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Thanks for adding some perspective.
Enjoyed the jab….enjoy the holiday.
Bigger chatted that he added on Sept 24th. Low for that day was around $1.38. Perhaps he’s chatting up the equity raise price to keep his open market purchase from looking bad?
(No surprise algorithms that foment negativity has been the most viable business model for FB)
Or DI making the subtle change replacing “finish” with finished…..
Agreed as well as vator’s subsequent post.
There is a tit-for-tat paying out between AF and Bigger. IMO initiated by AF with blog on Wednesday as no doubt he knew Bigger was going to be in Bethesda last Thursday. AF is intentionally provocative (click bait) as he’s on a pay site. Bigger is having fun, partially at AF’s expense, on holiday. I hope Bigger enjoys his holiday and lands a few more jabs via Tweet for the public to enjoy.
Assuming Bigger met with management while in Bethesda on Oct 8th, or even if he didn’t meet with management his subsequent tweet on Oct 10th below is not extolling confidence in his investment? An investment he tweeted on Sept 24th “added”.
Appreciate the sarcasm Doc……coming from one who has been more than a tad bit flippant of late.
Some skilled practitioners from the EU too.
I’m digging Bigger’s style a little more.
Agree. And solid data from the L trial would certainly backup the draft guidance…..think I posted something along the line of paving the way for future trials. If so it would make the wait somewhat more palatable for most.
Thanks, does make one wonder if the L trial, with all its “never going to see results” length, helped influence the draft guidance.
Long cool holiday.
Since the system will most certainly be sold/licensed two other contract (CDMO) manufacturers. NWBO/Advent is not the vehicle to do so and should not “own” it. As that would most certainly inhibit adoption. It was prudent for Autolomous to have a (CDMO) manufacturing partner to help develop the system.
It’s conceivable the integration of Autolomous firmware would optimize Flaskworks potential to the point where it could be awe inspiring. Perhaps those doing rational dd on rounds of financing in the industry would be so kind to provide some thinking on the recent round of investment.
I should also add IMO due to the risk of AE’s with the addition of Keytruda I believe it is critical this trial is being conducted at UCLA.
Very cool, thanks.
“negative hit piece” is telling. Must be tough for blogger to keep a stiff upper lip in the face of sagging influence amongst other things…
Perhaps Tuition play will work for me. Visiting IU next week with son and have UC Boulder in future.
Checked his Twitter and it’s a cool one. Dude is on holiday for next two weeks and good for him.
Cool, thanks.
Can we make this a Zoom call?
Further indication of the onset of flaccidity. I trust he can keep a stiff upper lip going forward.
No doubt. You and Poor Man have been noodling this and I have no real meat to add. Except the trial will perhaps be interesting/enlightening from a couple of possible prospectives. One being AE’s (adverse effects) could indicate the effectiveness of the combo and not necessarily be a “bad thing” for this trial. And two, being the possibility of the combo increasing the effectiveness of L to the overall spectrum of glioblastoma subtypes.
Cool, and Advent has one known customer at present.
Dude is consistent-ly ineffectual.
I would wager he is aware of Bigger’s itinerary.
All CI’s (Keytruda included) have some challanges/issues when used as a mono therapy. Would like to think a more directed (pun intended) immune response would bring things into check.
New patent only applies to combination. The Keytruda patent in question expires in 7 years.
(bio answered more completely)
Duffy (bio/pharma free agent) currently at Regeneron
I’ll try not to read anything into his going on holiday the next couple of weeks as my recent track record of picking Canadian (baseball) winners has been less than stellar.
I know vator pointed out there are many entities HQ’d in Bethesda, but is interesting he singled it out with “Washington” on Friday considering Bethesda is essentially D.C. metro area.
Very cool…..and perhaps a precursor.
I own MRK new antiviral pill effective against Covid…..don’t think it’s a repackaged/rebranded Ivermectin.
Should have read: The Yankees foe this weekend.
Head fake…..et tu Sojo???
Varying levels of sophistication on display….but nothing to crow about unless parched.
October with Advent calendar starting early this year.
Win would have been useful for the Canadian team as the team from the west is the concern (bosox are fading). The foe this weekend the Rays should be phoning it in.
Irrational exuberance…..with a dose of hubris. Decidedly not a vaccine fan.
October is ominously looming with it the postseason and start of 4th quarter.
Fair point…….putting compassion in the “compassionate” care programs.
Another win tonight by the Canadian team would be useful as there is another hot hand in play from a team in city I used to live in out west. Wild card games in both leagues will likely have consequence for division series. Not to mention the prevailing Moneyball flavor.