ChromaDex Corp. (CDXC)

[tredenwater2]

Thanks I googled the same after posting.

[tredenwater2]

Thanks I googled the same after posting.

[bryanb40]

https://www.investopedia.com/terms/c/confidential-treatment-order.asp

[tredenwater2]

Anybody know what a confidential treatment order is and why this company is using one? Long haul for shareholders and all they can produce is a CTO?

[whytestocks]

JUST IN: $CDXC ChromaDex Announces Study Results Showing Nutritional Protocol Including Nicotinamide Riboside Plus Standard of Care Reduces Recovery Time in COVID-19 Patients by Nearly 30%

Phase 2 study finds addition of nutritional protocol to standard of care reduces recovery time to 6.6 days from 9.3 in mild-to-moderate COVID-19 patients ChromaDex Corp. (NASDAQ:CDXC) today announced that results from the study “Combined metabolic cofactor supplementa...

In case you are interested CDXC - ChromaDex Announces Study Results Showing Nutritional Protocol Including Nicotinamide Riboside Plus Standard of Care Reduces Recovery Time in COVID-19 Patients by Nearly 30%

[weasel4339]

Wakey wakey

[tredenwater2]

Absolutely amazing this message board has dried up as soon as the lawsuit is over. Price has also stabilized....hmmmm!

Oan my wife said she just saw a true niagen commercial on a network tv channel. Just a matter of time until this company gets bought out. Will Dr Frost and Nane Hasaio let this happen or will OPKO “absorb” Chromadex?

Tred

[Monroe1]

thanks for sharing. Good info good research.

[Milarepa]

Oral Argument Before CAFC on Elysium's Claim:
This morning Elysium got to argue its case on Claim 2 of the '086 Patent before the Court of Appeals for Federal Circuit. It didn't go great for Elysium.
https://www.right-of-assembly.org/post/oral-argument-before-the-cafc

[Southern Gal]

First-of-its-Kind Clinical Study Initiated to Investigate Potential Benefits of Nicotinamide Riboside Combined with Exercise in Older Adults with Hypertension

Study expands on recently published preclinical data that showed improvements in aerobic performance following supplementation with ChromaDex’s novel form of vitamin B3

LOS ANGELES, Jan. 06, 2020 (GLOBE NEWSWIRE) -- ChromaDex Corp. (CDXC), the global scientific authority on nicotinamide adenine dinucleotide (NAD) and nicotinamide riboside (NR) science, announced today the initiation of a first-of-its-kind Phase 1 clinical study sponsored by the University of Florida, in collaboration with the National Institute on Aging. This trial will assess the potential of NIAGEN® (NR) to enhance the effects of exercise therapy in older adults with hypertension. ChromaDex’s patent-protected NR is a unique form of vitamin B3 that is proven to safely increase NAD+ levels in the body. NAD+ declines as we age and is a critical coenzyme for cellular energy production and mitochondrial function, both important components of healthy human aging.

About one third of U.S. adults have hypertension, putting them at greater risk of cardiovascular disease, or even death. The benefits of exercise in helping to manage hypertension and enhance cardiovascular health are well documented. However, as individuals age, continuing a regular exercise routine can become more challenging due to age-associated physiological declines.

“This clinical trial will provide valuable information on the potential of NR supplementation to enhance the benefits of exercise in older populations with hypertension. Published data suggest NR may support cardiovascular health with further study, specifically through improvements in blood pressure (BP) and aortic stiffness. However, older hypertensive adults have yet to be explored in a clinical study,” said primary investigator Robert Mankowski, PhD, Department of Aging and Geriatric Research, the University of Florida.

This new randomized, double-blind study will evaluate the impact of NR supplementation combined with exercise in 74 hypertensive adults as measured by changes in arterial stiffness, blood pressure and walking performance. It was initiated as part of the ChromaDex External Research Program (CERP), where ChromaDex supplies its NR and placebo at no cost to research institutions worldwide.

