Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.
http://www.ipharminc.com/press-release/2020/9/15/laboratory-testing-of-brilacidin-for-covid-19-in-combination-with-remdesivir-reduces-viral-load-by-nearly-100-percent
http://www.ipharminc.com/press-release/2021/10/25/innovation-pharmaceuticals-covid-19-clinical-trial-topline-results-anticipated-to-be-reported-the-week-of-november-8th
Be careful with this, the clock runs fast, pay attention to the week of November 8 or even earlier
Mick, I think we are the only ones watching GILD on iHub, whatever.
I bought more, could have bought better, but what the hay, I feel the sell off was uncalled for on dividend alone, we beat on earning as well as revenues, I believe investors wanted to know why Trodelvy results weren't part of the call, O'Day gave his reasons, he had to be political correct, plus what he said may very well be true; however, the FDA was never efficient but with Covid, they were working remote, hell, they hardly worked when they were at the office, plus, a lot of resources went to studying Covid itself as well as vaccination drugs. That's my nickel take on what's going on, here's what O'Day said.
Gilead CEO Dan O'Day says the delay isn't concerning, and is common in studies that require a certain number of patients to have their cancer worsen before data are analyzed. "Nothing has changed concerning our confidence" in the study's outcome, O'Day says. The delay could be a good sign, assuming Trodelvy patients are taking longer than expected to have their disease worsen. But RBC warns it could also be the control chemotherapy group causing the delay. Trodelvy had 3Q sales of $101M, in line with analyst projections. Trodelvy's sales are projected to be $689M in 2022, and to reach $2.1B in annual sales in 2025.
Gilead Sciences Inc (GILD)
65.92 ? -0.85 (-1.27%)
Volume: 5,723,324 @10/28/21 4:55:20 PM EDT
Bid Ask Day's Range
65.8 65.95 66.67 - 67.66
GILD Detailed Quote
5PM, we'll see how close you are, I'm hoping you're a tab low.
$gild should be over $80 to $100 imho
Gilead Sciences Inc (GILD)
68.25 ? 0.11 (0.16%)
Volume: 4,259,030 @10/08/21 6:48:20 PM EDT
Bid Ask Day's Range
67.8 68.25 67.82 - 68.41
GILD Detailed Quote
$gild should be over $80 to $100 imho
Gilead Sciences Inc (GILD)
68.25 ? 0.11 (0.16%)
Volume: 4,259,030 @10/08/21 6:48:20 PM EDT
Bid Ask Day's Range
67.8 68.25 67.82 - 68.41
GILD Detailed Quote
Gilead Sciences Inc (GILD)
71.67 ? -0.06 (-0.08%)
Volume: 6,556,960 @09/22/21 7:57:21 PM EDT
Bid Ask Day's Range
71.41 71.71 71.085 - 72.18
GILD Detailed Quote
NNVC encapsulates GILD’s Remdesivir, in what seems to be a proprietary formulation, and finds it remains intact longer, and works better, in Covid-19 treatment. Animal study reported by TDA news.
north, This is all on Fauci - proving all the lies used against 45 and "anecdotal" use of Hydroxychloroquine saving Covid-19 patients.
In the end it were all about money - and Remdesivir were in the middle of the bedrail. Right from the start Chinese came out and said Remdesivir didn't stop the infection - still it was approved for treating Covid patients by FDA - while HCQ at the same time were banned from use.
https://www.thegatewaypundit.com/2020/08/jail-fauci-us-almost-30-times-covid-19-deaths-per-population-third-world-countries-promoted-early-hcq-use/
European study finds that Gilead's Covid-19 antiviral remdesivir shows no clinical benefit
September 17, 2021 07:29 AM EDTUpdated 08:17 AM Coronavirus
European study finds that Gilead's Covid-19 antiviral remdesivir shows no clinical benefit
Nicole DeFeudis
Editor
Gilead’s remdesivir — or Veklury, as it’s marketed in the US — raked in around $2.8 billion last year as the only FDA-approved antiviral to treat Covid-19. But new data from a European study suggest the drug, which has been given to about half of hospitalized Covid patients in the country, has no actual benefit.
