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Get out of here with your nonsense! If you think Biden got 80 million votes.... you are just plain stupid!
Oh I see TDS got you. Nancy and Mitch created this theater.
The Uniparty Swamp is one party always has been. It's how they and their relatives
all become Uber wealthy and powerful while the media runs this foe struggle between parities.
Term Limits platform wins the next election. Enough with the systemic corruption.
FOX news is no different they just play their roll in this Kabuki Theater lol
Gin everyone up to hate each other and keep control.
I wish you only peace and love, sincerely
But it's OK when a pathetic loser uses his FOX megaphone to falsely claim the election was stolen and fires up his right wing Proud Boys, QAnon and KKK supporters to storm the Congress, wound 100 police officers and cause the death of 5 or 6 people. They would have hung Pence if they caught him. Too bad John McCain is not around to straighten out his former colleagues.
CNN's been saying that for 4 years yet we don't see hords
of racists they claim are everywhere.
Meanwhile cities burned and Americans were assaulted, some killed
by leftist orgs. and the media is silent.
Media has too much control over to many minds. It's really sad.
He doesn't hate himself. He hates bigotry which goes back to slavery and segregation...and which white supremacists spout today.
I don't think he does NK any service with his
personal public rantings.
I could care less if he hates himself. Hate away.
If attacking people like Brennan who have honorably served their country works for you good luck with that.
White guilt is so pathetic it does nothing to elevate others.
My friends and family are Every color. "White people" are not their concern
jobs and feeding their families are their priorities.
But hey if self hate works for you good luck with that.
My ancestry is Irish, Scots and Viking...but I too am ashamed of White bigotry in America...good grief indeed!
John Brennan's concern is that he's too white- good grief
2 good and able men who have faithfully served their country now on board!
About John Brennan
Mr. Brennan served for 25 years in a variety of roles at the CIA, rising from analyst to station chief, and finally being appointed as the agency’s Director by President Barack Obama. He also served as Deputy National Security Advisor for Homeland Security and Counterterrorism. Brennan earned a Bachelor of Arts degree from Fordham University, and is a Distinguished Fellow at the Fordham University Law School. He earned a Master of Arts from the University of Texas at Austin, where he currently serves as a Distinguished Non-Resident Scholar and a senior advisor to the University’s Intelligence Studies Projects.
About Wesley Clark
General Clark served for 34 years in the U.S. Army, rising through the ranks to earn his fourth star as a full general in 1996. He served as the Supreme Allied Commander Europe of NATO where he commanded Operation Allied Force in the Kosovo War. Highly decorated throughout his career, Gen. Clark was awarded the U.S. Presidential Medal of Freedom by President Bill Clinton. He is a graduate of the U.S. Military Academy at West Point, where he was class valedictorian. After graduating from West Point, General Clark was awarded a Rhodes Scholarship to the University of Oxford where he earned degrees in Philosophy, Politics and Economics. He earned a master’s degree in military science from the Command and General Staff College. General runs Wesley K. Clark and Associates consulting firm and is Chairman and CEO of Enverra, a boutique investment bank.
Possibly on board because of the potential oral
Covid cure / treatment.
Current Vaccines treat the variant
NK's solution kills the virus using your immune system. No stigma tied to
it like mNRA drugs.
What other diseases can this platform work against?
Think about the potential Geo Political influence.
All that being said I own it for Cancer vaccines. Want to see
pancreatic cancer destroyed.
Me either.... but I suspect they are there to grant political influence.
Don't like either of the Deep Staters added to the board
today but I guess it's how the game is played.
NantKwest Inc (NK)
39.2 ? 2.25 (6.09%)
Volume: 1,454,570 @02/19/21 7:59:36 PM EST
Bid Ask Day's Range
35.49 42.57 36.54 - 39.71
NK Detailed Quote
READING NantKwest Inc (NK)
34.85 ? 3.93 (12.71%)
Volume: 2,239,543 @02/16/21 7:59:44 PM EST
Bid Ask Day's Range
33.69 34.84 29.87 - 34.7
NK Detailed Quote
NantKwest Inc (NK)
34.85 ? 3.93 (12.71%)
Volume: 2,239,543 @02/16/21 7:59:44 PM EST
Bid Ask Day's Range
33.69 34.84 29.87 - 34.7
NK Detailed Quote
71% complete Remission for bladder cancer
FDA approval eminent IMO
many more in the Pipeline
If Covid cure works this summer
SP will be ????? I have no idea!
