I'm positive. Susan McIntyre may be a nice person but once she finds out what Bavi is all about she will not be interested in trying to make it work essentially cause Bavi doesn't work. But keep peddling those Bavi conspiracy theories.
And of course, Avid is out of the Bavi business anyways!

PS targeting was never more than a pipedream. If anything it is an effect no a cause and thus might have some value as a dianostic not a therapeutic ( if you could even develop a therapeutic to it which Bavi certainly was not). Haven't checked in on this sad stock in a long time but it's good to see some things never change!

PS targeting technology was only disruptive to people's net worth- obviously in a harshly negative manner. SK and his cronies did OK though.

the only one who said the data was tainted was SK and I don't believe him. Read all the publicly available information and you will find SK talking about how CSN relabeled. $600k is close to nothing. It may have been just letting SK out of the last payment CSM was owned. All the information is there you just have to know how to read between the lines. Of course you could just take the word of someone with zero credlibility

that old dog don't hunt.
there was no sabotage. SK didn't understand what a double blind study was and thought that CSM would keep the same labels they PPHM gave them. They did the proper thing and blinded them so when the amateurs at PPHM saw the data they assumed it was in the same order they gave CSM when it wasn't. There never was any "switching" just proper blinding.
These guys stole money from people who thought they were investing in a cure for cancer when they were just giving money toe SK and a corrupt board so they could feather their nests. Disgraceful unethical behavior. How anyone can still be an apologist for these fraudsters is beyond me.

somehow the original post was not including in my message

from Sept 2015 I wrote

"Bavi doesn't work- it's that simple. When the charade is over you will finally see how SK took you to the cleaners."

March 2018
I don't believe the current management of AVID to be fraudulent. They may not know how deep seated the dishonesty of SK and company was before they took over.

the charade is over

I don't think there was an upfront payment of $8 million it's supposed to occur over several months but there are probably ways of getting out of paying the full amount One last scam for Bavi the scam that worked so well for so long. Stay tuned for payment updates.

there is a really good way to know it is no good-

it has never worked in a clinical setting, the MOA has changed 5 times.

most drugs have their targets as receptors or in some cases enzymes. Bavi is to a structural element. Hard to do. Furthermore look at Bavi and you will realize the antibody while described as anti PS is actually allegedly to PS in combination with GPIII a very abundant glyco protein.

Science is not about outcomes determined in advance. You may want desperately for Bavi to work but it simply doesn't and there is scant evidnece other than the cherry picked nonsense from SK and his band of thieves that would suggest that it did.

BP isn't stupid. they kicked the tires and knew Bavi was worthless.
What happened to all the posts claiming a BP conspiracy cause of the awesomeness of Bavi. Kind of in tatters now. I'm surprised they could get anything for Bavi but keep checking back and see if they actually get any payments from Oncologie which seems to not even exist.
Hard to imagine how a company can lose 400 million dollars and come up with absolutely nothing.

You shouldn't be stunned.
King and his band of thieves never said one thing that came true.
They continually tried to claim a new MOA for Bavi depending on what the hot area of biotech was.
You'll never see King again. He was a scammer in the right place at the right time.
He has lost so many people so much money while building his own retirement fund.
He was SK- Scam King

they got maximum value for what is actually worth slightly less than a bag of hammers. Unlike SK what they say is going to happen is what actually happens.
SK and his cronies made more than what the IP was sold for! Chapeau to the scammer of scammers!

hate to break it to you but Bavi doesn't work. It never has in any clinical trial only in cherry picked preclinical studies. If I had a nickel for every time cancer has been cured in mice I would be a rich man. And if you invested a $1.00 in PPHM 10 years ago you would be lucky if it was worth $0.05 today.

CDMO has stated the IP will be divested and they will support zero dollars towards research of the PPHM IP. How much clearer do they have to be.

No one's bashed Adam Feuerstein for a while but PPHM's failure was correctly predicted by the Feuerstein rule.

when you put it that way- I"m all in-

where can I send you all my money?

people that work for Big Pharma/ Biotech aren't stupid. They are also always looking for new therapies. The fact that not a single one thought PPHM was worthy of anything should tell you all you need to know. There was never a conspiracy to ignore PPHM cause it was a threat to Big Pharma. SK and his band of cronies sold you a bill of goods for many many years and some of you put your faith in him. All the while all he did was lose everybody a lot of money.

all excellent questions. My question does SK still have a job? Since there is no more PPHM and it's Avid only and Avid has a President what is there for SK to do?

Sad for all the folks that invested their money, hearts and time in people who would not live up to their expectations

They're still going to plunder as much as they can before it sinks

give SK credit.
It should have been over years ago but he's still padding his retirement account while every single person that has ever been long in PPHM has lost money.

this looks bogus-

there were 3 arms and they're only reporting it as 2 and when the 1 mg/kg and 3 mg/kg are combined it looks better. what they're leaving out is 1 mg/kg out performed 3 mg/kg and the control out performed 3 mg/kg. Phony statistics make it look like bavi has some minimal positive effect but the truth is idoes nothing.

most importantly the fact that they are presenting this at all means there were no vials switched just a misunderstanding on PPHM's part as to what a blinded study is.

the pattern is whatever the industry is headed to all of a sudden Bavi is there

first MOA for Bavi the same as anti VEGF and vascular inhibition bavi only

then Bavi as chemo adjunct

then Bavi with checkpoint inhibitors

now Bavi with exosomes ( a developing but unproven field)

check out the first 3 results 3 complete failures what do you think will happen to the exosome work?

heck I may have even missed an MOA or two

throw in the Bavi image project and Cotara and you have a bunch of zeros.

