During the conference call the main point they made was that is in the FDA letter, the FDA wanted them to show they fixed symptoms - pain, bleeding etc. Provectus designed the study to CURE cancer, NOT treat pain, so didn't have much data on side of symptoms. Common sense would say curing cancer is better, but they couldn't convince the FDA of that because the FDA refuses to accept any "drug" that actually CURES cancer. Which is why on Dr. Carl June's therapy may actually come to fruition - because it is gene therapy to cure cancers. IMO and from my years of biotech industry experience, this is typical of the big business drug industry. Don't cure the disease, find a drug to treat it and make it feel better, so u can sell it for life and make more $. I don't think there was any wrong doing, incompetence or negligible action on the part of Provectus.