Take a look at Jan 2022 35 calls
still cheap IMO .....going to 150
I own them and others
JMO as you know
wow pps NantKwest Inc (NK)
33.55 ? 2.63 (8.51%)
Volume: 1,547,424 @02/16/21 1:43:57 PM EST
Bid Ask Day's Range
33.48 33.64 29.87 - 33.79
NK Detailed Quote
NantKwest Inc (NK)
33.56 ? 2.64 (8.54%)
Volume: 1,535,797 @02/16/21 1:41:37 PM EST
Bid Ask Day's Range
33.32 33.56 29.87 - 33.79
NK Detailed Quote
will do
mick take a look at
OMQS secured Homeland Security contract today
only 2 million float 4 million OS
that one going higher
in MARA board. Great NK news today. Thanks
in 'NantKwest (NK)'
Thanks mick now do
MARA it's my #2 holding behind NK. Put it on your radar
Great NK News!
These T cells will kill the virus not mask it's receptors.
Oral Vaccine stable at room temperature being tested
3.71 (14.1%) Upgrade to Real-Time
Afterhours (Closed)
ImmunityBio & NantKwest Announce FDA Authorization to Study hAd5 T-Cell COVID-19 Vaccine for Combination of Subcutaneous, Ora...
February 11 2021 - 06:13PM
Business Wire
FDA authorized the expansion of the active Phase 1 COVID-19 vaccine trial and a second trial to test a novel combination of T-cell-based hAd5 subcutaneous prime vaccine with a room-temperature oral or sublingual boost, to induce comprehensive immune protection through CD4+ and CD8+ T cells to both Spike (S) and Nucleocapsid (N) antigens, as well as generate systemic and mucosal antibodies
The first COVID-19 trials conducted to deliver both S and N proteins via multiple routes (skin, gut, or under the tongue) to activate the entire immune system and drive T-cell and B-cell memory, which are required for long-term immune protection
Oral, room-temperature boost that stimulates immunity to both S and N proteins could potentially serve as a universal boost to other S-based vaccines while also targeting escape mutants
Testing of novel combination of oral boost to subcutaneous prime is based on positive NIH/BARDA-sponsored non-human primate data showing potent T-cell and antibody response to hAd5 after oral boost, with rapid inhibition of virus replication to undetectable levels following SARS-CoV-2 challenge
ImmunityBio, Inc., a privately-held immunotherapy company, and NantKwest, Inc. (NASDAQ: NK), a clinical-stage, natural killer cell-based therapeutics company, today announced they have received FDA authorization to expand Phase I testing of a bivalent hAd5 T-cell COVID-19 vaccine. The FDA authorized the expansion of a currently active multi-cohort trial of the subcutaneous version of the vaccine in order to study the addition of sublingual boosts. The FDA also authorized a second Phase I study that will examine the addition of an oral boost to the subcutaneous prime administration. As a result, the companies will enroll another 105 participants in the U.S. trials of their vaccine candidate, which is unique in targeting both the spike (S) and nucleocapsid (N) proteins of the SARS-CoV-2 virus.
The expectations of inducing protective immune responses in healthy volunteers – with this novel combination of an oral boost with a subcutaneous prime – are based on the positive findings reported in the NIH/BARDA-sponsored Non-Human Primate (NHP) study. This recent data showed that when administered with an oral boost, the bivalent vaccine resulted in potent stimulation of S- and N-specific T cells with potent antibody release from memory B cells following viral challenge. Additionally, activation of the full immune system by S and N proteins resulted in complete viral clearance of SARS-CoV-2 in lung and nasal passages following the challenge. On the basis of these findings, ImmunityBio has expanded the current Phase 1 study of subcutaneous prime with oral or sublingual boost to explore the potential of this second-generation vaccine to reduce disease and transmission of the virus.
