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Inspyr Therapeutics Inc. (NSPX)

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Last Post: 8/16/2018 8:14:03 PM - Followers: 49 - Board type: Free - Posts Today: 0

2511 N Loop 1604 W
Suite 204
San Antonio, TX 78258
Phone: 210-479-8112


Craig Dionne President, CEO, CFO
Russell Richerson COO, Secretary

Shares Outstanding 27,392,100 a/o Mar 09, 2014
Float Not Available
Authorized Shares 80,000,000 a/o Jun 30, 2009

Latest Report Mar 31, 2014 10-Q
CIK 0001421204
Fiscal Year End 12/31

About GenSpera

GenSpera’s technology platform combines a powerful, plant-derived cytotoxin (thapsigargin) with a prodrug delivery system that provides for the targeted release of drug candidates within a tumor. Unlike typical chemotherapeutic agents, thapsigargin results in cell death irrespective of the rate of cell division, which may provide an effective approach to kill both fast- and slow-growing cancers. GenSpera’s lead drug candidate, G-202, is activated by the enzyme PSMA, which is found at high levels in the vasculature of liver and glioblastoma cancers and in the vasculature of almost all other solid tumors. G-202 is therefore expected to have potential efficacy in a wide variety of tumor types.

G-202 Phase II clinical trials are underway in both hepatocellular carcinoma and glioblastoma patients.

Business Description

We are a biotechnology company focused on the discovery and development of pro-drug cancer therapeutics, an emerging medical science. A pro-drug is an inactive precursor of a drug that is converted into its active form only at the site of the tumor. We were incorporated as a Delaware corporation in 2003.

GenSpera Inc. (GenSpera) is a development-stage pharmaceutical company. The Company is focused on the development of prodrug cancer therapeutics for the treatment of solid tumors including prostate, liver, brain and other cancers. A prodrug is an inactive precursor of a drug that is converted into its active form only at the site of the tumor. The Company has four prodrug candidates: G-202, G-114, G-115 and G-301. The Company's primary focus is the clinical development of its compound, G-202, a therapeutic agent with a mechanism of action. G-202 is in Phase II Clinical Trial. G-114 is validated efficacy in pre-clinical animal models. Pilot toxicology is completed for G-115. G-301 is validated efficacy in pre-clinical animal models. The Company is also conducting a Phase II clinical trial to test the utility of G-202 in patients with hepatocellular carcinoma (liver cancer). As of March 27, 2013, it treated one patient in this Phase II trial.

GenSpera harnesses a novel biomedical technology platform to deliver a powerful toxin directly to tumors

  • Phase II clinical trials for lead compound, G-202, are underway in two indications:
    • Hepatocellular carcinoma, or liver cancer
    • Glioblastoma, or brain cancer
  • Experienced and motivated team drives the process:
    • Core team has extensive experience in successfully identifying and bringing oncology treatments to the clinic.
    • Scientific Advisory Board is comprised of leading researchers who are both the inventors of the technology and shareholders.
  • Technology platform supports the development of a suite of drugs targeted at different cancers, as well as other applications such as imaging.
  • Over 15 years of research at Johns Hopkins Medical Center and other renowned research centers, including the University of Copenhagen.
    • Strong intellectual property portfolio
    • No milestones or royalty payments owed to third parties.
  • Leverage the team's passion and expertise in identifying promising treatments and bringing them to the clinic.

