Please do not attempt to guess at what I have and have not done on RVVTF. When did they apply for their EUA? RLFTF did on 09/17. Groovy man..k

JB

SELL MORTIMER SELL!!

This ship is sinking fast!

SELL MORTIMER, SELL!!

This ship is sinking fast!

RE: New job posting by Nephron for night and weekend

"- Understands EUA (Emergency Use Authorization) regulations"

That's an odd sentence to put in a job description...

https://nephronpharm.hrmdirect.com/employment/job-opening.php?req=1322258&&&nohd#job

So Nephron is looking for someone to work nights & weekends to produce "some" inhaled EUA drug.
- They are our partner
- They make inhaled drugs
- They are going to produce something 24/7
- Whatever it is, it seems it is going to have an EUA
- I'm still in the market for a Gulfstream G500 or better if anyone has any leads

Best,
JB

Comparing it to Penicillin is a BOLD statement

"Vasoactive Intestinal Peptide has demonstrated an immediate clinical response in some patients with COVID-19 respiratory failure. A response of this magnitude has previously not been seen with an antiviral agent and is akin to the first reports of penicillin in treating pneumococcal pneumonia. Similar results have been demonstrated in acute respiratory distress syndrome caused by sepsis."


https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3670129

Best,
JB

INTRO Editing: Send me a PM with any things you would like up there, any suggestions etc. Just getting ready as we will have an influx of new investors looking at OUR board (yes, its YOUR board too) very very soon

Best,
JB

Just think about some things:

- How much is effective treatment for a global pandemic that has crippled every country on earth's economy worth?
- How much is effective treatment for most other respiratory illnesses worth in addition?

A couple billion (2.5 x X)? I would disagree, I think more than anything we have seen in our lifetimes

If you have done any DD on RLF-100, ask yourself:
- If my mother was in the ICU with COVID, what treatment would I want to ensure she had?

I don't know about you, but I wouldn't let her take Remdisivar and would have immediately ensured she received RLF-100 as one of the very first steps upon the first steps upon admission.

This isn't just because of some "confirmation bias" that I have. Soon the whole world will know what we have known for some time. GEM is an investor just like us, they too will want their ROI at some point. It will not be done by selling their stake on the open market, it will be BIG... very BIG. There has already been at least one offer for the company that has been turned down. Soon one will come that will be too lucrative to turn down. GEM is waiting, you should too. Ignore the daily noise and stay long

Best,
JB

It is coming, other factors are at play

How would the rollout of a therapeutic being developed as part of the strategic national defense be handled? I assume quietly..

Odd events today:
-Changed the SSRN paper today
-Removed the Edison award nomination

NRX & RLF seem to have a reason to not want to be frontpage just yet... it is coming though... THIS IS BARDA!!!

Best,
JB

There will be more results published soon


There is intentionally a "under promise, over deliver approach being taken" for a reason. There is a reason not being listed on BARDA site but it has a disclaimer that
"This page is updated regularly, but may not include all awards"
https://www.medicalcountermeasures.gov/app/barda/coronavirus/COVID19.aspx?filter=therapeutic

I doubt they just forgot about them... Its coming to those wait. Some are excited about 6, then 21, then 48 ... how about 288

https://racetoacure.stanford.edu/clinical-trials/486

Stay long and hold

Best,
JB

Good things come to those who wait


"The stock market is a device for transferring money from the impatient to the patient."
- Warren Buffett

"Patience is bitter, but its fruit is sweet."
- Jean-Jacques Rousseau

Some have been saying "I'm out by Jan 1 if no approval" and I thought about the Buffett quote. I have indicated I am LONG in this with almost 5m shares, part of a group that has 130m shares... for me that means I will be holding my RLF AG shares probably for a few years. How long has GEM been waiting for their ROI? Waiting a few months is nothing and there are plenty of other get rich quick schemes out there, many bashers here are involved in them even.

I ensure I cherish every moment on earth that I have and do not obsess over my investments since DD is done prior to making an investment. If you have done yours, relax and do the same -- spend time with loved ones. This is basically a done deal: who, when, how much

Best,
JB

"Who,When,For How Much?"

