Look at a chart. Any chart. Any indicator. It's going back up at some point.

This is a bit off.

Xenograft simply means inserting cells or tissue from one species into another.

You can't grow a human tumor in a mouse because the mouse's immune system will attack the human cells.

These mice were made to be immunodeficient so that the xenograft could grow and they could determine the drug's effects.

These mice didn't have a fully functional immune system. So not like humans. Other information in his post is spot on.

2014? 2016? Older than dirt?

What are you even talking about? How fast do you think drugs go from bench to bedside? 3 months?

It takes decades. By all accounts this is moving quickly.

This drug has huge upsides but also unique challenges

1. tiny patient population that has ovarian cancer (half population gone since it doesn't occur in men, you probably didn't know that. and just a very rare cancer in women)

2. GHS wanted to reap the most benefit so they used Redman to launch this from a private start up rather than just sell the patents or drug to a larger company with huge pharm infrastructure. Now they could have done that. But GHS and the investors would not benefit near as much. Hence why you can buy this for nickels and dimes and not 175 a share for some huge established pharma that just rolls this drug into it's portfolio.

My favorite part of this is how Redman has to mention in the filings how "volatile" the company's (AEPP) stock is...

He has to make all those disclosers because often people in the OTC pink world don't act rationally. They in fact behave against their own best interests. It's shocking sometimes. Now this happens at every level of the market. But that's why hedge funds and index funds exist on major markets. They remove the much of the irrational human error.

Hence why flying is safer than driving. Less humans involved. Just highly trained pilots. Not 23 year olds hyped up on energy drinks. Wait... sounds like OTC penny stocks doesn't it...

Hmm....

Anyone--> look at any indicator and make a technical argument about why the this stock will stay anywhere under .1

I'll wait...

This all sounds good. Who did you talk to?

The only real question is how high will it bounce.

Just loaded more.

Out of no where in the next 3 weeks this stock will gain 200-500% just watch.

CHEAPIES!

This reminds me of the trough down to .016 right before the huge run and new base at .09-.11

Ah how irrational some traders are Sell! Sell right before the huge jump!

Classic.


Check back to this in 2 weeks.

still here. holding fast.

ain't selling.

I always look for scams to invest in thanks! I prefer scams with investors like the state of texas and large us hospital systems. Wow this one has both! What a deal!

No. Just no.

What are you even talking about? Did I ever say that? Nope.

I said:

"The way a phase 1 trial is designed is to do small groups (usually of 3) till you get to 12-18 patients, slowly raising the dose to monitor for adverse effects in humans... "

The estimated enrollment is 18

https://clinicaltrials.gov/ct2/show/NCT02534922

No one thinks 3 patients is enough.

Nope, wrong again. 20-100 is just a standard number. This isn't a cholesterol drug.

This is an orphan drug. Only 200k people get ovarian cancer per year....out of 335,000,000....

The requirements for ALL phases of the drug development are lower. Look it up. Look on other clinical trial websites.

Here's an example

https://clinicaltrials.gov/ct2/show/NCT02253264

This is for the blockbuster drug, Rituximab, trade name Retuxan. For a new application in MS.

Do some research! You need to!

https://www.fda.gov/ForIndustry/DevelopingProductsforRareDiseasesConditions/default.htm

You don't understand how the stock market works. It's ok.

The uptick in volume just indicates the stock is about to move.

like i said yesterday... volume picking up. volume preceeds price increase

Preliminary data from the first dosing group (the low dose) of this trial suggest Prolanta is safe with some evidence of efficacy in a patient population that is difficult to treat.



What do you think is going to happen when the raise the dose... Once they drop the news that the next dose is even more effective....and the next...

Preclincal models have shown effectiveness, enough for investors to drop $20,000,000 to get it to trials...


The way a phase 1 trial is designed is to do small groups (usually of 3) till you get to 12-18 patients, slowly raising the dose to monitor for adverse effects in humans...

If the LOWEST dose has shown some efficacy... I think we are in business big time assume no freak adverse effects. Watch news about the effectiveness to drop after name change. Thats a nice little easter egg on the website...

volume quietly picks up...

Did anyone notice this new line on the website...


