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Inspyr Therapeutics Inc. (NSPX)

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Last Post: 6/14/2018 4:21:23 PM - Followers: 48 - Board type: Free - Posts Today: 0

2511 N Loop 1604 W
Suite 204
San Antonio, TX 78258
Phone: 210-479-8112


Craig Dionne President, CEO, CFO
Russell Richerson COO, Secretary

Shares Outstanding 27,392,100 a/o Mar 09, 2014
Float Not Available
Authorized Shares 80,000,000 a/o Jun 30, 2009

Latest Report Mar 31, 2014 10-Q
CIK 0001421204
Fiscal Year End 12/31

About GenSpera

GenSpera’s technology platform combines a powerful, plant-derived cytotoxin (thapsigargin) with a prodrug delivery system that provides for the targeted release of drug candidates within a tumor. Unlike typical chemotherapeutic agents, thapsigargin results in cell death irrespective of the rate of cell division, which may provide an effective approach to kill both fast- and slow-growing cancers. GenSpera’s lead drug candidate, G-202, is activated by the enzyme PSMA, which is found at high levels in the vasculature of liver and glioblastoma cancers and in the vasculature of almost all other solid tumors. G-202 is therefore expected to have potential efficacy in a wide variety of tumor types.

G-202 Phase II clinical trials are underway in both hepatocellular carcinoma and glioblastoma patients.

Business Description

We are a biotechnology company focused on the discovery and development of pro-drug cancer therapeutics, an emerging medical science. A pro-drug is an inactive precursor of a drug that is converted into its active form only at the site of the tumor. We were incorporated as a Delaware corporation in 2003.

GenSpera Inc. (GenSpera) is a development-stage pharmaceutical company. The Company is focused on the development of prodrug cancer therapeutics for the treatment of solid tumors including prostate, liver, brain and other cancers. A prodrug is an inactive precursor of a drug that is converted into its active form only at the site of the tumor. The Company has four prodrug candidates: G-202, G-114, G-115 and G-301. The Company's primary focus is the clinical development of its compound, G-202, a therapeutic agent with a mechanism of action. G-202 is in Phase II Clinical Trial. G-114 is validated efficacy in pre-clinical animal models. Pilot toxicology is completed for G-115. G-301 is validated efficacy in pre-clinical animal models. The Company is also conducting a Phase II clinical trial to test the utility of G-202 in patients with hepatocellular carcinoma (liver cancer). As of March 27, 2013, it treated one patient in this Phase II trial.

GenSpera harnesses a novel biomedical technology platform to deliver a powerful toxin directly to tumors

  • Phase II clinical trials for lead compound, G-202, are underway in two indications:
    • Hepatocellular carcinoma, or liver cancer
    • Glioblastoma, or brain cancer
  • Experienced and motivated team drives the process:
    • Core team has extensive experience in successfully identifying and bringing oncology treatments to the clinic.
    • Scientific Advisory Board is comprised of leading researchers who are both the inventors of the technology and shareholders.
  • Technology platform supports the development of a suite of drugs targeted at different cancers, as well as other applications such as imaging.
  • Over 15 years of research at Johns Hopkins Medical Center and other renowned research centers, including the University of Copenhagen.
    • Strong intellectual property portfolio
    • No milestones or royalty payments owed to third parties.
  • Leverage the team's passion and expertise in identifying promising treatments and bringing them to the clinic.

