Yes, we'll spotted. 👍️

#dcvax #allsolidtumors $nwbo #gbm #TissueAgnostic #PrecisionMedicine

UK has a terrible record for brain cancer survival (22/29), the submission for approval of DCVAX®-L could not come at a better time.https://t.co/k9FcN2nnNQ pic.twitter.com/KeKpII6RM6

— Peter Davis (@peter_brit) January 27, 2024

#dcvax #allsolidtumors $nwbo #gbm #TissueAgnostic #PrecisionMedicine

“ILAP enabled regular and open dialogue with NICE which was crucial in ensuring patients were able to access this medicine as early as possible.”https://t.co/PuPzJBFXoH pic.twitter.com/UwMHy60Pd1

— Peter Davis (@peter_brit) January 27, 2024

#dcvax #allsolidtumors $nwbo #gbm #TissueAgnostic #PrecisionMedicine

Curious About Cancer Care? These Are Breakthroughs and Trends in Immunotherapy
January 18, 2024

Cancer immunotherapy is the most innovative and forward-thinking form of cancer treatment available to patients… pic.twitter.com/T0NcpDPbIO

— Peter Davis (@peter_brit) January 27, 2024

#dcvax #allsolidtumors $nwbo #gbm #TissueAgnostic #PrecisionMedicine https://t.co/cdLvBLbsDZ pic.twitter.com/OWsHl4oXOs

— Peter Davis (@peter_brit) January 27, 2024

#dcvax #allsolidtumors $nwbo #gbm #TissueAgnostic #PrecisionMedicine

For years, brain tumours have remained notoriously difficult to diagnose. They affect hundreds of thousands of people worldwide each year, and kill more children and adults under the age of 40 in the UK than… pic.twitter.com/Dfk54PAJOG

— Peter Davis (@peter_brit) January 26, 2024

#dcvax #allsolidtumors $nwbo #gbm #TissueAgnostic #PrecisionMedicine

11th Neuro-Oncology Brain Tumor Symposium 2024

Friday, January 26, 2024
CME/CNE-accredited
patient & caregiver program
7:30 am - 4:00 pm EST

Progress in “The War on Cancer” Innovation and Scientific… pic.twitter.com/4ltqoUb72t

— Peter Davis (@peter_brit) January 25, 2024

Anybody have full access ?

#dcvax #allsolidtumors $nwbo #gbm

Impact of tissue-agnostic approvals on management of primary brain tumors

Tissue-agnostic approvals, based on basket trials of multiple tumor histology, permit biomarker-driven targeting of specific shared molecular alterations, regardless of… https://t.co/CfqRoXNJj6

— Peter Davis (@peter_brit) January 20, 2024

#dcvax #allsolidtumors $nwbo #gbm

Another lovely story of a long-term DCVax® survivor. Nigel French was diagnosed in 2015.

One patient in the 331-person multicentre global study lived for more than eight years after receiving DCVax. In Britain, 53-year-old Nigel French is… pic.twitter.com/z3mH4GI9WX

— Peter Davis (@peter_brit) January 18, 2024

"It’s going to be critical for mRNA type treatments"

These approaches however, are certainly not limited to use with mRNA type treatments, This could improve the efficacy and safety of DCVax and other personalized cancer vaccines. The article does give the following examples:-

"More recently, personalized vaccinations in the form of mRNA, peptides, or peptide-loaded antigen presenting cells (APCs) have been shown to be safe, immunogenic and capable of generating durable clinical response"

However, he article author's statement:-

"Cutting edge approaches, that leverage the computational tools and machine learning algorithms, have been developed recently offering new possibilities for understanding immune responses and developing personalized immunotherapies. Overall, these innovative tools, in combination with experimental data, pave the way for more effective and tailored immunotherapeutic approaches, offering valuable insights for personalized immunotherapies"

is just as relevant for DCVax and other personalzed immunotherapies as it is for mRNA treatments.

Introducing: The first-ever GLIOBLASTOMA SUMMIT.

Join us in Miami, FL on November 1-3, 2024 at Sacred Space Miami for 3 days of connecting with the glioblastoma community.

