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Generex Biotechnology Corp. (GNBT)

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Last Post: 12/12/2018 2:21:49 AM - Followers: 220 - Board type: Free - Posts Today: 1


Welcome to Generex

Generex Biotechnology Corporation is engaged in the research, development, and commercialization of drug delivery systems and technologies. Generex has developed a proprietary platform technology for the delivery of drugs into the human body through the oral cavity (with no deposit in the lungs). The Company's proprietary liquid formulations allow drugs typically administered by injection to be absorbed into the body by the lining of the inner mouth using the Company's proprietary RapidMist™ device. The Company's buccal insulin spray product, Generex Oral-lyn™ is in Phase III clinical trials at several sites around the world.

Antigen Express, Inc. is a wholly owned subsidiary of Generex. The core platform technologies of Antigen Express comprise immunotherapeutic vaccines for the treatment of malignant, infectious, allergic, and autoimmune diseases. Antigen Express has pioneered the use of specific CD4+ T helper stimulation in immunotherapy. One of its platform technologies relies on inhibition of expression of the Ii protein. Antigen Express scientists, and others, have shown clearly that suppression of expression of the Ii protein in cancer cells allows for potent stimulation of T helper cells and prevents the further growth of cancer cells. For more information about Antigen Express visit

Mission Statement

Our mission is to develop innovative drug delivery technologies and drugs that will improve the quality
of life for people who suffer from disease.

Management Team

Mark Fletcher
President & Chief Executive Officer

Mark Fletcher, Esq. Mr. Fletcher was appointed as President and Chief Executive Officer in March 2011 and has served and continues to serve as Secretary since September 2010 and as General Counsel since April 2003.  Mr. Fletcher was appointed as Interim President/Chief Executive Officer and Secretary in September 2010.  In April 2003, he took the position of Executive Vice President and General Counsel with Generex.  From October 2001 to March 2003, Mr. Fletcher was engaged in the private practice of law as a partner at Goodman and Carr LLP, a leading Toronto law firm. From March 1993 to September 2001, Mr. Fletcher was a partner at Brans, Lehun, Baldwin LLP, a law firm in Toronto. Mr. Fletcher received his LL.B. from the University of Western Ontario in 1989 and was admitted to the Ontario Bar in 1991.  The Board believes that Mr. Fletcher's wide-ranging legal knowledge and extensive experience as a practicing lawyer, combined with his managerial skills and business acumen and judgment, provide our Board with valuable legal and operational expertise and leadership skills.
Dr. David Brusegard Ph.D
Chief Operating Officer (COO)

Dr. Brusegard has a breadth of experience in several fields of endeavour including, medical record design, health informatics, health insurance, digital mapping, database design, global positioning systems applications, business management and strategic planning. He was a senior economist at Statistics Canada for a decade, an adjunct professor at the University of Toronto and taught information ethics and information law at Ryerson University. He has consulted internationally on information management for the World Bank as well as major consumer packaged goods companies, hospitals, municipalities, and all levels of government. Recent positions of note include; Vice President, Analytics for ICOM Communication and Information, President of Geographic Decision Support Systems, CEO, Tristar Software, and CEO of the Pentius Group (a 5 company health insurance and managed care portfolio).

Dr. Brusegard's graduate work was carried out at The University of North Carolina at Chapel Hill, and the University of Calgary from which he holds a Ph.D. Phil.

Stephen Fellows
Acting Chief Financial Officer (CFO)

Mr. Fellows has over 20 years of experience in financial management and accounting reporting for both public and private companies, including debt and equity financings. As Acting Chief Financial Officer, he is instrumental in helping to direct and oversee Company financial and accounting procedures while providing strategic planning for creating future revenue streams including joint ventures and licensing arrangements for the Company's current portfolio of products as well as its product development pipeline.

Prior to joining Generex, Mr. Fellows spent almost four years at Sona Mobile Holdings Corporation, a publicly held software company which developed software applications for mobile devices, where he served as Chief Financial Officer. Mr. Fellows joined Sona Mobile from 3Com Corporation, where he was the Director of Finance of the corporate accounting group in Marlborough, MA. Prior to that, Mr. Fellows spent five years as the Director of Finance & Operations of 3Com's Canadian subsidiary. Mr. Fellows joined 3Com from Pennzoil Corporation where he spent time in the international mergers and acquisitions group in Houston, Texas, as well as four years as Controller for Pennzoil Canada.