Now maybe spending less on R and D will be a good thing but it basically means PPHM is shut down.

Wait until the Ronin folks take over and start looking at what really has been going on over there.

look at the PPHM web page
1 phase 1/2 trial listed and a string of phase 1
all using a failed product
will someone please turn out the lights

what the profit on that? maybe a couple of million and they're still losing money with whatever is left of Peregrine. Not much to hang your hat on IMO.

the answer is no.
they are the worst.
how can they be rewarding failure. where is the accountability?

failed the patients, failed the shareholders, success for their bank accounts.

PPHM just admitted there is no PPHM. No Phase 2 or 3 trials. That means like at least 7 years before there is a possible filing.

So instead of a billion $ drug with high profit let's talk about $40 million gross.

Hard to see any value in PPHM.

they've never done that before. It's not in their DNA. I have continually made the case that PPHM has really been about SK and his cronies lining their pockets till the inevitable crash of PPHM comes. Nothing I have seen has caused me to doubt that is what has been happening. The shareholders do not enter into any consideration by SK.

PPHM is essentially done.
There is nothing that is going to turn this around.
They can't even use the ATM at these prices without massive dilution.
You won't even get crumbs from this.

if it's not fake it will do until the real fake gets here

They haven't given one dime to PPHM but PPHM has given them plenty.
These academics have zero allegiance to PPHM shareholders. They're laughing all the way to the bank at the money ( your money from the ATM) PPHM throws at them

why on earth would AZN want PPHM? Then they would have to pay money. Right now everything is on PPHM's dime which is to say the ATM which sucks the life out of your shares.
let me know when something other than the ATM gives PPHM any cash.

there is no more pphm. there is only avid. SK and his band of thieves will try to suck as much of that revenue to line their pockets as possible. Not sure where this leaves Joe Shan or Jeff Hutchins but since they have always toed the party line they will be rewarded by the SK apparatchniks.

this whole cynical affair will not end. shareholders should ask why PPHM ATM was used to pay for the Avid expansion. It should have been used to develop PPHM products. instead it was used as an out for PPHM management.

unfortunately,though your points are legitimate, you have already heard management's response. This was just a set back in the chemo world- it doesn't impact immunotherapy as the MOA is different ( of course since it failed in chemo one would have to wonder what the MOA was for that!). We have promising collaborations with top tier companies and medical institutions ( never mind that PPHM is the one paying for everything and no one beat a path to PPHM's door to collaborate).
All is well!!
We have cash ( to fund SK's retirement!)
I keep thinking this is the last year but with $60 million in cash PPHM can hang around for a little bit until all that cash is gone- wasted on the salaries of the folks who are running the company into the ground.

PPHM has $60 million in cash
The market cap is $98 million
PPHM is effectively worth $38 million.
That is a truly pathetic value considering a net loss of close to $500 million for its history.
King and his cronies have gotten rich while producing nothing.

this collaboration as all other PPHM collaborations will come to nothing. This was solely instituted so that there would be something good to talk about after the dismal Sunset of SUNRISE ( wasn't it odd that shan said they would discontinue enrollment that was supposed to have been completed already). Basically a $2 million PR. And yeah I'd rather had $25 million in revenue from Avid against $24.9 million cost of goods than a blockbuster drug making billions every year. Seems like a fair trade.

you make an excellent point. why on earth would they say the Doce only arm outperformed but to try and put a positive spin on what is certainly a complete disaster.
Here we have people living longer on Doce alone and PPHM acts like it's a bad thing. If they weren't looking for weeks improvement in survival it wouldn't even matter. So cynical to not even bother thinking cure but thinking we get a few weeks extra we might be able to get approval.

there is no way forward. They have $60 million in the bank and the market cap is $90 million that means PPHM ( including Avid) is worth $30 million. They will limp ahead and SK will continue to be paid. One good thing is that if they stop all the trials their cash will last longer. They do need some cash to pay the preferred shares and the crazy salaries of the gang that couldn't shoot straight as well as Garnick's $500 an hour.

There was never a doubt it would end this way, not with a bang, but a nice retirement in Orange County for SK.

Bavi doesn't work - the only thing artificial is the hype PPHM made around it. The reality is that SK and his gang that can't shoot straight is getting rich on ATM. None of this is surprising,

PPHM is done. There never was any science other than the observation that cells are already dying have PS on their outer membrane. SK is a fraud who was solely interested in lining his own pockets. This latest debacle cannot be considered a success. And CSM had nothing to do with this. THe only sabotage was coming from PPHM management sabotaging your share price.

I'd like to personally thank the management of PPHM for always making it a good time to buy this stock. Pretty sure SK and the gang that couldn't shoot straight have almost filled their retirement accounts. Too bad it's the reverse for the loyal shareholders.

How's that SK management working out for you. The real shell game is that most of Avid's revenue comes from PPHM atm