Tyme Technologies Inc. (TYME)

[ChillingPenguin]

Finally some good news, let's go TYME!!

[murocman]

Why? There aren’t any earnings nor will there be for some time.

Murocman

[herbied47]

This will spike come earnings.

[mcsharkey]

From the annual report in prep of the annual August shareholders proxy vote:
Notable Developments in Fiscal 2021 and Subsequent:

• 6/20 New preclinical data supporting SM-88 mechanism presented at AACR
• 6/20 Preclinical data demonstrating anti-cancer effect of TYME-18 presented at AACR
• 8/20 SM-88 granted Orphan Drug Designation from FDA for potential treatment of patients with pancreatic cancer
• 8/20 Outcome of interim futility review for HopES sarcoma Phase 2 study announced
• 8/20 TYME-19 announced as potential treatment for COVID-19
• 9/20 Phase 2 prostate cancer study published in the Journal Investigation New Drugs
*********************
• 11/20 Richie Cunningham appointed as Chief Executive Officer
• 2/21 Completed $100 million Registered Direct Offering
*********************
FY 22
• 4/21 Dr. Jan M. Van Tornout appointed as acting Chief Medical Officer
• 5/21 Frank L. Porfido appointed as Chief Financial Officer, effective June 2021

The quick turnaround from November 2020 --> February 21
.....with Rich Cunningham put in CEO seat and then the
.....$100 Million funding finally completed, the investors on
.....the funding had Cunningham hand-picked
....well before the buy-in.

May be the reason for Hoffman (founder) stepping down. Hoffman was very visible in June 10th telecon. Honestly, disappointed in the proxy sample ballot being limited to standard auditing company, couple other items of no real impact like voting on a buyout (sigh) or a reverse split (whew).

Neither in the cards at this time. Here's an excerpt from Cunningham's statement early on in the annual report:
*******************************
I can say with a high degree of confidence that TYME is positioned to capitalize on the significant opportunities before it and create significant value for our stakeholders.

I deeply believe that our novel candidates have great potential to make a profound difference in the lives of people we aim to help in the years to come. On behalf of the entire team at TYME, I would like to thank you for your interest and support.

Richie Cunningham
Chief Executive Officer
*************************************
VR, and Good Luck to All

[mcsharkey]

Annual Meeting Notice released today on EDGAR

The following Proxy Materials are available to you to review at Company Link[/quote]

 
 • Company’s Annual Report for the year ended March 31, 2021; 
 • the Company’s 2021 Proxy Statement; the Proxy Card; and any amendments to the foregoing materials that are required to be furnished to stockholders. 
 

[/quote]Proxy ballot released today for LINK to Proxy Vote

Down Load them and we'll chit=chat
VR

[mcsharkey]

Yeah Enviro, compared to a year ago, daily volume is way up, but so are the Outstanding Shares. Not much in the short exchange.

One month+ to our Investors Annual Meeting (August). Thumbs Up/ Thumbs Up:). Sample ballot for proxy vote may hold REAL NEWS, or just for members of the board and our auditing firm ?? Sigggghhhh.

Happier with a whole NEW BOARD than those who told us the moon shot would happen SOON. FY21. We're in FY22, 2Q.

IMHO, the $100 mill buy-in boys hand-picked current board. I'm in with that.

We'll see. Supposed to expand to multiple cancers. Disappointed in halt of COVID cure. Obviously wasn't working.

All I got.
GLTY and to All (not many of us)
re

[Enviroman08]

This action is not positive ...in the short term.

[buby89]

Joeyrachwal aimt gna be happy about this… poor guy

[mcsharkey]

Happy Father's Day Chilling! Sorry for the late reply. I was disappointed in NO BREAK OUT news. Satisfied, and will tell you why later this day. My wife dragged me away. And just got back. I've looked through the damn transcript. Going to dig a little further. At first, I thought it was just a team introduction.

Give me a bit of time Handsome. I'll be back.
VR:)

[mcsharkey]

Happy Fathers' Day Frank! However it applies to you.
VR just Very Respectfully signature block. The ending of my request for info on the telecon. They never answered it evidently.

My wife got us a cruise for Father's Day, instead of the compound mitre saw I thought I wanted:)
Sorry for the delay.