I'm going back to bed... 4 glasses of Pinch last night (My favorite Scotch,and its a blend!) makes for rough mornings

Cheers,
JB

RE: I wonder....Since we have known about vip a long time.

There are countless studies and papers available on VIP and its relationship to many ailments:

"A vasoactive intestinal peptide antagonist inhibits non-small cell lung cancer growth"
https://pubmed.ncbi.nlm.nih.gov/8389448/

This pdf has citations to many others as well:
https://www.neurorxpharma.com/wp-content/uploads/2020/07/investigators-brochure-version-10.pdf


Best,
JB

Just Listen to Dr. Rick Roll Discuss VIP!

ONE PATIENT WILL NOT DETERMINE RLFTF'S ENDPOINT

For weeks there was constant discussion about ONE PATIENT who was recieving RLF-100 and as you saw had zero effect on the stock,company or anything for that matter. Now there is constant chatter about ONE PATIENT who IS NOT RECIEVING RLF's drug. 50k other Americans were diagnosed yesterday, the vast majority are not receiving RLF-100 either. PLEASE KEEP YOUR POSTS RELATED TO RLFTF, THIS IS NOT A "GENERAL NEWS" BOARD... FFS!!

JB

Have been assuming Nephron since last Yo video

They are the first and pretty much only google result when searching for "sterile inhaled pharmaceuticals". We also called Mckesson the same day as Nephron. I know many have seen these in my PMs, just putting it out there publicly now.

As far as news & what this means -- well the writing is on the wall. I even heard yesterday from the horses mouth "by November". So that it what's next BUT you need to be resilient since this is only the beginning. Far more is to come which will take the share price to the moon. 10-100 bagger with a buyout of 50-150B are our scenarios.

The RLFTF runaway train has now departed the station and this is just the beginning of the journey. More news will hit in increasing succession and at some point the after burners will kick on. Hold tight and be the old big brass bull to wait for ALL of that new RLFTF money!!

Cheers,
JB

RE: That just surfaced this morning

HUH?! The video/article on RLFTF CLEARLY had a date stamp of 09/24/20 visible to those that read the article.

DIAF,
JB

Just the beginning of what is to come

==========
DD post by: Mount Pilatus (Another Board)

https://patents.google.com/patent/US8178489

Example 6
The following provides clinical examples for drug dosages, safety and efficacy for inhaled administration by chronically ill patients of the medicament formulation at pH values between 5.3-6.0.

Post-VSD

A patient suffering from pulmonary hypertension associated to post-ventricular septal defect (post-VSD) inhaled 100 micrograms of Aviptadil as a single dose without any irritation of the lungs. The efficacy of the medicament is demonstrated by a decrease of 21% in pulmonary vascular resistance consisting of an increase of cardiac output and decrease of mean arterial pulmonary pressure, while having no systemic side effects, and as compared to the patient's baseline characteristics. The daily dose for that patient comprises 400 micrograms split into 4 single dosages of 100 micrograms of Aviptadil each. Thus a weekly dosage for such a patient is 2800 micrograms Aviptadil.

IPAH

A patient suffering from idiopathic pulmonary arterial hypertension (IPAH) inhaled 100 micrograms of Aviptadil as a single dose without any irritation of the lungs. The efficacy of the medicament is demonstrated by a decrease of 20% in pulmonary vascular resistance consisting of an increase of cardiac output and decrease of mean arterial pulmonary pressure, while having no systemic side effects, and as compared to the patient's baseline characteristics. The daily dose for that patient comprises 400 micrograms in 4 single dosages of 100 micrograms of Aviptadil each. Thus a weekly dosage for such a patient is 2800 micrograms Aviptadil.

CREST Syndrome

A patient suffering from pulmonary hypertension associated to scleroderma (CREST syndrome—Calcinosis; Raynaud's disease; loss of muscle control of the Esophagus; Sclerodactyly; Telangiectasia) inhaled 100 micrograms of Aviptadil as a single dose without any irritation of the lungs. The efficacy of the medicament is demonstrated by a decrease of 14% in pulmonary vascular resistance mainly consisting of an increase of cardiac output, while having no systemic side effects, and as compared to the patient's baseline characteristics. The daily dose for that patient comprises 400 micrograms split in 4 single dosages of 100 micrograms of Aviptadil each. Thus a weekly dosage for such a patient is 2800 micrograms Aviptadil.

