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It is a puzzlement... or not! ROTFLMAO
You said,
RBL continues with extremely positive results, company secures more financing and the negative comments explode. Must be some kind of correlation. Not sure exactly what it is or why. LOL GO IPIX
The sky is falling! The sky is falling! Again and again... LOL!
That Horseshoe Crab omen is apparently very strong...
From TheHound in response to A Novel’s post... https://www.smithsonianmag.com/smart-news/race-coronavirus-vaccine-runs-horseshoe-crab-blood-180975048/
From A Novel,
LOL, Last week while walking the beach, I walk up on a rather LARGE HORSESHOE CRAB. Definitely a rare find for me, as that was a first in my lifetime and I am 45 years young. I did a little research and discovered that a horseshoe crab's blood is worth approximately $60,000 a gallon.... Boys and Girls.... I think we have an astronomical find with Brilacidin... GLTYA! Green Skies AHEAD!
You said,
I think it's not smart (the gentle version) to think that a facility owned by a German, or any foreign, Corporation would be directed by a US President under a law focused on "the domestic industrial base"*** to manufacture any particular product. Check that...make it "could", not "would". Some guys will TRY anything
The "bully pulpit" argument MIGHT work but it would still require an agreement that would probably involve the distribution of product to non-US territory.
Evonik is HUGE. ... They would almost certainly do it for the usual reason if they could be guaranteed payment.
Is that (THE cure) what you're offering? I thought it was 97% or something like that. In a petri dish.
DPA powers are pretty broad and the on-site management at those 30 locations in the US might be influenced by the threat of prison. Also does any international company really want to be seen obstructing production of THE cure for this worldwide pandemic. Trump may not be popular in Germany but the optics for an international corporation under those circumstances would be really poor.
From Wiki,
The Act contains three major sections. The first authorizes the president to require businesses to accept and prioritize contracts for materials deemed necessary for national defense, regardless of a loss incurred on business. The law also allows the president to designate materials to be prohibited from hoarding or price gouging.[2] The law does not state what would occur if a business refuses or is unable to complete a request on time. However, any person who performs any act prohibited or willfully fails to perform any act required by the Defense Production Act may be charged with a felony that results in a fine up to $10,000 or imprisonment for up to one year or both.[3][4] The second section authorizes the president to establish mechanisms (such as regulations, orders or agencies) to allocate materials, services and facilities to promote national defense. The third section authorizes the president to control the civilian economy so that scarce and critical materials necessary to the national defense effort are available for defense needs.[5][6][7]
The Act also authorizes the President to requisition property, force industry to expand production and the supply of basic resources, impose wage and price controls, settle labor disputes, control consumer and real estate credit, establish contractual priorities, and allocate raw materials towards national defense.[5]
Yes, under the Defense Production Act.
You said,
Would the govt even have the right to tell Evonik, or any other chemical mfr, that they must ONLY produce Brilacidin-IV until a decent inventory is established?
Bill Gates? Ahhh NO...
Besides, he’s only worth a $113 billion these days. Not sure he can bring enough to the table...
This appears to be the source cited for the Brilacidin mention in that article. Is anyone familiar with this Harrison, C. article?
Harrison, C. Drug researchers pursue new lines of attack against COVID-19. Nat Biotechnol 38, 659-662, doi:10.1038/d41587-020-00013-z (2020).
You said,
Title: Accelerated repurposing and drug development of pulmonary hypertension therapies for COVID-19 treatment using an AI-integrated biosimulation platform - Posted today. Brilacidin is listed with others on page 2.
https://assets.researchsquare.com/files/rs-48619/v1_stamped.pdf
Once again... The sky is falling! The sky is falling!
Thanks! Do you know where that manufacturing will take place? I see where they have 32 sites in North America but they also have sites across the globe, including China.
You said,
Evonik is contracted to produce Brilacidin for us
Good information! I for one am glad to see that steps are being taken to address this very real threat. My doctor is also concerned. When I had my physical a couple of weeks ago, he was talking about how we were too dependent on China for our drugs. He specifically mentioned a known cancer causing agent that was inexplicably being found in some of our drugs that come from China. I did not recognize the chemical and had not heard that story prior to hearing it from him.