The oral trial is a new study (NCT04732468) and the sublingual trial is the cohort C expansion to the Phase 1 subcutaneous trial (NCT04591717), which was initiated last Fall. Both oral and sublingual trials are anticipated to begin this month and will be conducted at two sites in California. Based on the findings of these trials involving over 100 participants, the optimal combination of route of administration and dose will be determined and entered into the Phase 2 / 3 design.
“The NHP study findings reinforce our hypothesis that a T-cell-based vaccine could be protective, not only in preventing mild, moderate, and severe disease, but also in potentially limiting transmission of the virus,” said Patrick Soon-Shiong, MD, Chairman and CEO of ImmunityBio. “We believe that the key to creating long-term immunity to the SARS-CoV-2 virus and overcoming the variants that are rapidly developing around the world is to create a vaccine that activates not only antibodies but also memory B and T cells to multiple antigens. Furthermore, room-temperature stable formulations for oral delivery have the potential to solve the cold-chain challenges of distribution and the ability to generate mucosal IgA antibody barriers to the virus in the upper respiratory tract where it first enters the body.”
One Vaccine, Two Trials, Three Routes of Immune Protection
The first two cohorts of the Phase Ib, open label, dose-ranging study (NCT04591717) of the vaccine received two different dose levels (.5 and 1ml). Participants received two subcutaneous injections 21 days apart. No grade three or four AEs and no SAEs were observed at either dose level and, in the intermediate (1ml) dose group, immunogenicity was observed as early as 14 days after the prime. An additional group of 40 subjects will be enrolled to evaluate safety, reactogenicity, and immunogenicity of the combination of hAd5 in four different cohorts receiving sublingual and subcutaneous formulations to select an optimal combination dose for future studies.
The second Phase 1b trial (NCT04732468) is designed to assess the safety, reactogenicity, and immunogenicity of the combination of hAd5 in oral capsule and subcutaneous formulations; and to select an optimal combination dose for future studies. Up to 65 subjects will be enrolled in the four-cohort study, which is anticipated to begin in Q1.
About the T-Cell-Based Vaccine Candidate
Developed by ImmunityBio and manufactured by NantKwest, this second generation hAd5 vectored vaccine is unique in targeting both spike (S) and nucleocapsid (N) SARS-CoV-2 proteins to generate B and T cell memory to these antigens and long-term immunity to the virus. Most of the COVID-19 vaccines approved by the FDA or in late-stage clinical trials deliver only the spike protein, which has already mutated several times. Another unique characteristic of the hAd5 design is its use of a second-generation hAd5 platform that was developed to elicit anti-SARS-CoV-2 immune responses even in Ad-immune individuals, meaning subjects can receive the vaccine multiple times, if necessary. The stimulation of anti-hAd5 immune responses is attenuated with the second-generation platform in comparison with the first-generation platforms, due to additional genetic deletions. The hAd5 room temperature-stable oral capsules were developed in partnership with UK-based biotechnology company iosBio.
Phase I trials have been initiated in the U.S. and recruitment is set to begin in February in Cape Town, South Africa for a trial (NCT04710303) of subcutaneous administration to be followed by additional trials using sublingual delivery and room temperature-stable oral capsules.
NantKwest Transaction
As previously announced, on December 21, 2020, ImmunityBio entered into an agreement to combine in a stock-for-stock transaction with NantKwest (NASDAQ: NK). The combination, which is expected to close in the first half of 2021, will create a leading immunotherapy and cell therapy company focused on oncology and infectious disease.
About ImmunityBio
ImmunityBio, Inc. is a late-clinical-stage immunotherapy company developing next-generation therapies that drive immunogenic mechanisms for defeating cancers and infectious diseases. The company’s immunotherapy platform activates both the innate (natural killer cell and macrophage) and adaptive (T-cell) immune systems to create long-term “immunological memory.” This novel approach is designed to eliminate the need for high-dose chemotherapy, improve upon the outcomes of current CAR T-cell therapies, and extend beyond checkpoint inhibitors.
ImmunityBio’s platform is based on the foundation of three separate modalities: antibody cytokine fusion proteins, synthetic immunomodulators, and second-generation human adenovirus (hAd5) vaccine technologies.
