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LOL we used to like Stupp when he toed the company line LOL
what??? that table is NONSENSE
hmmmm ok I will take a look at the video,,, oooops! no I wont LOL
cute answer, but if thee are not a sponsor or collaborator there surely MUST be an agreement that entitles NWBO to use that data, Let;s see that agreement
also, note this study uses ATL-dc, not dccrap. also nwbo is not a sponsor or collaborator. hmmmmmm
that study will be interesting but not conclusive as it is a small 40 pat phase 1 study.
that is theoretical; as we really do not understand efficacy yet given the mistakes made in teh conduct of the study
but while connecting dots we must remember that se cannot connect a dot that dccap is soc. It aint LOL LOL
actually the slide is raising a question, how can we accelerate these therapies. It say nothing about already having these therapies or denying such
lol what would cause that damage . Oh of course he failed to be a rabid fan of dccrap
Or maybe he is completely instep when the oncology community . By that I mean practicing oncologists not the get rich quick investors in these pos companies
the attacks on Dr Stupp are hysterically funny and demonstrate a new level of desperation. He has been frequently mentioned as a guru crying out for new therapies. He has now written criticizing the study methodology and he has demonstrated that he is not a consumer of the POWERS koolaid and so now he is old, feeble, cant write and likely somewhat senile. LOL this show gets better and better by the day LOL
that is confounded compounded bullshit
Pazdur and Stupp are the same age
LOL I am sure Dr Stupp will be relieved to hear that his opinion is valid LOL LOL
wow, what are those details that make it doubtful?
Al is shall we say kindly biased in favor of a particular therapy. Not very charitable lol lol
So dccrap is not Soc thanks
LOL so now Stupp is is endorsing DCCrap??? Nah LOL
LOL vexatious nonsense, so they use Avastin. hmmmmmm must be SOC
lol one doctor but what about the hundreds of others that treat rgbm . What did they use ???? Lol
Prove it
Their attitude is “it’s just paper” dilution doesn’t concern mgmt
True I have been to foot doctors for foot problems. But I don’t think I would be going if I had brain cancer
Seems he did thx
Yes he was is a brain surgeon so what? Are we supposed to bow down ?
Thanks Hygro. Good to have a real credible source like you
No not referring to that greedy hack
He is very credible, one of the few
Probably the foot doctor looked at his performance an was embarrassed lol
Confounded bullshit lol
breathtakingly nonsensical
what??? ok what I think i get out if this is one comes before two comes before three. Gee I didnt know that
wow, that is wonderful. perhaps you could explain the power calculations used in this study, That would put this in perspective. Must be hundreds in this study????
a few, possible, but not relevant as that is NOT a primary endpoint
Primary Outcome Measures :
Cell cycle-related signature [ Time Frame: Up to 6 years ]
Expansion of T cell receptor (TCR) clones [ Time Frame: Up to 6 years ]
Two-sample T-test with Bonferroni adjustment will be used to compare the increase number of expanded TCR clones after dendritic cell (DC) vaccination with PD-1 blockade in Group A versus (vs) DC vaccination with a placebo in Group B.
Incidence of adverse events (AEs) [ Time Frame: Up to 30 days post treatment ]
Adverse events will be graded according to Common Terminology Criteria for Adverse Events (CTCAE) version 4.0. All patients who receive any amount of pembrolizumab/placebo or ATL-DC vaccination will be evaluable for toxicity, serious adverse events (SAEs), and events of clinical interest (ECIs).
Seems explanations are in order:
What is a Phase 1 clinical trial?
Phase 1 clinical studies or clinical trials are focused on the safety aspect of the new drug, rather than its efficacy in treating a disease. Phase 1 trials typically involve 20 to 100 people, a combination of healthy volunteers and patients or people with the condition.
the Phase One Foundation, supports early cancer research
leadership???? she might be a fine banker or lawyer but she had never developed or brought a new drug to the market
It I’d highly unlikely this p1 would qualify as a registration trial . Remember also it is a combo trial that makes analysis and interpretation more complicated.