Mr. Fellows holds a Bachelor of Business Administration degree from Wilfrid Laurier University in Waterloo, Ontario, Canada and earned his Chartered Accountants designation while articling with Arthur Andersen & Company in Toronto.

Dr. Eric von Hofe, Ph.D.
Vice-President of Generex and President of Antigen Express

Dr. Eric von Hofe, has been President of Antigen Express since April 2005. He joined Antigen in November 2003 as Vice President of Technology Development of Antigen. He has extensive experience with technology development projects, including his previous positions at Millennium Pharmaceuticals first as Program Director for Target Validation and later as Director of Programs & Operations, Discovery Research. Prior to that, Dr. von Hofe was Director, New Targets at Hybridon, Inc., where he coordinated in-house and collaborative research that critically validated gene targets for novel antisense medicines. Dr. von Hofe also held the position of Assistant Professor of Pharmacology at the University of Massachusetts Medical School, where he received a National Cancer Institute Career Development Award for defining mechanisms by which alkylating carcinogens create cancers. He received his Ph.D. from the University of Southern California in Experimental Pathology and was a postdoctoral fellow at both the University of Zurich and Harvard School of Public Health. His work has been published in forty-seven articles in peer-reviewed journals, and he has been an inventor on four patents.

Dr. Gerald Bernstein, M.D.
VP Medical Affairs

Gerald Bernstein,M.D., F.A.C.P. Graduated from Dartmouth College and Tufts University School of medicine. He is board certified in internal medicine (1966) and endocrinology and metabolism (1973). He entered practice in 1966 after completing a research fellowship. Dr. bernstein is an associate clinical professor at Albert Einstein College of Medicine in New York. He is an attending physician at Beth Israel Medical Center, Lenox Hill Hospital (1974) and Montefiore Medical Center (1966). He served on the National Board of Directors of the American Diabetes Association, its research foundation and many national committees. He was on the editorial board of the publication "Clinical Diabetes". He has been president of the New York Downstate affiliate of the American Diabetes Association. He is the author of many papers, clinical and scientific and the book "If it runs in your family: Diabetes Mellitus, Reducing your Risk". Dr. Bernstein is a past president of the American Diabetes Association and was Director of the Beth Israel Health Care Systems Diabetes Management Program. He is currently Director of the Diabetes Management Program of The Friedman Diabetes Institute at Beth Israel Hospital in New York. He has served as Vice President for Medical Affairs at Generex Biotechnology Corp. Since 2001.

Dr. Jaime Davidson, M.D.
Medical Director

Dr. Jaime Davidson, MD., F.A.C.P. was appointed a consultant Medical Director for Generex in July, 2006. Dr. Davidson is the President of Endocrine and Diabetes Associates of Texas, based at the Medical City Dallas Hospital complex, and a Clinical Associate Professor of Internal Medicine at University of Texas Southwestern Medical Center in Dallas, Texas. Dr. Davidson chaired the Diabetes Consensus Guidelines for the American College of Endocrinology and serves as Director of the Annual Intensive Diabetes, Endocrinology and Metabolic Diseases Course for the University of Southern California Keck School of Medicine. He serves as a council member for the Texas Department of Health Services, appointed by Texas Governor Rick Perry. In 2006 Dr. Davidson was distinguished by the American Association of Clinical Endocrinologists with an award for his contributions to the improvement of endocrine health for under-served populations, and by the American Diabetes Association with the Harold Rifkin MD award for his international contributions in the diabetes field. In the past, he has held positions with the National Diabetes Advisory Board, the National Institutes of Health, the Centers for Disease Control, the Institute of Medicine, and the boards of directors of the American Diabetes Association, the American Association of Clinical Endocrinologists, and the American College of Endocrinology. He served in higher education for a six year term as a Regent of Midwestern State University in Texas appointed by then Governor George W. Bush. He has also served in the President's Council for Fitness and Sports, chaired the Texas Diabetes Council of the Texas Department of Health for several years where he instituted the Texas Diabetes Algorithm, and under his guidance the Texas Diabetes Institute was established with the University of Texas Health Science Center in San Antonio, Texas. Dr. Davidson's experience in clinical pharmacology began with a Clinical Pharmacology Fellowship at Lilly Laboratories for Clinical Research and it continued with multiple clinical trials. In addition, he was an advisor to the Food and Drug Administration (FDA) on the Endocrinology and Metabolism Advisory Board. Dr. Davidson's Internal Medicine training was completed at Scott and White Hospital (now known as Texas A&M University) and his Endocrinology training at University Of Indiana.