Very Respectfully (VR) or /R:)
Enjoy the Day

[ChillingPenguin]

Mcsharkey what are your thoughts with today's information?

[Enviroman08]

From Gun's & Roses

You and I just use a little patience!

[Enviroman08]

I believe these are truly bargain prices for this stock...adding more.

[Frankestin]

Who are you referring to with VR?

[Frankestin]

Ok today we will see an updated business plan!
Come on Richie show us how a good boy you are!

make us dream!

[mcsharkey]

Working on Qzzz for Thursday's Q&A. Dunno. Thinking clinical trials will be covered. How bout finances?

Thank you for protecting retail holders on the S1 with the pump before hand with COVID related patent. Also appreciate setting up a protection wall to defend against hostile takeover with 6 million options reset to $1.50 with S8.

At this time, what is the feasibility of a lucrative merger with a major pharmaceutical?
VR
"""""""'"'""'"'
I like it. Need another couple. Anybody?
GLTUA

[mcsharkey]

Peace, Health and Happiness!
To You and Yours.

Apologies 'bout my crazed association of us to Harvard Medical graduation.
Link here to at least 2nd edition update of this Seeking Alpha analyst's convictio in us:

Tyme Technologies: Recent Sell-Off Provides Opportunity To Buy At A Discount
https://seekingalpha.com/article/4432043-tyme-technologies-recent-sell-off-provides-opportunity-to-buy-at-a-discount
GLTUA

[Frankestin]

;D

[Frankestin]

I t’s tyme for happy days!

[mcsharkey]

Harvard Medical School IS having an announcement this week during graduation. Here's a bit on their Proof of Concept

International COVID-19 Trial to Restart with Focus on Immune Responses

https://www.nature.com/articles/d41586-021-01090-z

We'll find out.
GLTUA

[mcsharkey]

It'd be nice to have some of those six million $1,50 shares just registered for insider purchases be struck on NOW.

NUTHIN' I can do about that.

Posted the following back around April @9th. Worth revisiting IMHO.
.
One of our collaborators Applied DNA (APDN) Sciences who we hold a Material Service Agreement (MSA) with since 2019 had a recent PR I keep on interpreting as FANTASTIC.
.
But Who TF am I?

The 2019 MSA It's the only MSA I can find for APDN. WE have a mutual research agreement for COVID therapeutics with Massachusetts General. Affiliated with Harvard School of Medicine.

Recent APDN PR that I may be reaching with. Also Harvard School of Medicine Graduation Announcement:

Press release from holding corporation of LineaRX
*******************
Master Services Agreement (MSA) with an existing customer of its Linea™ COVID-19 Assay Kit (the “Assay Kit”). The amendment doubles the undisclosed maximal value of the MSA to ensure the customer’s continuing access to the Assay Kit for the customer’s pooled COVID-19 surveillance testing program.

Concurrently, the Company announced the receipt of a purchase order for its Assay Kits and consumables to enable the customer to conduct 16,000 tests to be used for recurring surveillance testing and support the customer’s in-person graduation cerApplied DNA Secures Amendment to Master Services Agreement and Fourth Blanket Purchase Order from Linea™ COVID-19 Assay Kit Customer
Ensures Customer’s Continuing Access to Assay Kit for Pooled Surveillance Testing Program
+_+++++++++++++
greement (MSA) with an existing customer of its Linea™ COVID-19 Assay Kit (the “Assay Kit”). The amendment doubles the undisclosed maximal value of the MSA to ensure the customer’s continuing access to the Assay Kit for the customer’s pooled COVID-19 surveillance testing program.

Concurrently, the Company announced the receipt of a purchase order for its Assay Kits and consumables to enable the customer to conduct 16,000 tests to be used for recurring surveillance testing and support the customer’s in-person graduation ceremonies in May 2021.
************""*
And the Graduation Announcement from Harvard Medical School
***"""""""""""""""
Harvard Chan School Virtual Convocation Ceremony
May 27, 1 p.m.

Keynote speaker: Tedros Adhanom GhebreyesusDirector-general of the World Health Organization
***†"""""""""""
Wild guess BUT What the H
GLTUA

[mcsharkey]

Thank You, Thank You Bow!

