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So IMO my feeling tells me that they are going to finally make announcements of trials being started with AstraZeneca. Most likely multiple trials. Since their drug is now approved for at least one indication. Hopefully this comes with some cash or some kind of merger since astrazeneca may also be looking for avid to their benefit also. Just my crazy thought and take. Anyone have thoughts or a say so on this?
IMO I am gonna call on this manipulation and scare tactics to get everyone and anyone to start selling. Expecially throwing up that ask of over 300 thousand shares at .20 hmmmm IMO that ask is someone trying to get more shares in his bank cheaper. Got a bidder for 50 thousand at .19 why not just sell them if they know something. Again all IMO.
I personally imo could not agree with you any more. Just maybe because it's my birthday too. Get ready and rise eltp. IMO looking at some really good days ahead. Happy birthday to me and you. May elite be the best birthday gift we receive.
So can you explain is this like what Bavi would help with?
Not sure if it's a good thing or a bad thing? Where did everyone go?
they are also presenting embargoed information at 1pm correct? Which means there could be a mid afternoon pr regarding it which could be the pusher?
Volume looks low in the whole market today.
So I found this or should I say came across this. Things going on and to be brought up and presented at asco. So how do I take this? How do I view this? Expecially with embargoed information. I don't know if any yet FDA approved test that are out there? Does anyone know of any test FDA approved out there? This really caught my eye or should I say caught both of my eyes and opened my mind and brains a bit. Can it be pphm???? Can it be??? I sure hope so. I sure dream so. All imo chime in guys what do you think? Straight from the article on things to expect from asco in April. Improving the Lives of Cancer Survivors
Despite these challenges, the ASCO report found there is much to be optimistic about in improving the lives of cancer survivors, including treatment advances; increased funding for the Beau Biden Cancer Moonshot Initiative and the National Institutes of Health Precision Medicine Initiative; and the approval of 16 new and expanded use cancer therapies by the U.S. Food and Drug Administration (FDA), along with two first-ever cancer diagnostic tests: a liquid biopsy test for lung cancer mutations and a sequencing test to identify patients with advanced ovarian cancer eligible for a specific cancer treatment.
Pgg. Thanks for answering me I appreciate it. So is their a way to find myself or other individual retail holders? Or just institutions?? Thanks again in advance
Quick question pgg? How do you check something like that? Thanks in advance ..
I dream of a pcyc type move. God I dream. My lord would life be diffrent. Expecially to know I was a part of a drug or test that can save many lives. Rewarding in both ways. Good luck to all.
So maybe it's just the circle of life but does black rock investments own 5 percent or more of AstraZeneca who also owns a decent amount so far of our little pphm? And then maybe biopharm could help on this one cause I only checked Steve worsley linked in profile for the first time. Did it always say under his accomplishments at pphm that he negotiated and finalized a agreement with a 2nd one? • Negotiated/finalized clinical agreement w/Astra Zeneca/MedImmune for NSCLC studies involving the combination of bavituximab with PD-L1 inhibitor: Durvalumab. Followed by 2nd contract 3 months later for add’l clinical combination studies. When in fact as far as we know it's under evaluation???? So maybe biopharm is this new on his profile?? Could this all mean that something is a brewing and hopefully after the emborgoed information we can finally here some good news?? Just and all IMO.
I'm just going to throw this out there. Wasn't AstraZeneca/medimune once a over 5 percent holder in xenocor? The company ronin capital was also invested in? Puzzle piece? Solving the puzzle? Who knows? IMO. I'd like to by a vowel to solve the puzzle. Is like by more shares before the puzzle is solved. IMO just curious ???
A patients wish. My wish. Taken from AstraZeneca tweet. Could pphm have that test. For the sake of human kindness and progress I sure hope so. IMO Tweet
Conversation
AstraZeneca? @AstraZeneca
“Some way to detect it early”: an #ovariancancer survivor’s wish for others #SGOMtg #DDRdays
Embedded
4:15 PM · Mar 12, 2017
23 RETWEETS
22 LIKES. She writes also "If there is one thing I could do right now for ovarian cancer ? It would be a screening test. It would be some way to detect it early. We all want a cure, but if we can help woman detect it earlier it would be much better."