Generex is currently conducting pre-clinical and human clinical trials using its proprietary technology platforms in the areas of diabetes, pain management and cancers.




Generex has two platform technologies in the area of drug delivery and immunomedicines.

Drug Delivery - RapidMist™:

Comprised of a proprietary device & pharmaceutical agents in an aerosolized liquid formulation.

Delivered through the buccal mucosa (inner cheek of mouth) and NOT THE LUNGS.

Applicable to most proteins and peptides.


Antigen Express technology focuses on modulating immune responses mediated by T helper (Th) cells, a class of lymphocytes that plays a multifaceted role in the immune system, both enhancing and suppressing immune responses. The cells are essential both for obtaining a robust and long lasting response against infectious agents or cancer cells and for down regulating immune responses when the immune system becomes inappropriately stimulated, e.g. in autoimmune disease and allergy.


Antigen Express

Antigen Express is a platform technology and product-based company developing proprietary vaccine formulations for active immunotherapy as well as disease prevention.

In contrast to traditional therapies, the goal of active immunotherapy is to amplify the patients' ability to fight specific disease rather than targeting the diseased tissue or pathogenic agent directly. The novel technologies being developed at Antigen Express allows for robust and antigen-specific stimulation of CD4+ T cells, a cell type critical in the recognition of pathogens and modulation of the immune response.

Antigen Express is developing these technologies for application to the treatment of cancer, infectious diseases, and other serious diseases. Our most advanced vaccine utilizes a self-potentiating peptide as an off-the-shelf product for active immunotherapy of breast and prostate cancer

To find out more on Antigen Express please go to


Eric von Hofe, PhD

Dr. von Hofe joined Antigen Express in November of 2003. Prior to this time he held two positions at Millennium Pharmaceuticals; first as Program Director for Target Validation, where he presided over technology development efforts for Aventis and Cereon, and second as Director of Programs and Operations, Discovery Research. He received his Ph.D. from the University of Southern California and was a postdoctoral fellow at the University Hospital of Zurich and Harvard. From 1989 to 1992 he was Assistant Professor of Pharmacology at the University of Massachusetts Medical School.

Robert E. Humphreys, MD, PhD
Founder (retired)

Dr. Humphreys was the Chief Scientific Officer of Antigen Express from it's inception, and at the time of his retirement held the position of Executive Vice President. Prior to joining Antigen Express, he was Professor of Pharmacology and Medicine, and interim Chair of Pharmacology at the University of Massachusetts Medical School. He received his BS, PhD and MD at Yale, and served in the US Navy at the US Naval Hospital and Naval Medical Research Institute in Bethesda. He was a postdoctoral fellow of Dr. Jack Strominger at Harvard. He has published over 140 peer-reviewed papers and has served 10 years on NIH study sections.

Catherine Blackwell
Business Operations Manager

Catherine Blackwell became a member of Antigen Express in January of 2004. She is responsible for managing the business operations of Antigen Express along with grants management and human resources. Preceding her position at Antigen Express, she was the project coordinator and accounting manager for Cyagra Incorporated, a biotechnology company specializing in agricultural cloning. She received her Bachelors degree in Veterinary Science in 1987 from the University of Massachusetts and a Masters degree in Education in 1991 from Anna Maria College.



Generex is dedicated to the research, development and commercialization of drugs delivery via the buccal mucosa. Generex seeks to out-license its RapidMist™ product programs and identify in-licensing opportunities and acquisitions in the areas of diabetes, drug delivery, cancer, H5 avian influenza, HIV, generic and branded prescription drugs, 505(b)2 product candidates, and late stage development opportunities.

Here are some of the companies we have partnered with; Please click on logos the get the details.

Medipharma S.A.