“Through increases in NAD+, NR has the potential to improve cellular energy production, supplying individuals with the energy necessary to maintain a regular exercise routine,” said ChromaDex Chief Scientific Officer Dr. Matthew Roberts. “We look forward to enhancing our understanding of the use of NR as an adjuvant approach to exercise in promoting improvements in the cardiovascular health of aging adults.”

Niagen is the only commercially available nicotinamide riboside which has twice been successfully reviewed under FDA's new dietary ingredient (NDI) notification program and has also been successfully notified to the FDA as generally recognized as safe (GRAS).

[Wildbilly]

Management back to sales and not letting the legal dominate,

nice month so far. Accum/dist needs to continue heading up.

[ClayTrader]

* * $CDXC Video Chart 12-13-2019 * *

Link to Video - click here to watch the technical chart video

[Milarepa]

Here is ChromaDex's Supplemental Brief, spelling out in detail exactly how Elysium's misdeeds caused damages.

https://www.right-of-assembly.org/post/cdxc-s-supplemental-msj-brief

[Milarepa]

What you missed on Right of Assembly:

1. The identity of Elysium's First Mystery NR Supplier Revealed:
https://www.right-of-assembly.org/post/there-is-a-pattern-here-of-behavior

2. ChromaDex Asks to Restart the Patent Infringement Action in Delaware
https://www.right-of-assembly.org/post/chromadex-lift-the-stay-in-delaware

3. Might Elysium's Counsel Withdraw?
https://www.right-of-assembly.org/post/no-way-out-law-firm-edition

[GAB]

Strange, I ordered from the Wal-Mart app for a 30 day supply to be shipped by Tru-Niagen, but just got an e-mail that the order was cancelled with explanation.

[tat4tat]

Weak PPS response to analysts targets. The other day a target of 8 bucks was given and now a 6 bucks target. Great trading opportunities at between 3.71 and 2.82 recently. Will they miss earnings estimates?

[Milarepa]

Thanks! If people like to read it, then I like to write it. My intuition is that Oppenheimer's initiating coverage with an "outperform" recommendation ought to reassure a lot of investors.

[frrol]

Yet another fantastic blog entry. You really elucidate these arcane legal actions and the bigger picture. Keep it up, I find it fascinating as a non-attorney.

[Milarepa]

Trial Delay in California; should we even care?

https://www.right-of-assembly.org/single-post/2019/10/12/WTH-Just-Happened-INVESTORS-GUIDE-to-the-ChromaDex-Litigation

[jfk]

hope that is correct. based on stock action, seems no harm done. thanks

[Wildbilly]

Fried & Farr putting their own $ in since March

http://www.openinsider.com/search?q=cdxc

[Milarepa]

The consensus on the other board seems to be that this is the formal registration of the shares previously issued, which makes them eligible for sale, but does not necessarily evince an intent to sell (and if Li were bailing out we would indeed be alarmed!!!)

[jfk]

Can someone explain the 'private sale'. Is this an especially negative sale that the biggest holders want to dump their holdings in CDXC?

[Milarepa]

California Trial now October 22
https://www.right-of-assembly.org/single-post/2019/09/12/CA-Trial-Delayed-to-October-22

[Wildbilly]

Good get


AgeX ($AGE) CEO Dr. Michael West giving a basic primer on the science.

https://vimeo.com/357713085?ref=em-share

[Jitz]

future merger potential?

https://finance.yahoo.com/news/industry-leaders-aubrey-grey-frank-120000033.html

[Milarepa]

Will Elysium's Damages Expert Get to Testify?
https://www.right-of-assembly.org/single-post/2019/09/06/Cockburn-Testimony----Opposition-and-Reply-Briefs

[Milarepa]

CDXC Reply Brief: Cooley Picks Off a Runner
https://www.right-of-assembly.org/single-post/2019/09/04/CDXC-Reply-ISO-Motion-for-Summary-Judgment

[Milarepa]

Deposition of Elysium CEO Eric Marcotulli:
https://www.right-of-assembly.org/single-post/2019/09/01/The-Marcotulli-Deposition----Yikes

[Milarepa]

New Facts Emerge: the fullest account yet of the alleged trade secret thefts:
https://www.right-of-assembly.org/single-post/2019/08/31/OMG---ChromaDexs-Opposition-Brief-on-Summary-Judgment