Our recently new CEO Richie Cunningham comes across to me as a player (but Who TF am I). Wouldn't mind some of our
$1.50
Holders to start buying in. For some credibility.
VR




,

[mcsharkey]

Thanks Frank. I gotta be honest with you. I had a major high school football concussion in 1971, that manifested into a malignant cranial vascular disorder by 1995.

Several major craniotomies later I'm doing great and now retired. As for giving financial advice, I'm inically brain damaged. Really.

;) And blest. So I'll post what I think I know and let you be the judge on my opinion.

Peace be With Us All

[Frankestin]

https://meetinglibrary.asco.org/record/201597/abstract

[bowman88]

Just saw Yates on Twitter gave a mention of TYME tonight. With a following of 220k should put a few more eyeballs on the stock.

https://twitter.com/yatesinvesting/status/1395240779283587073?s=19

[bowman88]

No problem I've been lurking here for awhile and adding a lot more recently. Hope we get some sort of update which gets this going the other direction. Today was maybe a start.

I do appreciate your updates

[mcsharkey]

EXCELLENT! Thanks Bowman
Here's a dictionary for you:)

The FUTILITY term just means we are accomplishing something.

Wouldn't mind some insiders buying in at $1.50 tomorrow. Show us good faith:). Appreciate the compliment.

Thank You


Glossary of Common Site Terms - ClinicalTrials.gov

https://clinicaltrials.gov/ct2/about-studies/glossary

[bowman88]

Hey mcsharkey, appreciate your posts on here. After-hours we're going up. I saw this link on stock twits.

https://meetinglibrary.asco.org/record/201597/abstract

[mcsharkey]

Any idea how to access the abstract Frank? Much appreciated. TIA

[Frankestin]

The Publication Only abstracts are under embargo until 5:00 p.m. ET on May 19, 2021.

[mcsharkey]

IMHO, 21st of April's S-8 registration of 6 million shares with a strike price of $1.50 is our best indicator of what may be in store for us.

It comes out to approximately a $10 million funding exercise replacing previously awarded options/ warrants to insiders. Those warrants came out averaging $3.40.

More factors to consider.

Annual report must be filed no later than June. We've been told only news will come from SEC filings.

Draft level file for June presentation of Sarcoma trial should be available through ASCO (cancer society) TOMORROW. Difficult to access for layman.

On COVID. We're partnering with Massachusetts General. Harvard Medical.
.Some announcement to be held during their graduation ceremonies.

Hoping warrant holders start striking now. To me, THAT starts a moon shot.

My opinion/hope.

GLTUA
VR
mcsharkey

[dancy]

TYME

[Enviroman08]

No worries man....I find many lower priced stocks are down right now...they do not always follow the Market overall during upswings..or downswings....but I may be picking up some more shares...patience and have a good weekend.

News is key!

Your insight is much appreciated.

[mcsharkey]

Apologies for long delay Enviro. I'm hiding here. Thinking of picking up more.

Hanuman turned me on last year to a promising Alzheimer drug. We both left Casava sumthing too early. After rise from $2 to $10 then some rides around that, I pulled out moved it here:? Ahhhh. It's fluttering around $55 now.

I also did about the same with a direct competitor to us named after the healing Angel, Rafael.

They had some big buy-ins just a couple of years ago. Big backing from the Govt of Israel where they have triLs going on.

Both of us focus on screwing up cancer cell metabolism. Rafael attacks at the cell's site for glucose processing. We attack a little before that. Tyrosineis up in the MANGEMENT area of metabolism.

Both of us are in PANCAN's PRECISION Promise trials. Plenty of room for both of us.


I think we're looking good for the future, primarily in TYME-19 (COVID).

Shared this several times here. In speaking with Investor Relations, updates are going to occur through SEC filings.

Annual report now due any time (10Q)

Our collaboration for TYME-19 is Massachusettes General, Harvard Medical School. Supposed to have a formal presentation on their COVID effort at May 18 Graduation ceremony.

In cancers, we have a collaboration with Eagle Pharmaceutical. Their early March 10Q filing available on Seeking Alpha details out the contract and concerns.

Back to TYME, S8 registration for insider buys detail our business history.