Do we know who manufactures our Brilacidin and where? India perhaps?
You said,
It was a brilliant move. Save a US company and get the manufacturing done in the US. A lot, if not most, common drugs can't be made without buying materials from China. This is unacceptable and a national security and health risk.
Since people are supposedly invested in this stock, at least in part, to make money, it is puzzling that some have been here for YEARS posting negative dialogue about this company and its management. How does this benefit their portfolio? How can it possibly benefit them financially to spend SO MUCH of their time being Negative Nellies posting about a stock they do not believe in? It is a puzzlement... or is it...
You said,
Why do people moronically inhabit stock boards for companies they don’t like? It’s a real puzzle? Go IPIX!
I don’t think so. I think that right now Brilacidin is being tested in the lab (possibly those same RBLs) against Zika, Dengue, and a host of other heretofore incurable viruses for which there is no vaccine. Speaking of vaccines, could it be that we will no longer need most of the vaccines we currently have? Maybe that will be the subject of our next PR...
Known as the Swiss Army Knife of drugs, Brilacidin kills bacteria, viruses, and fungi. How much will that be worth?
You said,
Hype will pass and October/November will be elections. IPIX would barely be starting clinical trials missing the boat yet again.
What kind of FUD-busting information is this?! LOL!
You said,
One of the provisions in the just released GOP ‘Heals Act’
$26 billion for development of vaccines and therapeutic remedies to treat COVID-19.
Also another $1200 direct payment for individuals which could mean more IPIX shares:)
If this is true, I will soon own at least 50% more shares!
You said,
This is Leo’s free fall back to $.05 This is his last rooze scamming shareholders.
The sky is falling! The sky is falling! Again...
You said,
Agree, there's no IPIX if COV-19 fails them... Stock would be too low to ever raise money for OM/UP trials. Not getting an OM deal was the clincher as COV19 just prolonged the pain. It did provide one last chance to sell above 10 pennies where Leo got his 6 million.
Another 20% and my stink bids will start filling! I’d like to sincerely thank those spouting FUD for allowing me to increase my ownership stake in this company!
You said,
We are losing 20% per day. Might be in the single digits next week.
So true...
Yet another interesting tidbit that newbys may not know...
Innovation has also submitted a preliminary summary of Brilacidin’s potential for treating coronavirus to the Biomedical Advanced Research and Development Authority (BARDA).
More old news but good news. Newbys might want to pay attention.
Also in April, Innovation disclosed it was in talks with health care provider networks and hospitals in the U.S. and Europe to “rapidly” advance Brilacidin testing into human trials, and announced a study published in the International Journal of Infectious Diseases supporting Brilacidin’s direct inhibition of SARS-CoV-2, based on testing on Vero cells. According to Innovation, the antiviral activity showed Brilacidin’s 3-in-1 therapeutic potential—antiviral, anti-inflammatory, antimicrobial—against COVID-19 and associated complications. In other indications, the company said, Brilacidin has shown the ability to inhibit interleukin-6 (IL-6) and other pro-inflammatory cytokines and chemokines identified as key drivers in worsening prognoses of COVID-19 patients.
Old news but still good stuff!
A week earlier, Innovation announced publication of a preprint study in ChemRxiv by researchers from Argentina’s Universidad Austral identifying Brilacidin as one of 12 most promising potential inhibitors of SARS-CoV-2, based on molecular screening of 11,552 compounds.
Please provide links to support these otherwise baseless accusations.
You said,
He stiffed Menon. He stiffed Cummings (landlord). He may have stiffed Bertolino.
You need to step up your game. I’m having to raise my GTC stink bids.
You said,
Big selling going on... No surprise after another week of no funding... We are being had like OM/Absssi/P. Same pattern of email deception with no plan to raise capital... The MFO is making all the money in this...
Please post a link, unless your statement is just more BS.
You said,
Operation Warp Speed is over, they've chosen the players involved. Now it's a race between 8 companies to see who wins.
Pete - YOU YOURSELF said that out of 15% royalties;
They pay IPIX 6% so their net is 9% of sales and in a market of 17B/yr or so without that much competition that would result in extremely nice income for them.
