Anavex Life Sciences Corp (AVXL) Company website: http://www.anavex.com/
Nasdaq Company Address: 51 West 52nd Street, 7th floor
New York, NY
1-844-689-3939 CIK: 0001314052
Anavex®Life Sciences Corp. (the “Company”) is a clinical stage biopharmaceutical company engaged in the development of differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental diseases including drug candidates to treat Alzheimer’s disease, other central nervous system (“CNS”) diseases, pain and various types of cancer. The Company’s lead compound ANAVEX®2-73 is being developed to treat Alzheimer’s disease, Parkinson’s disease and potentially other central nervous system diseases, including rare diseases, such as Rett syndrome.
Anavex®Life Sciences’ lead drug candidate, ANAVEX®2-73, recently completed successfully a Phase 2a clinical trial for Alzheimer’s disease. ANAVEX®2-73 is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors. Preclinical studies demonstrated its potential to halt and/or reverse the course of Alzheimer’s disease. It has also exhibited anticonvulsant, anti-amnesic, neuroprotective and anti-depressant properties in animal models, indicating its potential to treat additional CNS disorders, including epilepsy and others. The Michael J. Fox Foundation for Parkinson’s Research has awarded Anavex® a research grant to develop ANAVEX®2-73 for the treatment of Parkinson’s disease to fully fund a preclinical study, which could justify moving ANAVEX®2-73 into a Parkinson’s disease clinical trial. ANAVEX®3-71, also targeting sigma-1 and M1 muscarinic receptors, is a promising preclinical drug candidate demonstrating disease modifications against the major Alzheimer’s hallmarks in transgenic (3xTg-AD) mice, including cognitive deficits, amyloid and tau pathologies, and also with beneficial effects on neuroinflammation and mitochondrial dysfunctions.
The Company is in preparation for ANAVEX®2-73 for a Phase 2/3, placebo-controlled trial in Alzheimer’s disease as well as a Phase 2, placebo-controlled trial in Rett syndrome, for which the U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation (ODD) for ANAVEX®2-73 and a Phase 2, placebo-controlled trial in Parkinson’s disease.
Headquartered in New York, Anavex® Life Sciences is an American publicly traded corporation on Nasdaq quoted as AVXL . Management: https://www.anavex.com/our-team/ Pipeline: https://www.anavex.com/pipeline/
Patent Info: https://www.anavex.com/?s=patents Clinical Trials: https://clinicaltrials.gov/ct2/results?term=Anavex+Life+Sciences&Search=Search Recent News: https://finance.yahoo.com/q?s=avxl&ql=1 Company News Releases: http://anavex.com/news/ Filings: https://www.sec.gov/cgi-bin/browse-edgar?company=anavex&owner=exclude&action=getcompany Share Structure: See SEC filings Investor Relations: firstname.lastname@example.org Marketing Details: https://www.anavex.com/investor-material/events/ All messages, including iBox content, are the opinion of the posters, are no substitute for your own research, and should not be relied upon for stock trading or any other purpose. Also, keep in mind that moderators may or may not have a position in said stock. Being a moderator isn’t a sign of endorsement. Please keep your posts on topic because your message(s) will probably be deleted when:
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