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Icanic Brands Co. Inc. (ICNAF)

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Last Post: 4/26/2021 10:23:25 AM - Followers: 31 - Board type: Free - Posts Today: 0

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Over the last three decades, intraoral dosage forms have been evolving as an acceptable and in some cases as the preferred, alternative to conventional tablets and capsules. Among them, Oral sprays are the fastest, most effective and comfortable way to take medicines, nutrients, minerals and vitamins. They have been acquiring important position in the market by overcoming previously encountered administration problems and contributing to extension of patent life.

Oral sprays have the unique property of rapidly releasing the drug in the oral cavity, thus obviating the requirement of water during administration. Therefore, these dosage forms have lured the market for a certain section of the patient population which includes dysphagic, bed ridden, and psychic, geriatric patients. This article focuses on the transmucosal view , spray formulation aspects , advances made so far in the field oral sprays and patented technologies.



Abstract: Nitroglycerin (glyceryl trinitrate, CAS 55-63-0, NTG) administered with an oral spray may be more effective in relieving anginal pain than sublingual tablets especially when the patient’s mouth is dry. In this study, the effect of a NTG oral spray (Myocor Spray) on exercise-induced angina was compared with that of a sublingual tablet in relation to the oral dryness. In 17 patients with effort angina, graded bicycle exercise was performed twice at an interval of one week.

Exercise was discontinued upon the onset of moderate anginal pain. Immediately after exercise, the oral dryness was evaluated by touching the tip of the tongue with a blotting paper for a moment. Then, 0.3 mg of NTG was administered by either a squirt of spray or a sublingual tablet in a randomized crossover fashion. Exercise results were reproducible between two exercise tests. According to the extent of the wet area of the blotting paper, the subjects were divided into two groups.

In 7 patients of the wet group, the remission times of chest pain and ST segment depression were not significantly different by the formulation of NTG. In 10 patients of the dry group, however, both chest pain and ST depression more rapidly recovered with use of the oral spray (p < 0.05 and p < 0.05, respectively). These results strongly suggest that the NTG oral spray is superior to the sublingual tablet in relieving anginal attacks, when the oral wetness is decreased.


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ICNAF News: Icanic Brands Company Inc. reports FQ2 results 04/06/2021 07:41:24 AM
#320   Month of consolidation at least from here, could StockLogistics 04/26/21 10:23:25 AM
#319   For years i have bought stock as a cheesebag 03/12/21 09:57:47 AM
#318   I just want to point out to new JeffElmo 03/02/21 10:04:35 PM
#317   New DD JeffElmo 03/02/21 10:01:02 PM
#316   “Cannabis 2.0”: CEO’s of Aphria, Icanic Brands, Curaleaf, lithiumjr 11/06/20 10:04:40 AM
#315   yesterday's interview with Brandon Kou, CEO of Icanic lithiumjr 11/05/20 10:26:01 AM
#314   Large Scale Automation Comes to Cannabis lithiumjr 11/03/20 08:42:25 AM
#313   Love this news! shigtynodigty 11/02/20 12:33:30 PM
#312   Mass Automation Lowering Costs for ICANIC BRANDS (CSE: makingmoneynow 10/31/20 01:06:58 PM
#311   Integrated Cannabis Company Inc. changed to Icanic Brands Renee 02/18/20 04:51:37 PM
#310   Will These Pot Stock Exceed Expectations? jonny_red 11/04/19 02:41:53 PM
#309   ICNAF Daily Chart Golden_Cross 10/08/19 03:58:20 AM
#308   News - Integrated Cannabis’ Ganja Gold Announces California Golden_Cross 10/08/19 03:56:43 AM
#307   Integrated Cannabis’ Ganja Gold is the Top Infused makingmoneynow 09/19/19 11:25:30 PM
#306   These Pot Stocks Are Ready for Some Upward jonny_red 09/06/19 08:17:12 AM
#304   WTF???????? Is this even a business? Buysomemore 05/09/19 12:30:51 PM
#303   Nice to see movement. I can't find any TheDalaiLama 03/20/19 12:58:13 PM
#302   ICNAF buy 0.3698 stocktrademan 01/11/19 12:42:52 PM
#301   Lol, and how is that working for you? Etailer 12/31/18 11:28:31 PM
#300   What happened here? Buysomemore 12/26/18 08:12:50 AM
#299   Any convertible debt here? d0lphint0m 12/03/18 09:15:42 AM
#298   Terratech still bites Etailer 11/18/18 01:20:53 PM
#297   After the earnings report tomorrow...argue some more bro. badbass58 11/18/18 12:26:48 PM
#296   Where did ICNAF rank? Oh wait.....they did not badbass58 11/18/18 12:25:13 PM
#295   Trulieve #1 badbass58 11/18/18 11:50:18 AM
#294   Argue with this bro. badbass58 11/18/18 11:49:03 AM
#293   Lol, TRTC should have thought about opening dispensaries Etailer 11/11/18 12:16:49 PM
#292   They have been adding dispensaries left and right. badbass58 11/11/18 12:12:36 PM
#291   Lol, is this some kind of joke? Etailer 11/09/18 09:12:03 AM
#290   Integrated Cannabis Company, Inc. Signs Definitive Agreement with PotterBanker 11/07/18 08:52:46 AM
#289   TCNNF. Now there a real legimiate company. badbass58 11/06/18 09:41:35 AM
#288   Look at what their doing. Pump and dump, investorpro1 11/06/18 06:42:37 AM
#287   ZZZZZzzzzzzZZZZzzzz. The pump and dump promoters for badbass58 11/06/18 05:10:22 AM
#286   100 % agree simmons420 11/03/18 11:29:40 AM
#285   Lol, ya, right. See you should get out. Lol investorpro1 11/01/18 08:28:58 PM
#284   ICNAF ~~~~>keep watching lol PotterBanker 11/01/18 10:55:39 AM
#283   haha, go ICNAF....Boom! greenwillow 10/31/18 11:39:45 AM
#282   keep watching. lol PotterBanker 10/31/18 11:37:44 AM
#281   No, just someone saying an RS. No way.. investorpro1 10/30/18 08:50:05 PM
#280   RS? Was there mention of an RS? PotterBanker 10/30/18 02:50:50 PM
#279   No way in hell a reverse split. If investorpro1 10/30/18 02:47:23 PM
#278   No way in hell a reverse split. If investorpro1 10/30/18 02:47:22 PM
#277   keep watching. lol PotterBanker 10/30/18 12:06:15 PM
#276   scam...lol greenwillow 10/30/18 12:04:09 PM
#275   those .55's already looking good PotterBanker 10/30/18 11:59:46 AM
#274   OS 36,300,559 MCAP 20,691,318 Revs coming soon: PotterBanker 10/30/18 11:58:22 AM
#273   Impacto better load up more before it hits badbass58 10/30/18 11:40:51 AM
#272   Impacto better load up more before it hits badbass58 10/30/18 11:40:49 AM
#271   right back to where it was before mostly...scam greenwillow 10/30/18 11:28:24 AM
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