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MarketEdge has had it under accumulation for over 2 months. We’ll see if it lasts.
Survived another day!
Chicken or egg?
“High blood pressure is one of the major causes of chronic kidney disease. And kidney disease can also cause high blood pressure. No matter which came first, having high blood pressure damages the tiny blood vessels in the kidneys.”
Hopefully he has a kidney doc in addition to cardiologist.
My cousin’s kidneys were destroyed by scleroderma. Ambulance level BP was a symptom. Lupus can also attack kidneys.
Generally, most drugs other than antibiotics and a few others don’t cure anything. Vascepa seems to have some curative effects because in going after inflammation, it more addresses root cause. After being on Vascepa for a few years, I’ve gotten off most of my BP meds and now mostly under 100.
Several commercials on Jardiance every evening. Lengthy discourse on side effects. Sounds fun!
“Frequent urination, dizziness, or lightheadedness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: signs of a urinary tract infection (such as burning/painful/frequent/urgent urination, pink/bloody urine), signs of kidney problems (such as change in the amount of urine).
Get medical help right away if you have any very serious side effects, including: unusual tiredness, nausea/vomiting, stomach/abdominal pain, trouble breathing.
This medication may cause a new yeast infection in the vagina or the penis. It may also cause a rare but very serious bacterial infection in the genital/anal area (Fournier's gangrene) in people with type 2 diabetes. Tell your doctor right away if you have signs of a yeast infection in the vagina (such as unusual vaginal discharge/burning/itching/odor) or in the penis (such as redness/itching/swelling of the penis, unusual discharge from the penis). However, get medical help right away if you have any pain/redness/swelling in or around the genital/anal area, along with a fever or feeling unwell.
This medication may increase the risk of lower limb amputation (especially of the toe and foot). The risk is higher if you have poor blood flow in the legs, nerve problems, foot ulcers, or have had a previous amputation. To lessen the risk, check your feet regularly and tell your doctor if you have new pain, tenderness, sores, or ulcers on your legs or feet.
This medication may cause you to become dehydrated. This can lead to serious kidney damage. Drink plenty of fluids to prevent dehydration. Tell your doctor or pharmacist right away if you are not able to drink fluids as usual, or losing fluid (such as due to vomiting, diarrhea, or heavy sweating). Also, tell your doctor right away if you have any signs of dehydration, such as urinating less than usual, unusual dry mouth/thirst, fast heartbeat, or dizziness/lightheadedness/fainting.”
Fortunately I didn’t get in until 2013. The poor blokes in before likely got slaughtered as will we current SH’s if there is another RS.
A company that recovered from a RS is more rare than a two-horned albino unicorn.
I guess there would be one vote.
As of yesterday, MarketEdge had support at $0.60-$0.61. Resistance only slightly higher at $0.62-$0.63. B Bands at 11 so could change sharply if perturbed by news.
Looks like it (again). FFS probably should have set his lower.
https://www.medscape.com/viewarticle/976490?form=fpf
Also, Kiwi is an admirer of Ridker so he might be able to find something.
So you consider this mealy mouthed piece of bafflegab of a conclusion to be worthy of someone aspiring to be a respected researcher?
Among participants in REDUCE-IT, allocation to icosapent ethyl had minimal effects on a series of biomarkers associated with atherosclerotic disease, whereas levels increased among those allocated to mineral oil. The effect of these findings on interpretation of the overall risk reductions in clinical events observed within REDUCE-IT is uncertain.
There’s this ridiculous paper by Ridker. How Bhatt and other “Men of Science” people put their name on it is beyond me.
https://pubmed.ncbi.nlm.nih.gov/35762321/
I didn’t see any specific treatments. Nor in this CNN article.
https://www.cnn.com/2024/08/31/health/blood-biomarkers-women-heart-disease-risks/index.html
Two people from your men of conjecture(?) in this article. Huge progress though, Lp(a) now being promoted as a biomarker for CVD. Wonder how long before sdLDL-c comes to their attention?
https://www.nbcnews.com/health/heart-health/simple-blood-test-predict-persons-heart-disease-risk-30-years-study-fi-rcna169009
Some good links here.
https://deniseminger.com/the-china-study/
The book:
“Death by Food Pyramid, How Shoddy Science, Sketchy Politics and Shady Special Interests Ruined Your Health…and How to Reclaim It” by Denise Minger
is informative and discusses crappy research by Acel Keys and others.
What does a septuple bottom mean?