IR says we will be expanding to other cancers. Pancreatic is a BEAR.

Looking myself at Harvard Graduation for NEXT NEWS.

All I got. Eagle Parma indicating we have some time till cancer trials will be reported on. So we go on

Peace

[mcsharkey]

Apologies for long delay Enviro. I'm hiding here. Thinking of picking up more.

Hanuman turned me on last year to a promising Alzheimer drug. We both left Casava sumthing too early. After rise from $2 to $10 then some rides around that, I pulled out moved it here:? Ahhhh. It's fluttering around $55 now.

I also did about the same with a direct competitor to us named after the healing Angel, Rafael.

They had some big buy-ins just a couple of years ago. Big backing from the Govt of Israel where they have triLs going on.

Both of us focus on screwing up cancer cell metabolism. Rafael attacks at the cell's site for glucose processing. We attack a little before that. Tyrosineis up in the MANGEMENT area of metabolism.

Both of us are in PANCAN's PRECISION Promise trials. Plenty of room for both of us.


I think we're looking good for the future, primarily in TYME-19 (COVID).

Shared this several times here. In speaking with Investor Relations, updates are going to occur through SEC filings.

Annual report now due any time (10Q)

Our collaboration for TYME-19 is Massachusettes General, Harvard Medical School. Supposed to have a formal presentation on their COVID effort at May 18 Graduation ceremony.

In cancers, we have a collaboration with Eagle Pharmaceutical. Their early March 10Q filing available on Seeking Alpha details out the contract and concerns.

Back to TYME, S8 registration for insider buys detail our business history.

IR says we will be expanding to other cancers. Pancreatic is a BEAR.

Looking myself at Harvard Graduation for NEXT NEWS.

All I got. Eagle Parma indicating we have some time till cancer trials will be reported on. So we go on

Peace

[Enviroman08]

Patience...need a little patience....I have lost out on big money in the past due to lack of it.

[HANUMAN]

Same here. Left too soon. Back in now, but way fewer shares. Sob!

[mcsharkey]

Thinking the big guns associated early news from a collaborator of ours whose novel PCR detection system for Invasive Circulating Tumor Cells we've adopted for showing our progress monitoring SM-88's eradication of those.

Press release from holding corporation of LineaRX
*******************
Master Services Agreement (MSA) with an existing customer of its Linea™ COVID-19 Assay Kit (the “Assay Kit”). The amendment doubles the undisclosed maximal value of the MSA to ensure the customer’s continuing access to the Assay Kit for the customer’s pooled COVID-19 surveillance testing program.

Concurrently, the Company announced the receipt of a purchase order for its Assay Kits and consumables to enable the customer to conduct 16,000 tests to be used for recurring surveillance testing and support the customer’s in-person graduation ceremonies in May 2021.
************""*
Massachusetts General (our collaborator with THYME 19 for COVID) is aligned to Boston University School of Health. Graduating scheduled for May 18th.

Applied DNA Secures Amendment to Master Services Agreement and Fourth Blanket Purchase Order from Linea™ COVID-19 Assay Kit Customer
Ensures Customer’s Continuing Access to Assay Kit for Pooled Surveillance Testing Program

Here's the only other service agreement I'm aware of that APDN has

November 26, 2019
Applied DNA Sciences Subsidiary LineaRx Signs Agreement with TYME Technologies for Functional Invasive Circulating Tumor Cell Assay Services in Pancreatic Cancer Trial
Demonstrates Growing Interest and Demand for Alternatives to Plasmids as Source of DNA in Pre-Clinical Therapeutic Applications
STONY BROOK, N.Y., – Applied DNA Sciences,
+_++++++++++++++++++++

A Guess, may be REAL GREAT HERE in 3 weeks

Gotta get to APDN Board. Mick, Hanuman see you there. Hanuman, I left SAVA way too soon. Hope you Killed IT:)

[mcsharkey]

Yeah Enviro, I've started buying up small amounts now. Just blew all
my dry powder. Got more shares than a pig can $#1+

Always wanted to see a pig do that for just one share:).


At $1.33 from close and $1.50 strike price for 6 of 9 million options outstanding, we got some play time opportunity.