From AstraZeneca's website
More than 80% of AstraZeneca’s clinical pipeline now follows a personalised healthcare approach and in the next eight years, around 50 of our planned drug launches will require a linked diagnostic test. Working with external partners who specialise in developing these diagnostics is critical to our continued success in this area.
Partnering is really important in the field of personalised healthcare. AstraZeneca’s search of biomarkers linked to drug response starts right from the outset of a drugs’ development journey and continues all the way to market. By collaborating with companies that have the best technologies and expertise in diagnostic science, we are able to generate the highest-quality companion diagnostic tools, which healthcare professionals can use to make treatment decisions. So could my AstraZeneca puzzle piece still stand imo.
MEDIA
LIKES
AstraZeneca's Tweets
21h
AstraZeneca? @AstraZeneca
Ready for the updates from #SGOMtg starting tomorrow? We’ll be updating on our progress in #ovariancancer (link: http://bit.ly/2naukIY) bit.ly/2naukIY
this was a tweet sent out by AstraZeneca so also just in my opinion who says peregrine has to pr the news if any? Didn't AstraZeneca pr the collaboration news last time? Jmo could be what do you call it a puzzle piece..
Just my thought my prediction my own opinion. Astra Zeneca is no longer knocking on the door they are finally going to open the door. Astra Zeneca has and been working hard on biomarkers. They have completely relied on biomarkers to advance and promote their pipelines over the last few years. First they know of bavituximab and have Trust in it to collaborate then comes along exsomes and a proof of concept kit. So now basically they have a complete platform to work with ps targeting. So in my own opinion I have and ofcourse hope AstraZeneca is finally ready and going to lay a lot more on the table and start the ball rolling. Wishing everyone the best in their investment. The science has been their and that's what kept me sane. Looking at the pps day in and day out will kill some cause money at the end of the day is all some care about and why some are here. However you have some guys here who from the bottom of their heart give you some really good detailed information. Just to be shot down and ignored cause once again some guys on this board just see money want money now. They get in they get out they buy and sell every chance they get not caring if they themselves even bring the sp down. So with enough said on what I think. I will say hopefully the time and the shedding of light is not too far away as the pps can fluctuate but the science is the science and that could never go away. Again good luck every single true dedicated long. A lot of people don't like Mondays but this could be the one Monday you would never mind. IMO
Some one please help for my own information. What is the date we have to be over 1 dollar to. E complaint?
What I fine even more interesting included in all the job postings at zero is the fact the mr. Hutchins leaves at the peak of all this???????? Very interesting for sure.
Fly high don't look back peregrine. Our regular readers will know that Peregrine Pharmaceuticals (NASDAQ:PPHM) is one of the companies we have long highlighted as one that we see as being undervalued, and by proxy, due a revaluation. On a number of occasions over the last few months, we’ve discussed our thoughts on the stock, and the most recent of these occasions came on February 12, as part of this piece.
We had two sides to our argument.
The first, and the longer term thesis, is rooted in the unique positioning of the company as both a development stage biotechnology entity and, concurrently, a successful contract manufacturing company. The latter arm, the CM arm, generates revenues that Peregrine is able to use as development capital, and this removes a large portion of the risk generally associated with an investment in an early stage biotechnology entity – namely, the potential for dilution driven by the need to issue equity to raise capital.
That’s the bull driver we’ve been pushing for a while, but alongside this thesis, our second argument (and the one we focused on in our recent coverage) was rooted in a near term catalyst. Specifically, the company is developing a cancer diagnostics platform, and earlier this month, reported that it had successfully completed proof of concept study for said trial. For those that missed the coverage, and by way of a brief introduction, it’s rooted in what are called exosomes. They are bits of cells that break off from primary cancer cells, and after breaking off, are free to roam about a patient’s body in the bloodstream. They express something called phosphatidylserine (PS), and Peregrine has developed a technology that is able to detect (and measure) the presence of PS in a patient’s blood.
The concept, then, is relatively straightforward. The more PS, the more advanced the cancer, and that’s what Peregrine’s tech is set up to measure.
So where does this play in to a near term bias?
We think the company, now it has proof of concept data in hand, can start pitching for a big name partnership. The data relates to ovarian cancer, which for those not familiar with the oncology space, is a global unmet need across pretty much all aspects of its treatment – diagnosis, first lie therapy, maintenance, etc.
