Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
falconer, if you would, could you tell us what the blarcasemine rodent studies concluded in regard to sleep.
BB
[Your advice might just as well have been get another mortgage and load up more cause this one is dead cert.}
This board is excellent fodder for straw man arguments.
BB
[The composition and method Patent covers ANAVEX 3-71 (formerly AF710B) for treating Alzheimer's disease (AD), type 2 diabetes and insulin resistance.]
Thanks.
I don't seem to remember any discussion on this board about type 2 diabetes and insulin resistance.
Seems huge.
BB
Xena, trying to find patent info for A3-71.
I looked in [Compiled: IP protection] to no avail.
Help?
BB
Isn't 21 the fastest way to results/approval?
BB
[ Back around the turn of the millennium I distinctly recall hearing any number of key opinion leaders tell authoritatively that Amazon.com was destined for failure. No profit margins. Big debt. Altogether a flawed and hopeless business model. Stay away. Don’t be a fool. ]
Considering the foolishness that abounded during the dot-com era that was excellent advice and it's a shame there wasn't more of it.
BB
So you're saying they used the orange flavor to mask the bitter taste?
Just kidding.
BB
Uh, let's just get 273 APPROVED first.
BB
I still struggle with the enormity of what is being proposed on this board.
While composing this post in my mind, I realized A2-73 would not be the first compound the government decided to distribute en masse.
That would be fluoride and it was introduced with a whimper not a bang.
Since the poor have worse health than the rich, I would think the governments of the world would use some of the saved medical dollars and create mass distribution networks.
It would be the height of stupidity for only the insured to have access.
Or maybe I'm all wet.
BB
[ Well, I’ve scrutinized the phenomenal data yielded by Anavex 3-71. In murines, even better then Anavex 2-73. Also, all of the other sigma-1 receptor agonists in the Anavex pipeline.]
On this snowy morning in Wisconsin I would love to here all you know about
the other sigma-1 receptor agonists in the Anavex pipeline.
BB
What that article tells me is Hampel has zero experience in his new job and was probably hired for his name and reputation.
I certainly wouldn't blame him for wanting to cash in on his years of work but I'd bet he struggles.
BB
History would suggest liposuction .
BB
When I'm not busy being mad at you I very much appreciate the work you do.
BB
I'll take that bet.
Much of the selling in '17 & '18 could and probably was attributable to tax loss selling.
A common practice is to repurchase in January which would have been at 2.10 and under.
See you on the other side.
BB
Doc, There's been quite a bit of talk lately about what a veritable goldmine all the extension data is.
Is your opinion, how much weight would regulatory authorities put on such data?
BB
Is it possible the orange flavored drink the Rett trial participants are given is what Juan Ponce de León sought?
BB
"A picture is worth a thousand words".
And sometimes a thousand words paint a picture...
"This is an important development as the patients who have completed the main study, ANAVEX2-73-AD-004, are consistently expressing the wish to gain ongoing access to this investigational therapy," says A/Professor Stephen Macfarlane, FRANZCP, Head of Clinical Services at the Dementia Centre, HammondCare and Principal Investigator for both studies".
We keep hearing of eagerness to continue with A2-73.
BB
Several times in the past Falconer predicted that in this time frame some of the mothers would no longer be able to contain themselves and would joyously extol the virtues of A2-73.
I respectfully disagreed, saying the fear of having their child asked to leave the trial due to their loose lips would win out.
This video would be an interesting work-around to that problem.
BB
I've made an assumption with no real evidence.
I always assumed if we got approved here or there for Rett we would have sufficient money to fund all the rest of our trials and thereby cease diluting.
Do you (or anyone else) think this is true?
BB
Does the chart on page 3 mean we are done with ph2 and in ph3 in Alzheimer's?
BB
If someone did do a written transcript it would be quite helpful.
BB
Is it even running?
The last AZ news I remember was "we're screening".
BB
For what it's worth, Rhett is the #167 ranked male name by popularity.
BB
Twenty(ish) years ago there was an NFL running back named Errict Rhett whose star shone bright for a year or three.
I'm sure his name appeared in the mass media hundreds of times.
If you've ever read the book Thinking fast and slow" by Daniel Kahneman you'll recall that's how the human brain works.
We quickly scan our memories for similar instances and equate them to the present subject at hand.
Just a guess but I originally spelled it with a "h" until Falconer called us all out.
I was heavy into fantasy football at the time.
BB
On an entirely different subject, you've mentioned in the past that the veterinary use aspect for A2-73 could be huge.
Looking at the pipeline nothing animal related jumps out at me.
What am I missing?
BB
But these were adults.
Do we know anything about the BMI of adult Rett sufferers?
BB
I find it helpful to look at AVXL as a value stock.
https://www.safalniveshak.com/why-value-investing-works/?utm_source=Daily+AR&utm_campaign=cb78c65a98-RSS_EMAIL_CAMPAIGN&utm_medium=email&utm_term=0_c08a59015d-cb78c65a98-140329101
BB
What really excites me (as others have referenced) is the 5 mg. dose.
What might the optimal dose(say 15 mg.) do to a young girl.
I'm also very curious who decided upon 5 mg.
BB
I've pondered on my weekend walks what the world might be like 10 years from now if A2-73 plays out the way we dream of.
Will it be the new one-a-day vitamin and will the world population become healthier ?
Since we'll be healthier and hopefully more clear-headed will we demand that the governments 'round the world direct the massive health care savings toward the greater good?
Or will our worst come out and we'll realize we can lead even more self abusive lifestyles and just not pay so severe a price?
BB
I would hope any sort of a deal would provide enough upfront money to halt the diluting so I'm not sure I'm with you here.
BB
I'll be curious to see how the stock analysts value the company.
How do you value something that becomes the SOC for multiple diseases?
And then throw in A3-71 and it's pipeline pals.
I'm anticipating a game of analyst leapfrog.
BB
As Falconer has been alluding for some time now, how could it not be as good?
BB
Was wondering if the Aussies saw similar results and that's why they ok'd juveniles?
BB
[Also, I'm surprised about the turn around time for data analysis.]
That was my first thought.
My second was "wouldn't it be cool if that's how it's going to be going forward".
My third thought was "wow".
BB
A fortnight perhaps.
BB
I think they're just preparing for all possible contingencies.
If a partner steps up with a good offer after positive P2 results I think we'll take it. But I don't think we'll wait very long.
BB
For what it's worth...
"It never was my thinking that made the big money for me. It always was my sitting. Got that? My sitting tight!”
-Jesse Livermore
BB
I'd be downright pleasant to be around if the share price was $9.35.
https://www.americanbankingnews.com/2019/09/01/anavex-life-sciences-corp-nasdaqavxl-receives-average-recommendation-of-buy-from-analysts.html
BB
Does this article speak to the potential of A-1066?
https://www.frontiersin.org/articles/10.3389/fphar.2019.00222/full
BB
Makes you wonder what a successful A2-73 would be worth.
https://www.reuters.com/article/us-bristol-myers-divestiture-amgen/amgen-to-buy-celgenes-psoriasis-drug-otezla-for-13-4-billion-in-cash-idUSKCN1VG102
BB