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#1065   Per the last financing agreement, there was a floridaboy 08/16/18 08:14:03 PM
#1064   It’s so odd that they have completely gone Mrragu 08/16/18 08:08:08 PM
#1063   Accumulation has been pretty heavy overall from .01-.02. floridaboy 08/16/18 05:04:49 PM
#1062   Man floridaboy this is a tough stock to Law of Averages 08/16/18 04:49:23 PM
#1061   It'll come... Might not be in the next floridaboy 08/16/18 06:47:27 AM
#1060   Lowe has been ceo for 2 yrs. (8/02/16) Mrragu 08/14/18 12:55:08 PM
#1059   Tug-o-war until updates...Somebody dropped $10,000 on shares Monday, floridaboy 08/08/18 06:20:34 AM
#1058   If the bid would come up closer to Law of Averages 08/07/18 10:53:38 AM
#1057   Someone took a pretty big bite... floridaboy 08/07/18 05:51:34 AM
#1056   Convertible debentures converting to common stock thinking that Mrragu 08/06/18 04:21:50 PM
#1055   Good question... floridaboy 08/06/18 02:46:00 PM
#1054   Who's buying all these shares. Law of Averages 08/06/18 02:37:51 PM
#1053   Million up, 110,000 down, hmmm... floridaboy 08/06/18 02:11:47 PM
#1052   Little love @ NSPX today, nice... floridaboy 08/06/18 01:18:17 PM
#1051   Record day volume here 999,326 are we going Law of Averages 08/06/18 12:44:10 PM
#1050   Thanks, checked it out...I cannot see this dude floridaboy 07/26/18 07:53:51 PM
#1049   Go to FLG Partners/ team/Chris Lowe ( Nspx Mrragu 07/26/18 12:04:37 PM
#1048   Good looking out floridayboy. Law of Averages 07/20/18 02:46:11 PM
#1047   009, 01, 013, 0135, 015... floridaboy 07/20/18 02:02:48 PM
#1046   Hey Floridaboy what's after .009 on L2 if Law of Averages 07/20/18 01:56:07 PM
#1045   Hey man..I do and it is... floridaboy 07/20/18 04:34:26 AM
#1044   Hey Floridaboy do you have L2 for NSPX? Law of Averages 07/19/18 11:31:01 PM
#1043   That's a good thing man...No disrespect intended floridaboy 07/19/18 09:32:45 PM
#1042   Hey floridaboy how about it took 2 weeks Law of Averages 07/19/18 09:20:00 PM
#1041   I agree man, will be looking to add floridaboy 07/19/18 05:37:34 PM
#1040   I’m hanging been hanging since GNSZ days and Mrragu 07/19/18 05:34:36 PM
#1039   Trying to create some fear, just hang tight floridaboy 07/19/18 02:58:03 PM
#1038   500K doesn’t last long in the clinical stage Mrragu 07/16/18 09:48:10 AM
#1037   I hear ya...Gonna hear something, at some point. floridaboy 07/14/18 07:44:22 AM
#1036   I'm holding tight. I'm more of a chart Law of Averages 07/13/18 08:16:02 PM
#1035   Never any news concerning progress on the drug Mrragu 07/13/18 10:06:14 AM
#1034   Roger that... floridaboy 07/06/18 05:26:48 AM
#1033   Probably Sabby Fund.. been floating them money since Mrragu 07/05/18 09:41:39 AM
#1032   Trying to stay alive until something positive happens Mrragu 07/05/18 06:45:18 AM
#1031   Appears to be the same institutional investor from floridaboy 07/05/18 04:50:36 AM
#1030   Yeah I didn't quite understand the recent 8k. Law of Averages 07/04/18 11:39:25 PM
#1029   Anybody read the 8k? Thoughts? Institutional investor? floridaboy 07/03/18 07:15:54 PM
#1028   Just a whisper from management...New company emerging? floridaboy 06/28/18 06:47:12 PM
#1027   Fire! in the hole. It's about to explode. Law of Averages 06/28/18 01:31:50 PM
#1026   bids are stacking...getting close spion 06/28/18 01:04:33 PM
#1025   Agreed this is about to make a run soon. Law of Averages 06/28/18 12:05:06 PM
#1024   someone is loading up for a big move soon spion 06/28/18 11:55:55 AM
#1023   Someone got lucky getting those cheapies at .008 Law of Averages 06/28/18 10:49:53 AM
#1022   Same here but fidelity won’t let buy (rule Mrragu 06/27/18 07:15:22 AM
#1021   I will be adding to my position soon, floridaboy 06/26/18 08:24:47 PM
#1020   Favor packaging IP from Genspera an L&C and Mrragu 06/23/18 10:52:44 AM
#1019   Still think new company will emerge from merger, floridaboy 06/23/18 08:28:20 AM
#1018   Somebody still trying to hold it back... floridaboy 06/22/18 03:17:51 PM
#1017   If this closes at .02 or higher this Law of Averages 06/22/18 02:45:30 PM
#1016   I used my cigar lighter.....she's gonna blow wamuvoodoo 06/22/18 01:36:15 PM