The Company has a US FDA-cleared IND to commence human testing of Prolanta™ in our first indication, the treatment of ovarian cancer. This clinical trial began in 2016. Preliminary data from the first dosing group (the low dose) of this trial suggest Prolanta is safe with some evidence of efficacy in a patient population that is difficult to treat.


Once Redman doses the next group then drops the efficacy information (meaning not only is the drug safe but it helped slow down/ kill some of the cancer) that will be huge.

You know they have tricks up their sleeve once this name is changed. They need to raise another 30 million to get this thing thru phase II. The only way to do that is get to a market cap in the hundreds of millions and sell into it.

I've been here since the Nigel Bosworth days.

#nigelbutthurtbosworth

Incorrect. Hey what happened? Weren't we supposed to be at .09 according to you?

The updates are picking up in frequency.... watchers be warned...

WEBPAGE UPDATES LETS GO!


https://www.oncolixbio.com/news-and-events.html


AEPP Announces Proposed Name Change to Oncolix, Inc.
HOUSTON, TX, August 22, 2017 -- AEPP, a Houston-based biotechnology company focused on gynecological cancers, today announced it intends to change its name to Oncolix, Inc. The new name is expected to be effective after the mailing of notice to its shareholders in September. The Company also intends to adopt a new stock symbol at that time. AEPP recently acquired all of the outstanding securities of Oncolix, Inc. in a reverse merger completed on August 3, 2017.

“We are very excited about the name change as it more accurately reflects our focus as an emerging biopharmaceutical company with a clinical-stage asset”, said Michael Redman, CEO of AEPP. “This is the latest in a series of steps to re-position AEPP as a biopharmaceutical company with an exciting product portfolio.”

As Oncolix, the company expects to accelerate this transformation through the execution of key priorities and anticipated milestones, including:
Strengthening of the board of directors and
Building the clinical/scientific advisory board
Submission of Prolanta™ for Orphan Designation in the European Union
Building of drug pipeline beyond Prolanta
Uplisting to a national securities exchange
Clinical results relating to Prolanta

Hey let's get this ibox cleaned up. Time to get ready for traffic.

This morning's filing was huge. Perhaps the most important one yet. I have been buying since this was at .04 and have continued to follow and load. IMO it would be wise to load.

Name change coming very soon!

Well well well. Turns out the longs were right as per ususal. GO AEPP!

SOON TO BE ONCOLIX--> ONCO ONCL ONCX or something ha!

Correct!

You act like that's a bad thing. More chances to average down. The pop will come and it'll ride.

I am starting to worry guys....


That I won't get a drop to load more before news hits!

Unfortunately I can only see the first bit. I was looking at another when I shared the link. More positive news by the looks of it.

https://www.bizjournals.com/houston/news/2017/08/13/money-makers-houston-life-science-co-completes.html?ana=RSS%26s%3Darticle_search&utm_source=dlvr.it&utm_medium=twitter

Not the best picture of MR. Ha. But a good article.

You don't understand stocks or rational thought. It's ok! You are a learner.

oncolix bio home page has been updated. ticker added. wont be long before that ticker changes!

Big volume this morning!

What makes that interesting? Any insights? Thank you.

You need to consider this for clinical trials.

1.It takes a long time to find people and enroll them.

2. They are making the drug "as they go" which slows enrollment. They have noted they need to make more drug. That's fine. It costs them like 300K to make it for just a few patients. It wouldn't be wise to dose 18 people at once. What if the dose was wrong? What if there were side effects? What if you needed to alter the delivery mechanism?

3. Three patients done so far is perfectly fine. That being said they need to get going if they are going to finish this in 2018.

FORM 3 for GHS and Texas technology trust fund out.

10Q next then ticker change then $

It shocks me people are too stupid to buy this stock. The movements yesterday were on like 100 share buys and one decent sell. This is so thinly traded it's embarrassing. Redman and them noted erractic shareholder behavior of AEPP in the 8k.

Just buy it and hold. Get a hobby do something with your life. Ignore people posting on some message board. This is bigger than that. Yes it might flop. That's typical for a drug company. But that's only going to be known after trial data is released, which could send it sky high. Either case it's months away.