Extrinsic Allergic Alveolitis

A patient suffering from pulmonary hypertension associated with extrinsic allergic alveolitis inhaled 100 micrograms of Aviptadil as a single dose without any irritation of the lungs. The efficacy of the medicament is demonstrated by a decrease of 21% in pulmonary vascular resistance consisting of an increase of cardiac output and decrease of mean arterial pulmonary pressure, while having no systemic side effects, and as compared to the patient's baseline characteristics. The daily dose for that patient comprises 400 micrograms in 4 single dosages of 100 micrograms of Aviptadil each. Thus a weekly dosage for such a patient is 2800 micrograms Aviptadil.

Chronic Obstructive Pulmonary Disease

A patient suffering from pulmonary hypertension associated to chronic obstructive pulmonary disease inhaled 100 micrograms of Aviptadil as a single dose without any irritation of the lungs. The efficacy of the medicament is demonstrated by a decrease of 20% in pulmonary vascular resistance consisting of an decrease of mean arterial pulmonary pressure, while having no systemic side effects, and as compared to the patient's baseline characteristics. The daily dose for that patient comprises 400 micrograms in 4 single dosages of 100 micrograms of Aviptadil each. Thus a weekly dosage for such a patient is 2800 micrograms Aviptadil.

A patient suffering from pulmonary hypertension associated to chronic obstructive pulmonary disease inhaled 200 micrograms of Aviptadil as a single dose without any irritation of the lungs. The efficacy of the medicament is demonstrated by a decrease of 25% in pulmonary vascular resistance consisting of an increase of cardiac output and decrease of mean arterial pulmonary pressure, while having no systemic side effects, and as compared to the patient's baseline characteristics. The daily dose for that patient comprises 800 micrograms in 4 single dosages of 200 micrograms of Aviptadil each. Thus a weekly dosage for such a patient is 5600 micrograms Aviptadil.

Example 7
The following provides clinical examples for drug dosages, safety and efficacy for infused administration of the medicament formulation at pH values between 5.3-6.0 for patients with acute life threatening conditions like respiratory distress syndrome due to sepsis, burns, gas intoxications, and ischemia.
==========

There are even more historical examples of Aviptadil being used and tested for a wide array of ailments (if you look and read). I suppose some get overly excited over television stories such as the one @chris on that other board posted this AM, for their RLFTF information as opposed to true DD on RLFTF which requires reading....

JB

Significant Slaps are happening today with RLFTF...

Most informative post I have seen in a while regarding RLFTF. We even have information to validate most of these thoughts that he has publicly conveyed in his post. Almost 60 days of nothing and then one of the most informative posts to date on RLFTF IMO!!!.


WELL DONE NOTOS!!!!

Best,
JB

RE: That article is worthless at this point.

The article is far more valid and informative about RLFTF then the baseless claims about pending "approval this week" or "the share price is going to be $x" made about RLFTF since it is an interview with a member of Operation Warp Speed. Sourced statements from Moncef Slaoui carry far more weight than any predictions since he has access to far more information about upcoming vaccines and therapeutics

JB

Find positions where you believe in RLFTF
Understand its potential compared to where RLFTF is
Consider the RLFTF risk vs reward
Know RLFTFs competitors and if they are better

Your emotions have no bearing on RLFTF
Only facts and information matter w/ RLFTF
Utilize Due Dilligence on RLFTF

When you have a high degree of confidence, buy RLFTF
Have a venture capitalist mindset w/ RLFTF
Attain as much information as possible on RLFTF
Let your RLFTF investment play out longterm
Enjoy making money of RLFTF and remain humble

Attempting to predict RLFTF share price upon EUA being granted and the timing of EUA being granted is futile. IF you have backup or a basis for it, post it up please.

JB

"Two COVID-19 vaccines and two drugs that reduce mortality from the disease will be authorized by the end of 2020, Moncef Slaoui, chief scientific adviser to Operation Warp Speed, predicted in an interview with BioCentury."

https://www.biocentury.com/article/630710

Taxes ...