The open-label DisCoVeRy trial enrolled Covid-19 patients across 48 sites in Europe to test a handful of treatments, including remdesivir, lopinavir–ritonavir, lopinavir–ritonavir and interferon beta-1a, and hydroxychloroquine. To participate, patients had to show symptoms for seven days and require oxygen support. A total of 429 patients were randomized to receive remdesivir plus standard of care, while 428 were assigned to standard of care alone.
Researchers measured remdesivir’s efficacy on day 15, using the World Health Organization’s seven-point scale — only to find that no clinical benefit was observed in patients who received the drug over those who got standard of care alone. And while previous studies have linked remdesivir to a faster time to recovery, that result was not seen in the DisCoVeRy trial.
Here’s how patients were distributed on the WHO’s scale:
Not hospitalised, no limitations on activities (61 [15%] of 414 in the remdesivir group vs 73 [17%] of 418 in the control group); (2) not hospitalised, limitation on activities (129 [31%] vs 132 [32%]); (3) hospitalised, not requiring supplemental oxygen (50 [12%] vs 29 [7%]); (4) hospitalised, requiring supplemental oxygen (76 [18%] vs 67 [16%]); (5) hospitalised, on non-invasive ventilation or high flow oxygen devices (15 [4%] vs 14 [3%]); (6) hospitalised, on invasive mechanical ventilation or extracorporeal membrane oxygenation (62 [15%] vs 79 [19%]); (7) death (21 [5%] vs 24 [6%]).
The results bring into question Veklury’s approval — and also its hefty $3,000-plus price tag.
The FDA granted remdesivir full approval back in October based on three randomized control studies, including the full data from the NIAID-sponsored Phase III ACTT-1 trial published on Oct. 8, according to Gilead. That study showed a reduction in recovery time by five days in hospitalized Covid-19 patients and by seven days in patients requiring oxygen.
Gilead had previously been granted a partial EUA in early May to treat severe Covid-19, which was later expanded in August to include all hospitalized adults and children after a Gilead-led study showed modest efficacy.
But the week before remdesivir was approved, the WHO released a study showing the antiviral had no substantial effect on improving mortality rates, reducing the amount of patients needing ventilators or shortening hospital stays. In this trial, remdesivir had no material effects on ventilation initiation or time to discharge.
In an FAQ, the FDA had said that since Gilead’s ACTT-1 study was randomized, double-blinded and placebo-controlled (whereas the WHO trial was open-label), they found ACTT-1 to be “better suited” in a time to recovery endpoint.
In April, Gilead CEO Dan O’Day said about half of all hospitalized patients with Covid-19 in the US are treated with Veklury.
For a look at all Endpoints News coronavirus stories, check out our special news channel.
Oral version of Gilead's remdesivir demonstrates promising preclinical results
Sep. 15, 2021 8:29 AM ETGilead Sciences, Inc. (GILD)Merck & Co., Inc. (MRK)By: Jonathan M Block, SA News Editor5 Comments
Pack of Remdesivir pills
AlexSava/E+ via Getty Images
An oral version of a prodrug of the parental nucleoside of Gilead's (NASDAQ:GILD) antiviral remdesivir showed promise in a preclinical study.
The prodrug, GS-621763, demonstrated antiviral activity both in lung cell lines and in mice infected with SARS-CoV-2, according to results published in bioRxiv. The results have yet to be peer reviewed.
GS-621763 was also compared against molnupiravir, Merck's (NYSE:MRK) oral antiviral that the company expects will receive Emergency Use Authorization for COVID-19 by the end of the year, and both drugs had similar efficacy.
In the U.S., Veklury (remdesivir) is indicated for adults and children 12 years of age and older for the treatment of COVID-19 requiring hospitalization.
Now Read: Gilead: Fundamentals With A Booster Shot
I BELIEVE GILD is working with MTNB on this.
https://finance.yahoo.com/news/gilead-sciences-wins-reversal-1-154757453.html
"... A U.S. appeals court on Thursday threw out a $1.2 billion ruling against Gilead Sciences Inc, finding a patent on a cancer therapy it was accused of infringing was invalid, in a blow to rival Bristol Myers Squibb Co.