From its beginnings in 1982 Medipharma S.A. ( is dedicated to the development and pharmaceutical product elaboration for human consumption, taking quality as the basic premise. Thus its Productive facilities, Laboratory of Quality and Microbiological Control have evolved continuously according to the more outpost norms from quality assurance (GMP - Good Practices of Manufacture), always with constant efforts in Investigation and Development. Several of our products count on studies of bioavailability approved by the Argentine sanitary authorities. This action of almost three decades, has allowed us to enter like suppliers of all the great welfare centers of the country and more recently to strengthen in the ethical market. The laboratory of Quality Control counts on equipment that allows us to compliment with the international norms as far as analytical and microbiological controls. Our productive areas count on equipment and personnel that have distinguished us in the medicine production of high risk (low product concentration with dangerous pharmacologic limits, for example digoxin) Complimenting GMP 2002, our company has all its productive and control equipment qualificated as well as all its productive and cleaning processes validated (reviewed and approved by our national authorities in 2005). We have also signed agreements of Investigation and Development with the C.O.N.I.C.E.T. and the National University of La Plata, for the obtaining of active principles of last generation.  One of the research groups working on a calcium supplement directed to stimulate the passive absorption, independent of age and hormonal status of the patient, stimulating the gastrointestinal absorption of calcium through the formation of a micelle in situ transportable via passively into the bloodstream, independent of vitamin D and / or estrogen intake. This research is oriented towards the prevention and / or treatment of osteoporosis.  The other research group studies a new derivative of valproic acid molecule which by its molecular structure allows cross the blood-brain barrier. This new molecule will allow the health professional to manage a dosage regimen involving the administration to patients of up to 100 times lower dose of valproic acid, than those used with existing molecules, reducing the adverse effects associated with toxicity of the same.

Sanofi-aventis (, a leading global pharmaceutical company, discovers, develops and distributes therapeutic solutions to improve the lives of everyone. Sanofi-aventis is listed in Paris (EURONEXT: SAN) and in New York (NYSE: SNY).


Merck Serono

Merck Mexico ( was founded in 1930 as one of the first pharmaceutical producers in Mexico. Today, with close to 1,035 employees, Merck, S.A. de C.V. manufactures and sells a great variety of products for the treatment pain, diabetes, thyroid problems, colds, growth hormone, multiple sclerosis and cancer, among other diseases. In its chemical area, Merck has specialty pigments and active ingredients for the cosmetics industry.

Dong Sung Pharmaceuticals

Dong Sung Pharmaceuticals (, founded in 1957, is one of Korea's leading pharmaceutical companies with more than 500 employees and the largest production facilities in the country.


Catalent ( is a leading provider of advanced dose form and packaging technologies, and development, manufacturing, packaging and printing services for pharmaceutical, biotechnology and consumer healthcare companies in nearly 100 countries. Catalent applies its local market expertise and technical creativity to advance treatments, change markets and enhance patient outcomes. Catalent employs approximately 9,000 at 29 facilities worldwide and in fiscal 2010 generated more than $1.7 billion of annual revenue.

Adcock Ingram

Adcock Ingram (, part of the Tiger Brands Group, is a leading South African pharmaceutical company with an 11.4% share of the private healthcare market. Adcock Ingram has an extensive range of prescription, generic, and over-the-counter products and also provides life saving hospital equipment and diagnostic products and services.

Shreya Life Sciences Pvt

Shreya Life Sciences Pvt. Ltd. (, a leading Indian-based pharmaceutical company. Shreya is the fourth largest distributor of insulin in the Indian insulin product market with a compound annual growth rate of 38% (per C MARC market research). Shreya has interests in both pharmaceutical and biopharmaceutical products in key therapeutic segments including cardiology, neuropathy, and diabetes. The company has business operations in India, Russia, the Commonwealth of Independent States, and African countries. The parties are making arrangements for the expansion of extant production facilities to meet the anticipated demand for the product in India and other jurisdictions where governmental approvals are pending.

Investor Relations

For more information please contact:
Todd Falls
Tel: 1-800-391-6755
Fax: (647) 547-7104


OTC Bulletin Board

Listed Security

GNBT Common Stock

Transfer Agent

StockTrans, Inc.
44 West Lancaster Avenue
Ardmore, PA 19003
Phone 610-649-7300
Fax 610-649-7302

Corporate Counsel

Eckert Seamans Cherin & Mellott, LLC
1515 Market Street, 9th Floor
Philadelphia, PA 19102
Phone 215-851-8447
Fax 215-851-8383