For inquiries email us at contact@gbmresearch.org pic.twitter.com/zhrUbwR5dm

— Glioblastoma Research Organization (@glioblastomaorg) January 16, 2024

#dcvax #allsolidtumors $nwbo #gbm @glioblastomaorg

So sad.

On 21st December 2023. Northwest Biotherapeutics submitted a Marketing Authorization Application in the UK for DCVax®-L. Northwest Biotherapeutics personalized cancer vaccine treats both newly-diagnosed and recurrent… pic.twitter.com/xpp4JLV91L

— Peter Davis (@peter_brit) January 18, 2024

#dcvax #allsolidtumors $nwbo #gbm

Utilizing immunogenomic approaches to prioritize targetable neoantigens for personalized cancer immunotherapy
2023 Dec 12.

"Cutting edge approaches, that leverage the computational tools and machine learning algorithms, have been developed… pic.twitter.com/RLmHZTBKzk

— Peter Davis (@peter_brit) January 18, 2024

#dcvax #allsolidtumors $nwbo #gbm

Historical perspective and future directions: computational science in immuno-oncology
First published January 8, 2024.

"Additional immuno-oncology approaches, including adoptive cell transfer (ACT) therapies and cancer vaccines, also hold…

— Peter Davis (@peter_brit) January 18, 2024

Of the hundreds of interesting topics that the NCI could discuss, this is what it chooses to learn more about virtually every week… think about it. $NWBO https://t.co/c1xfbfwxIi

— Bio99 (@BIO99_BIO99) January 17, 2024

#dcvax #allsolidtumors $nwbo #gbm https://t.co/M9mkQhhgnx

— Peter Davis (@peter_brit) January 17, 2024

#dcvax #allsolidtumors $nwbo #gbm @ImmortaBio

"Many times we dont think of cells in their in vivo context …here is finding that sheer stress induces DC activation. $nwbo are leading the clinical implementation of dendritic cells" https://t.co/Jse4ZiXk4R pic.twitter.com/aAII6xFToR

— Peter Davis (@peter_brit) January 17, 2024

#dcvax #allsolidtumors $nwbo #gbm @ImmortaBio

"Liver X Receptor (LXR) blocks dendritic cell maturation…if you want to supercharge $nwbo DC silence LXR" https://t.co/VNVojp7Gls pic.twitter.com/mufT7gcq3r

— Peter Davis (@peter_brit) January 17, 2024

#dcvax #allsolidtumors $nwbo #gbm https://t.co/TxAmtkzbNw

— Peter Davis (@peter_brit) January 18, 2024

#dcvax #allsolidtumors $nwbo #gbm

A Cancer Journal for Clinicians
ARTICLE

Cancer statistics, 2024https://t.co/KLFm7Cosxf pic.twitter.com/EVNv7muBI2

— Peter Davis (@peter_brit) January 18, 2024

#dcvax #allsolidtumors $nwbo #gbm https://t.co/SxDHmkeDkJ

— Peter Davis (@peter_brit) January 18, 2024

#dcvax #allsolidtumors $nwbo #gbm

Please help us to extend Danielle’s life

DCVax-L is a type of immunotherapy known as a dendritic cell vaccine. Developed by Northwest Biotherapeutics DCVax-L is a personalised vaccine made from each patient’s own dendritic cells – a type of… pic.twitter.com/2NBfSXK3Oz

— Peter Davis (@peter_brit) January 17, 2024

#dcvax #allsolidtumors $nwbo #gbm

Experts Forecast 2024, Part 1: Advances in Cancer Vaccines

January 8, 2024 by Neha J. Pancholi, PhD
2024 is here, and there is so much on the year’s agenda—a total solar eclipse over parts of North America; the Summer Olympics in Paris; the… pic.twitter.com/ZaO3cPFIlU

— Peter Davis (@peter_brit) January 17, 2024

#dcvax #allsolidtumors $nwbo #gbm

Advancements in dendritic cell vaccination: enhancing efficacy and optimizing combinatorial strategies for the treatment of glioblastoma
31 October 2023

"Recently, in 2023, Liau et al. revealed the results from a large Phase III trial… pic.twitter.com/vVsPx65Ucn