The two companies have been embroiled in a case involving accusations that Yescarta, the CAR-T cell cancer immunotherapy from Gilead's Kite Pharma unit, infringed on a patent for a similar therapy from Bristol's Juno Therapeutics.
Last year, a federal judge increased the damages from a jury trial and ordered Gilead to pay Bristol Myers $1.2 billion in the patent infringement case. The ruling on Thursday by the U.S. Court of Appeals for the Federal Circuit reversed the decision.
Bristol Myers in a statement said it disagreed with latest ruling and would seek a review of the Federal Circuit’s decision."
http://www.cafc.uscourts.gov/sites/default/files/opinions-orders/20-1758.OPINION.8-26-2021_1825257.pdf
Gilead Sciences Inc (GILD)
71.16 ? 0.28 (0.40%)
Volume: 4,361,771 @08/13/21 7:42:04 PM EDT
Bid Ask Day's Range
71.1 71.16 70.76 - 71.39
GILD Detailed Quote
Gilead Sciences Inc (GILD)
68.1 ? 0.41 (0.61%)
Volume: 6,419,563 @07/09/21 6:39:18 PM EDT
Bid Ask Day's Range
68.02 68.44 67.454 - 68.41
GILD Detailed Quote
Gilead Sciences Inc (GILD)
66.1543 ? -0.0757 (-0.11%)
Volume: 2,473,973 @05/26/21 11:55:31 AM EDT
Bid Ask Day's Range
66.15 66.16 65.55 - 66.225
GILD Detailed Quote
Is GILD's remdesivir relevant to this COVID-19 Vascular MOA? Amarin's Vascepa could be:
https://scitechdaily.com/covid-19-is-a-vascular-disease-coronavirus-spike-protein-attacks-vascular-system-on-a-cellular-level/
SALK Institute and NIH research report
DOI: 10.1161/CIRCRESAHA.121.318902
https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.318902
The tested cocktails still require (intravenous) remdesivir to stop SARS-CoV-2 replication. What's badly needed is an all-oral regimen.
Add some of this.https://www.sciencedaily.com/releases/2021/04/210427113805.htm
Another step in the right direction:
https://www.fdanews.com/articles/202455-advocacy-group-calls-for-rescinding-remdesivirs-approval-as-covid-19-treatment
More news about Redemsideath’s suspension:
https://www.reuters.com/article/us-health-coronavirus-remdesivir-who-sus-idUKKBN2801MU
Time to call Dr. Faucci to come to the rescue?
News from India regarding Redemsivdeath:
https://www.indiatoday.in/coronavirus-outbreak/story/who-suspends-remdesivir-from-list-of-medicines-1742697-2020-11-20
Gilead Sciences Inc (GILD)
66.87 ? 1.1 (1.67%)
Volume: 7,789,761 @04/16/21 7:59:31 PM EDT
Bid Ask Day's Range
60.55 68.6 65.965 - 67.08
GILD Detailed Quote
GILD Investor Relations
http://investors.gilead.com/events?c=69964&p=irol-calendar
Viral Disease Pipeline Phase 1 Phase 2 Phase 3 NDA/BLA/MAA HIV Biktarvy HIV treatment pediatric1 Capsid inhibitor (GS-6207)
HIV HTE HIV treatment naïve Vesatolimod (GS-9620, TLR-7 agonist) HIV cure Elipovimab (GS-9722, bNAb)
HIV cure HBV Selgantolimod
(GS-9688,TLR-8 agonist) HBV cure PD-L1 inhibitor (GS-4224) HBV cure 1 Biktarvy HIV treatment pediatric label extension.
2 Registrational for heavily treatment-experienced (HTE) patients.
http://investors.gilead.com/stock-information/stock-quote-chart
http://investors.gilead.com/stock-information/historical-price-lookup
News from India:
https://news.yahoo.com/india-bans-exports-remdesivir-drug-044405093.html
The Remdesivdeath gig is up. There are better options...
