Could you expound on this point a bit?

Lol... We must be close!

Ridiculous...

Just like the DCVax trial was never expected to end?

Hear! Hear!

I don't think it will take 2.5 years for FDA approval, but I am interested why you think so. How long are you estimating it will take NWBO to write/submit the BLA (assuming it isn't done already)? What is your estimate of time FDA will require to review it and make approval decision (assuming NWBO hasn't been working with FDA-- i.e. rolling review-- all along)? Just curious.

No it was an official email sent from Northwest Biotherapeutics <dinnes@nwbio.com>.

AF's cabal will continue their deeds even after approval. The won't stop.

Thx Captain. That sounds reasonable. With DCVax approval and the combo patent, good times are ahead.

"practically impossible" was what everyone thought about cancer vaccines... but yet here we are.

Or maybe it's because LP refuse to start negotiations with BP from a position of weakness... and with a 68 cent pps.

With approval, DCVAX as SOC, Direct and the combo patent, BP will be at the table. They won't have a choice.

You cannot deny LP Completed the first multi-continent, statistically significant trial in 20/30 years for rGBM and nGBM! No matter what you say, this fact cannot be denied and this accomplishment alone is worthy of celebration... is it not?

At your convenience, can you elaborate on this a bit more?

Well, I could be... I am not God... but I don't think I was "Bamboo-Z-Led". In fact, I am so convinced (based on data, patents, oncologists/journals, etc) that I am all-in--- I even invested 25% of my retirement in NWBO.

We will soon know!

Good question. That was my question when I first learned of the DCVax + PD-L1 combo patent. I Never clearly understood how NWBO could get a patent to combine their drug with another already patented drug... and still don't.

For me the patent allows one company to create the combo product, let's say DCVax-Plus (DCVax-L + a PD-L1). Since most patients (68%) had tumor-cell PD-L1 expression(see article here), DCVax-Plus would be more effective (and could replace DCVax-L). Additionally, DCVax-Plus could be priced less, due to increased demand, than buying both drugs separately.

So, if NWBO were to acquire a PD-L1 drug or merge with a company who has a PD-L1 patent or get bought out by a company with a PD-L1 patent (like Merck), your question would be moot because only one company has DCVax-Plus and it wouldn't make sense for a doctor, in this case to prescribe DCVax (without PD-L1) to combine it with someone else's PD-L1. Pricing would render it a non issue... assuming a doctor could/would do it.

Also, Merck's $17 billion PD-L1 patent will be over in 5/6 years. NWBO's combo patent imo literally forces Merck to buy/merge/partner with NWBO, resulting in a renewed and expanded patent with a potential of unlimited revenues from the DCVax platform that will become SOC for all tumor-based cancers! Furthermore, Merck has to make sure that another BP doesn't beat them to a deal (as every BP who earns significant revenue from a Pd-L1/PD-1 drug has to be looking at NWBO and it's combo). LP is getting the data, approval, patents ready for a bidding war or maybe she's partnering with all BPs. Either way, this is huuuuuge!!!!

Of course, keep in mine that I am not a patent or any other lawyer. I know shit about patents. I am not even a very knowledgeable investor. My opinion sounds very logical and reasonable to me but may be insane nonsense... what do I know.

I have no doubt we invested in a prize. The data is out. Once approval is given and combo patent is awarded.... can't wait.

He won't respond... there's nothing he can say... no defense. He'll just move on to rehash another baseless attack.

I agree.

Why would a journal wait on/for approval.

WTF do you mean they couldn't finish a single trial?! What company creates a desperately needed drug for a fatal disease without pursuing patent protections!

What a dumb@zz comment.

The way I see it, Merck must immediately buy (or partner with) NWBO before their $17 billion wonder drug is made worthless (by NWBO merely using someone else's). This Combo patent is NWBO's coup d'etat on cancer AND on Big Pharma's control over it's treatment... but what do i know.

Hear! Hear!

Exactly right, Bright Boy...

BS. Trial finish.

I Agree...

lol.

lol.

I am not breaking out the Boones Farm (lol) or partying yet... but I am excited because (1) the trial is done (preliminary results were released), (2) manufacturing is in place & scalable and (3) The combo-patent will force BP to engage with NWBO via partnership or buyout.

Everyone who has held NWBO throughout all of the bs that has occurred over the years, when we had little evidence DCVAX worked (while Phase5, AF and others constantly talked trash), should be excited, imo.

This is a real-life David vs Goliath story of which I am privileged to be part.

lol.

lol.

That says it all! Thanks for the reminder.

Hear! Hear!

I have been invested in NWBO since about 2013. I have NEVER been more excited about my investment prospects as I am now.

Thanks for your comments. Excellent post!

That may be the case but wtf can be automated after DCVAX has been made?
(not directed at you).

Perhaps DI can clarify.

I hope he has been put on notice... but don't think he can help himself.

Agreed...

I hope I didn't jump the gun here... let me review.

I watched the Brexit debates and have been saying it ever since.

When NWBO rockets to the stratosphere, I'll stop using "Hear! Hear!" and use "Ordaah!" (i.e. Order!) to calm long-time longs down, lol.

I love watching British debates.

The application has been submitted but the license will not be implemented/received until AFTER approval. This is my assumption... could be wrong.

My focus was that approval is very near!