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Anavex Life Sciences Corp (AVXL)

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Last Post: 2/19/2018 7:14:13 PM - Followers: 714 - Board type: Free - Posts Today: 94

Anavex Life Sciences Corp (AVXL)

Company website:
Company Address:
51 West 52nd Street, 7th floor
New York, NY
10019 USA

CIK:  0001314052

Anavex®Life Sciences Corp. (the “Company”) is a clinical stage biopharmaceutical company engaged in the development of differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental diseases including drug candidates to treat Alzheimer’s disease, other central nervous system (“CNS”) diseases, pain and various types of cancer.  The Company’s lead compound ANAVEX®2-73 is being developed to treat Alzheimer’s disease, Parkinson’s disease and potentially other central nervous system diseases, including rare diseases, such as Rett syndrome.

Anavex®Life Sciences’ lead drug candidate, ANAVEX®2-73, recently completed successfully a Phase 2a clinical trial for Alzheimer’s disease.  ANAVEX®2-73 is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors.  Preclinical studies demonstrated its potential to halt and/or reverse the course of Alzheimer’s disease. It has also exhibited anticonvulsant, anti-amnesic, neuroprotective and anti-depressant properties in animal models, indicating its potential to treat additional CNS disorders, including epilepsy and others.  The Michael J. Fox Foundation for Parkinson’s Research has awarded Anavex® a research grant to develop ANAVEX®2-73 for the treatment of Parkinson’s disease to fully fund a preclinical study, which could justify moving ANAVEX®2-73 into a Parkinson’s disease clinical trial.  ANAVEX®3-71, also targeting sigma-1 and M1 muscarinic receptors, is a promising preclinical drug candidate demonstrating disease modifications against the major Alzheimer’s hallmarks in transgenic (3xTg-AD) mice, including cognitive deficits, amyloid and tau pathologies, and also with beneficial effects on neuroinflammation and mitochondrial dysfunctions.

The Company is in preparation for ANAVEX®2-73 for a Phase 2/3, placebo-controlled trial in Alzheimer’s disease as well as a Phase 2, placebo-controlled trial in Rett syndrome, for which the U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation (ODD) for ANAVEX®2-73 and a Phase 2, placebo-controlled trial in Parkinson’s disease.

Headquartered in New York, Anavex® Life Sciences is an American publicly traded corporation on Nasdaq quoted as AVXL