Because there are excessive posts about additional "scary" RLFTF taxes: there is no concern and this is no different than any other ticker. By investing, you are not working out of the country for a foreign company as some have indicated. Prime example: I have bought and sold Roche AG countless times over the years, I have paid people to advise me on a vast amount of financial aspects(I don't know everything :) and I have a paid company to do my taxes as they are long and complex(not some H&R Block rinky dink)

Short answer: There is ZERO concern for additional tax implications for trading a stock of a foreign company from the base country or your own. It is the same as any other stock for your tax purposes.

Best,
JB

A September 17th row of ducks...

"As part of this agreement, the federal government will hold a reservation for 24 hours a day 7 days a week fill/finish capacity production on commercial filling lines for use by federal partners that are developing COVID-19 vaccines or therapeutic treatments."

https://www.medicalcountermeasures.gov/newsroom/2020/ologybio/

Best,
JB

RE: Seeing that this forum has a way

Perhaps in your world view no one reads this board but I can assure you that is not the case. I have long stated publicly that my group & I are treating this as a venture capital play. We could move this thing ANYWAY we wanted based on the volume we own honestly BUT the risk is that a significant catalyst could take place or be initiated by the company who are DEFINITELY NOT in on any manipulation.

When the company is too, it can be very very bad for them (and investors)
See for reference: https://www.pacermonitor.com/public/case/36207454/Alpha_Venture_Capital_Partners_LP_et_al_v_Pourhassan_et_al

Stating unsubstantiated "potential blips in the road that could cause issues" with ZERO basis only causes people to believe you have a small OTC mindset on this ticker.

I was "assigned" to this board btw to keep our ears to the ground. I am not the only one who serves this role for a group not the only member of our group with a place to be. Always remember that when you think you are big and powerful, there's always someone bigger and more powerful out there -- this is not your typical OTC penny flip my friend. If it was you would see us making more than waves, we make tsunamis!

Best,
JB

RE: Anyone else feel like this ticker is going

We have ZERO concern about this. You do realize RLF AG is a foreign company and listed on a foreign exchange right? They were not technically even at either conference. The SEC has no jurisdiction over RLF AG and these events are immaterial and were even made public soon after.

I'd swear you are now trying to stoke fear in hopes of getting a position back in. If so, given your time here I'd assume you would know that is not going to work. If not, do some DD and post links to justify your scare tactics

"Many equities are Penny Stocks. Penny stocks can be very risky, and investors should be aware of what type of security they are trading before making any investment decision. Due to the high level of risk involved in investing in penny stocks, a broker-dealer cannot sell them to a client unless it has approved that client's account for penny stock transactions, and the broker-dealer has received an agreement to the transaction in writing from the client. See: Penny Stock Definition, Schedule 15g. Penny Stocks are not permitted to join the OTCQX market."
https://www.otcmarkets.com/learn/investor-protection


All the best,
JB

RE: Here is the link to JJs speech

If you haven't seen already, you must watch...

https://view.vzaar.com/22010741/player

Not sure if now was the best time to have it public for several reasons, but it is what it is

Might as well pin it now, the cat is out of the bag. This runaway train is about to leave the station and just announced "All Aboard!!"

Best,
JB

RE: FDA poised to announce...

You know it would really help if you posted backup for some things you indicate about RLFTF. This one oddly does check out though...

https://www.forbes.com/sites/jemimamcevoy/2020/09/22/report-fda-to-announce-tougher-coronavirus-vaccine-standards-that-may-dash-trumps-election-day-goal/

Best,
JB

Bloomberg posted the 09/21/20 PR

EQS-News: Relief and NeuroRx Announce Partnership for Global Commercialization of RLF-100(TM) and Selection of Commercial Partners

https://www.bloomberg.com/press-releases/2020-09-21/eqs-news-relief-and-neurorx-announce-partnership-for-global-commercialization-of-rlf-100-tm-and-selection-of-commercial

My take on the RLFTF press release:

What an odd press release to (re)announce the NueroRX + RLF AG partnership. Filled with detailed percentages of their profit sharing arrangement etc

I assume this was put together for "1 person" in particular who would want to see a US company reap the benefits before "signing off" on grant money and the proceeds of 100's of millions of pre orders for the drug. I think the dumptrucks full of cash are being filled and someone wanted to see something that indicated that money was going to stay in the US.