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#1010   OMG an uptic... albeit a small one but Mrragu 06/14/18 04:21:23 PM
#1009   No real selling under .01, traders just squeezing floridaboy 06/14/18 05:41:45 AM
#1008   I'm still here too guys. I hate the Law of Averages 06/13/18 07:57:04 PM
#1007   patience is something I have ,been waiting 10 wamuvoodoo 06/13/18 09:12:36 AM
#1006   Stay patient, better silence than something fluffy... floridaboy 06/13/18 05:58:03 AM
#1005   Call FLG Partners ( Lowe is a manager). Mrragu 06/12/18 10:59:11 AM
#1004   why doesnt the ownership gives us any updates wamuvoodoo 06/11/18 09:34:58 PM
#1003   Do zombies ever come back from the dead? Mrragu 06/06/18 11:26:22 AM
#1002   Positive update and .03-.05 will come in a flash... floridaboy 06/05/18 05:09:54 PM
#1001   Infinity bottom... Sugarplum 06/05/18 04:57:30 PM
#1000   Grabbed another handful @ .01, NSPX management will floridaboy 05/31/18 05:59:42 PM
#999   Need a word, filing from company... floridaboy 05/25/18 08:22:07 PM
#998   Agreed floridaboy. The bottom is definitely in this Law of Averages 05/25/18 07:32:10 PM
#997   That was me, no luck...NSPX way oversold, just floridaboy 05/25/18 05:04:46 PM
#996   Big 400k bid at .0085 this stock is Law of Averages 05/25/18 03:07:31 PM
#995   Falling into the dead zone. No volume, no Mrragu 05/25/18 11:25:43 AM
#994   Power of the brush... floridaboy 05/23/18 06:53:04 PM
#993   People might be waiting for subpennies. But I Law of Averages 05/22/18 03:02:26 PM
#992   Accumulation seems to be dieing out but the Mrragu 05/22/18 01:29:34 PM
#991   Agreed floridaboy. I just wish they were still Law of Averages 05/20/18 12:44:37 PM
#990   I am curious as well man. They have floridaboy 05/20/18 08:02:26 AM
#989   I can hardly wait floridaboy. This might be Law of Averages 05/19/18 08:49:04 PM
#988   When they file something we will know they floridaboy 05/19/18 08:52:46 AM
#987   I get that part. But the part that's Law of Averages 05/18/18 09:03:50 PM
#986   Showing no because of failed reporting or no Mrragu 05/18/18 04:33:58 PM
#985   No info at this point would make sense... floridaboy 05/18/18 04:19:59 PM
#984   Hey guys why is NSPX showing Pink No Law of Averages 05/18/18 03:55:47 PM
#983   I just finally got filled at .01 took Law of Averages 05/18/18 03:08:00 PM
#982   That it does... floridaboy 05/18/18 12:57:30 PM
#981   A MEGA load of patience has been extended Mrragu 05/18/18 10:14:38 AM
#980   MM's collecting shares the last couple months, not floridaboy 05/18/18 07:44:12 AM
#979   Silence is not golden... as PPS drops below Mrragu 05/15/18 01:56:07 PM
#978   Accumulation has been heavy from .02 down to floridaboy 05/11/18 05:47:27 PM
#977   Bids need to move up.. but with the Mrragu 05/11/18 04:28:22 PM
#976   volume 500k..we'll c what tomorrow brings wamuvoodoo 05/07/18 09:46:54 PM
#975   Accumulation, accumulation, accumulation continues @ NSPX... floridaboy 05/07/18 04:19:00 PM
#974   True, little positive news would be just what floridaboy 05/05/18 07:10:54 AM
#973   Volume has exited the stage.. all waiting on Mrragu 05/04/18 05:13:43 PM
#972   No takers anywhere...Still being squeezed, accumulated floridaboy 05/03/18 06:03:07 PM
#971   WOW! Low volume takers at the bid! Mrragu 05/03/18 04:52:21 PM
#970   Accumulation until positive updates, no rush... floridaboy 05/02/18 02:37:25 PM
#969   I'm good with 350,000...let's make some cheese wamuvoodoo 05/01/18 11:21:04 PM
#968   One positive update...They keep squeezing her I may floridaboy 05/01/18 10:30:04 PM
#967   setting up for an explosion wamuvoodoo 05/01/18 10:28:07 PM
#966   Squeezing her still... floridaboy 05/01/18 04:32:07 PM
#965   AGREED!! NSPX has ALL the key ingredients G-Schmoney 04/30/18 02:30:35 PM
#964   Come too far, recently completed merger and got floridaboy 04/29/18 07:20:11 PM
#963   Chris Lowe (ceo) and partner with FLG Group. Mrragu 04/29/18 05:12:20 PM
#962   I hear ya, I am just throwing out floridaboy 04/29/18 12:57:01 PM
#961   Company ran out of funds. What shall we Dina 04/29/18 12:26:06 PM