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Integrated Cannabis Company Inc. (ICNAF)

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Last Post: 11/11/2018 12:16:49 PM - Followers: 44 - Board type: Free - Posts Today: 0

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Over the last three decades, intraoral dosage forms have been evolving as an acceptable and in some cases as the preferred, alternative to conventional tablets and capsules. Among them, Oral sprays are the fastest, most effective and comfortable way to take medicines, nutrients, minerals and vitamins. They have been acquiring important position in the market by overcoming previously encountered administration problems and contributing to extension of patent life.

Oral sprays have the unique property of rapidly releasing the drug in the oral cavity, thus obviating the requirement of water during administration. Therefore, these dosage forms have lured the market for a certain section of the patient population which includes dysphagic, bed ridden, and psychic, geriatric patients. This article focuses on the transmucosal view , spray formulation aspects , advances made so far in the field oral sprays and patented technologies.






 








 

Abstract: Nitroglycerin (glyceryl trinitrate, CAS 55-63-0, NTG) administered with an oral spray may be more effective in relieving anginal pain than sublingual tablets especially when the patient’s mouth is dry. In this study, the effect of a NTG oral spray (Myocor Spray) on exercise-induced angina was compared with that of a sublingual tablet in relation to the oral dryness. In 17 patients with effort angina, graded bicycle exercise was performed twice at an interval of one week.

Exercise was discontinued upon the onset of moderate anginal pain. Immediately after exercise, the oral dryness was evaluated by touching the tip of the tongue with a blotting paper for a moment. Then, 0.3 mg of NTG was administered by either a squirt of spray or a sublingual tablet in a randomized crossover fashion. Exercise results were reproducible between two exercise tests. According to the extent of the wet area of the blotting paper, the subjects were divided into two groups.

In 7 patients of the wet group, the remission times of chest pain and ST segment depression were not significantly different by the formulation of NTG. In 10 patients of the dry group, however, both chest pain and ST depression more rapidly recovered with use of the oral spray (p < 0.05 and p < 0.05, respectively). These results strongly suggest that the NTG oral spray is superior to the sublingual tablet in relieving anginal attacks, when the oral wetness is decreased.







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https://www.facebook.com/xsprays/
 
 
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#293   Lol, TRTC should have thought about opening dispensaries Etailer 11/11/18 12:16:49 PM
#292   They have been adding dispensaries left and right. badbass58 11/11/18 12:12:36 PM
#291   Lol, is this some kind of joke? Etailer 11/09/18 09:12:03 AM
#290   Integrated Cannabis Company, Inc. Signs Definitive Agreement with PotterBanker 11/07/18 08:52:46 AM
#289   TCNNF. Now there a real legimiate company. badbass58 11/06/18 09:41:35 AM
#288   Look at what their doing. Pump and dump, investorpro1 11/06/18 06:42:37 AM
#287   ZZZZZzzzzzzZZZZzzzz. The pump and dump promoters for badbass58 11/06/18 05:10:22 AM
#286   100 % agree simmons420 11/03/18 11:29:40 AM
#285   Lol, ya, right. See you should get out. Lol investorpro1 11/01/18 08:28:58 PM
#284   ICNAF ~~~~>keep watching lol PotterBanker 11/01/18 10:55:39 AM
#283   haha, go ICNAF....Boom! greenwillow 10/31/18 11:39:45 AM
#282   keep watching. lol PotterBanker 10/31/18 11:37:44 AM
#281   No, just someone saying an RS. No way.. investorpro1 10/30/18 08:50:05 PM
#280   RS? Was there mention of an RS? PotterBanker 10/30/18 02:50:50 PM
#279   No way in hell a reverse split. If investorpro1 10/30/18 02:47:23 PM
#278   No way in hell a reverse split. If investorpro1 10/30/18 02:47:22 PM
#277   keep watching. lol PotterBanker 10/30/18 12:06:15 PM
#276   scam...lol greenwillow 10/30/18 12:04:09 PM
#275   those .55's already looking good PotterBanker 10/30/18 11:59:46 AM
#274   OS 36,300,559 MCAP 20,691,318 Revs coming soon: PotterBanker 10/30/18 11:58:22 AM
#273   Impacto better load up more before it hits badbass58 10/30/18 11:40:51 AM
#272   Impacto better load up more before it hits badbass58 10/30/18 11:40:49 AM
#271   right back to where it was before mostly...scam greenwillow 10/30/18 11:28:24 AM
#270   why low .40's? PotterBanker 10/30/18 11:24:39 AM
#269   If I had some free funds, I would toolandAPC 10/30/18 11:21:16 AM
#268   low 40s coming, imo greenwillow 10/30/18 11:19:27 AM
#267   How about .55 ICNAF??? Looks like a bargain. PotterBanker 10/30/18 11:18:25 AM
#266   Impacto.....still adding. You have been adding since badbass58 10/29/18 03:54:29 PM
#265   Yup, no worry. We haven't even begun. investorpro1 10/29/18 03:46:25 PM
#264   Double bottom NYfinest 10/29/18 12:46:47 PM
#263   I agree , nothing goes up forever, simmons420 10/29/18 12:25:51 PM
#262   A joke. I lost too much to quite. NYfinest 10/29/18 12:16:28 PM
#261   Once the market turns this one will fly. investorpro1 10/29/18 12:03:45 PM
#260   Thoes are the area of resistance I'm looking at. simmons420 10/29/18 10:32:51 AM
#259   probably will not be buying into this one Etailer 10/29/18 10:28:53 AM
#258   probably will not be buying into this one Etailer 10/29/18 10:28:52 AM
#257   Looking for a break of .80 then that 1.00 simmons420 10/29/18 10:04:14 AM
#256   It is getting the pump going Etailer 10/28/18 11:05:24 PM
#255   Yup the market isn't going to get killed investorpro1 10/26/18 12:30:56 PM
#254   Not looking for a lot of movement her ForexGuy99 10/26/18 12:18:33 PM
#253   Everything is getting beaten down ,EXCEPT this stock. investorpro1 10/26/18 11:07:17 AM
#252   Integrated Cannabis Company, Inc. Enters into Licensing Agreement JohnCM 10/25/18 05:49:26 PM
#250   lol yeah I have lots lots and adding ;) Impacto 10/25/18 02:58:31 PM
#249   WOW.This company is screaming up on the news!!!!!! badbass58 10/25/18 02:51:38 PM
#248   I've seen a ton of great articles on investorpro1 10/25/18 02:05:30 PM
#247   Integrated Cannabis Company, Inc. Enters Into Licensing Agreement lithiumjr 10/25/18 08:27:55 AM
#246   Good news coming today we entered agreement for STOCK PROF 10/25/18 08:11:53 AM
#245   Impacto...I went to buy shares but it said badbass58 10/24/18 09:35:38 AM
#244   Buying more tomorrow:) Impacto 10/23/18 10:16:01 PM
#243   Yup. It will come back strong investorpro1 10/23/18 11:27:46 AM
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