— Peter Davis (@peter_brit) January 17, 2024

#dcvax #allsolidtumors $nwbo #gbm

Dendritic cell therapy for neurospoagioma: Immunomodulation mediated by tumor vaccine

Published: 06 January 2024

"In a recent Phase 3 prospective externally controlled non-randomized trial, the overall survival rate (OS) of GBM patients who… pic.twitter.com/PgFsP8TMzl

— Peter Davis (@peter_brit) January 17, 2024

#dcvax #allsolidtumors $nwbo #gbm

Glioblastoma Immunotherapy: New Hope in Brain Cancer Treatment
January 16, 2024

"Despite surgery, radiation and chemotherapy, recurrence remains almost inevitable without additional interventions combatting microscopic glioblastoma foci.… https://t.co/okoaVTOEZ8

— Peter Davis (@peter_brit) January 17, 2024

Thanks to the October 2023 published CBTRUS Statistical Report: Primary Brain and Other Central Nervous System (CNS) Tumors Diagnosed in the United States in 2016-2020, we’re staying current on CNS tumor trends.

Source: Neuro-Oncology, https://t.co/0Yg6rx9rEN pic.twitter.com/MnTaxCjelK

— Glioblastoma Research Organization (@glioblastomaorg) January 16, 2024

#dcvax #allsolidtumors $nwbo #gbm https://t.co/fjSTR4KM4M

— Peter Davis (@peter_brit) January 17, 2024

https://twitter.com/peter_brit/status/1747478331753185420

#dcvax #allsolidtumors $nwbo #gbm https://t.co/OXcf2YVBAR

— Peter Davis (@peter_brit) January 17, 2024

#dcvax #allsolidtumors $nwbo #gbm https://t.co/8XP3BSYuq6

— Peter Davis (@peter_brit) January 17, 2024

#dcvax #allsolidtumors $nwbo #gbm

WEBINAR ALERT
Fit-for-purpose matchmaking: A data selection and RWE approach for both regulatory and HTA audiences
February 15, 2024 – 10AM EST; 3PM GMT; 4PM CET

This webinar will review considerations for the design and data selection for… pic.twitter.com/eAMjqLaZOM

— Peter Davis (@peter_brit) January 16, 2024

#dcvax #allsolidtumors $nwbo #gbm

Yup...suppression of COX2 in dendritic cells makes them work better in stimulating immunity.... Go $NWBO !! https://t.co/c5ZxCO30ZF

— Peter Davis (@peter_brit) January 16, 2024

#dcvax #allsolidtumors $nwbo #gbm

COX2 is increased in kidney cancer....wonder if this is a way in which it escapes from immune attack. Could COX2 inhibitors make dendritic cells like $NWBO work better? I mean they already work amazing https://t.co/gxPkv5zSl0

— Peter Davis (@peter_brit) January 16, 2024

#dcvax #allsolidtumors $nwbo #gbm

wow ! long noncoding RNA acting as tumor suppressor....very interesting how many diverse approaches the body uses to protect itself against #Cancer $NWBO is has generated the best #cancer killing sword to date...now we need to learn how to… https://t.co/hZnflJtcag

— Peter Davis (@peter_brit) January 16, 2024

#dcvax #allsolidtumors $nwbo #gbm

Dont take oxytocin if you are taking dendritic cells.... this paper shows that the "love hormone" suppresses dendritic cell maturation....this could be a neat way of taking the $NWBO dendritic cells and flipping them for use im #autoimmunity. https://t.co/MPJwMO8s57

— Peter Davis (@peter_brit) January 16, 2024

#dcvax #allsolidtumors $nwbo #gbm https://t.co/wweVzQ0r1a

— Peter Davis (@peter_brit) January 16, 2024

#dcvax #allsolidtumors $nwbo #gbm https://t.co/dP43vGL1AN

— Peter Davis (@peter_brit) January 16, 2024

In Magistrate Judge Stein's defense, I would add that Posner could have been more specific with her cite to the Milgrom Report in the Amended Complaint. She cited to where you could find the expert report but it was a docket that included hundreds of entries. See Image 1. In the… pic.twitter.com/YRmuJ8bDFB

— hoffmann6383 (@hoffmann6383) January 15, 2024

I might be wrong but thought it was a holiday day in US today for OTC markets ?