Humanigen Reports Positive Phase 3 Topline Results Demonstrating That Lenzilumab™ Improves Survival Without Need for Mechanical Ventilation in Hospitalized Patients With COVID-19
Lenzilumab improved the relative likelihood of survival without need for invasive mechanical ventilation (IMV) by 54%, achieving the primary endpoint of the Phase 3 study
Clinical improvement was observed over and above other treatments, including steroids and/or remdesivir
BURLINGAME, Calif.--(BUSINESS WIRE)-- Humanigen, Inc. (Nasdaq: HGEN) (“Humanigen”), a clinical-stage biopharmaceutical company focused on preventing and treating an immune hyper-response called ‘cytokine storm’ with its lead drug candidate, lenzilumab, today announced positive topline results from its Phase 3 clinical trial evaluating the efficacy and safety of lenzilumab in patients hospitalized with COVID-19. Trial results showed that patients who received lenzilumab and other treatments, including steroids and/or remdesivir, had a 54% greater relative likelihood of survival without the need for IMV compared with patients receiving placebo and other treatments. These results are statistically significant.
This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20210329005301/en/
$gild $64.46 ^ 0.38 (0.59%)
Volume: 15,231,389 @03/19/21 5:59:44 PM EDT
There are good/very good treatments but not yet FDA approved for covid 19
It are not vaccines but one vaccine ( Astrazeneca) that are on hold but not cancelled. in Europe
Covid-No good treatments after 1 year?
Nothing but vaccines that are getting cancelled all over Europe. And those that aren't, how long do they last? A few months/weeks??
Meanwhile, crisis mode in Brazil as Brazilians begging for a treatment that works.
Brazil plunges into deadliest chapter of it's pandemic
March 13, 2021
https://www.theguardian.com/world/2021/mar/13/brazil-covid-coronavirus-deaths-cases-bolsonaro-lula
Except for GILD, all 2 dozen or so of my investments have gains so far today. That is , except for SDOW, which is a little crash insurance in my portfolio.
GILD has been a long hold that has gone nowhere for a few years for me. I guess I'll sell it when it finally rallies a little. Their culture is a little too woke for me anyway. I mean, some social conscience is a good thing, but one can go too far.
Gilead Sciences Completes Acquisition of MYR GmbH
https://ih.advfn.com/stock-market/NASDAQ/gilead-sciences-GILD/stock-news/84499688/gilead-sciences-completes-acquisition-of-myr-gmbh
The Gild price is dropping recently. It has a lot of good news as you posted and 3/5/2021, FDA will have a meeting to discussion of the drug ( Axicabtagene ciloleucel ) for Getting Label Expansion For Cell-Therapy to Treat Lymphoma. Is some thing wrong?
https://www.mdpi.com/1999-4915/13/2/271
maybe a partnership would be "necessary"?
http://www.ipharminc.com/press-release/2021/3/2/innovation-pharmaceuticals-announces-publication-of-peer-reviewed-scientific-article-in-the-journal-viruses-on-the-anti-sars-cov-2-properties-of-brilacidin
http://www.ipharminc.com/press-release/2021/2/26/innovation-pharma-provides-study-details-for-ongoing-phase-2-clinical-trial-of-brilacidin-in-hospitalized-covid-19-patients
Gilead Sciences Inc (GILD)
64.38 ? -0.85 (-1.30%)
Volume: 6,054,624 @02/19/21 7:59:23 PM EST
Bid Ask Day's Range
64.38 64.72 64.27 - 65.22
GILD Detailed Quote
$gild $64.38 v -0.85 (-1.30%)
Volume: 6,052,396 @02/19/21 6:25:34 PM EST
GILD was hash tagged by our COO on Twitter and new development points us toward ur direction. Hopefully, GILD takes down their previous partner and tamiflu with ENZC ITV-1. Just a thought and my opinion.
$enzc. $GILD investors. You might want to check out this PR today. From googling found that tamiflu used to be owned by @Gilead until some bad blood. Key here is our drug was tested against tamiflu and was 20x less toxic with same efficacy. #payback maybe? https://t.co/yixxbz7EgL
— SimbaJ22 (@SimbaJ22) February 16, 2021
Little chance of that
Let me know when it gets under $60.