[Milarepa]

CAFC Appeal Update: Boring

The PTAB appeal has turned boring; we’ll probably end up in the same place we are right now, with all of the ‘807 patent valid and Claim 2 of the ‘086 patent valid and that’s that.

https://www.right-of-assembly.org/single-post/2019/08/29/CDXC-Files-CAFC-Opposition-Abandons-Cross-Appeal

[Milarepa]

Evidence of bad behavior by Elysium's principals
(Marcotulli and Alminana) should be admitted into evidence
says ChromaDex
https://www.right-of-assembly.org/single-post/2019/08/28/Elysiums-Personal-Conduct-CDXC-Opposition-Brief

[Milarepa]

Analysis of Evidentiary (exclusion) Motions:

ChromaDex's Motions to Exclude Evidence:
https://www.right-of-assembly.org/single-post/2019/08/24/Analysis-of-ChromaDexs-Evidentiary-Motions

Elysium's Motions to Exclude Evidence:
https://www.right-of-assembly.org/single-post/2019/08/24/Analysis-of-Elysiums-Evidentiary-Motions

[jfk]

There is a ALS website, with forum discussions, ALS News Today, but not sure if they would welcome the mention of the study, and the use of TruNiagen. I will try to register there and see.
Probably similar sites for ALZ community as well.

[Milarepa]

Yes, I agree, for ALS for all we know any NAD precursor could make a positive difference, and the advantages of NR versus NAM may not be relevant, or may not apply at all. I wish that someone in the ALS community were plugged into the CDXC community, so we could monitor anecdotal evidence.

[jfk]

At least there appears to be something available NOW for ALS sufferers, individuals who otherwise have NO hope whatsoever. More study, certainly, and absolute proof required, surely, but if you have the disease, it is worth the try. No harm, no foul.

[Milarepa]

Or Nicotinamide should be megadosed. The study doesn't show that direct oral supplementation of NAM would be equivalent (but presumably it would) or that oral NR would do as well or better (although presumably it would). We could use some more research showing how the limits of NAM oral supplementation don't apply to NR oral supplementation.

[jfk]

ALS Remedy. Wow, Nature publication should be enough ammunition to demonstrate that TruNiagen should be mega-dosed by anyone suffering ALS to prolong their lives
https://www.weizmann-usa.org/news-media/in-the-news/major-study-shows-gut-microbes-may-impact-course-of-als?utm_source=2019-08-Enewsletter-Subscribers&utm_medium=email&utm_campaign=fy20enews

[Milarepa]

Summary Judgment Motions in California:
1. ChromaDex's Motion
https://www.right-of-assembly.org/single-post/2019/08/18/MSJ-Analysis-Part-1-ChromaDexs-Motion

2. Elysium's Motion
https://www.right-of-assembly.org/single-post/2019/08/20/MSJ-Analysis-Part-2-Elysiums-Motion

3. 150+ Evidentiary Exhibits
https://www.right-of-assembly.org/single-post/2019/08/16/Cross-Motions-for-Summary-Judgment

[Wildbilly]

After 2 years I'm starting to see some tangible changes.

Due to some conditions the last decade I used to nap on and off during the day, some involuntary. For the last two months I have no desire to nap and even when I want to my energy level won't allow it, mind all awhirl. My libido appears to be through the roof the last several weeks as well, hope that holds up.

[Milarepa]

New Summary: ChromaDex-Elysium Litigation
It took almost 9,000 words, but here is the best summary of the ChromaDex-Elysium litigation yet:
https://www.right-of-assembly.org/single-post/2019/08/01/Ultimate-Guide-to-the-Elysium-ChromaDex-Litigation----2019

[Wildbilly]

Scientific Reports: increases NAD 51% in two weeks with sustained use of 300 mg.

Consumption of 100, 300 and 1000?mg NR dose-dependently and significantly increased whole blood NAD+ (i.e., 22%, 51% and 142%) and other NAD+ metabolites within 2 weeks.