Just relax, hold tight and enjoy the ride. October surprises are a thing

Best,
JB

The COVID-19 "Dream Team" !!!


DD From Jason (AKA ALL CAPS) on another board
============================

ALWAYS GOOD TO KNOW WHO IS ON YOUR TEAM...WITH THE TALK OF REP. HARRIS GETTING FLAK FOR HIS BIOSTATISTICS EXPERIENCE..READ A LITTLE HERE ABOUT NEURO RX CHIEF METHODOLIGIST Philip T. Lavin, PH.D.,

Dr. Lavin is a highly-respected biostatistician with more than 30 years of experience supporting the design and analysis of clinical trials. Previously, he was a member of the biostatistics faculty at the Harvard School of Public Health and a member of the Department of Surgery at Harvard Medical School where he was affiliated for over 25 years. He co-founded Boston Biostatistics in 1983, a company now known as Aptiv Solutions. During his career, Dr. Lavin has served as lead biostatistician for 50 FDA approvals, including 38 PMAs, more to date than any other biostatistician. He has also served as a Special Government Employee for 30 years where he has advised FDA on complex statistical and policy issues.

READ THAT 2ND TO LAST SENTENCE ONE MORE TIME...HE IS THE GOAT OF FDA APPROVALS. MAN WE ARE STACKED....

====================

Further evidence that we have an All Star Team leading the charge!

Best,
JB

Patent Title
Use of compounds having the biological activity of vasoactive intestinal peptide


I asked you to read the patents, that's just the title, look at the first word of the title.

So it covers the USE of a peptide or one similar to VIP....

I got out of Phase a while ago, should they ever try to bring their VIP compound to market, our small staffed holding company (RLFTF) will surely seek litigation. I am not alone in thinking they would have a very very strong case against Phase. They haven't done it yet since there is no need to. How great is it to have another company test something you hold a patent on for free.

Go ask a patent attorney their thoughts , I have talked to two about this exact issue. I would suggest more DD rather than stoking unsubstantiated claims with no backup.

Doing this in public benefits neither of us like Mark Twain said. I was trying to save you from yourself. I have the law & facts on my side -- pound the table all you want. I do not wish to engage in this trivial discussion attempting to enlighten you further.

So in short, I'd agree with you but then we'd both be wrong.

JB

RE: they own the patent for their synthetic version

This is not entirely correct, read the patents...

I am not interested in any debate or conflict of any sorts btw -- Especially in a public forum.

Best,
JB

RE: Whalatane


They have the intellectual property rights:
https://patents.google.com/patent/WO2009039991A2/en
https://patents.justia.com/patent/7951778
https://patents.justia.com/patent/8153599
https://patents.justia.com/patent/8178489
Any other VIP formulation would have a tough fight to make it past these

Best,
JB

We are invested in a holding company (RLF AG) that the largest shareholder is and has been a large investment group (GEM). They have always been in control of RLF AG and continue to be.

We just do not see RLF AG building manufacturing facilities and expanding drug portfolio to try to become yet another player in a crowded field of other heavy weights.

Our group has all concluded that the offers will come, some will be too lucrative to not be considered. Extensive licensing deals are a possibility but at some point they will want to get their payday. The amount of shares they own and would release into the wild makes that scenario less likely as it would tank share price.

My group owns about 5% of the company cumulatively. We have hitched our wagon to GEM's and are holding. We have committed to not releasing ANY shares until we reevaluate in 02/21 unless a buyout occurs priors. The amount of available shares in the public float is far less than many here believe.

We also feel we are not the only ones with large positions and smart money has already been "holding" like us. There have also already obvious indications of attempts to shake loose shares by some unknown entity.

Risk making pennies here and there at the risk of missing out on thr most historic rise in our lifetime if you want but once again, smart money is holding. Buckle up, follow along and enjoy the ride.

Best,
JB

Valuation is impossible atm but if I'd guess how much the company was sold for, my "guess" would be 100B+ easy... Its just that though, a guess....