My bmi is 21.5. If I were deciding, starting age for CAC scan would be same as for colonoscopy, 45. It is noninvasive, low radiation dose and inexpensive. For economic reasons, the interventional cardiology cartel threw shade on it when first introduced, very similar to Nissan/Vascepa. “The Widowmaker” documentary is worth a watch. Many years later, these scans are becoming more accepted.
Don’t know bmi exactly, but pretty high, maybe 36. Also T2DM. He had an angiogram maybe 6-8 years earlier and no significant blockage. Plaque must have accumulated quickly so maybe not a lot of calcification in that time. This time they first did a CT angiogram (using a dye) which showed enough concern to do an angiogram.
Reliance on a single figure of merit is dangerous. Heart disease is complex and despite all the research and smart minds, continues to be the leading cause of death.
In addition to the standard cholesterol stuff, look at oxidized LDL, small particle LDL, LDL particles, LDL size, Large VLDL particles, VLDL size, Lp(a), hs-CRP, Lp-PLA2, and do a CAC scan, etc.
My brother is a classic case of the selectively compare-out community. In his case, normal blood pressure. High trigs, treated with fenofibrate but other lipids ok. Felt some discomfort while hunting. Six 90% blockages. Again, normal BP.
The disgusting socialists in North Dakota prohibit chain pharmacies and to an extent have their foot on the neck of PBM’s.
https://ilsr.org/wp-content/uploads/2014/10/ND_Pharmacy_Ownership_Report.pdf
https://www.uspharmacist.com/article/north-dakota-pharmacy-ownership-law-upheld
https://www.reuters.com/legal/transactional/8th-circ-upholds-n-dakota-rules-pharmacy-benefit-managers-2021-11-17/
Speculation on my part, but logical nonetheless.
1) Collaboration, partnership with VA & UW Madison to help fund an Alzheimer’s study based on hypothesis generating BRAVE-EPA trial.
2) Open label, no placebo, due to unethical aspects of blinded trial in this case.
3) Lymph releasing version of drug as primary for 3/4 of cohort,
Vascepa for balance.
4) Updates every 6 months, trial halted for efficacy if merited.
5) Patients with no symptoms, symptoms, with and without APOE4 gene.
6) Multiple VA centers involved.
Pretty typical after post earnings slump. Volume suggests may be more to it this time.
Another Amarin earnings report. Deja vue all over again and entertaining for sure.
1) Run up/accumulation into earnings.
2) Results not terrible, some good news, some bad.
3) pps sags
4) FFS goes full blow-hard
5) Kiwi beats his dead, now decaying, maggot infested, horse calling for confirmatory trials for an already proven drug.
6) dmiller, GLOAT (Greatest Loser Of All Time), does his thing.
7) JRoon71 disappears.
8) Many posts deriding Sarissa, current management, past management, BOD past and present.
Can’t make this stuff up.
Check out WPRT. They did a 10:1 reverse split June 2023. You might want to let professionals handle your investments.
Check out WPRT. They did a 10:1 RS in June last year. Feel free to predict when sp will get to $20, my basis before I abandoned it.
The purpose of a RS is to screw the current stockholders while creating an opportunity for new investors.
Statinistas arguing over how many heart attack victims can dance on the head of a pin while ignoring the elephant in the room.
https://www.statnews.com/2024/07/29/cardiovascular-risk-model-statins-heart-attacks/
Careers will be made and sidelined in Alzheimer’s research to say nothing of the financial aspects. The stakes are enormous. For some reason UW and VA is taking their time with this.
Well, one way to look at it is they wanted to get questions about adverse effects dealt with and out of the way because results, based analysis to date, is expected to be positive.
Regardless of outcome results, positive, negative, or neutral, why leave them out. Could it be because their statement that analysis of drug study efficacy are still ongoing is in fact true?
If null, as you say, why go to the trouble of a presentation to point out no adverse effects relative to the placebo?
https://eppro01.ativ.me/src/EventPilot/php/express/web/planner.php?id=AAICLITE24
Impact of Icosapent Ethyl on Lipids, Blood Pressures, and Adverse Events in Cognitively Healthy Veterans Participating in the BRAVE Study
8:00am-4:15pm Jul 28 (Eastern)
Cecilia Cardenas, Carol Van Hulle, Hannah Zylstra, Kate Cronin, Aleshia Cole, Elena Bec…
About time. Hope others get indicted as well.
https://www.wsj.com/finance/stocks/u-s-accuses-prominent-short-seller-andrew-left-of-fraud-0161e42f
The article doesn’t state his LDL or trigs, but with a CAC score of 530 and BP of 160/90, he’s a walking dead man. More than anything, the article illustrates how heart disease patients are poorly served by medical professionals. They have one arrow in their quiver, lower LDL. Maybe triglycerides.