In November 2019, Dew Diligence posted the following on the BT Value board about a GILD/Amarin "collaboration":
"Quote:
…GILD added Vascepa to NASH trial…
An earlier article in streetinsider.com was guilty of suggesting that GILD had some kind of partnership with AMRN, so an updated article was posted to rebut this notion:
https://www.streetinsider.com/Analyst+Comments/Amarin+%28AMRN%29+Smacked+on+Bearish+Call%2C+But+Gilead+%28GILD%29+Adding+Vascepa+to+its+NASH+Combo+Raises+Eyebrows/16159446.html
Quote:
A recent posting at clinicaltrials.gov, pointed out by Raymond James' Gilead analyst Steven Seedhouse, showed that a cohort was added to the protocol that includes Amarin's Vascepa along with firsocostat (ACC inhibitor) and cilofexor (FXR agonist).
The analyst thinks Vascepa was added to compensate for the increase in TGs caused by firsocostat. He said this is similar to how statins compensate for LDL-C increase by FXR agonists.
Seedhouse said he is not aware of any formal collaboration between Amarin and Gilead, so he presumes Gilead is purchasing drug material."
I am trying to obtain any news of what has happened with respect to results from the added Vascepa mentioned in the above-quoted material. Comments from anyone with specific knowledge would be appreciated. Our portfolios contain both GILD and AMRN.
The FDA approved Vascepa for reducing the risk from various aspects of CVDs last December 2020.
See also:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=155960148
Remdesevir has FDA approval! Check your facts before spamming another board for a different play.
With as many doses that have been produced and ordered by the world by Gilead's extensive production network, it will take years for your B to ramp up and see meaningful revenue results when comparing the 2.
Having said that, I am a buyer of I*** based on Ph 2 results which have not been announced to have started yet, only plans to start. Initial dosing would be something to put out and that was supposed to have happened last week.
https://www.fda.gov/news-events/press-announcements/fda-approves-first-treatment-covid-19
Gilead’s Remdesivir AKA Velkury has emergency use authorization (EUA) n the United States and just barely reduces hospital length of stay in some patients and it is questionable if it really reduces mortality to any degree. It has NOT received FDA approval because it hasn’t performed in real life practice. As soon as the FDA sees another drug that can reduce length of stay and save some lives, Remdesivir will lose it’s EUA and it’s share of the market which is pretty much all of it.
Remdesivir needs Brilacidin, but it is abundantly clear that Brilacidin does not need Remdesivir. I anticipate the placebos will be whatever the standard of care is being used in the respective country as it is unethical to withhold treatment in a life or death situation. Brilacidin will go head to head vs. Remdesivir and we all know who will win.
Efftiabdunnsunnylemonturds!
Followers
|
165
|
Posters
|
|
Posts (Today)
|
0
|
Posts (Total)
|
4867
|
Created
|
04/30/09
|
Type
|
Free
|
Moderators |
333 Lakeside Drive
Foster City, CA 94404
PER IHUB MGMT |
02-07-2021
DISCLAIMER: ONLY FOR MICK
https://investorshub.advfn.com/boards/profilea.aspx?user=1012
*The Board Monitor and herewithin , are not licensed brokers and assume NO responsibility for actions,
investments,decisions, or messages posted on this forum.
CONTENT ON THIS FORUM SHOULD NOT BE CONSIDERED ADVISORY NOR SOLICITATION
AUTHORS MAY HAVE BUYS OR SELLS WITH THE COMPANIES MENTIONED IN TRADING POSTERS SHOULD DUE DILIGENT BUYING OR SELLING.
ALL POSTING SHOULD BE CONSIDERED FOR INFORMATION ONLY. WE DO NOT RECOMMEND ANYONE BUY OR SELL ANY SECURITIES POSTED HEREWITHIN.
ANY trade entered into risks the possibility of losing the funds invested.
• There are no guarantees when buying or selling any security.Any
Volume | |
Day Range: | |
Bid Price | |
Ask Price | |
Last Trade Time: |