From the 10Q filed back in March
Options exercisable at 2020:12/31: 9,853,275
Weighted Average Exercise Price:$3.70

Last week S-8 registration to raise $10 million from insiders is going to set our PPS at $1,50 for a while once the buying starts.

Top of my head, that's a quick 14;% gain pretty quickly.

The speed of getting to $10 mill may be the ultimate signal.

Thinking the options holders have abargain basement price.

[Enviroman08]

This has the feeling of a slow bleed to the 1.00 range, hope I'm wrong...but we went through the 200 mda and I've seen this slow bleed many times...everyone thinks it can't lower then it keeps slowly bleeding.

Of course this does not take into good news or new approvals/contracts, etc.

I still feel this is a long term stock to have.

[mcsharkey]

RFI sent to new IR rep[/quote]Good Day Jon,
I'd appreciate your insight on the current S-8. This following data is extracted from the 3d Quarter's 10Q filing on 5 March at following link:

EDGAR Link[/quote]

 
 		Options exercisable at 2020:12/31: 9,853,275 
 		Weighted Average Exercise Price:$3.70

[/quote]

Does current S-8 clean the slate of these?

Second question is the time period expected for applicable option awardees to buy in the 6 million shares now registered?

There doesn't seem to be a time period listed on the S-8. At this time, retail investors have realistic concern of being anchored to the $1.50 PPS remains while the stock is effectively diluted. We had only 100,000 million O/S at the end of the 2021 third Quarter. The open time span an rock bottom PPS on it are disheartening.

All Help is Appreciated
VR [/quote]GLTUA

[mcsharkey]

RFI sent in to new IR rep. We'll see.[/quote]Good Day Jon,
I'd appreciate your insight on the current S-8. This following data is extracted from the 3d Quarter's 10Q filing on 5 March at following link:

[urlhttps://yahoo.brand.edgar-online.com/DisplayFiling.aspx?TabIndex=2&FilingID=14668459&companyid=873303&ppu=%252fdefault.aspx%253fsym%253dTYME[/url][tag]EDGAR Link[/tag][/quote]

 
 		Options exercisable at 2020:12/31: 9,853,275 
 		Weighted Average Exercise Price:$3.70

[/quote]

Does current S-8 clean the slate of these?

Second question is the time period expected for applicable option awardees to buy in the 6 million shares now registered?

There doesn't seem to be a time period listed on the S-8. At this time, retail investors have realistic concern of being anchored to the $1.50 PPS remains while the stock is effectively diluted. We had only 100,000 million O/S at the end of the 2021 third Quarter. The open time span an rock bottom PPS on it are disheartening.

All Help is Appreciated
VR [/quote]GGood Day Jon,
I'd appreciate your insight on the current S-8. This following data is extracted from the 3d Quarter's 10Q filing on 5 March at following link:

[urlhttps://yahoo.brand.edgar-online.com/DisplayFiling.aspx?TabIndex=2&FilingID=14668459&companyid=873303&ppu=%252fdefault.aspx%253fsym%253dTYME[/url][tag]EDGAR Link[/tag][/quote]

 
 		Options exercisable at 2020:12/31: 9,853,275 
 		Weighted Average Exercise Price:$3.70

[/quote]

Does current S-8 clean the slate of these?

Second question is the time period expected for applicable option awardees to buy in the 6 million shares now registered?

There doesn't seem to be a time period listed on the S-8. At this time, retail investors have realistic concern of being anchored to the $1.50 PPS remains while the stock is effectively diluted. We had only 100,000 million O/S at the end of the 2021 third Quarter. The open time span an rock bottom PPS on it are disheartening.

All Help is Appreciated
VR [/quote]GLTUA

[mcsharkey]

Bang Bang Shoot 'em up Detin neeee
Bang Bang Shoot em up to the moon
BANG BANG SHOT EM UP
1, 2-THREEEE

1,2,3,4

We're locked in at $1:50 till the 6 million shares registered for the purchase by insiders is used up.