Effective treatment for a global pandemic afflicting millions and disrupting world economies, what is that worth? Oh you say it might help with other respiratory afflictions too, stack that valuation on top of the pandemic treatment value as if even it matters. Until I have some sound rational idea(Not for the foreseeable future), I'm not moving anything. 0.2% Minority Owner, see you at the annual shareholders meeting!

Best,
JB

RE: Sheeesh...focus on Monday

Do not focus on Monday or expect much if anything from Monday. This is not how "breaking news" for RLFTF will be conveyed. There will be a great deal of networking and some new interest in RLFTF but some fools focused on Monday might be prone to releasing RLFTF shares due to no "breaking news". SMH...

JB

RE: aGuyUS. well since U took the time

You have to be kidding. You think he is just spinning his wheels charting/analyzing RLFTF and other stocks and needs to take a break?

Do you not realize he knows what he is doing? Well here, I will share a RLFTF chart which "surprisingly" lines up with what you failed to comprehend.

https://imgur.com/a/dXJR5Yo

Psssh ... kids these days


Best,
JB

Ask yourself why you own RLFTF shares

Did you purchase some shares because you were hoping to gamble on the OTC's rather than lotto? Did you want some shares in a symbol with high volatility so you can buy low & sell high on the swings?
Did you want to see if you could tangle with "traders" with much less capital as those on the big exchanges but who employ questionable if not illegal manipulation techniques? Did you just want somewhere to come argue with fellow investors and freely spout off what random 2 word thought you feel everyone cares about?

Well I can tell you that none of those reasons apply to my investment group or myself. We believe VIP's efficacy & safety for COVID ARDS treatment is undeniable. We believe in RLF-100 as being the most likely VIP candidate to be first to market and my RLFTF position is 46k every penny it moves.

Here is some info our group used to "invest" in RLFTF:

It is ALREADY approved in the US:
"Relief Therapeutics holds FDA orphan drug designations for the use of VIP to treat ARDS, pulmonary hypertension, and sarcoidosis."
https://www.clinicaltrialsarena.com/news/relief-aviptadil-covid-19-trial-us/

It is ALREADY approved in the EU:
"On 28 August 2006, orphan designation (EU/3/06/395) was granted by the European Commission to mondoBIOTECH Laboratories, Lichtenstein, for Aviptadil for the treatment of acute lung injury."
https://www.ema.europa.eu/en/medicines/human/orphan-designations/eu306395

RLF AG realized what they had might be beneficial to COVID ARDS treatment
https://www.reuters.com/article/brief-relief-therapeutics-to-test-rlf-10/brief-relief-therapeutics-to-test-rlf-100-for-treatment-of-covid-induced-ards-idUSFWN2B91WW

RLF AG teams up with a "Tom Brady" in the pharma industry to get their drug through FDA process
https://www.clinicaltrialsarena.com/news/relief-aviptadil-covid-19-trial-us/

US Trial progressing
https://clinicaltrials.gov/ct2/history/NCT04311697?A=1&B=5&C=merged

Paper on 21 CONSECUTIVE patients too sick for trial
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3665228

They have the intellectual property rights:
https://patents.google.com/patent/WO2009039991A2/en
https://patents.justia.com/patent/7951778
https://patents.justia.com/patent/8153599
https://patents.justia.com/patent/8178489
Any other VIP formulation would have a tough fight to make it past these

Many will try to shake you loose from your RLFTF shares with doomsday penny stock prophesies etc. Many will get scared watching the price change daily (That is kind of what stocks do btw). Many want RLFTF to have a daily PR machine like CY** but with no results. If you need these things, RLFTF might not be the best place to put your money.

RLFTF has all star team handling the roll out of the most promising therapeutic developed in our lifetime. Efficacy & safety have already been demonstrated. If anyone else I know contracts COVID, I would surely be pressing them to seek Aviptadil -- my wife,kids,self as well. That is how much faith I have in the product which relates to how much faith I have in my RLFTF position. It is an "investment" that I plan to hold onto for quite some time. Our group(130m+ RLFTF shares) is doing the same. GEM is doing the same. We all know at any day the runaway train can depart the station.

Best,
JB

Our take is that the approved IV will be the main asset and the inhaled will be the future "carrot", both will be heavily considered for the sale of the company. Just guessing but 100B+ would be easily attainable

Best,
JB