a “Ultra Calls,” a/k/a “The Stock Sniper,”
Defendants.
COMP
Notes in sec filing
It’s the most wonderful time of the year
You don’t have to wait..
We have loved it for 7 years
Traditional rare-disease patient advocacy has slowed the pace of therapeutic development through privileged silos and the bottlenecks of territorial 501(c)3 non-profit groups. However, RAM’s novel community-based platforms and the rare360 programme12 are the first-ever tools available to the drug development continuum that take a wider approach.
Anavex not first company to run into..
If we cure it .. we don’t have a job .. crowd
OLE for AD and RSS and PDD has hundreds of patients on high dosage for years..
These fudsters are running out of time..
They know
for whom the bell will toll!
It tolls for rhee troll
What kettilbjorn said..
Fierce biotech should be
forced to keep all communications for future fraud investigation
So in layman’s terms..
Blarcamesine patients will
See the Light!
Every email text from anyone at fierce should be deposed for fraud
You are terrible human beings Fierce biotech!
Just terrible
Loves us very much!!
Haha
I was doing so well!!!!
So you don’t like the way they are about make you rich?
Ok
I get it
Last post for day..
Happy Chanukah and Merry Christmas everyone!
Our Creator lives us very much
So I am about to run out of posts so will take a second here..
First as an early dementia sufferer and lover of human life.. I take great affront to those who root against anavex and actively try to undermine their mission.
They want to kill us and they suck.
I don’t know how else to tell you how horrible these people are..
And they have children! They have parents! Yet they try to profit from our suffering and root for our death.
Second.. when you complain about Missling getting something right..
We have no , none, zero zilch nada of how difficult running multiple clinical trials for multiple maladies during an effing plandemic has been! How many things has Missling gotten right for a small biopharma that others would have failed so miserably? I can’t even begin to explain how easy failure is.. but if you don’t know.. me telling you won’t help..
Third.. we have succeeded at every turn except the financial
Markets refuse to accept and reward our success.. ok.. take advantage of their ignorance. We have the OLE data
THD and three other prominent Research docs have said we met endpoints..
Get rich
So just to be clear..
We are the mushrooms
You pay TGD a lot of money
to try and get this right..
We are longs and we are along for the ride
A fool?
Really? So we will see how big a fool
TGD is.. he hasn’t sold a single share..
We shall see who the fool is..
The MB poster of boring repute or the long term Avxl holder who never sells..
Won’t be long now
I know plex
Timber..
it’s not just that..
They have OLE data for years of patients on Maximim Titrated dosage..
They don’t just like our latest clinical data saying that it MEEtS ENDPOINTS…
They KNOW the OLE data( have had access to data through entire OLE PDD, AD and RSS..
So when THEY say we met Endpoints
What THEY mean is
Blarcamesine is saving lives..
And they KNOW IT
Plex I know you have been patient
I know you have been very supportive..
I understand that he wicked level of frustration.. I suffer it as well.
We must find our strength and share the good news of Blarcamesine anywhere and everywhere.. pretend like you don’t own a single share and don’t care about the $$$.
Share the good news of Blarcamesine.
It works! Far and wide.. epoch news
Bobby kennedy childrens health defense fund the gateway pundit… Breitbart..
Anywhere where freedom still breathes ..
Share the good news
Hey Plex and all other unhappy longs..
Cassava has a good Pharma and is going to release data on 200 patient ole by end of year.. maybe you should move on over there? Let us buy even cheaper Avxl stock..
Honestly .. the longs here are like having the French defend your flank
TGD has heralded a Greek man’s invention through a Corporate shell by raising around $10,000,000to try and make it fail..
Subsequent we have worldwide patents on at least two different drugs I believe for hundreds of treatments..
including epilepsy and schizophrenia and depression.. maybe even sleep..
And our company is now showing a value 50 times greater than when TGD started.
TGD has never sold a share of anavex stock for profit.. the contention on Thai board by fellow longs is ..
TGD purposefully mismanaging good news clinical data release to confuse the market and to engorge
Short sellers so that TGD’s reward options stay cheap?
Just wanted to make sure I understood just how insanely frustrated some investors are.. that they would accuse our CEO of being such a weak knees trollop
That he would purposefully delay acces to Blarcamesine for little girls suffering Rett syndrome so that TGd could cash in on cheap options? WTH is wrong with some people?
Short distorters have fed on anavex because big Pharma desires it! No more!
No Less! And because FB group of AVXL longs helps them by selling momentum every effing time!
So look in the mirror longs as to why our stock price sucks.. it’s not TGD..
It is YOU
Is it possible TGDtrying to put ducks in row for Voucher is causing delay?
Plex
Dr Missling and three other prominent Docs of high standing have said we met primary and secondary endpoints..
That really should be all the market needs..
That short sellers and their wicked lying mouthpieces obfuscate and attack every single awesome clinical
Data point is uncontrollable..
That short hedge funds have deeper pockets than longs is uncontrollable..
That biopharma investing is rigged..
Is without contention..
The first time 7 years ago( phase 2a data release) where we proved safe effecious and our MC got destroyed for it..
We all knew this would be a battle of good vs evil.. evil doesn’t surrender because
you are good! Evil must be crushed by the Light!
It’s coming.. hold on.. It’s coming
So we can buy the stock at $8 too?
If everyone would stop buying this stock until MrN sold or lost Caesar share..
Mr’ the ceo would be forced to act legitimately.. until then.. the dilution will continue unabated
My son .. a shareholder..
Said I guess we should just buy more..
When you don’t invest in winning or losing..stocks are simple
And the FUD will be flying the entire time
Dr M said HIGH DOSAGE common denominator..
Then he he said we passed primary and secondary endpoints..
So the high dosage group is going to be over 80% super duper
I think you are way low ..
Trying to lower expectations?
High dose will be over 80%!
Perhaps as high 90%.. that by itself is
144!
Plus some 30mg are going to be better off as it is early AD..
30%? 48!
I see almost 200 super reaponders!
Anyone remember these guys ?
Synaptogenix Announces Topline Results from NIH-Sponsored Phase 2 Clinical Trial of Bryostatin-1 for Advanced Alzheimer's Disease
We on same page Batman