A host of big name pharmas are pushing ovarian cancer assets through various stages of the development pathway – AstraZeneca plc (ADR)(NYSE:AZN), Clovis Oncology Inc(NASDAQ:CLVS), TESARO Inc(NASDAQ:TSRO) – as are some smaller, but equally viable, names – TapImmune Inc (NASDAQ:TPIV), Oncomed Pharmaceuticals Inc (NASDAQ:OMED). With a diagnostics platform that has proven benefit in an ovarian cancer indication, Peregrine could easily attract one or more of these names into a collaboration deal, and with any deal would likely come an upfront cash injection.
So we covered this last time, why are we highlighting the company again so soon?
Well, Peregrine just started to run, and it doesn’t look like it’s going to slow down anytime soon. The company traded for circa $0.3 a share at the beginning of the month. By the end of last week, this had risen to $0.55 – an 85% run. Most of this run came last week, subsequent to us highlighting the company and its partnership potential post-OC proof of concept.
To put it simply, we think that markets are finally latching on to this company’s longer term potential, and that it took a shorter term catalyst to get things moving – a spark, if you will. Now that the fire is lit, however, we don’t see it slowing down. Sure, we may see a correction, as traders who picked up an earlier exposure pull profits off the table. For us, however, these pullbacks are an opportunity to pick up an exposure at a discount ahead of a return to the overarching upside momentum.
Is this similar to what peregrine has or diffrent? Can someone please let me know the difference thanks PORTLAND, Ore. & CAMBRIDGE, Mass. & DETROIT–(BUSINESS WIRE)–#drugdiscovery–Asterand Bioscience, the leader in high quality, well-characterized
human tissue and human tissue-based research solutions supporting drug
discovery and development, announced today a partnership with
MolecularMD to combine MolecularMD’s expertise as a provider of
molecular diagnostics products and services with Asterand Bio’s drug
target and candidate validation capabilities. MolecularMD is a molecular
diagnostics company that develops custom clinical trial assays as well
as companion diagnostic products, supporting clinical trial services and
commercialization of targeted cancer therapies. The partnership creates
an end-to-end workflow for biopharma clients and strengthens the
companies’ current offerings in assay development & validation, while
creating a global footprint for the efficient delivery of clinical trial
sample analyses.
“For over 20 years, Asterand Bioscience’s experienced scientists have
worked collaboratively with clients to expedite the highest likelihood
for clinical success by providing a variety of pre-clinical
research services,” said John Canepa, Chief Financial Officer/Chief
Operations Officer. “This agreement brings together MolecularMD’s proven
track record in clinical assay development and companion diagnostics
with Asterand Bio’s human tissue procurement, characterization and
research services to provide a comprehensive approach to meet the needs
of pharmaceutical, biotechnology and diagnostic companies from
validation of biomarkers and targets to assay development, through
regulatory and clinical trials.”
“MolecularMD is uniquely suited to assist biopharma clients with our
clinical trial and regulatory expertise,” said Dan Snyder,
President/Chief Executive Officer, MolecularMD. “I’m excited that
Asterand Bio and MolecularMD have joined forces to provide these unique
advantages which will help our broad client base accelerate their
pipeline decisions and dramatically improve the efficiency of the
clinical trial and commercialization workflow.”
Asterand Bio and MolecularMD will both attend Molecular Med Tri-Con
2017, Feb 19-24 at the Moscone North Convention Center, San Francisco,
CA, a meeting bringing together over 3,500 drug discovery and
development professionals. More information about the partnership can be
found at Asterand Bio’s booth #626. Asterand Bio and MolecularMD will
both attend the AACR 2017 meeting, April 1-5 at the Walter E. Washington
Convention Center in Washington DC, a meeting that highlights the
highest level of cancer science and medicine from institutions all over
the world. More information about the partnership can be found at
Asterand Bio’s booth #1340 and MolecularMD’s booth #3423.
About Asterand Bioscience
Asterand Bioscience is the leading global provider of high quality,
well-characterized human tissue and human tissue-based research
solutions to drug discovery scientists. Our mission is to provide
human-based solutions to accelerate the identification and validation of
drug targets and enhance the selection of drug candidates with increased
likelihood of clinical success. From our offices in Detroit, MI and
Royston, U.K. our employees are focused on providing services and
products to accelerate drug discovery research from target
identification through to compound evaluation and drug safety.