My point wasn’t about statin intolerance, it was that Vascepa wasn’t even mentioned.
Then there’s Dr Keith.
Patient seeks an option to statins
Keith Roach, M.D. Updated: July 22, 2024
Q: I had a CT calcium scan, and my score was 530. My doctor said that this was high, so he put me on a statin (Lipitor). But it debilitated me with so much muscle pain that I had to stop. I am wondering if there is something other than a statin to help lower cholesterol. My doctor told me to go on the Mediterranean-style diet, then check my numbers again. Last time, my blood pressure was 160/90 mm Hg. I also have a family history of heart disease.
A: I entered your information into a calculator (the MESA score, available at tinyurl.com/MESAscore) and found that you have an approximately 13% risk of having a heart attack, needing a bypass, or dying from heart disease in the next 10 years. This is high enough that treatment to reduce risk is clearly recommended. A statin like Lipitor is usually the first-line treatment, since we have decades of research showing that it reduces heart attack in people at a high risk. Treatment with a statin is expected to reduce your risk to about 10.5%. A Mediterranean-style diet is expected to reduce your risk by another 1% or 2%.
When a person can’t tolerate Lipitor, I usually stop the drug for at least a month, then restart them on a different statin, preferably one with a lower risk of muscle pain. If a person really can’t tolerate any statin, then another option is the new treatment bempedoic acid, which works similarly to a statin but does not affect muscles. Unfortunately, it’s very expensive. Some other options are a PCSK-9 inhibitor, which is also very expensive, or ezetimibe, which isn’t quite as effective, but is better than no treatment at all.
Getting your blood pressure down (ideally below 130 mm Hg) either through lifestyle changes or medication can also reduce your heart disease risk.
MarketEdge: Showing slight improvement. As of today, Amarin is under accumulation. B Bands=17, Under 20 means volatility has contracted so there could be a sharp movement (either way).
As of 07/15/2024 - Avoid the stock.
Stock is Not a Short Sale Candidate.
If you are Long; close position or monitor stock closely.
On 07/15/2024, The stock is underperforming the market over the last 50 trading days when compared to the S&P 500. The MACD-LT, an intermediate-term trend indicator, is bullish at this time. A close above $1.28 is a number to watch to confirm a trend reversal.Momentum as measured by the 9-day RSI is positive but showing signs of slowing. Over the last 50 trading sessions, there has been more volume on up days than on down days, indicating that AMRN is under accumulation, which is a bullish condition. The stock is trading below a falling 50-day moving average. A close above this moving average would be supportive of the improving conditions.
This guy, Rick Scott?
On March 19, 1997, investigators from the Federal Bureau of Investigation, the Internal Revenue Service, and the Department of Health and Human Services served search warrants at Columbia/HCA facilities in El Paso and on dozens of doctors with suspected ties to the company.[31] Eight days after the initial raid, Scott signed his last SEC report as a hospital executive. Four months later, the board of directors pressured him to resign as chairman and CEO.[32] He was succeeded by Thomas F. Frist Jr.[33] Scott was paid $9.88 million in a settlement, and left owning 10 million shares of stock then worth more than $350 million.[34][35][36] The directors had been warned in the company's annual public reports to stockholders that incentives Columbia/HCA offered doctors could run afoul of a federal anti-kickback law passed in order to limit or eliminate instances of conflicts of interest in Medicare and Medicaid.[33]
During Scott's 2000 deposition, he pleaded the Fifth Amendment 75 times.[37] In settlements reached in 2000 and 2002, Columbia/HCA pleaded guilty to 14 felonies and agreed to a $600+ million fine in what was at the time the largest health care fraud settlement in U.S. history. Columbia/HCA admitted systematically overcharging the government by claiming marketing costs as reimbursable, by striking illegal deals with home care agencies, and by filing false data about use of hospital space. It also admitted to fraudulently billing Medicare and other health programs by inflating the seriousness of diagnoses and to giving doctors partnerships in company hospitals as a kickback for the doctors referring patients to HCA. It filed false cost reports, fraudulently billed Medicare for home health care workers, and paid kickbacks in the sale of home health agencies and to doctors to refer patients. In addition, it gave doctors "loans" never intending to be repaid, free rent, free office furniture, and free drugs from hospital pharmacies.[38][7]
In late 2002, HCA agreed to pay the United States government $631 million, plus interest, and $17.5 million to state Medicaid agencies, in addition to $250 million paid up to that point to resolve outstanding Medicare expense claims.[39] In all, civil lawsuits cost HCA more than $2 billion to settle; at the time, this was the largest fraud settlement in U.S. history.[40][41]