S8 form filed after hours Thursday doesn't detail that out. However:
************"*""""""
Form S-8 Defined
Form S-8, also called a registration statement, asks for details a company must provide to the SEC if it plans to register securities earmarked for employees via the firm's benefit or incentive programs. The S-8 document is brief and easier to complete, as long as facts that disclose information about a company’s intent to register company securities tied to benefit plans are comprehensive and detailed.
https://smallbusiness.chron.com/differences-s1-s8-filing-33577.html
********"*"""""""""
Thank you Harry Neilson for your spaceman song.

This seems pretty good Enviro, all.

[mcsharkey]

Nuther thing I don't get Enviro. Our boys are shaking the trees for another $10 Million buy-in. 6 million shares for $1.5, our sticker price today.

Here's a link to EDGAR S-8. A little odd. Exibits 3 on up are 7 year old histories of forms detailing how TYME merged with another Florida Company to become TYME Technologies. MAYBE something else in the works. Dunno.

Check it out.
https://yahoo.brand.edgar-online.com/displayfilinginfo.aspx?FilingID=14872887-950-14376&type=sect&TabIndex=2&companyid=873303&ppu=%252fdefault.aspx%253fsym%253dTYME
GLTUA

[Enviroman08]

Way over my head may be an understatement...man

[mcsharkey]

Ournew Chief Science Officer, Jan (?, a male) Turnout has some kick ass credentials aligned to similar technology as SM-88.

To boot, into pediatric cancers which our HOPES Trial is all about (Exingz Sarcoma with Joseph Ahmen Foundation)


Info only may be nothing

This link to a published white paper Turnout is part of it https://pubmed.ncbi.nlm.nih.gov/27002938/

Way over my head.
GLTU

[Enviroman08]

Morning MC & always nice to have insight...thank you.

[mcsharkey]

Sorry for the late reply Enviro and Thank You. We got a couple of real players here. Me? not so much. Got slaughtered on a bio that led me here along with Pancreatic Cancer action Network.

My wife got involved about 18 years ago, and I'm in as a cold told key staffer:)

I'm thrilled to hear your business is recovering nicely. Driving through a small industrial zone and everyone had HIRING signs.

Have done a lot of 5ks, pancake breakfast and gigs in general with PANCAN.

We have a lot of associations with REl science:).

When TYME and others got pulled in for Precision Promise, I got real interested.

Going to dig around for our BAD DAY. Probably won't find anything.

GLTUA:)

[Enviroman08]

Doing well MC...thank you for the update.

I was in this stock last fall and rode one of the upswings and sold...I certainly didn't catch it all but no one ever went broke taking a profit.

I usually only trade penny stocks for short term profit in mind but TYME
intrigues me (I will be patient with this one and may add more).

Trading is a part time thing for me (when I have time)...been in and out of the market for 20 years + and have learned a lot (though I am no pro).

I run an environmental remediation company and have been in business for 30+ years (living mostly in the commercial industry, with some residential).

I see an uptick in the economy as my field typically is at the forefront of many construction projects (we remove all the nasties out of the building making it safe for other contractors & company personnel). We handle everything from dirty-dirt, HAZMAT to asbestos, lead & mold.

Managed to stay busy last year with all the covid stuff but many larger projects were on hold and profit was harder to come by. Got a little slow over the winter but the flood gates have opened back up and I am am very, very busy...many architects are cranking out plans very good sign for the economy.

Hope all is well and appreciate your insight MC.

[mcsharkey]

How're You doing Enviro. Spoke with our new Investor Relation Rep. This has been a wholesale swap at the top this year. COO, President, CEO now our head scientist (Guissepe ? (so) Fiore).

And no real updates. IR says that's on it's way. A few Institutional Investment firms were in that buy in. They want answers too.

Our extensive annual report is being prepared AND THAT WILL HOLD ALL OUR ACCOMPLISHMENTS AND MOVES.

They're shooting for May, mid-May on the outside. Proxy and annual meeting in August. I blew that. They'll also be revising corporate presentation; holds all the milestone on sheet 5.

We'll see.

I blew the proxy and Annual meeting saying May. That is earnings report though. With all the elaborations they promise. Dunno. .at just be a song and dance. ALOT OF CHANGES. I came away satisfied, but that's his job.

Oh yeah, the last PR about new science officer suppose to be revealing. Over and over is expanding to other cancers. I forgot to ask about TYME 19 (COVID).

H

ALL I got. and GLTUA