Largest clinical trial yet with 140 healthy overweight adults.

https://www.nature.com/articles/s41598-019-46120-z

[jfk]

Whole Foods, crack in the door in Canada. If in these 6 stores product movement proves out, then it launches in USA in 2020. Amazon movement must have justified this trial in Canadian stores. If they move 12 3/packs per week, that's approx. $98,000 per outlet. Assuming 624 yearly purchases, with the same buyers purchasing quarterly, or 624/4=156 unique Tru-Niagen consumers per Whole Foods outlet. About 500 stores in North America, that's $49M/year volume, at 35% Gross margin to CDXC (??), would drop $17M, figure net $10M Net Profit from this one customer. Could be very very interesting in 2H2020 in the USA, if the volumes prove out in Canada. Would open the door to Target, Costco, and some other higher end Grocery outlets as well. I hope they have a plan to juice the sales in Canada. If they can't get it going there, heads should roll in California. Will be interesting to see how they merchandise, ie. in a monthly, or 3-pack, or both. Anyone live in Canada??

[cantwate]

I got a promo from them this morning and asked about a way to measure NAD. This is the entire response.


Cheri Thomas (Tru Niagen)
Jul 17, 11:18 PDT

Hello,

Thank you for your email and interest in TRU NIAGEN®. While some scientists have developed methods to measure NAD+ levels for research, they have not yet translated these measurements from the laboratory bench to the clinic. At some point in the future, we expect the analytical method to be standardized so that NAD+ analysis can be introduced into clinical laboratory use. More work will be needed to bring this exciting technology to the bedside where it is informative for patients and their healthcare providers.

One thing to keep in mind is that every tissue has its own machinery to make and to break down NAD+. Blood is a convenient material for testing a person’s response to taking TRU NIAGEN®, but it is not necessarily the most relevant tissue for assessing the health benefits of supplementing with NR. We and others are working on less invasive ways to assess NAD+ status in tissues beyond the blood.

We know that TRU NIAGEN is increasing NAD+ safely and effectively in people as this has been demonstrated in several published clinical trials.

Clinical trials:
https://www.nature.com/articles/ncomms12948
https://www.nature.com/articles/s41467-018-03421-7
https://www.ncbi.nlm.nih.gov/pubmed/29992272
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186459

Again, thanks for the excellent question, and your interest in TRU NIAGEN®.
Sincerely,

Cheri Thomas

TN Logo

1-888-642-4361 (1-888-NIAGEN1)

www.TruNiagen.com

[Wildbilly]

Mornings here as well, I do have sleep issues

but those have been ongoing since before I started taking Niagen 2 years ago.

I too would like a baseline but I've been reluctant to tell my Dr.s about taking
Niagen as they are all so anti-supplement in general. I'm working up to it tho'.

[cantwate]

I also take mine first thing in the morning and have no problem sleeping at night. I’ve been taking for about 6-7 months and have experienced a general well being improvement, my memory issues seem to have stabilized but no improvement in joint pain yet.

I talked with and have written the company several times to ask if there is a blood test that actually measures NAD. I wanted a baseline so I could actually see if an increase was indeed measurable. I never received an answer that made sense, only that I should ask my doctor about a blood test. I suggested that in order for them to be able to claim an increase in NAD, they had to be using some sort of measurement to validate their claim. The girl said she would ask their board and get back to me. She did get back to me but only to say their claim was based on intricate scientific data and I’d have to see if my doctor knew of a blood test that measured the levels of NAD.

[Wildbilly]

Yes, Hong Kong, there are others as well.

[jfk]

Thanks. Who. is Pioneer Step (Chinese investors?)?

[Wildbilly]

Pioneer Step Holdings Ltd upped their stake to 9 1/2%

making them the largest stake holder. The 13D of the Schedule 13D/A indicates they're likely to take on an activist role

ie: actively pursue a change in business strategy. I'm sure they too are frustrated with all this litigious stuff, a hostile takeover is also possible

so we may see heads role or an attempt to change the board anyway.

[jfk]

Today's SEC filing: Can someone please explain what it is?? Hard to figure out what it is saying. TIA