Anktiva™ (ImmunityBio’s lead cytokine infusion protein) is a novel interleukin-15 (IL-15) superagonist complex and has received Breakthrough Therapy and Fast Track Designations from the U.S. Food and Drug Administration (FDA) for BCG-unresponsive CIS non-muscle invasive bladder cancer (NMIBC). The company is also in Phase 2 or 3 trials for indications such as first- and second-line lung cancer, triple-negative breast cancer, metastatic pancreatic cancer, recurrent glioblastoma, and soft tissue sarcoma in combination with the company’s synthetic immune modulator (Aldoxorubicin).
ImmunityBio is also developing therapies, including vaccines, for the prevention and treatment of HIV, influenza, and the coronavirus SARS-CoV-2 with its second-generation human adenovirus (hAd5) vaccine technologies.
About NantKwest
NantKwest (NASDAQ: NK) is an innovative, clinical-stage, immunotherapy company focused on harnessing the power of the innate immune system to treat cancer and infectious diseases. NantKwest is the leading producer of clinical dose forms of off-the-shelf natural killer (NK) cell therapies. The activated NK cell platform is designed to destroy cancer and virally-infected cells. The safety of these optimized, activated NK cells—as well as their activity against a broad range of cancers—has been tested in phase I clinical trials in Canada and Europe, as well as in multiple phase I and II clinical trials in the United States. By leveraging an integrated and extensive genomics and transcriptomics discovery and development engine, together with a pipeline of multiple, clinical-stage, immuno-oncology programs, NantKwest’s goal is to transform medicine by bringing novel NK cell-based therapies to routine clinical care. NantKwest is a member of the NantWorks ecosystem of companies. For more information, please visit www.nantkwest.com.
Forward-Looking Statements
The "Pill" NOW being tested in S. Africa:
https://www.researchprofessionalnews.com/rr-news-uk-innovation-2021-2-covid-vaccine-pill-enters-clinical-trials/
IT COULD IN THESE MARKETS $NK
I like NK to 100 see FATE
Market looking a bit shaky. We shall see
MUX has high action coming
Definitely put on radar. Big volume last week.
If Copper project
in Argentina gets funded or Spun out
SP could do something stupid. Gold and silver need to break old highs.
NantKwest Executive Chairman Dr. Patrick Soon-Shiong to Present at 39th Annual J.P. Morgan Healthcare Conference on January 13, 2021 -
https://finance.yahoo.com/news/nantkwest-executive-chairman-dr-patrick-140000875.html
NK
[-chart]www.stockscores.com/chart.asp?TickerSymbol=NK&TimeRange=180&Interval=w&Volume=1&ChartType=CandleStick&Stockscores=1&ChartWidth=1100&ChartHeight=480&LogScale=&Band=&avgType1=&movAvg1=&avgType2=&movAvg2=&Indicator1=None&Indicator2=None&Indicator3=None&Indicator4=None&endDate=&CompareWith=&entryPrice=&stopLossPrice=&candles=redgreen[/chart]
WKLY
Motley Fool just came out saying they like NK better than FATE. However, NK still not in their top-ten.
Experience... on the 22nd NK reached a 5 year high. If you're under the impression that charts go straight up you're sadly mistaken.
And that pull back to the high $13 was how I felt at the time of writing.
A year ago in November NK was trading near a buck and just finished a 20 fold run to near $20? At this point now that the momentum has died off I'm not even looking to trade NK again. GL
Experience... on the 22nd NK reached a 5 year high. If you're under the impression that charts go straight up you're sadly mistaken.
And that pull back to the high $13 was how I felt at the time of writing.
A year ago in November NK was trading near a buck and just finished a 20 fold run to near $20? At this point now that the momentum has died off I'm not even looking to trade NK again. GL
why? what evidence do you offer to back that up?
* * $NK Video Chart 12-22-2020 * *
Link to Video - click here to watch the technical chart video
Missed it. Anything material?
Wonder how clays shorters are doing?
CEO ON MSNBC NOW
* * $NK Video Chart 12-21-2020 * *
Link to Video - click here to watch the technical chart video
News will launch NK! BUT
I suspect not until institutions push out all of the retailers
then make them chase it. It's what they do.
NK could reach the Nov 2015 highs just under $20! I'm still out but if you're in this could run another $2 easy!
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Shs Outstand | 98.47M |
Shs Float | 28.16M |
Debt/Eq | 0.00 |
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