I’m not trying to be difficult, but you also said that out of 15% royalties:
They pay IPIX 6% so their net is 9% of sales and in a market of 17B/yr or so without that much competition that would result in extremely nice income for them.
I think you made a mistake. It’s 6% of product sales, not 6% of what FCCDC receives.
As I understand it, this is correct.
They pay IPIX 6% so their net is 9% of sales and in a market of 17B/yr or so without that much competition that would result in extremely nice income for them. Not sure how any revenues or payments are aligned between FCCDC and U of Penn but I am sure both will win.
So if sales are $5B /yr FCCDC gets $5B x .15 = $750MM from BP
FCCDC pays $750MM x .06 = $45MM to IPIX
The market cap for the situation you describe (assuming a PE of 20) would be over $2.1 billion. Assuming 330 million outstanding shares, that’s $6.44 per share. If it works really well and garners 50% of the market, then that would be a $10 billion market cap and a $32 price per share.
You quoted RP:
Global Antifungal Drugs Market is expected to rise from $13,719 million in 2016 to $17,718 million by 2023. The industry is anticipated to register a CAGR of 3.7%, during the forecast period, 2017 - 2023.
Imagine penetration of just 10% of the antifungal market, and 6% of net for that.
I’ve been investing in this company since 2013. I know what I own. This company does NOT have a “criminal history.” The real “criminal” is the coward who hides behind the pseudonym “Mako” and he authored one of the articles you linked. I, along with most of the others on this board, have done our due diligence and will not be scared off by FUD.
I think you may have hit the nail on the head!
You said,
...why not capture rights to an indication in your own wheelhouse before a big fish comes along and swallows up everything...? Is that what FCCDC is doing?
“The sky is falling! The sky is falling!!!”
LOL! As long as you are posting, we know to keep buying!
I don’t see what’s puzzling about it but I really like your moniker for Brilacidin - The Swiss Army
Knife of Drugs. The truth of that moniker when attributed to Brilacidin just puts a smile on my face.
Yet again we see more 3rd party validation that puts the lie to most of the FUD we see on this board.
I agree. But saying that you are not going to buy more shares without knowing the MOA implies that you don’t think Brilacidin can be successful without knowing the MOA. If it stops this Coronavirus, Brilacidin will be a success regardless of whether we understand the MOA. I certainly agree that knowing the MOA is important and they should be proceeding with the diagnostic tests necessary to try to determine the MOA. I just don’t understand making your purchase decision contingent on discovering the MOA. But to each his own...
BTW - That’s RBL (Regional Biocontainment Laboratory).
Edited to add: My wife just told me that this post sounds “snarky.” Please know that was not my intention.
You said,
I never said approved
What I said is that the BRL should be running many diagnostic assays test to determine MOA
Are you saying that there has never been a drug approved whose MOA was unknown? Because I do not think that is correct.
You said,
I won't buy another share until I see the published mode of action that the researchers at BRL at Rutgers are investigating as we post here.
Let's try to be logical in our approach, so far we have an antibiotic (not a documented antiviral) that is somehow lowering viral load after pretreatment with Brilacidin in human lung tissue
The reason I think that this is unlikely is because a combo drug would have to start over with a new Phase 1 to make sure there were no safety issues with the combination. Adverse events from drug interaction is a real thing. I think that Petemantx had the right idea. Mentioning Gilead was a PR move to attract the attention of Gilead investors to IPIX. The reason to combo is we get to ride Gilead's powerful and rich coat tails through the regulatory process. Glory to King Gilead so long as we get our cut of the spoils.
You said,
I thought I was at “maximum holding” as well. But when the announcement came that we would not be starting the Covid trial until the 4th quarter, I put in some stink bids below $.20. I guess there’s no chance now that they will ever fill.
You said,
just waiting for the liftoff, not worried about pennies when it will be dollars. At maximum holding right now.
I wholeheartedly agree. And I hope that Leo did get the idea from reading this board.
You said,
First off, why pay for Rems... in a cocktail as it is expensive and is contributing next to nothing?
Secondly, IPIX likely put Rems..../Gilead in the PR so as to capture all the eyes that have alerts in place for any article mentioning them. Great way to spread our Brilacidin success to the many, many eyes following Gilead. This idea was mentioned in a prior post by someone on this board and I thought it highly appropriate.