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#7254   I don't own any of this stock, but JMC21 12/12/18 02:21:49 AM
#7253   If there has been fraud like you infer, OrlandoJohn 12/11/18 11:08:55 PM
#7252   Just reality,we are talking about serious business here, grobtekrebssvindl 12/11/18 10:40:34 PM
#7251 have had a negative perspective for whatever docj 12/11/18 07:03:53 PM
#7250   "80% this will go back" I told You grobtekrebssvindl 12/11/18 04:12:48 PM
#7249   Got me some more at .71 just now, birdys3333 12/11/18 04:00:31 PM
#7248   I did not get my dividends,like i said..duuuhhh grobtekrebssvindl 12/11/18 03:08:01 PM
#7247   Well if it makes you feel any better, birdys3333 12/11/18 02:16:36 PM
#7246   Like i said i did not care either,i grobtekrebssvindl 12/11/18 02:09:20 PM
#7245   Truthfully, I do very little dd, and could birdys3333 12/11/18 01:53:16 PM
#7243   Ok, my friend what ever you say, have birdys3333 12/11/18 11:30:22 AM
#7242   Yahoo:for some reasons more people,pumpers on yahoo.Some post grobtekrebssvindl 12/11/18 11:18:44 AM
#7240   Little advise, if you can not make money birdys3333 12/11/18 10:46:43 AM
#7239   what is this yahoo thing you keep talking myke2 12/11/18 10:34:10 AM
#7238   Beside the obvious,these people are psychopaths:no remorse,no guilty grobtekrebssvindl 12/11/18 10:11:16 AM
#7237   are you really into this company this is myke2 12/11/18 09:26:14 AM
#7236   Btw the IQ level of the company like grobtekrebssvindl 12/10/18 11:49:46 PM
#7235   Once again misinformation. First off the post by tc2000chartreader 12/10/18 10:45:14 PM
#7234   Since yahoo deleted this instant ,repeatedly ,let's see grobtekrebssvindl 12/10/18 09:17:20 PM
#7233   Yeah started to really suspect them when all gonetopot 12/10/18 09:11:54 PM
#7231   I could be the CEO here :o) grobtekrebssvindl 12/10/18 07:08:57 PM
#7230   Like i said i don't care it is grobtekrebssvindl 12/10/18 05:17:52 PM
#7229   "Everybody knows the stock will plummet below 50 grobtekrebssvindl 12/10/18 04:54:54 PM
#7228   Oh hey is that Joseph J Moscato out myke2 12/10/18 04:26:20 PM
#7227   dude are you new at buying stock? myke2 12/10/18 04:17:29 PM
#7226   You don’t see the thousand buy and ask cloudstrife 12/10/18 04:07:14 PM
#7225   Didn't see that last minute manipulation that has OrlandoJohn 12/10/18 04:01:34 PM
#7224   I threw a hundred to this scam I myke2 12/10/18 03:58:01 PM
#7223   Scam for sure and when I said 90 cloudstrife 12/10/18 03:49:41 PM
#7222   they have a sell dump point the can't myke2 12/10/18 03:46:12 PM
#7221   A whopping 5100 shares "were dumped" at .90. docj 12/10/18 03:34:35 PM
#7220   Here comes the manipulation thousand by thousand sales cloudstrife 12/10/18 03:27:23 PM
#7219   hey man are you in Orlando myke2 12/10/18 03:25:35 PM
#7218   Typical pump and dump they manipulate the stock cloudstrife 12/10/18 03:22:47 PM
#7217 OrlandoJohn 12/10/18 03:18:52 PM
#7216   Speaking of DD no company has anyone to myke2 12/10/18 03:18:17 PM
#7215   Pumped dumped now dead and crashing get out cloudstrife 12/10/18 03:09:28 PM
#7214   insiders this is a Pump and Dump scam!!! myke2 12/10/18 03:09:26 PM
#7213   Split good,Why people are saying grobtekrebssvindl 12/10/18 02:55:28 PM
#7212   the CEO has a PhD of spilling crap myke2 12/10/18 02:54:38 PM
#7211   not good for the shell company only good myke2 12/10/18 02:49:57 PM
#7210   this is a typical Pump and Dump stock myke2 12/10/18 02:48:25 PM
#7209   Why was the split good? Renegades17 12/10/18 02:45:59 PM
#7208   Well great the antigen website home page finally myke2 12/10/18 02:43:52 PM
#7207   GNBT#$$: Hey Bulba,like I said a week ago, jack7377 12/10/18 02:17:52 PM
#7206   It was a foreword split not dividends idk cloudstrife 12/10/18 02:03:29 PM
#7205   It was a split (what is good),but zero grobtekrebssvindl 12/10/18 01:58:11 PM
#7204   May as well have been a reverse split cloudstrife 12/10/18 01:46:55 PM
#7203   seems LIKE PEOPLE ARE SEELING GNBT TO BUY otced 12/10/18 01:46:20 PM
#7202   I found "disturbing" how some "shareholders" desperately grobtekrebssvindl 12/10/18 01:42:40 PM