About MolecularMD
MolecularMD Corporation develops and commercializes specialty molecular
diagnostics for oncology applications. Tests are designed to allow
appropriate selection, monitoring and management of patients treated
with molecularly-targeted cancer therapies. MolecularMD integrates
gold-standard and innovative platform technologies with clinical assay
design, validation and centralized testing to accelerate all phases of
clinical development, including FDA approval and commercialization of in
vitro companion diagnostic tests for novel anticancer agents.
Contacts
Dear management and the bod I totally agree. My honest feeling and opinion is up until this point in time you Guys truly and honestly have not at all been deserving of a bonus of any sought. I will currently speak for myself. Your salaries are very nice let alone a bonus. So put your money where your mouth is right now and by a decent amount of shares to show us and the investment community the faith you have in the company as a whole. On paper right now you guys have cost me my life. Yes a investment is a risk however it seems like your silence and ability truly has got us nowhere fast. Open up and buy some shares on the open market and I mean enough to show the investors we are in it with you. Thank you and merry merry Christmas to all
So can someone help me out with this question? If a buyout lets just say. Then your saying it would be for only 16.5 cents the closing price of Friday? Is that what I am understanding? Thanks.
Can someone please help me with the letter(draft) of what I should send and the addresses to send it to? Honestly these people have really ruined my life and I will do anything I can possible now at this point. Thank you all in advance.
Honestly if someone gets it started and finds away I am more then willing to pony up. I have had more then enough. This is total bs. I'm tired of this crap. Tired. Let alone the loss. Enough now is really enough.
Please some honest feed back without yanking and chains. Could this stock possibly be a 2 dollar per share stock? If so when do you think this is possible? Thank you in advance for some honest feed back.
Is anyone else having a problem trying to get on to the investors page of peregrine?
Count me in. I am so fed up and tired and down way too much. I get sick saying how much. They really are big clowns at this point. I'm sorry. I don't mind losing but this is beyond belief. No concern at all for us. Let's wake up and charge at them.
Totally agree. Maybe we should start opening a door with our voices for a change. Maybe numerous letters in numbers gets a response. Something has to be dealt with. Our money is just disaspearing into managements pockets. That's my concern. Period
Honestly with a closed mouth and too tight of a ship. 2.25 yes 2.25 and it's all yours. Or all of any big pharma.
Agree agree agree. I say lets do it. I am all for something. I have been too patient and on paper down way too much with no answers no guidance no light offered. On paper I am one of them down large figures. Listen honestly I never considered getting filthy rich but I also never visioned being poor. Listen I don't want to huff and puff and blow the house down. I just want to know what the house is made of and how we plan to keep it standing. I'm ready as a concerned shareholder.
Thank you for answering north
I just had a quick question maybe someone can help me answer? If the company was offered and sold for 1 billion how much per share would that be? 4 dollars? Thanks
Please I would love to post this article anyone can help me biopharm maybe? Thanks
Great article published in nature.com I don't know how to post it sorry so bad. Ps targeting very well mentioned on February 26th.
Am i insane? Everytime they push us beat us knock us down.(or at least try) I go scrounging around looking at every checking account every savings account for ways to buy buy buy. Scare tactics is a great show. But when it comes to pphm and my investment. I want to be on the right side. Not the left outside. Just also a thank you to everyone who works so hard with great information. Peregrine now has enough patients and now I just need to have patience. Good luck to all my fellow long time investors and truly much success and continued extended health and life to anyone suffering. My prayers always.
Looks like peregrine updates a lot of trials as enrollment complete. Or did I miss something and this was done awhile ago?
Pj dropping pphm answer I got is its not good nor bad. Just very costly and it was all financial. Trying to get a little more info on Monday when my friend from pj returns.
Missing? Does any one else notice and realize that certain names have been missing in action for the past week? That alone may be a good sign. Just saying. All the best always to my fellow true and long pphm investors. Cheers guys it's a coming.
Thank you good and plenty for the first to offer. Once we take off I will make arrangements for a gathering. It would be great for everyone to attend and help and should they not be able to attend their generosity will always be appreciated and going to a great cause. One we all have our hearts and hopes in already.
Thomas