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AVXL News: Amended Statement of Ownership (sc 13g/a) 02/14/2018 05:49:32 PM
AVXL News: Anavex Life Sciences to Present at the 2018 BIO CEO & Investor Conference 02/08/2018 07:00:00 AM
AVXL News: Quarterly Report (10-q) 02/07/2018 05:05:16 PM
AVXL News: Anavex Life Sciences Provides Clinical Programs Update and Reports Fiscal First Quarter 2018 Financial Results 02/07/2018 07:00:00 AM
AVXL News: Anavex Life Sciences to Announce Fiscal First Quarter 2018 Financial Results and Provide an Update on Clinical Programs and C... 02/05/2018 07:00:00 AM
PlusOneCoin Top Posts
#141363   DD re: discussion of genome sequencing database: This is Biostockclub 02/16/18 04:07:56 PM
#141267   “Fluvoxamine (SSRI) 17.0 F1ash 02/16/18 09:14:19 AM
#140595   I did have faith, for 2years. Don't like CashMoney75 02/11/18 12:11:09 PM
#141363  Sticky Note DD re: discussion of genome sequencing database: This is Biostockclub 02/16/18 04:07:56 PM
#139203  Sticky Note Adaptive Trial Design - what is it and Investor2014 01/31/18 05:40:05 AM
#137176  Sticky Note Flash if you’ve questions and concerns about our polarbear77 01/12/18 11:19:13 AM
#135567  Sticky Note Good lessons learned from AVXL investment in 2017. Rising_Sun 12/29/17 02:53:39 AM
#129044  Sticky Note People seem to always lose track of the dadofmarcmax 11/06/17 10:58:33 AM
#141730   I don't really like to interrupt the nice makemydaze 02/19/18 07:14:12 PM
#141729   Mods should not be breaking tos as often scottsmith 02/19/18 07:13:13 PM
#141728   I thought we were all comfortable that AD sumbuysumsell 02/19/18 07:01:05 PM
#141727   That post was a "no brainer" in a XenaLives 02/19/18 06:46:19 PM
#141726   I wonder what sort of biomarker is used XenaLives 02/19/18 06:44:05 PM
#141725   Seems we can agree to disagree. I've modified sumbuysumsell 02/19/18 06:40:24 PM
#141724   AVXl BOD spends time reading IHUB to get kund 02/19/18 06:36:43 PM
#141723   REPOST - XenaLives 02/19/18 06:35:28 PM
#141722   Ask NIH if they agree with you. In LakeshoreLeo1953 02/19/18 06:33:25 PM
#141721   Read the definition PLEASE......... LakeshoreLeo1953 02/19/18 06:30:33 PM
#141720   Keep it together frrol 02/19/18 06:29:05 PM
#141719   It seems from your definition as “a characteristic sumbuysumsell 02/19/18 06:19:10 PM
#141718   It wasn't challenged because it was a correct statement... XenaLives 02/19/18 06:16:17 PM
#141717   Could the 500 extra participants in the biogen whippinsaw 02/19/18 06:10:43 PM
#141716   Not the case I am making. Responding to LakeshoreLeo1953 02/19/18 06:08:20 PM
#141715   The true knowledge for alzheimers/biomarkers/genetics/precision medicine doesn’t scottsmith 02/19/18 06:05:58 PM
#141714   I am a LOT MORE comfortable with the LakeshoreLeo1953 02/19/18 06:02:38 PM
#141712   You should make your own definitions...they will be ExtremelyBullishZig 02/19/18 05:31:24 PM
#141711   You have been spot on since the beginning. ExtremelyBullishZig 02/19/18 05:29:10 PM
#141710   Bios, my pleasure. You bring insight and knowledge nidan7500 02/19/18 05:11:14 PM
#141709   So you are saying that it isn't true Steady_T 02/19/18 04:39:40 PM
#141708   Alzheimer's Guidance and other news about Biogen and Talon38 02/19/18 04:39:19 PM
#141707   Thanks, Nidan. Does it appear to you that the Biostockclub 02/19/18 04:33:22 PM
#141706   Bio...thanks for this article. nidan7500 02/19/18 04:30:26 PM
#141705   BP missed the alz boat. Drunk on amyloid. Bourbon_on_my_cornflakes 02/19/18 04:11:42 PM
#141704   Thanks, Bourbon! You get it. Missling gets it. AVXL Biostockclub 02/19/18 04:10:52 PM
#141703   Penny wrote..Retail was too early to party MM nidan7500 02/19/18 04:06:23 PM
#141702   I take it you are of the opinion LakeshoreLeo1953 02/19/18 03:59:15 PM
#141701   And everyone wonders why we are manipulated!!! Retail Penny Double 02/19/18 03:40:10 PM
#141700   Power, Your assumptions are as good as Talon38 02/19/18 03:38:22 PM
#141699   "the tip of the iceberg" [Illumina] Bourbon_on_my_cornflakes 02/19/18 03:16:10 PM
#141698   I will take your word for it. ohsaycanyousee82 02/19/18 03:10:41 PM
#141697   Bourbon--"$500 share would make my retirement"---IMO--very doable--when all plexrec 02/19/18 03:01:59 PM
#141696   Thanks for the laugh! That's the most XenaLives 02/19/18 02:50:02 PM
#141695   No doubt your posts fill the SAB and Investor2014 02/19/18 02:49:09 PM
#141694   The $20 billion value of an alz drug Bourbon_on_my_cornflakes 02/19/18 02:44:01 PM
#141693   SAB member of AVXl cite IHUB post, this kund 02/19/18 02:41:05 PM
#141692   Chuzzlewit, by chance do you have any patients powerwalker 02/19/18 01:50:08 PM
#141691   "Playing the piano again!" SirCharChar 02/19/18 01:46:08 PM
#141690   Bullet, people don't like taking pills and if powerwalker 02/19/18 01:33:39 PM
#141689   Just another piece of cheese.... Mikesc 02/19/18 01:26:56 PM
#141688   Why has there not been greater news coverage nidan7500 02/19/18 01:14:57 PM
#141687   Compliance With Real Drugs Always A Problem falconer66a 02/19/18 01:10:47 PM
#141686   60 minute special about alzheimer's on CBS was whippinsaw 02/19/18 12:55:01 PM
#141685   Obviously, you would stop because of the great Investor2014 02/19/18 12:39:01 PM
#141684   We've been here before. baltimorebullet 02/19/18 12:27:29 PM
#141683   SBSS, good idea since iHub tracks followers, why powerwalker 02/19/18 12:18:37 PM
#141682   It was a safety test.. Pass McMagyar 02/19/18 12:11:43 PM
#141681   ... and for the secrecy of its findings. powerwalker 02/19/18 11:59:38 AM
#141680   Another red herring argument... XenaLives 02/19/18 11:58:20 AM